Lipophorin receptor of Bombyx mori: cDNA cloning, genomic structure, alternative splicing, and isolation of a new isoform

Journal of Lipid Research

Volumn 47, Issue 5, 2006, Pages 1005-1013

  Gopalapillai, Ravikumar ^a,b   Kadono Okuda, Keiko ^a   Tsuchida, Kozo ^a   Yamamoto, Kimiko ^a   Nohata, Junko ^a   Ajimura, Masahiro ^a   Mita, Kazuei ^a  

^a NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES   (Japan)

^b CENTRAL SILK BOARD   (India)

Author keywords

Isoforms; Lipoprotein receptor; Silkworm

Indexed keywords

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BOMBYX; CLONING, MOLECULAR; INTRONS; MOLECULAR SEQUENCE DATA; PROTEIN ISOFORMS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, LDL; SEQUENCE ALIGNMENT;

EID: 33646791490     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M500462-JLR200     Document Type: Article

References (38)

1. Schneider, W. J., and J. Nimpf. 2003. LDL receptor relatives at the crossroad of endocytosis and signaling. Cell.Mol. Life Sci. 60: 892-903.
2. Herz, J. 2001. The LDL receptor gene family: (un)expected signal transducers in the brain. Neuron. 29: 571-581.
3. Van der Horst, D. J., P. M. Weers, and W. J. A. Van Marrewijk. 1993. Lipoproteins and Lipid Transport. In Insect Lipids: Chemistry, Biochemsitry and Biology. D. W. Stanley-Samuleson and D. R. Nelson, editors. University of Nebraska Press, Lincoln, NE. 1-24.
4. Law, J. H., and M. A. Wells. 1989. Insects as biochemical models. J. Biol. Chem. 264: 16335-16338.
5. Canavoso, L. E., and M. A. Wells. 2001. Role of lipid transfer particle in delivery of diacylglycerol from mid gut to lipophorin in larval Manduca sexta. Insect Biochem. Mol. Biol. 31: 783-790.
6. Van der Horst, D. J., and R. O. Ryan. 2005. Lipid transport. In Comprehensive Molecular Insect Science. Vol. 4. L. I. Gilbert, K. Iatrou, and S. S. Gill, editors. Elsevier, Oxford. 225-246.
7. Dantuma, N. P., M. Potters, M. P. De Winther, C. P. Tensen, F. P. Kooiman, J. Bogerd, and D. J. Van der Horst. 1999. An insect homolog of the vertebrate very low-density lipoprotein receptor mediates endocytosis of lipophorins. J. Lipid Res. 40: 973-978.
8. Van Hoof, D., K. W. Rodenburg, and D. J. Van der Horst. 2002. Insect lipoprotein follows a transferrin-like recycling pathway that is mediated by the insect LDL receptor homologue. J. Cell Sci. 115: 4001-4012.
9. Van Hoof, D., K. W. Rodenburg, and D. J. Van der Horst. 2005. Receptor-mediated endocytosis and intracellular trafficking of lipoproteins and transferrin in insect cells. Insect Biochem. Mol. Biol. 35: 117-128.
10. Tsuchida, K., and M. A. Wells. 1990. Isolation and characterization of a lipophorin receptor from the fat body of an insect, Manduca sexta. J. Biol. Chem. 265: 5761-5767.
11. Cheon, H. M., S. J. Seo, J. Sun, T. W. Sappington, and A. S. Raikhel. 2001. Molecular characterization of the VLDL receptor homolog mediating binding of lipophorin in oocyte of the mosquito, Aedes aegypti. Insect Biochem. Mol. Biol. 31: 753-760.
12. Seo, S. J., H. M. Cheon, J. Sun, T. W. Sappington, and A. S. Raikhel. 2003. Tissue- and stage-specific expression of two lipophorin receptor variants with seven and eight ligand-binding repeats in the adult mosquito. J. Biol. Chem. 278: 41954-41962.
13. Lee, C. S., J. H. Han, B. S. Kim, S. M. Lee, J. S. Hwang, S. W. Kang, B. H. Lee, and H. R. Kim. 2003. Wax moth, Galleria melonella, high-density lipophorin receptor: alternative splicing, tissue-specific expression, and developmental regulation. Insect Biochem. Mol. Biol. 33: 761-771.
14. Schonbaum, C. P., S. Lee, and P. A. Mahowald. 1995. The Drosophila yolkless gene encodes a vitellogenin receptor belonging to the low-density lipoprotein receptor superfamily. Proc. Natl. Acad. Sci. USA. 92: 1485-1489.
15. Sappington, T. W., V. A. Kokoza, W. L. Cho, and A. S. Raikhel. 1996. Molecular characterization of the mosquito vitellogenin receptor reveals unexpected high homology to the Drosophila yolk protein receptor. Proc. Natl. Acad. Sci. USA. 93: 8934-8939.
16. Chen, M. E., D. K. Lewis, L. L. Keeley, and P. V. Pietrantonio. 2004. cDNA cloning and transcriptional regulation of the vitellogenin receptor from the imported fire ant, Solenopsis invicta Buren (Hymenoptera: Formicidae). Insect Mol. Biol. 13: 195-204.
17. Yochem, J., and I. Greenwald. 1993. A gene for a low-density lipoprotein receptor-related protein in the nematode Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA. 90: 4572-4576.
