Existence of No Hepatocarcinogenic Effect Levels of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline with or without Coadministration with Ethanol

Toxicologic Pathology

Volumn 34, Issue 3, 2006, Pages 232-236

  Wanibuchi, Hideki ^a   Wei, Min ^a   Karim, M Rezaul ^a   Morimura, Keiichirou ^a   Doi, Kenichiro ^a   Kinoshita, Anna ^a   Fukushima, Shoji ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

2 Amino 3,8 dimethylimidazo 4,5 f quinoxaline; cancer risk assessment; ethanol; hepatocarcinogenesis; threshold

Indexed keywords

2 AMINO 3,8 DIMETHYLIMIDAZO[4,5 F]QUINOXALINE; ALCOHOL; GLUTATHIONE S TRANSFERASE PLACENTAL FORM; GLUTATHIONE TRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER RISK; CELL PROLIFERATION; CONTROLLED STUDY; GENOTOXICITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER CARCINOGENESIS; LIVER CARCINOMA; LIVER CELL; LIVER TOXICITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RISK ASSESSMENT; RISK FACTOR;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; CARCINOGENS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DEOXYGUANOSINE; DNA ADDUCTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; GLUTATHIONE S-TRANSFERASE PI; IMMUNOHISTOCHEMISTRY; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; NO-OBSERVED-ADVERSE-EFFECT LEVEL; PROLIFERATING CELL NUCLEAR ANTIGEN; QUINOXALINES; RATS; RATS, INBRED F344;

ANIMALIA;

EID: 33646800845     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/01926230600713632     Document Type: Article

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