Spinal reflex control of micturition after spinal cord injury

Restorative Neurology and Neuroscience

Volumn 24, Issue 2, 2006, Pages 69-78

  Tai, Changfeng ^a   Roppolo, James R ^a   De Groat, William C ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Bladder; Electrical stimulation; Lower urinary tract; Spinal cord injury; Spinal reflex; Urethra; Urethral sphincter

Indexed keywords

BOTULINUM TOXIN A; CAPSAICIN; MUSCARINIC RECEPTOR BLOCKING AGENT; OXYBUTYNIN; RESINIFERATOXIN; SOLIFENACIN; TOLTERODINE;

BIBLIOGRAPHIC DATABASE; BLADDER DISEASE; BLADDER SURGERY; DETRUSOR DYSSYNERGIA; DORSAL RHIZOTOMY; ELECTROSTIMULATION; HUMAN; HYPERREFLEXIA; INTESTINAL DYSMOTILITY; MEDLINE; MICTURITION; PRIORITY JOURNAL; PUDENDAL NERVE; RESIDUAL URINE; REVIEW; SPINAL CORD INJURY; SPINAL REFLEX; SYSTEMATIC REVIEW; URETHRA DISEASE; URINE INCONTINENCE; VISUAL DISORDER; WEB OF SCIENCE; XEROSTOMIA;

ANIMALS; HUMANS; MODELS, BIOLOGICAL; MUSCLE, SMOOTH; REFLEX; SPINAL CORD INJURIES; URINARY BLADDER; URINARY INCONTINENCE;

EID: 33646684726     PISSN: 09226028     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (129)

1. A.S. Burns, D.A. Rivas and J.F. Ditunno, The management of neurogenic bladder and sexual dysfunction after spinal cord injury, Spine suppl. 26 (2001), s129-s136.
2. F. Jamil, Toward a catheter free status in neurogenic bladder dysfunction: a review of bladder management options in spinal cord injury (SCI), Spinal Cord 39 (2001), 355-361.
3. P. Hallin, M. Sullivan and M. Kreuter, Spinal cord injury and quality of life measures: a review of instrument psychometric quality, Spinal Cord 38 (2000), 509-523.
4. N.T. North, The psychological effects of spinal cord injury: a review, Spinal Cord 37 (1999), 671-679.
5. E. Iwatsubo, T. Koyanagi, J.J. Wyndaele, W.S. El Masri and A.C. Diokno, Urological management of tetraplegic patients, Spinal Cord 37 (1999), 1-5.
6. W.C. de Groat, A.M. Booth and N. Yoshimura, Neurophysiology of micturition and its modification in animal models of human disease, in: The Autonomic Nervous System, Nervous Control of the Urogenital System, (Vol. 3), C.A. Maggi, eds, Harwood Academic Publishers, London, 1993, pp. 227-289.
7. W.C. de Groat, Nervous control of the urinary bladder of the cat, Brain Res. 87 (1975), 201-211.
8. W.C. de Groat, M.O. Fraser, M. Yoshiyama, S. Smerin, C. Tai, M.B. Chancellor, N. Yoshimura and J.R. Roppolo, Neural control of the urethra, Scand. J. Urol. Nephrol. suppl. 207 (2001), 35-43.
9. S.J. Shefchyk, Spinal cord neural organization controlling the urinary bladder and striated sphincter, Progress in Brain Research 137 (2002), 71-82.
10. M. Graggs and J. McFarlane, Neuromodulation of the lower urinary tract, Exp. Physiol. 84 (1999), 149-160.
11. W.M. Grill, M.D. Graggs, R.D. Forman, D.L. Ludlow and J.L. Buller, Emerging clinical applications of electrical stimulation: opportunities for restoration of function, J. Rehab. Res. and Develop. 38 (2001), 641-653.
