Synthesis and antibacterial activity of substituted flavones, 4-thioflavones and 4-iminoflavones

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 14, 2006, Pages 4704-4711

  Ullah Mughal, Ehsan ^a   Ayaz, Muhammad ^b   Hussain, Zakir ^c   Hasan, Aurangzeb ^a   Sadiq, Amina ^a   Riaz, Muhammad ^b   Malik, Abdul ^b   Hussain, Samreen ^b   Choudhary, M Iqbal ^b  

^a QUAID I AZAM UNIVERSITY   (Pakistan)

^b HEJ Research Institute of Chemistry   (Pakistan)

^c MAX PLANCK INSTITUTE FOR CHEMICAL ENERGY CONVERSION   (Germany)

Author keywords

4 Iminoflavones; 4 Thioflavones; Antibacterial; Flavones; Synthesis

Indexed keywords

2 (2' IODOPHENYL) 6 BROMO 4H 1 BENZOPYRAN 4 ONE; 2 (2' IODOPHENYL) 6 BROMO 4H 1 BENZOPYRAN 4 THIONE; 2 (2' IODOPHENYL) 6 CHLORO 4H 1 BENZOPYRAN 4 ONE; 2 (2' IODOPHENYL) 6 CHLORO 4H 1 BENZOPYRAN 4 THIONE; 2 (2' IODOPHENYL) 6 FLUORO 4H 1 BENZOPYRAN 4 THIONE; 2 (2',5' DINITROPHENYL) 4H 1 BENZOPYRAN 4 THIONE; 2 (2,4 DINITROPHENYL) 1 (2 (2',5' DINITROPHENYL) 4H CHROMEN 4 YLIDENE)HYDRAZINE; 2 (2,4 DINITROPHENYL) 1 (2 (3' METHOXYPHENYL) 4H CHROMEN 4 YLIDENE)HYDRAZINE; 2 (2,4 DINITROPHENYL) 1 (2 (4' METHOXYPHENYL) 4H CHROMEN 4 YLIDENE)HYDRAZINE; 2 (2,4 DINITROPHENYL) 1 (2 (4' METHYLPHENYL) 4H CHROMEN 4 YLIDENE)HYDRAZINE; 2 (2,4 DINITROPHENYL) 1 (2 (4' NITROPHENYL) 4H CHROMEN 4 YLIDENE)HYDRAZINE; 4 IMINOFLAVONE DERIVATIVE; 4 THIOFLAVONE DERIVATIVE; FLAVONE DERIVATIVE; HALOGEN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; DRUG ACTIVITY; DRUG SYNTHESIS; ESCHERICHIA COLI; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHI; SHIGELLA FLEXNERI; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; BACTERIA; ESCHERICHIA COLI; FLAVONES; MICROBIAL SENSITIVITY TESTS; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHI; SHIGELLA FLEXNERI; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP;

BACILLUS SUBTILIS; ESCHERICHIA COLI; PSEUDOMONAS AERUGINOSA; SALMONELLA; SALMONELLA TYPHI; SHIGELLA;

EID: 33646772838     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.03.031     Document Type: Article

References (19)

1. Harborne J.B., and Williams C.A. Phytochemistry 55 (2000) 481
2. Middleton Jr. E., Kandaswami C., and Theoharides T.C. Pharmacol. Rev. 52 (2000) 673
3. Manthey J.A., Grohmann K., and Guthrie N. Curr. Med. Chem. 8 (2001) 135
4. Rice-Evans C.A., and Miller N.J. Biochem. Soc. Trans. 24 (1996) 790
5. Hollman P.C.H., Hertog M.G.L., and Katan M.B. Biochem. Soc. Trans. 24 (1996) 785
6. Iinuma M., Tsuchiya H., Sato M., Yokoyama J., Ohyama M., Ohkawa Y., Tanaka T., Fujiwara S., and Fujii T. J. Pharm. Pharmacol. 46 (1994) 892
7. Akama T., Shida Y., Sugaya T., Ishida H., Gomi K., and Kasai M. J. Med. Chem. 39 (1996) 3461
8. Raut A.W., Doshi A.G., and Raghuwanshi P.B. Orient J. Chem. 14 (1998) 337
9. Razdan R.K., Bruni R.J., Mehta A.C., Weinhardt K.K., and Papanastassiou Z.B. J. Med. Chem. 21 (1978) 643
10. Bharucha P.B., and Naik H.B. Asian J. Chem. 12 (2000) 318
11. Baker W., and Ollis W.D. Nature 169 (1952) 706
12. Mahal H.S., and Venkataraman K. Curr. Sci. 2 (1933) 214
13. Levai A. Heterocycl. Commun. 5 (1999) 419
14. Mozingo R., and Adkins H. J. Am. Chem. Soc. 60 (1938) 669
15. Waitz J.A., Drube C.G., and Weinstein M.J. J. Antibiotics 25 (1972) 647
16. Kinoshita T., Ichinose K., and Sankawa U. Tetrahedron Lett. 31 (1990) 7355
17. Hideyoshi M., Eizo T., and Mitsuru S. Bull. Chem. Soc. Jpn. 76 (2003) 835
18. Bossert F. Liebigs Ann. Chem. 680 (1964) 40
19. Howell B.A. J. Chem. Edu. 61 (1984) 176