Induction of immunological tolerance by oral, but not intravenous and intraportal, administration of ovalbumin and the difference between young and old mice

Journal of Nutrition, Health and Aging

Volumn 10, Issue 3, 2006, Pages 183-191

  Wakabayashi, Ayako ^a   Utsuyama, M ^b,c   Hosoda, T ^d   Sato, K ^d   Takahashi, H ^a   Hirokawa, K ^b  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^d JAPAN WOMEN'S UNIVERSITY   (Japan)

Author keywords

Aging; Immunological tolerance; Intraportal administration; Intravenous administration; Oral administration; Ovalbumin

Indexed keywords

ALUMINUM POTASSIUM SULFATE; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN M; OVALBUMIN; OVALBUMIN ANTIBODY; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY BLOOD LEVEL; ANTIBODY PRODUCTION; ARTICLE; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; DOSE RESPONSE; DRUG MEGADOSE; HYPERSENSITIVITY REACTION; IMMUNIZATION; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOLOGICAL TOLERANCE; IMMUNOSUPPRESSIVE TREATMENT; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; PORTAL VEIN; PRIORITY JOURNAL;

ANIMALIA;

EID: 33646684071     PISSN: 12797707     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Mowat A.M., Strobel S., Drammond H.E., Ferguson A., Immunological responses to fed protein antigens in mice. I. Reversal of oral tolerance to ovalbumin by cyclophosphamide, Immunology, 1982, 45: 105-113.
2. Weiner H.L., Friedman A., Miller A., et. al., Oral tolerance: immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens, Annu. Rev. Immunol., 1994,12: 809-837.
3. Strobel S., Ferguson A., Immune responses to fed protein antigens in mice. 3. Systemic tolerance or priming is related to age at which antigen is first encountered, Pediatr. Res., 1984, 18: 588-594.
4. Faria A.M., Garcia G., Rios M.J., Michalaros C.L., Vaz N.M., Decrease in susceptibility to oral tolerance induction and occurrence of oral immunization to ovalbumin in 20-38-week-old mice. The effect of interval between oral exposures and rate of antigen intake in the oral immunization, Immunology, 1993, 78: 147-151.
5. Wakabayashi A., Utsuyama M., Hosoda T., Sato K., Hirokawa K., Differential age effect of oral administration of an antigen on antibody response: an induction of tolerance in young mice but enhancement of immune response in old mice, Mech. Ageing Dev., 1999, 109: 191-201.
6. Friedman A., Weiner H.L., Induction of anergy or active suppression following oral tolerance is determined by antigen dosage, Proc. Natl. Acad. Sci. U. S. A., 1994, 91: 6688-6692.
7. Burstein H.J., Abbas A.K., In vivo role of interleukin 4 in T cell tolerance induced by aqueous protein antigen, J. Exp. Med., 1993, 177: 457-463.
8. Romball C.G., Weigle W.O., In vivo induction of tolerance in murine CD4+ cell subsets, J. Exp. Med., 1993, 178: 1637-1644.
9. Qian J., Hashimoto T., Fujiwara H., Hamaoka T., Studies on the induction of tolerance to alloantigens. I. The abrogation of potentials for delayed-type-hypersensitivity response to alloantigens by portal venous inoculation with allogeneic cells, J. Immunol., 1985, 134: 3656-3661.
10. Cuison A., Tasaka K., Chuang C.K., Minai M., Yoshikawa H., Nakajima Y., Schistosome eggs in the portal vein can induce tolerance, Int. J. Parasitol., 1995, 25: 993-998.
11. Ogasawara H., Watari E., Shirai Y., Yokomuro K., Inhibitory effects of portal venous injection of type II collagen in collagen-induced arthritis, Nippon Ika Daigaku Zasshi, 1997, 64: 220-224.
12. Liblau R.S., Tisch R., Shokat K., Yang X., Dumont N., Goodnow C.C., McDevitt H.O., Intravenous injection of soluble antigen induces thymic and peripheral T-cells apoptosis, Proc. Natl. Acad. Sci. U. S. A., 1996, 93: 3031-3036.
13. Nagler-Anderson C., Bober L.A., Robinson M.E., Siskind G.W., Thorbecke G.J., Suppression of type II collagen-induced arthritis by intragastric administration of soluble type II collagen, Proc. Natl. Acad. Sci. U. S. A., 1986, 83: 7443-7446.
14. Myers L.K., Stuart J.M., Seyer J.M., Kang A.H., Identification of an immunosuppressive epitope of type II collagen that confers protection against collagen-induced arthritis, J. Exp. Med., 1989, 170: 1999-2010.
15. Endres R.O., Grey H.M., Antigen recognition by T cells. II. Intravenous administration of native or denatured ovalbumin results in tolerance to both forms of the antigen, J. Immunol., 1980, 125: 1521-1525.
16. Vidard L., Colarusso L.J., Benacerraf B. Specific T-cell tolerance may be preceded by a primary response, Proc. Natl. Acad. Sci. U. S. A., 1994, 91: 5627-5631.
17. Wakabayashi A., Eishi Y., Nakamura K., Development of the immune system in severe combined immunodeficiency mice reconstituted with transferred fetal liver cells, J. Med. Dent. Sci., 1997, 44: 21-29.
18. Koga T., McGhee J.R., Kato H., Kato R., Kiyono H., Fujihashi K., Evidence for early aging in the mucosal Immune system, J. Immunol., 2000, 165: 5352-5359.
19. Zhang Y., Yasumizu R., Sugiura K., et. al., Fate of allogeneic or syngeneic cells in intravenous or portal vein injection: possible explanation for the mechanism of tolerance induction by portal vein injection, Eur. J. Immunol., 1994, 24: 1558-1565.
20. Roland C.R., Mangino M.J., Duffy B.F., Flye M.W., Lymphocyte suppression by Kupffer cells prevents portal venous tolerance induction: a study of macrophage function after intravenous gadolinium, Transplantation, 1993, 55: 1151-1158.
21. Viney J.L., Mowat A.M., O'Malley J.M., Williamson E., Fanger N.A., Expanding dendritic cells in vivo enhances the induction of oral tolerance, J. Immunol., 1998, 160: 5815-5825.
22. Limmer A., Ohl J., Kurts C., et. al., Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance, Nat. Med., 2000, 6: 1348-1354.
23. Bruce M.G., Ferguson A., The influence of intestinal processing on the immunogenicity and molecular size of absorbed, circulating ovalbumin in mice, Immunology, 1986, 59: 295-300.
24. Karlsson M.R., Kahu H., Hanson L.A., Telemo E., Dahlgren U.I., Tolerance and bystander suppression, with involvement of CD25-positive cells, is induced in rats receiving serum from ovalbumin-fed donors, Immunology, 2000, 100: 326-333.