12. N. Yoshimura, C.P. Smith, M.B. Chancellor and W.C. de Groat, Pharmacologic and potential biologic interventions to restore bladder function after spinal cord injury, Current Opinion in Neurology 13 (2000), 677-681.
13. M. Fall and S. Lindstrom, Electrical stimulation: a physiologic approach to the treatment of urinary incontinence, Urol. Clin. North Am. 18 (1991), 393-407.
14. M. Fall, B.E. Erlandson, C.A. Carlsson and S. Lindstrom, The effect of intravaginal electrical stimulation on the feline urethra and urinary bladder: neuronal mechanisms, Scand. J. Urol. Nephrol. suppl. 44 (1978), 19-30.
15. S. Lindstrom, M. Fall, C.A. Carlsson and B.E. Erlandson, The neurophysiological basis of bladder inhibition in response to intravaginal electrical stimulation, J. Urol. 129 (1983), 405-410.
16. A.P.S. Kirkham, S.L. Knight, M.D. Craggs, A.T.M. Casey and P.J.R. Shah, Neuromodulation through sacral nerve roots 2 to 4 with a Finetech-Brindley sacral posterior and anterior root stimulator, Spinal Cord 40 (2002), 272-281.
17. A.P.S. Kirkham, N.C. Shah, S.L. Knight, P.J.R. Shah and M.D. Craggs, The acute effects of continuous and conditional neuromodulation on the bladder in spinal cord injury, Spinal Cord 39 (2001), 420-428.
18. E.J. Chartier-Kastler, J.L.H. Ruud Bosch, M. Perrigot, M.B. Chancellor, F. Richard and P. Denys, Long-term results of sacral nerve stimulation (S3) for the treatment of neurogenic refractory urge incontinence related to detrusor hyperreflexia, J. Urol. 164 (2000), 1476-1480.
19. E.J. Chartier-Kastler, P. Denys, M.B. Chancellor, A. Haertig, B. Bussel and F. Richard, Urodynamic monitoring during percutaneous sacral nerve neurostimulation in patients with neurogenic detrusor hyperreflexia, Neurourol. Urodynam. 20 (2001), 61-71.
20. M. Ishigooka, Y. Suzuki, T. Hashimoto, I. Sasagawa, T. Nakada and Y. Handa, A new technique for sacral nerve stimulation: a percutaneous method for urinary incontinence caused by spinal cord injury, Br. J. Urol. 81 (1998), 315-318.
21. J.G. Previnaire, J.M. Soler, M. Perrigot, G. Boileau, H. Delahaye, P. Schumacker, J. Vanvelcenaher and J.L. Vanhee, Short-term effect of pudendal nerve electrical stimulation on detrusor hyperreflexia in spinal cord injury patients: importance of current strength, Paraplegia 34 (1996), 95-99.
22. I.K. Walsh, T. Thompson, W.G.G. Loughridge, S.R. Johnston, P.F. Keane and A.R. Stone, Non-invasive antidromic neurostimulation: a simple effective method for improving bladder storage, Neurourol. Urodynam. 20 (2001), 73-84.
23. M.K.M. Sheriff, P.J.R. Shah, C. Fowler, A.R. Mundy and M.D. Graggs, Neuromodulation of detrusor hyper-reflexia by functional magnetic stimulation of the sacral roots, Br. J. Urol. 78 (1996), 39-46.
24. M.D. Chancellor, J. Gajewski, C.F.D. Ackman, R.A. Appell, J. Bennett, J. Binard, T.B. Boone, M.P. Chetner, J.A. Crewalk, A. Defalco, J. Foote, B. Green, S. Juma, S.Y. Jung, T.A. Linsenmeyer, R. MacMillan, M. Mayo, H. Ozawa, C.G. Roehrborn, P.J. Shenot, A. Stone, A. Vazquez, W. Killorin and D.A. Rivas, Long-term follow-up of the north American multicenter UroLume trial for the treatment of external detrusor-sphincter dyssynergia, J. Urol. 161 (1999), 1545-1550.
