Maspin expression and localization impact on angiogenesis and prognosis in ovarian cancer

Gynecologic Oncology

Volumn 101, Issue 3, 2006, Pages 385-389

  Solomon, L A ^a   Munkarah, A R ^a   Schimp, V L ^a   Arabi, M H ^b   Morris, R T ^a   Nassar, H ^b   Ali Fehmi, R ^b  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

Author keywords

Angiogenesis; Maspin; Ovarian carcinoma; Vascular endothelial growth factor

Indexed keywords

CD34 ANTIGEN; CYCLOOXYGENASE 2; MASPIN; PARAFFIN; VASCULOTROPIN; SERINE PROTEINASE INHIBITOR; VASCULOTROPIN A;

ADULT; AGED; ANGIOGENESIS; ARTICLE; CANCER STAGING; CANCER SURVIVAL; CELL DENSITY; CELLULAR DISTRIBUTION; CHI SQUARE TEST; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KAPLAN MEIER METHOD; MAJOR CLINICAL STUDY; OVARY CANCER; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; REGRESSION ANALYSIS; BIOSYNTHESIS; CYSTADENOCARCINOMA; METABOLISM; MIDDLE AGED; NEOVASCULARIZATION (PATHOLOGY); OVARY TUMOR; PATHOLOGY; TUMOR SUPPRESSOR GENE; VASCULARIZATION;

ADULT; AGED; AGED, 80 AND OVER; CYCLOOXYGENASE 2; CYSTADENOCARCINOMA, SEROUS; FEMALE; GENES, TUMOR SUPPRESSOR; HUMANS; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; OVARIAN NEOPLASMS; PROGNOSIS; SERPINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33646716983     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2005.11.049     Document Type: Article

References (22)

1. Zhang M., Volpert O., Shi Y.H., and Bouck N. Maspin is an angiogenesis inhibitor. Nat. Med. 6 2 (2000) 196-199
2. Sheng S., Carey J., Seftor E.A., Dias L., Hendrix M.J., and Sager R. Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostate cancer cells. Proc. Natl. Acad. Sci. 93 21 (1996) 11669-11674
3. Liu J., Yin S., Reddy N., Spencer C., and Sheng S. Bax mediates the apoptosis-sensitizing effect of maspin. Cancer Res. 64 5 (2004) 1703-1711
4. Jiang N., Meng Y., Zhang S., Mensah-Osman E., and Sheng S. Maspin sensitizes breast carcinoma cells to induced apoptosis. Oncogene 21 (2002) 4089-4098
5. Zou Z., Anisowicz A., Hendrix M.J., Thor A., Neveu M., Sheng S., et al. Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells. Science 263 5146 (1994) 526-529
6. Abraham S., Zhang W., Greenberg N., and Zhang M. Maspin functions as a tumor suppressor by increasing cell adhesion to extracellular matrix in prostate tumor cells. J. Urol. 169 (2003) 1157-1161
7. Maass N., Hojo T., Ueding M., Luttges J., Kloppel G., Jonat W., et al. Expression of the tumor suppressor gene maspin in human pancreatic cancers. Clin. Cancer Res. 7 4 (2001) 812-817
8. Sood A.K., Fletcher M.S., Gruman L.M., Coffin J.E., Jabbari S., and Khalkhali-Ellis Z. The paradoxical expression of maspin in ovarian carcinoma. Clin. Cancer Res. 8 9 (2002) 2924-2932
9. Raspollini M.R., Amunni G., Villanucci A., Baroni G., Boddi V., and Taddei G.L. Prognostic significance of microvessel density and vascular endothelial growth factor expression in advanced ovarian serous carcinoma. Int. J. Gynecol. Cancer 14 5 (2004) 815-823
10. Masunaga R., Kohno H., Dhar D.K., Ohno S., Shibakita M., Kinugasa S., et al. Cyclooxygenase-2 expression correlates with tumor neovascularization and prognosis in human colorectal carcinoma patients. Clin. Cancer Res. 6 10 (2000) 4064-4068
11. Uefuji K., Ichikura T., and Mochizuki H. Cyclooxygenase-2 expression is related to prostaglandin biosynthesis and angiogenesis in human gastric cancer. Clin. Cancer Res. 6 1 (2000) 135-138
12. Gallo O., Franchi A., Magnelli, Sardi L., Vannacci A., Boddi V., et al. Cyclooxygenase-2 pathway correlates with VEGF expression in head and neck cancer. Implications for tumor angiogenesis and metastasis. Neoplasia 3 1 (2001) 53-61
13. Cao Q.J., Einstein M.H., Anderson P.S., Runowicz C.D., Balan R., and Jones J.G. Expression of COX-2, Ki-67, cyclin D1 and P21 in endometrial endometrioid carcinomas. Int. J. Gynecol. Pathol. 21 2 (2002) 147-154
14. Ali-Fehmi R., Morris R.T., Bandyopadhyay S., Che M., Schimp V., Malone Jr. J.M., et al. Expression of cyclooxygenase-2 in advanced stage ovarian serous carcinoma: correlation with tumor cell proliferation, apoptosis, angiogenesis, and survival. Am. J. Obstet. Gynecol. 192 3 (2005) 819-825
15. Raspollini M.R., Amunni G., Villanncci A., Boddi V., Baroni G., Taddei A., et al. COX-2 status in relation to tumor microvessel density and VEGF expression: analysis in ovarian carcinoma patients with low versus high survival rates. Oncol. Rep. 11 2 (2004) 309-313
16. Ali-Fehmi R., Che M., Khalifeh I., Malone J.M., Morris R., Lawrence D., et al. The effect of cyclooxygenase-2 expression on tumor vascularity in advanced stage ovarian serous carcinoma. Cancer 98 7 (2003) 1423-1429
17. Mohsin S.K., Zhang M., Clark G.M., and Allred D.C. Maspin expression in invasive breast cancer: association with other prognostic factors. J. Pathol. 199 4 (2003) 432-435
18. Wang M.C., Yang Y.M., Li X.H., Dong F., and Li Y. Maspin expression and its clincopathological significance in tumorigenesis and progression of gastric cancer. World J. Gastroentereol. 10 1 (2004) 634-637
19. Song S.Y., Lee S.K., Kim D.H., Son H.J., Kim H.J., Lim Y.J., et al. Expression of maspin in colon cancers: its relationship with p53 expression and microvessel density. Dig. Dis. Sci. 47 8 (2002) 1831-1835
20. Li J.J., Chen Y., Zhang S.M., Wu D.Y., Wang Y.P., and Xin Y. Pathobiological significance of vascular endothelial growth factor and maspin expressions in human gastric carcinoma. World J. Gastroentereol. 10 18 (2004) 2624-2627
21. Zhu G., Saed G.M., Deppe G., Diamond M.P., and Munkarah A.R. Hypoxia up-regulates the effects of prostaglandin E2 on tumor angiogenesis in ovarian cancer cells. Gynecol. Oncol. 94 2 (2004) 422-426
22. Al-Ayyoubi M., Gettins P.G.W., and Volz K. Crystal structure of human maspin, a serpin with antitumor properties: reactive center loop of maspin is exposed but constrained. J. Biol. Chem. 279 53 (2004) 55540-55544