Neurological soft signs as the stroke risk in sickle cell disease

Tohoku Journal of Experimental Medicine

Volumn 209, Issue 2, 2006, Pages 135-140

  Melek, Ismet ^a   Akgul, Ferit ^a   Duman, Taskin ^a   Yalcin, Fatih ^a   Gali, Edip ^b  

^a MUSTAFA KEMAL UNIVERSITY   (Turkey)

^b ANTAKYA STATE HOSPITAL   (Turkey)

Author keywords

Cerebral infarction; Sickle cell; Soft signs

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CEREBROVASCULAR ACCIDENT; CLINICAL PRACTICE; CONTROLLED STUDY; DISEASE COURSE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOTOR COORDINATION; NEUROLOGIC DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; RISK ASSESSMENT; RISK FACTOR; SCORING SYSTEM; SICKLE CELL ANEMIA; SILENT MYOCARDIAL INFARCTION; STATISTICAL SIGNIFICANCE;

ADOLESCENT; ADULT; ANEMIA, SICKLE CELL; CEREBRAL INFARCTION; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MOTOR SKILLS DISORDERS; PERCEPTUAL DISORDERS; PSYCHOMOTOR DISORDERS; STEREOGNOSIS; TELENCEPHALON;

EID: 33646761337     PISSN: 00408727     EISSN: 13493329     Source Type: Journal    
DOI: 10.1620/tjem.209.135     Document Type: Article

References (28)