25. S.V. Yalla, K.J. Blunt, B.A. Fam, N.I. Constantinople and R.F. Gittes, Detrusor-urethral sphincter dyssynergia, J. Urol. 118 (1997), 1026-1029.
26. J.G. Blaivas, The neurophysiology of micturition: a clinical study of 550 patients, J. Urol. 127 (1982), 958-963.
27. S.V. Yalla, A.B. Rossier and B. Fam, Dyssynergic vesicourethral responses during bladder rehabilitation in spinal cord injury patients: effects of suprapubic percussion, crede method and bethanechol chloride, J. Urol. 115 (1976), 575-579.
28. E. McGuire, Urethral sphincter mechanisms, Urol. Clin. North Am. 6 (1979), 39-48.
29. J.M. Park, D.A. Bloom and E.J. McGuire, The guarding reflex revisited, Brit. J. Urol. 80 (1997), 940-945.
30. M.B. Siroky and R.J. Krane, Neurologic aspects of detrusorsphincter dyssynergia, with reference to the guarding reflex, J. Urol. 127 (1982), 953-957.
31. D. Denny-Brown and E.G. Robertson, The state of the bladder and its sphincter in complete transverse lesions of the spinal cord and cauda equina, Brain 56 (1933), 397-469.
32. E.J. McGuire and S. Brady, Detrusor-sphincter dyssynergia, J. Urol. 121 (1979), 774-777.
33. J.G. Blaivas, H.P. Sinha, A.A.H. Zayed and K.B. Labib, Detrusor-external sphincter dyssynergia, J. Urol. 125 (1981), 542-544.
34. E. Iwatsubo, Bladder recovery in patients with traumatic cervical cord injury evaluated by voiding synchronous cystosphincterometry with uroflowmetry, J. Urol. 126 (1981), 503-508.
35. S.V. Yalla, A.B. Rossier and B. Fam, Dyssynergic vesicourethral responses during bladder rehabilitation in spinal cord injury patients: effects of suprapubic percussion, crede method and bethanechol chloride, J. Urol. 115 (1976), 575-579.
36. J.G. Blaivas, H.P. Sinha, A.A.H. Zayed and K.B. Labib, Detrusor-external sphincter dyssynergia: a detailed electromyographic study, J. Urol. 125 (1981), 545-548.
37. M.R. Bulter, Patterns of bladder recovery in spinal injury evaluated by serial urodynamic observations, Urology 6 (1978), 308-314.
38. J.S. Walter, J.S. Wheeler, R.D. Wurster, J. Sacks and R. Dunn, Preliminary observations of a synergistic bladder-sphincter relationship following spinal cord injury in a quadruped animal, J. Spinal Cord Med. 26 (2003), 372-379.
39. G. Rampal and P. Mignard, Behaviour of the urethral striated sphincter and of the bladder in the chronic spinal cat: implications at the central nervous system level, Pflugers Arch. 353 (1975), 33-42.
40. R.C. Garry, T.D.M. Roberts and J.K. Todd, Reflexes involving the external urethral sphincter in the cat, J. Physiol. 149 (1959), 653-665.
41. S.J. Shefchyk and R.R. Buss, Urethral pudendal afferent-evoked bladder and sphincter reflexes in decerebrate and acute spinal cats, Neurosci. Lett. 244 (1998), 137-140.
42. W.E. Bradley and C.T. Teague, Synaptic events in pudendal motoneurons of the cat, Exp. Neurol. 56 (1977), 237-240.
43. W.E. Bradley and C.T. Teague, Electrophysiology of pelvic and pudendal nerves in the cat, Exp. Neurol. 35 (1972), 378-393.
44. R.E. Mackel, Segmental and descending control of the external urethral and anal sphincters in the cat, J. Physiol. 294 (1979), 105-122.