18. Pillai, A., S. Ueno, H. Zhang, and Y. Kato. 2003. Induction of ASABF (Ascaris suum antibacterial factor) -type antimicrobial peptides by bacterial injection: novel members of ASABF in the nematode Ascaris suum. Biochem. J. 371: 663-668.
19. Simmons, T., Y. M. Newhouse, K. S. Arnold, T. L. Innerarity, and K. H. Weisgraber. 1997. Human low-density lipoprotein receptor fragment: successful refolding of a functionally active ligand binding domain produced in Escherichia coli. J. Biol. Chem. 272: 25531-25536.
20. Shapiro, J. P., P. S. Keim, and J. H. Law. 1984. Structural studies on lipophorin, an insect lipoprotein. J. Biol. Chem. 259: 3680-3685.
21. Koike, Y., K. Mita, M. G. Suzuki, S. Meada, H. Abe, K. Osoegawa, P. J. deJong, and T. Shimada. 2003. Genomic sequence of a 320-kb segment of the Z chromosome of Bombyx mori containing a kettin ortholog. Mol. Genet. Genomics. 269: 137-149.
22. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual. 2nd edition. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
23. Thompson, J. D., T. J. Gibson, F. Plewniak, F. Jeanmougin, and D. G. Higgins. 1997. The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 25: 4876-4882.
24. Bujo, H., K. A. Lindstedt, M. Hermann, L. M. Dalamau, J. Nimpf, and W. J. Schneider. 1995. Chicken oocytes and somatic cells express different splice variants of a multifunctional receptor. J. Biol. Chem. 270: 23546-23551.
25. Davis, C. G., A. Elhammer, D. W. Russell, W. J. Schneider, S. Kornfeld, M. S. Brown, and J. L. Goldstein. 1986. Deletion of clustered O-linked carbohydrates does not impair function of low-density lipoprotein receptor in transfected fibroblasts. J. Biol. Chem. 261: 2828-2838.
26. Kondrashov, F. A., and E. V. Koonin. 2001. Origin of alternative splicing by tandemexon duplication.Hum. Mol. Genet. 10: 2661-2669.
27. Mizoguchi, A., Y. Ohashi, K. Hosoda, J. Ishibashi, and H. Kataoka. 2001. Developmental profile of the changes in the prothoracicotrophic hormone titer in hemolymph of the silkworm Bombyx mori: correlation with ecdysteroid secretion. Insect Biochem. Mol. Biol. 31: 349-358.
28. Black, D. L. 2003. Mechanisms of alternative pre-messenger RNA splicing. Annu. Rev. Biochem. 72: 291-336.
29. Sakai, J., A. Hoshino, S. Takahashi, Y. Miura, H. Ishii, H. Suzuki, Y. Kawarabayasi, and T. Yamamoto. 1994. Structure, chromosome location, and expression of the human very low-density lipoprotein receptor gene. J. Biol. Chem. 269: 2173-2182.
30. Tiebel, O., K. Oka, K. Robinson, M. Sullivan, J. Martinez, M. Nakamuta, K. Ishimura-Oka, and L. Chan. 1999. Mouse very low-density lipoprotein receptor (VLDLR): gene structure, tissue-specific expression and dietary and developmental regulation. Atherosclerosis. 145: 239-251.
31. Mita, K., M. Kasahara, S. Sasaki, Y. Nagayasu, T. Yamada, H. Kanamori, N. Namiki, M. Kitagawa, H. Yamashita, Y. Yasukochi, et al. 2004. The genome sequence of silkworm, Bombyx mori. DNA Res. 11: 27-35.
32. Xia, Q., Z. Zhou, C. Lu, D. Cheng, F. Dai, B. Li, P. Zhao, X. Zha, T. Cheng, C. Chai, et al. 2004. A draft sequence for the genome of the domesticated silkworm (Bombyx mori). Science. 306: 1937-1940.
33. Adams, M. D., S. E. Celniker, R. A. Holt, C. A. Evans, J. D. Gocayne, P. G. Amanatides, S. E. Scherer, P. W. Li, R. A. Hoskins, R. F. Galle, et al. 2000. The genome sequence of Drosophila melanogaster. Science. 287: 2185-2195.
34. Kim, D. H., K. Magoori, T. R. Inoue, C. C. Mao, H. J. Kim, H. Suzuki, T. Fujitas, Y. Endo, S. Saeki, and T. Yamamoto. 1997. Exon/intron organization, chromosome localization, alternative splicing, and transcription units of the human apolipoprotein E receptor 2 gene. J. Biol. Chem. 272: 8498-8504.
35. Li, Y., W. Lu, M. P. Marzolo, and G. Bu. 2001. Differential functions of members of the low-density lipoprotein receptor family suggested by their distinct endocytosis rates. J. Biol. Chem. 276: 18000-18006.
36. Stockinger,W., C. Brandes, D. Fasching,M.Hermann,M. Gotthardt, J. Herz, W. Schneider, and J. Nimpf. 2000. The reelin receptor ApoER2 recruits JNK-interacting proteins-1 and -2. J. Biol. Chem. 275: 25625-25632.
37. Wehrli, M., S. T. Dougan, K. Caldwell, L. O'Keefe, S. Schwartz, D. Vaizel-Ohayon, E. Schejter, A. Tomlinson, and S. DiNardo. 2000. Arrow encodes an LDL-receptor- related protein essential for Wingless signaling. Nature. 407: 527-530.
38. Herz, J., and H. H. Bock. 2002. Lipoprotein receptors in the nervous system. Annu. Rev. Biochem. 71: 405-434.