Pathological reactions and recovery of hepatopancreatic digestive cells from the marine snail Littorina littorea following exposure to a polycyclic aromatic hydrocarbon

Marine Environmental Research

Volumn 61, Issue 5, 2006, Pages 457-470

  Lowe, D M ^a   Moore, M N ^a   Readman, J W ^a  

^a PLYMOUTH MARINE LABORATORY   (United Kingdom)

Author keywords

7 Ethoxycoumarin o deethylase; Autophagy; Cellular pathology; Endocytosis; Endoplasmic reticulum; Lysosomal stability; Mollusc; Neutral red retention; Polycyclic aromatic hydrocarbon

Indexed keywords

BIODIVERSITY; BIOLOGICAL ORGANS; BIOMARKERS; CELLS; HEALTH CARE; MAPPING; MEASUREMENT THEORY; PATHOLOGY; REGRESSION ANALYSIS;

7-ETHOXYCOUMARIN-O-DEETHYLASE; AUTOPHAGY; CELLULAR PATHOLOGY; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; LYSOSOMAL STABILITIES; MOLLUSCS; NEUTRAL RED RETENTION;

POLYCYCLIC AROMATIC HYDROCARBONS;

7 ETHOXYCOUMARIN DEETHYLASE; BIOLOGICAL MARKER; FLUORANTHENE; NEUTRAL RED; POLYCYCLIC AROMATIC HYDROCARBON;

BIOMARKER; HEALTH STATUS; MARINE ENVIRONMENT; PAH; PATHOLOGY; SNAIL; STRESS; STUDY PERSPECTIVE; TOXICITY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL HEALTH; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; ENDOCYTOSIS; ENVIRONMENTAL EXPOSURE; HEPATOPANCREAS; LYSOSOME MEMBRANE; MULTIVARIATE ANALYSIS; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; SMOOTH ENDOPLASMIC RETICULUM; SNAIL; UNIVARIATE ANALYSIS;

7-ALKOXYCOUMARIN O-DEALKYLASE; ANIMALS; BIOLOGICAL MARKERS; CELLS, CULTURED; CLUSTER ANALYSIS; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; FLUORENES; HEPATOPANCREAS; LYSOSOMES; NEUTRAL RED; SEAWATER; SNAILS; STATISTICS;

ANIMALIA; GASTROPODA; LITTORINA LITTOREA;

EID: 33646674693     PISSN: 01411136     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.marenvres.2006.01.001     Document Type: Article

References (85)