45. A. Reitz, D.M. Schmid, A. Curt, P.A. Knapp and B. Schurch, Afferent fibers of the pudendal nerve modulate sympathetic neurons controlling the bladder neck, Neurourol. Urodyn. 22 (2003), 597-601.
46. Y. Wu, J.B. Nanninga and B.B. Hamilton, Inhibition of the external urethral sphincter and sacral reflex by anal stretch in spinal cord injured patients, Arch. Phys. Med. Rehabil. 67 (1986), 135-136.
47. J.J. Wyndaele, Urethral sphincter dyssynergia in spinal cord injury patients, Paraplegia 25 (1987), 10-15.
48. A.A. Rodriquez and E. Awad, Detrusor muscle and sphincter response to anorectal stimulation in spinal cord injury, Arch. Phys. Med. Rehabil. 60 (1979), 269-272.
49. R.K. Sethi, S.B. Bauer, F.M. Dyro and C. Krarup, Modulation of the bulbocavernosus reflex during voiding: loss of inhibition in upper motor neuron lesions, Muscle & Nerve 12 (1989), 892-897.
50. J.S. Walter, J.S. Wheeler and R.B. Dunn, Dynamic bulbocavernosus reflex: dyssynergia evaluation following SCI, J. Am. Paraplegia Soc. 17 (1994), 140-145.
51. R.J. Krane and M.B. Siroky, Studies on sacral-evoked potentials, J. Urol. 124 (1980), 872-876.
52. T.G. Hornby, W.Z. Rymer, E.N. Benz and B.D. Schmit, Windup of flexion reflexes in chronic human spinal cord injury: a marker for neuronal plateau potentials? J. Neurophysiol. 89 (2003), 416-426.
53. J.D. van Gool, R.A. Schmidt and E.A. Tanago, Development of reflex activity of detrusor and striated sphincter muscles in experimental paraplegia, Urol. Int. 33 (1978), 293-303.
54. K.B. Thor, J.R. Roppolo and W.C. de Groat, Naloxone induced micturition in unanesthetized paraplegic cats, J. Urol. 129 (1983), 202-205.
55. F.A. Jolesz, C.T. Xu, P.W. Ruenzel and E. Henneman, Flexor reflex control of the external sphincter of the urethra in paraplegia. Science 216 (1982), 1243-1245.
56. F.A. Jolesz, P.W. Ruenzel and E. Henneman, Reflex inhibition of urethral sphincters to permit voiding in paraplegia, Arch. Neurol. 45 (1988), 38-40.
57. W.H. Donovan, D.E. Clowers, M.D. Kiviat and D. Macri, Anal sphincter stretch: a technique to overcome detrusorsphincter dyssynergia, Arch. Phys. Med. Rehabil. 58 (1977), 320-324.
58. M.D. Kiviat, T.A. Zimmermann and W.H. Donovan, Sphincter stretch: a new technique resulting in continence and complete voiding in paraplegics, J. Urol. 114 (1975), 895-897.
59. B.M. Gans, T.A. Zimmerman and W.C. Stolov, Urinary catheterization in severe sphincter spasticity: report of two cases, Arch. Phys. Med. Rehabil. 56 (1975), 498.
60. R.J. Braigrie, J.P Kelleher, D.P. Fawcett and A.W. Pengelly, Oxybutynin: is it safe? Br. J. Urol. 62 (1988), 319-322.
61. C.R. Chapple, Muscarinic receptor antagonists in the treatment of overactive bladder, Urology 55 (2000), 33-46.
62. M. Stohrer, G. Kramer, M. Goepel, D. Lochner-Ernst, D. Kruse and H. Rubben, Bladder autoaugmentation in adult patients with neurogenic voiding dysfunction, Spinal Cord 35 (1997), 456-462.
63. H.D. Flood, S.J. Malhotra, H.E. O'Connell, M.J. Ritchey, D.A. Bloom and E.J. McGuire, Long-term results and complications using augmentation cystoplasty in reconstructive urology, Neurourol. Urodynam. 14 (1995), 297-309.