1. Arango, C., Bartko, J.J., Gold, J.M. & Buchanan, R.W. (1999) Prediction of neuropsychological performance by neurological signs in schizophrenia. Am. J. Psychiatry, 156, 1349-1357.
2. Armstrong, F.D., Thompson, R.J., Wang, W., Zimmerman, R., Pegelow, C.H., Miller, S. Moser, F., Bello, J., Hurting, A. & Vaas, K. (1996) Cognitive functioning and brain magnetic resonance imaging in children with sickle cell disease. Neuropsychology Committee of the Cooperative Study of Sickle Cell Disease. Pediatrics, 97, 864-870.
3. Bolton, D., Gibb, W., Lees, A., Raven, P., Gray, A., Chen, E. & Shafran, R. (1998) Neurological soft signs in obsessive compulsive disorder: standardised assessment and comparison with schizophrenia. Behav. Neurol., 11, 197-204.
4. Buchanan, R.W. & Heinrichs, D.W. (1989) The Neurological Evaluation Scale (NES): a structured instrument for the assesment of neurological signs in schizophrenia. Psychiatry Res., 27, 335-350.
5. Dazzan, P., Morgan, K.D., Orr, K.G., Hutchinson, G., Chitnis, X., Suckling, J., Fearon, P., Salvo, J., McGuire, P.K., Mallett, R.M., Jones, P.B., Leff, J. & Murray, R.M. (2004) The structural brain correlates of neurological soft signs in AESOP first-episode psychoses study. Brain, 127, 143-153.
6. Giele, J.L., Witkamp, T.D., Mali, W.P. & van der Graaf, Y. (2004) SMART Study Group Silent brain infarcts in patients with manifest vascular disease. Stroke, 35, 742-746.
7. Gupta, S., Andreasen, N.C., Arndt, S., Flaum, M., Schultz, S.K., Hubbard, W.C. & Smith, M. (1995) Neurological soft signs in neuroleptic-naive and neuroleptic treated schizophrenic patients and in normal comparison subjects. Am. J. Psychiatry, 152, 191-196.
8. Hoppe, C. (2005) Defining stroke risk in children with sickle cell anaemia. Br. J. Haematol., 128, 751-766.
9. King, D.J, Wilson, A., Cooper, S.J. & Waddington, J.L. (1991) The clinical correlates of neurological soft signs in chronic schizophrenia. Br. J. Psychiatr., 158, 770-775.
10. Kinney, T.R., Sleeper, L.A., Wang, W.C., Zimmerman, R.A., Pegelow, C.H., Ohene-Frempong, K., Wethers, D.L., Bello, J.A., Vichinsky, E.P., Moser, F.G., Gallagher, D.M., DeBaun, M.R., Platt, O.S. & Miller S.T. (1999) Silent cerebral infarcts in sickle cell anemia: a risk factor analysis. Pediatrics, 103, 640-645.
11. Kral, M.C., Brown, R.T., Nietert, P.J., Abboud, M.R., Jackson, S.M. & Hynd, G.W. (2003) Transcranial Doppler ultrasonography and neurocognitive functioning in children with sickle cell disease. Pediatrics, 112, 324-331.
12. Kugler, S., Anderson, B., Cross, D., Sharif, Z., Sano, M., Haggerty, R., Prohovnik, I., Hurlet-Jensen, A., Hilal, S. & Mohr, J.P. (1993) Abnormal cranial magnetic resonance imaging scans in sickle-cell disease. Neurological correlates and clinical implications. Arch. Neurol., 50, 629-635.
13. Kuller, L.H., Longstreth, W.T., Jr., Arnold, A.M., Bernick, C., Bryan, R.N. & Beauchamp, N.J. (2004) Cardiovascular Health Study Collaborative Research Group White matter hyperintensity on cranial magnetic resonance imaging: a predictor of stroke. Stroke, 35, 1821-1825.
14. Mercuri, E., Fandez, J.C., Roberts, I., Flora, S., Bouza, H., Cowan, F., Pennock, J., Bydder, G. & Dubowitz, L. (1995) Neurological 'soft' signs may identify children with sickle cell disease who are at risk for stroke. Eur. J. Ped., 154, 150-156.
15. Moser, F.G., Miller, S.T., Bello, J.A., Pegelow, C.H., Zimmerman, R.A., Wang, W.C., Ohene-Frempong, K., Schwartz, A., Vichinsky, E.P., Gallagher, D. & Kinney, T.R. (1996) The spectrum of brain MR abnormalities in sickle-cell disease: a report from the Cooperative Study of Sickle Cell Disease. Am. J. Neuroradiol., 17, 965-972.
16. Negash, A., Kebede, D., Alem, A., Melaku, Z., Deyessa, N., Shibrie, T., Fekadu, A., Jacobbson, L. & Kullgren, G. (2004) Neurological soft signs in bipolar I disorder patients. J. Affect. Disord., 80, 221-230.
17. Ohene-Frempong, K., Weiner, S.J., Sleeper, L.A., Miller, S.T., Embury, S., Moohr, J.W., Wethers, D.L., Pegelow, C.H. & Gill, F.M. (1998) Cerebrovascular accidents in sickle cell disease: rates and risk factors. Blood, 91, 288-294.
18. Pavlakis, SG., Bello, J., Prohovnik, I., Sutton, M., Ince, C., Mohr J.P., Piomelli, S., Hilal, S. & De Vivo, D.C. (1988) Brain infarction in sickle cell anemia: magnetic resonance imaging correlates. Ann. Neurol., 23, 125-130.
19. Pegelow, C.H., Wang, W., Granger, S., Hsu, L.L., Vichinsky, E., Moser, F.G., Bello, J., Zimmerman, R.A., Adams, R.J. & Brambilla, D. (2001) STOP Trial Silent infarcts in children with sickle cell anemia and abnormal cerebral artery velocity. Arch. Neurol., 58, 2017-2021.
20. Pegelow, C.H., Macklin, E.A., Moser, F.G., Wang, W.C., Bello J.A., Miller S.T., Vichinsky, E.P., DeBaun, M.R., Guarini, L., Zimmerman, R.A., Younkin, D.P., Gallagher, D.M. & Kinney, T.R. (2002) Longitudinal changes in brain magnetic resonance imaging findings in children with sickle cell disease. Blood, 15, 3014-3018.
21. Powars, D.R., Conti, P.S., Wong, W.Y., Groncy, P., Hyman, C., Smith, E., Ewing, N., Keenan, R.N., Zee, C.S., Harold, Y., Hiti, A.L., Teng, E.L. & Chan, L.S. (1999) Cerebral vasculopathy in sickle cell anemia: diagnostic contribution of positron emission tomography. Blood, 93, 71-79.
22. Sarnaik, S.A. (2005) Sickle cell diseases: current therapeutic options and potential pitfalls in preventive therapy for transcranial Doppler abnormalities. Pediatr. Radiol., 35, 223-228.
23. Schroder, J., Niethammer, R., Geider, F., Reitz, C., Binkert, M., Jauss, M. & Sauer, H. (1991) Neurological soft signs in schizophrenia. Schizophr. Res., 6, 25-30.
24. Schroder, J., Wenz, F., Schad, L.R., Baudendistel, K. & Knopp, M.V. (1995) Sensorimotor cortex and supplementary motor area changes in schizophrenia; A study with functional magnetic resonance imaging. Br. J. Psychiatr., 167, 197-201.
25. Schroder, J., Essig, M., Baudendistel, K., Jahn, T., Gerdsen, I., Stockert, A., Schad, L.R. & Knopp, M.V. (1999) Motor dysfunction and sensorimotor cortex activation changes in schizophrenia: A study with functional magnetic resonance imaging. Neuroimage, 9, 81-87.
26. Sevincok, L., Akoglu, A., Topaloglu, B. & Aslantas, H. (2004) Neurological soft signs in schizophrenic patients with obsessive-compulsive disorder. Psychiatry Clin. Neurosci., 58, 274-279.
27. Shibre, T., Kebede, D., Alem, A., Kebreab, S., Melaku, Z., Deyessa, N., Negash, A., Fekadu, A., Fekadu, D., Medhin, G., Negeri, C., Jabobsson, L. & Kullgren, G. (2002) Neurological soft signs (NSS) in 200 treatment-naive cases with schizophrenia: a community-based study in a rural setting. Nord. J. Psychiatry, 56, 425-431.
28. Wang, W.C., Langston, J.W., Steen, R.G., Wynn, L.W., Mulhern, R.K., Wilimas, J.A., Kim, F.M. & Figueroa, R.E. (1998) Abnormalities of central nervous system in very young children with sickle cell anemia. J. Pediatrics, 132, 994-998.