HIV-1 infection alters the retinol-binding protein:transthyretin ratio even in the absence of the acute phase response

Journal of Nutrition

Volumn 136, Issue 6, 2006, Pages 1624-1629

  Baeten, Jared M ^a,d   Wener, Mark H ^a   Bankson, Daniel D ^a   Lavreys, Ludo ^a   Richardson, Barbra A ^a   Mandaliya, Kishorchandra ^b   Bwayo, Job J ^c   McClelland, R Scott ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Department of Obstetrics and Gynaecology   (Kenya)

^c UNIVERSITY OF NAIROBI   (Kenya)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

HIV; Inflammation; Retinol binding protein; Transthyretin; Vitamin A status

Indexed keywords

PREALBUMIN; RETINOL; RETINOL BINDING PROTEIN;

ACUTE PHASE RESPONSE; ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEMOGRAPHY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFLAMMATION; MAJOR CLINICAL STUDY; RANDOMIZED CONTROLLED TRIAL; RETINOL DEFICIENCY; SENSITIVITY AND SPECIFICITY; VITAMIN SUPPLEMENTATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 33646772902     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.1093/jn/136.6.1624     Document Type: Article

References (19)

1. World Bank. World Development Report 1993: Investing in health. New York: Oxford University Press; 1993.
2. de Pee S, Dary O. Biochemical indicators of vitamin A deficiency: serum retinol and serum retinol binding protein. J Nutr. 2002;132: 9 Suppl:2895S-901.
3. Baeten JM, Richardson BA, Bankson DD, Wener MH, Kreiss JK, Lavreys L, Mandaliya K, Bwayo JJ, McClelland RS. Use of serum retinol-binding protein for prediction of vitamin A deficiency: effects of HIV-1 infection, protein malnutrition, and the acute phase response. Am J Clin Nutr. 2004;79:218-25.
4. Tanumihardjo SA. Assessing vitamin A status: past, present and future. J Nutr. 2004;134:290S-3.
5. Rosales FJ, Ross AC. A low molar ratio of retinol binding protein to transthyretin indicates vitamin A deficiency during inflammation: studies in rats and a posterior analysis of vitamin A-supplemented children with measles. J Nutr. 1998;128:1681-7.
6. Navab M, Smith JE, Goodman DS. Rat plasma prealbumin. Metabolic studies on effects of vitamin A status and on tissue distribution. J Biol Chem. 1977;252:5107-14.
7. Filteau SM, Willumsen JF, Sullivan K, Simmank K, Gamble M. Use of the retinol-binding protein: transthyretin ratio for assessment of vitamin A status during the acute-phase response. Br J Nutr. 2000;83:513-20.
8. Zago LB, Dupraz H, Sarchi MI, Rio ME. The molar ratio of retinol-binding protein to transthyretin in the assessment of vitamin A status in adults. Proposal of a cut-off point. Clin Chem Lab Med. 2002;40:1301-7.
9. Rosales FJ, Chau KK, Haskell MH, Shankar AH. Determination of a cutoff value for the molar ratio of retinol-binding protein to transthyretin (RBP:TTR) in Bangladeshi patients with low hepatic vitamin A stores. J Nutr. 2002;132:3687-92.
10. Donnen P, Dramaix M, Brasseur D, Bitwe R, Bisimwa G, Hennart P. The molar ratio of serum retinol-binding protein (RBP) to transthyretin (TTR) is not useful to assess vitamin A status during infection in hospitalised children. Eur J Clin Nutr. 2001;55:1043-7.
11. Baeten JM, McClelland RS, Richardson BA, Bankson DD, Lavreys L, Wener MH, Overbaugh J, Mandaliya K, Ndinya-Achola JO, et al. Vitamin A deficiency and the acute phase response among HIV-1 infected and uninfected women in Kenya. J Acquir Immune Defic Syndr. 2002;31:243-9.
12. Baeten JM, McClelland RS, Overbaugh J, Richardson BA, Emery S, Lavreys L, Mandaliya K, Bankson DD, Ndinya-Achola JO, et al. Vitamin A supplementation and HIV-1 shedding in women: results of a randomized clinical trial. J Infect Dis. 2002;185:1187-91.
13. WHO/UNICEF/IVACG. Vitamin A supplements: a guide to their use in the treatment and prevention of vitamin A deficiency and xerophthalmia. 2nd edition. Geneva: World Health Organization; 1997.
14. Johnson D, Hirschkorn D, Busch MP. Evaluation of four alternative methodologies for determination of absolute CD41 lymphocyte counts. The National Heart, Lung, and Blood Institute Retrovirus Epidemiology Donor Study. J Acquir Immune Defic Syndr Hum Retrovirol. 1995;10:522-30.
15. Bieri JG, Tolliver TJ, Catignani GL. Simultaneous determination of alphatocopherol and retinol in plasma or red cells by high pressure liquid chromatography. Am J Clin Nutr. 1979;32:2143-9.
16. Thurnham DI, McCabe GP, Northrop-Clewes CA, Nestel P. Effects of subclinical infection on plasma retinol concentrations and assessment of prevalence of vitamin A deficiency: meta-analysis. Lancet. 2003;362:2052-8.
17. McNeil BJ, Keller E, Adelstein SJ. Primer on certain elements of medical decision making. N Engl J Med. 1975;293:211-5.
18. Stephensen CB, Gildengorin G. Serum retinol, the acute phase response, and the apparent misclassification of vitamin A status in the third National Health and Nutrition Examination Survey. Am J Clin Nutr. 2000;72:1170-8.
19. UNAIDS/WHO. AIDS Epidemic Update: December 2004. [Cited 2004 December 30]. Available at: http://www.unaids.org/wad2004/EPI_1204_pdf_en/EpiUpdate04_en. pdf.