64. P. Mast, P. Hoebeke, J.J. Wyndaele, W. Oosterlinck and K. Everaert, Experience with augmentation cystoplasty: a review, Paraplegia 33 (1995), 560-564.
65. G.S. Brindley, The first 500 sacral anterior root stimulator implants: general description, Paraplegia 32 (1994), 795-805.
66. M.B. Chancellor and W.C. de Groat, Intravesical capsaicin and resiniferatoxin therapy: spicing up the ways to treat the overactive bladder, J. Urol. 162 (1999), 3-11.
67. M. de Seze, L. Wiart, J. Ferriere, M.P. de Seze, P. Joseph and M. Barat, Intravesical instillation of capsaicin in urology: a review of the literature, Eur. Urol. 36 (1999), 267-277.
68. M. Nakamura and T. Sakurai, Bladder inhibition by penile electrical stimulation, Br. J. Urol. 56 (1984), 413-415.
69. B. Ohlsson, S. Lindstrom, B.E. Erlandson and M. Fall, Effects of some different pulse parameters on bladder inhibition and urethral closure during intravaginal electrical stimulation: an experimental study in the cat, Med. & Biol. Eng. & Comput. 24 (1986), 27-33.
70. T. Sundin, C.A. Carlsson and N.G. Kock, Detrusor inhibition induced from mechanical stimulation of the anal region and from electrical stimulation of pudendal nerve afferents: an experimental study in cats, Invest. Urol. 11 (1974), 374-378.
71. J.S. Walter, J.A. Wheeler, C.J. Robinson and R.D. Wurster, Inhibiting the hyperreflexic bladder with electrical stimulation in a spinal animal model, Neurourol. Urodynam. 13 (1993), 241-253.
72. B.L. Ohlsson, M. Fall and S. Frankenberg-Sommar, Effects of external and direct pudendal nerve maximal electrical stimulation in the treatment of the uninhibited overactive bladder, Br. J. Urol. 64 (1989), 374-380.
73. J.G. Previnaire, J.M. Soler and M. Perrigot, Is there a place for pudendal nerve maximal electrical stimulation for the treatment of detrusor hyperreflexia in spinal cord injury patients? Spinal Cord 36 (1998), 100-103.
74. S. Jezernik, W.M. Grill and T. Sinkjaer, Detection and inhibition of hyperreflexia-like bladder contractions in the cat by sacral nerve root recording and electrical stimulation, Neurourol. Urodynam. 20 (2001), 215-230.
75. G.E. Loeb, R.A. Peck, W.H. Moore and K. Hood, BION system for distributed neural prosthetic interfaces, Med. Eng. & Phys. 23 (2001), 9-18.
76. W.C. de Groat, I. Araki, M.A. Vizzard, M. Yoshiyama, N. Yoshimura, K. Sugaya, C. Tai and J.R. Roppolo, Developmental and injury induced plasticity in the micturition reflex pathway, Behavioural Brain Res. 92 (1998), 127-140.
77. W.C. de Groat, Mechanism underlying the recovery of lower urinary tract function following spinal cord injury, Paraplegia 33 (1995), 493-505.
78. W.C. de Groat, M. Kawatani, T. Hisamitsu, C. Cheng, C. Ma, K. Thor, W. Steers and J.R. Roppolo, Mechanisms underlying the recovery of urinary bladder function following spinal cord injury, J. Auton. Nerv. Syst. 30(suppl.) (1990), s71-s77.
79. W.C. de Groat, I. Nadelhaft, R.J. Milne, A.M. Booth, C. Morgan and K. Thor, Organization of the sacral parasympathetic reflex pathways to the urinary bladder and large intestine, J. Anton. Nerv. Syst. 3 (1981), 135-160.
