Physical activity, insulin sensitivity, and hypertension among US adults: Findings from the insulin resistance atherosclerosis study

American Journal of Epidemiology

Volumn 163, Issue 10, 2006, Pages 921-928

  Foy, Capri Gabrielle ^a   Foley, Kristie Long ^a   D'Agostino Jr , Ralph B ^a   Goff Jr , David C ^a   Mayer Davis, Elizabeth ^b   Wagenknecht, Lynne E ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Adult; Aged; Exercise; Hypertension; Insulin; Insulin resistance

Indexed keywords

HEALTH IMPACT; HYPERTENSION;

ADULT; AGED; ARTICLE; ATHEROSCLEROSIS; CLINICAL STUDY; DISEASE ASSOCIATION; ENERGY EXPENDITURE; FEMALE; HUMAN; HYPERTENSION; INSULIN RESISTANCE; INSULIN SENSITIVITY; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; PHYSICAL ACTIVITY; PREVALENCE; SITTING; UNITED STATES;

ADULT; AGED; ATHEROSCLEROSIS; CHI-SQUARE DISTRIBUTION; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; HYPERTENSION; INSULIN RESISTANCE; MALE; MIDDLE AGED; MOTOR ACTIVITY; PREVALENCE; PROSPECTIVE STUDIES; RISK FACTORS; UNITED STATES;

EID: 33646736522     PISSN: 00029262     EISSN: 14766256     Source Type: Journal    
DOI: 10.1093/aje/kwj113     Document Type: Article

References (38)

