Apical localization of ITPK1 enhances its ability to be a modifier gene product in a murine tracheal cell model of cystic fibrosis

Journal of Cell Science

Volumn 119, Issue 7, 2006, Pages 1320-1328

  Yang, Ling ^a   Reece, Jeff ^a   Gabriel, Sherif E ^b   Shears, Stephen B ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

CFTR; Chloride channel; Cystic fibrosis; Inositol phosphate; ITPK1; Secretion

Indexed keywords

CALCIUM ION; CHLORIDE ION; INOSITOL 3,4,5,6 TETRAKISPHOSPHATE KINASE 1; INOSITOL PHOSPHATE; PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL IMMORTALIZATION; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYSTIC FIBROSIS; ENZYME LOCALIZATION; EPITHELIUM CELL; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOFLUORESCENCE MICROSCOPY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STATISTICAL SIGNIFICANCE; TRACHEA MUCOSA; WILD TYPE;

ANIMALS; CELL LINE; CELL MEMBRANE; CELL POLARITY; CYSTIC FIBROSIS; DISEASE MODELS, ANIMAL; FLUORESCENT ANTIBODY TECHNIQUE, DIRECT; FLUORESCENT DYES; INDOLES; INOSITOL PHOSPHATES; MICE; MICROSCOPY, CONFOCAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRACHEA;

ANIMALIA; MURINAE;

EID: 33646794965     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.02836     Document Type: Article

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