80. C.J. Fowler, R.O. Beck, S. Gerard, C.D. Betts, C.G. Fowler, Intravesical capsaicin for treatment of detrusor hyperreflexia, J. Neurol. Neurosurg. Psychiatry 57 (1994), 169-173.
81. C.J. Fowler, D. Jewkes, W.I. McDonald, B. Lynn and de W.C. Groat, Intravesical capsaicin for neurogenic bladder dysfunction, Lancet 339 (1992), 1239.
82. A. Catz, Z.P. Luttwak, E. Agranov, J. Ronen, R. Shpaser, A. Paz, D. Lask, A. Tamir and E. Mukamel, The role of external sphincterotomy for patients with spinal cord lesion, Spinal Cord 35 (1997), 48-52.
83. H. Petit, L. Wiart, E. Gaujard, F. Le Breton, J.M. Ferriere, A. Lagueny, P.A. Joseph and M. Barat, Botulinum A toxin treatment for detrusor-sphincter dyssynergia in spinal cord disease, Spinal Cord 36 (1998), 91-94.
84. M.B. Chancellor, D.A. Rivas, C.K. Abdill, S. Karasick, S.M. Ehrlich and W.E. Staas, Prospective comparison of external sphincter balloon dilatation and prosthesis placement with external sphincterotomy in spinal cord injured men, Arch. Phys. Med. Rehab. 75 (1994), 297-305.
85. F.J. Juan Garcia, S. Salvador, A. Montoto, S. Loin, B. Balvis, A. Rodriguez, M. Fernandez and J. Sanchez, Intraurethral stent prosthesis in spinal cord injured patients with sphincter dyssynergia, Spinal Cord 37 (1999), 54-57.
86. J.M. Vapnek, D.R. Couillard and A.R. Stone, Is sphincterotomy the best management of the spinal cord injured bladder? J. Urol. 151 (1994), 961-964.
87. C.C. Yang and M.E. Mayo, External urethral sphincterotomy: long-term follow up, Neurourol. Urodynam. 14 (1995), 25-31.
88. S.J. Tsai, H.L. Lew, E. Date and L.I. Bih, Treatment of detrusor-sphincter dyssynergia by pudendal nerve block in patient with spinal cord injury, Arch. Phys. Med. Rehabil. 83 (2002), 714-717.
89. H.Y. Ko and K.T. Kim, Treatment of external urethral sphincter hypertonicity by pudendal nerve block using phenol solution in patients with spinal cord injury, Spinal Cord 35 (1997), 690-693.
90. M. Ishigooka, T. Hashimoto, I. Sasagawa, K. Izumiya and T. Nakada, Modulation of the urethral pressure by high-frequency block stimulation in dogs, Eur. Urol. 25 (1994), 334-337.
91. J.D. Sweeney, J.T. Mortimer and D.R. Bodner, Acute animal studies of electrically induced collision block of pudendal nerve motor activity, Neurourol. Urodynam. 8 (1989), 521-536.
92. C. van den Honert and J.T. Mortimer, A technique for collision block of peripheral nerve: single stimulus analysis, IEEE Trans. Biomed. Eng. 28 (1981), 373-378.
93. C. van den Honert and J.T. Mortimer, A technique for collision block of peripheral nerve: frequency dependence, IEEE Trans. Biomed. Eng. 28 (1981), 379-382.
94. C. van den Honert and J.T. Mortimer, Generation of unidirectionally propagated action potentials in a peripheral nerve by brief stimuli, Science 206 (1979), 1311-1312.
95. J.D. Sweeney and J.T. Mortimer, An asymmetric two electrode cuff for generation of unidirectionally propagated action potentials, IEEE Trans. Biomed. Eng. 33 (1986), 541-549.
96. A. Schumacher, S. Bross, J.R. Scheepe, C. Seif, K.P. Junemann and P. Alken, Extradural cold block for selective neurostimulation of the bladder: development of a new technique, J. Urol. 161 (1999), 950-954.