1. Zimmet P, Boyko EJ, Collier GR, et al. Etiology of the metabolic syndrome: potential role of insulin resistance, leptin resistance, and other players. Ann NY Acad Sci 1999;892:25-44.
2. Reaven G. Metabolic syndrome: pathophysiology and implications for management of cardiovascular disease. Circulation 2002;16:286-8.
3. Grundy SM. Hypertriglyceridemia, insulin resistance, and the metabolic syndrome. Am J Cardiol 1999;83:25F-9F.
4. Thomas GN, Hong AW, Lam CW, et al. Increasing insulin resistance contributes to worsening glycaemic and lipid profiles in older Chinese subjects. Diabetes Res Clin Pract 2004;64:123-8.
5. Goff DC Jr, Zaccaro DJ, Haffner SM, et al. Insulin sensitivity and the risk of incident hypertension: insights from the Insulin Resistance Atherosclerosis Study. Diabetes Care 2003;26:805.
6. Muller DC, Elahi D, Pratley RE, et al. An epidemiological test of the hyperinsulinemia-hypertension hypothesis. J Clin Endocrinol Metab 1993;76:544-8.
7. Haffner SM, D'Agostino RB Jr, Saad MF, et al. Increased insulin resistance and insulin secretion in nondiabetic African-Americans and Hispanics compared with non-Hispanic whites. The Insulin Resistance Atherosclerosis Study. Diabetes 1996;45:742-8.
8. Haffner SM. Insulin and blood pressure: fact or fantasy? J Clin Endocrinol Metab 1993;76:541-3.
9. Snorgaard O, Kober L, Carlsen J. The effect of metformin on blood pressure and metabolism in nondiabetic hypertensive patients. J Intern Med 1998;242:407-12.
10. Reaven GM. Insulin resistance may or may not play a role in blood pressure regulation. J Intern Med 1998;244:359-60.
11. Suzuki M, Kimura Y, Tsushima M, et al. Association of insulin resistance with salt sensitivity and nocturnal fall of blood pressure. Hypertension 2000;35:864-8.
12. Brett SE, Ritter JM, Chowienczyk PJ. Diastolic blood pressure changes during exercise positively correlate with serum cholesterol and insulin resistance. Circulation 2000;101:611-15.
13. Phillips RA, Krakoff LR, Dunaif A, et al. Relation among left ventricular mass, insulin resistance, and blood pressure in nonobese subjects. J Clin Endocrinol Metab 1998;83:4284-8.
14. Houmard JA, Tanner CJ, Slentz CA, et al. Effect of the volume and intensity of exercise training on insulin sensitivity. J Appl Physiol 2004;96:101-6.
15. Holloszy JO, Schultz J, Kusnierkiewicz J, et al. Effects of exercise on glucose tolerance and insulin resistance. Brief review and some preliminary results. Acta Med Scand Suppl 1986;711:55-65.
16. Mayer-Davis EJ, D'Agostino R Jr, Karter AJ, et al. Intensity and amount of physical activity in relation to insulin sensitivity: The Insulin Resistance Atherosclerosis Study. JAMA 1998;279:669-74.
17. Paffenbarger RS Jr, Wing AL, Hyde RT, et al. Physical activity and incidence of hypertension in college alumni. Am J Epidemiol 1983;117:245-57.
18. Paffenbarger RS Jr, Jung DL, Leung RW, et al. Physical activity and hypertension: an epidemiological view. Ann Med 1991;23:319-27.
19. Hayashi T, Tsumura K, Suematsu C, et al. Walking to work and the risk for hypertension in men: The Osaka Health Survey. Ann Intern Med 1999;131:21-6.
20. Pate RR, Pratt M, Blair SN, et al. Physical activity and public health. A recommendation from the Centers for Disease Control and Prevention and the American College of Sports Medicine. JAMA 1995;273:402-7.
21. Pescatello LS, Franklin BA, Fagard R, et al. American College of Sports Medicine Position Stand. Exercise and hypertension. Med Sci Sports Exerc 2004;36:533-53.
22. Wagenknecht LE, Mayer EJ, Rewers M, et al. The Insulin Resistance Atherosclerosis Study (IRAS): objectives, design, and recruitment results. Ann Epidemiol 1995;5:464-72.
23. World Health Organization. Diabetes mellitus: report of a WHO study group. Geneva, Switzerland: World Health Organization, 1985. (WHO Technical Report Series no. 727).
24. Chobanian AV, Bakris GL, Black HR, et al. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. JAMA 2003;289:2560-72.
25. Ainsworth BE, Haskell WL, Leon AS, et al. Compendium of physical activities: classification of energy costs of human physical activities. Med Sci Sports Exerc 1993;25:71-80.
26. Bell RA, D'Agostino RB Jr, Mayer-Davis EJ, et al. Associations between alcohol consumption and insulin sensitivity and cardiovascular disease risk factors. Diabetes Care 2000;23:1630-6.
27. Whelton SP, Chin A, Xin X, et al. Effect of aerobic exercise on blood pressure: a meta-analysis of randomized, controlled trials. Ann Intern Med 2002;136:493-503.
28. Fagard RH. Exercise characteristics and the blood pressure response to dynamic physical training. Med Sci Sports Exerc 2001;33(suppl):S484-92.
29. Huonker M, Halle M, Keul J. Structural and functional adaptations of the cardiovascular system by training. Int J Sports Med 1996;17(suppl 3):S164-72.
30. Wijnen JA, Kuipers H, Kool MJ, et al. Vessel wall properties of large arteries in trained and sedentary subjects. Basic Res Cardiol 1991;86(suppl 1):25-9.
31. Dinenno FA, Tanaka H, Monahan KD, et al. Regular endurance exercise induces expansive arterial remodelling in the trained limbs of healthy men. J Physiol (Lond) 2001;534:287-95.
32. Meredith IT, Friberg P, Jennings L. Exercise training lowers resting renal but not cardiac sympathetic activity in humans. Hypertension 1991;18:575-82.
33. Higashi Y, Sasaki S, Kurisu S. Regular aerobic exercise augments endothelium dependent vascular relaxation in normotensive as well as hypertensive subjects: role of endothelium-derived nitric oxide. Circulation 1999;100:1194-202.
34. Kingwell BA. Nitric oxide-mediated metabolic regulation during exercise: effects of training in health and cardiovascular disease. FASEB J 2000;14:1685-96.
35. Schmitz KH, Jacobs DR, Hong C-P, et al. Association of physical activity with insulin sensitivity in children. Int J Obes 2002;26:1310-16.
36. Perseghin G, Price TB, Petersen KF, et al. Increased glucose transport-phosphorylation and muscle glycogen synthesis after exercise training in insulin-resistant subjects. N Engl J Med 1996;335:1357-62.
37. Cruz ML, Huang TT, Johnson MS, et al. Insulin sensitivity and blood pressure in black and white children. Hypertension 2002;40:18-22.
38. Landsberg L. Insulin-mediated sympathetic stimulation: role in the pathogenesis of obesity-related hypertension (or how insulin affects blood pressure, and why). J Hypertens 2001;19:523-8.