97. R.A. Schmidt, Neural prostheses and bladder control, Eng. Med. Bio. Mag. 2 (1983), 31-36.
98. G.H. Creasey, Electrical stimulation of sacral roots for micturition after spinal cord injury, Spinal Cord Injury 20 (1993), 505-515.
99. P.E.V. Van Kerrebroeck, E.L. Koldewijn, P.F.W.M. Rosier, H. Wijkstra and F.M.J. Debruyne, Results of the treatment of neurogenic bladder dysfunction in spinal cord injury by sacral posterior root rhizotomy and anterior sacral root stimulation, J. Urol. 155 (1996), 1378-1381.
100. G.S. Brindley and D.N. Rushton, Long-term follow-up of patients with sacral anterior root stimulator implants, Paraplegia 28 (1990), 469-475.
101. C. Tai, J.R. Roppolo and W.C. de Groat, Block of external urethral sphincter contraction by high frequency electrical stimulation of pudendal nerve, J. Urol. 172 (2004), 2069-2072.
102. B.F.M. Blok, J.T.P.M. van Maarseveen and G. Holstege, Electrical stimulation of the sacral dorsal gray commissure evokes relaxation of the external urethral sphincter in the cat, Neurosci. Lett. 249 (1998), 68-70.
103. W.M. Grill, N. Bhadra and B. Wang, Bladder and urethral pressures evoked by microstimulation of the sacral spinal cord in cats, Brain Res. 836 (1999), 19-30.
104. R.R. Carter, D.B. McCreery, B.J. Woodford, L.A. Bullara and W.F. Agnew, Micturition control by microstimulation of the sacral spinal cord of the cat: acute studies, IEEE Trans. Rehabil. Eng. 3 (1995), 206-214.
105. B.F.M. Blok, H. de Weerd and G. Holstege, The pontine micturition center projects to sacral cord GABA immunoreactive neurons in the cat, Neurosci. Lett. 233 (1997), 109-112.
106. J.A.M.L. Sie, B.F.M. Blok, H. de Weerd and G. Holstege, Ultrastructural evidence for direct projections from the pontine micturition center to glycine-immunoreactive neurons in the sacral dorsal gray commissure in the cat, J. Comp. Neurol. 429 (2001), 631-637.
107. S.J. Shefchyk, Sacral spinal interneurones and the control of urinary bladder and urethral striated sphincter muscle function, J. Physiol. 533 (2001), 57-63.
108. B. Fedirchuk and S.J. Shefchyk, Effects of electrical stimulation of the thoracic spinal cord on bladder and external urethral sphincter activity in the decerebrate cat, Exp. Brain Res. 84 (1991), 635-642.
109. B. Fedirchuk and S.J. Shefchyk, Membrane potential changes in sphincter motoneurons during micturition in the decerebrate cat, J. Neurosci. 13 (1993), 3090-3094.
110. S.J. Shefchyk, The effects of lumbosacral deafferentation on pontine micturition centre - evoked voiding in the decerebrate cat, Neurosci. Lett. 99 (1989), 175-180.
111. N. Shimoda, K. Takakusaki, O. Nishizawa, S. Tsuchida and S. Mori, The changes in the activity of pudendal motoneurons in relation to reflex micturition evoked in decerebrate cats, Neurosci. Lett. 135 (1992), 175-178.
112. G. Holstege, D. Griffiths, H. de Wall and E. Dalm, Anatomical and physiological observations on supraspinal control of bladder and urethral sphincter muscles in the cat, J. Comp. Neurol. 250 (1986), 449-461.
113. E.J. McGuire, Experimental observations on the integration of bladder and urethral function, Trans. Am. Ass. Genito-Urinary Surgeons 68 (1977), 38-42.
114. G. Rampal and P. Mignard, Organization of the nervous control of urethral sphincter, Pflugers Arch. 353 (1975), 21-31.
115. G.S. Brindley, An implant to empty the bladder or close the urethra, J. Neurol. Neurosurg. Psych. 40 (1977), 358-369.
116. G.S. Brindley, The actions of parasympathetic and sympathetic nerves in human micturition, erection and seminal emission, and their restoration in paraplegic patients by implanted electrical stimulators, Proc. R. Soc. Lond. B235 (1988), 111-120.
117. H.E. van der Aa, H. Hermens, E. Alleman and H. Vorsteveld, Sacral anterior root stimulation for bladder control in patients with a complete lesion of the spinal cord, Acta Neurochir. (Wien) 134 (1995), 88-92.
118. E.A. Tanagho and R.A. Schmidt, Electrical stimulation in the clinical management of the neurogenic bladder, J. Urol. 140 (1988), 1331-1339.
119. D. Jonas and E.A. Tanagho, Studies on the feasibility of urinary bladder evacuation by direct spinal cord stimulation - II. Poststimulus voiding: a way to overcome outflow resistance, Invest. Urol. 13 (1975), 151-153.
120. N. Bhadra, V. Grunewald, G. Creasey and J.T. Mortimer, Selective suppression of sphincter activation during sacral anterior nerve root stimulation, Neurourol. Urodynam. 21 (2002), 55-64.
121. C. Seif, P.M. Braun, S. Bross, J. Scheepe, J. Weib, S. Schumacher, S. Zendler, P. Alken and K.P. Junemann, Selective block of urethral sphincter contraction using a modified Brindley electrode in sacral anterior root stimulation of the dog, Neurourol. Urodynam. 21 (2002), 502-510.
122. N.J.M. Rihkhoff, L.B.P.M. Hendridx, P.E.V. van Kerrebroeck, F.M.J. Debruyne and H. Wijkstra, Selective detrusor activation by electrical stimulation of the human sacral nerve roots, Artificial Organs 21 (1997), 223-226.
123. K.D. Sievert, C.A. Gleason, K.P. Junemann, P. Alken and E.A. Tanagho, Physiologic bladder evacuation with selective sacral root stimulation: sinusoidal signal and organ-specific frequency, Neurourol. Urodynam. 21 (2002), 80-91.
124. H.S. Shaker, L.M. Tu, S. Robin, K. Arabi, M. Hassouna, M. Sawan and M.M. Elhilali, Reduction of bladder outlet resistance by selective sacral root stimulation using high-frequency blockade in dogs: an acute study, J. Urol. 160 (1998), 901-907.
125. A. Reitz, M. Stohrer, G. Kramer, G.D. Popolo, E. Chartier-Kastler, J. Pannek, H. Burgdorfer, K. Gocking, H. Madersbacher, S. Schumacher, R. Richter, J. von Tobel and B. Schurch, European experience of 200 cases treated with botulinum - A toxin injections into the detrusor muscle for urinary incontinence due to neurogenic detrusor overactivity, Europ. Urol. 45 (2004), 510-515.
126. S. Barrick, W.C. de Groat and L.A. Birder, Regulation of chemical and mechanical-evoked ATP release from urinary bladder urothelium by botulinum toxin A, Society for Neuroscience Abstract Viewer 541(5) (2004).
127. M. Khera, G.T. Somogyi, S. Kiss, T.B. Boone and C.P. Smith, Botulinum toxin A inhibits ATP release from bladder urothelium after chronic spinal cord injury, Neurochem. Int. 45 (2004), 987-993.
128. W.C. de Groat, The urothelium in overactive bladder: passive bystander or active participant? Urolog 64(suppl.) (2004), 7-11.
129. J. Morrison, L. Birder, M. Craggs, W.C. de Groat, J. Downie, M. Drake, C. Fowler and K. Thor, Neural control, in: Incontinence, P. Abrams, L. Cardozo, S. Khoury and A. Wein, eds, Jersey: Health Publications, Ltd., 2005, pp. 363-422.