1. Addison R.F., Hansen P.-D., Pluta H.-J., and Willis D.E. Effects of Ugilic-141, a PCB substitute based on tetrachlorobenzyltoluenes, on hepatic mono-oxygenase induction in estuarine fish. Marine Environmental Research 31 (1991) 137-144
2. Addison R.F., Willis D.E., and Zinck M.E. Liver microsomal mono-oxygenase in winter flounder (Pseudopleuronectes americanus) from a gradient of sediment PAH concentrations at Sydney Harbour, Nova Scotia. Marine Environmental Research 37 (1994) 283-296
3. Allen J.I., and Moore M.N. Environmental prognostics: is the current use of biomarkers appropriate for environmental risk evaluation. Marine Environmental Research 58 (2004) 227-232
4. Allison A.C., and Young M.R. Vital staining and fluorescence microscopy of lysosomes. In: Dingle J.T., and Fell H.B. (Eds). Lysosomes in biology and pathology (1969), Elsevier, Amsterdam, Oxford, New York 600-628
5. Astley K.N., Meigh H.C., Glegg G.A., Braven J., and Depledge M.H. Multi-variate analysis of biomarker responses in Mytilus edulis and Carcinus maenas from the Tees Estuary (UK). Marine Pollution Bulletin 39 (1999) 145-154
6. Bayne B.L., Brown D.W., Burns K., Dixon D.R., Ivanovici A., Livingstone D.R., et al. The Effects of Stress and Pollution on Marine Animals (1985), Praeger, New York, Philadelphia, Eastbourne U.K., Toronto (p. 384)
7. Bayne B.L., Holland D.L., Moore M.N., Lowe D.M., and Widdows J. Further studies on the effects of stress in the adult on the eggs of Mytilus edulis. Journal of the Marine Biological Association of the United Kingdom 58 (1978) 825-841
8. Bayne B.L., Moore M.N., Widdows J., Livingstone D.R., and Salkeld P.N. Measurement of the responses of individuals to environmental stress and pollution: studies with bivalve molluscs. Philosophical Transactions of the Royal Society of London 286B (1979) 563-581
9. Brion D., and Pelletier E. Modelling PAHs adsorption and sequestration in freshwater and marine sediments. Chemosphere 61 (2005) 867-876
10. Brunk U.T., and Terman A. Lipofuscin: mechanisms of age-related accumulation and influence on cell function. Free Radical Biology and Medicine 33 (2002) 611-619
11. Cajaraville M.P., Bebianno M.J., Blasco J., Porte C., Sarasquete C., and Viarengo A. The use of biomarkers to assess thew impact of pollution in coastal environments of the Iberian peninsula: a practical approach. Science of the Total Environment 247 (2000) 295-311
12. Cajaraville M.P., Abascal I., Etxeberria M., and Marigómez I. Lysosomes as cellular markers of environmental pollution: time- and dose-dependant responses of the digestive lysosomal system of mussels after petroleum hydrocarbon exposure. Environmental Toxicology and Water Quality 10 (1995) 1-8
13. Chatfield C., and Collins A.J. Introduction to multivariate analysis (1980), Chapman and Hall, London
14. Clarke K.R. Non-metric multivariate analysis in community-level ecotoxicology. Environmental Toxicology and Chemistry 18 (1999) 117-127
15. Dailianis S., Domouhtsidou G.P., Raftopoulou E., Kaloyianni M., and Dimitriadis V.K. Evaluation of neutral red retention assay, micronucleus test, acetylcholinesterase activity and a signal transduction molecule (cAMP) in tissues of Mytilus galloprovincialis (L.), in pollution monitoring. Marine Environmental Research 56 (2003) 443-470
16. Dauberschmidt C., Dietrich D.R., and Schlatter C. Investigations on the biotransformation capacity of organophosphates in the mollusc Dreissena polymorpha P. Aquatic Toxicology 37 (1997) 283-294
17. De Duve C., Barsy T., Poole B., Touret A., Tulkens P., and van Hoof F. Lysosomotropic agents. Biochemical Pharmacology 23 (1974) 2495-2531
18. De Matteis F., Dawson S.J., Pons N., and Pipino S. Bilirubin and uroporphyrinogen oxidation by induced cytochrome P450 1A and cytochrome P450 2B: role of polyhalogenated biphenyls of different configurations. Biochemical Pharmacology 63 (2002) 615-624
19. Depledge M.H., Amaral-Mendes J.J., Daniel B., Halbrook R.S., Kloepper-Sams P., Moore M.N., et al. The conceptual basis of the biomarker approach. In: Peakall D.G., and Shugart L.R. (Eds). Biomarkers - research and application in the assessment of environmental health (1993), Springer-Verlag, Berlin, Heidelberg 15-29
20. Domouhtsidou G.P., and Dimitriadis V.K. Lysosomal and lipid alterations in the digestive gland of mussels as biomarkers of environmental stress, Mytilus galloprovincialis (L.). Environmental Pollution 115 (2001) 123-137
21. Donkin P., Widdows J., Evans S.V., Worrall C.M., and Carr M. Quantitative structure-activity relationships for the effect of hydrophobic organic chemicals on rate of feeding by mussels (Mytilus edulis). Aquatic Toxicology 14 (1989) 277-294
22. Galloway T.S., Sanger R.C., Smith K.L., Fillmann G., Readman J.W., Ford T.E., et al. Rapid assessment of marine pollution using multiple biomarkers and chemical immunoassays. Environmental Science & Technology 36 (2002) 2219-2226
23. Galloway T.S., Brown R.J., Browne M.A., Dissanayake A., Lowe D., Jones M.B., et al. A multibiomarker approach to environmental assessment. Environmental Science & Technology 38 (2004) 1723-1731
24. Gould P. Nanoparticles probe biosystems. Materials Today 7 (2004) 36-43
25. Hankard P.K., Svendsen C., Wright J., Wienberg C., Fishwick S.K., Spurgeon D.J., et al. Biological assessment of contaminated land using earthworm biomarkers in support of chemical analysis. Science and Total Environment 330 (2004) 9-20
26. Howard V. Small particles - big problems. International Laboratory News 34 2 (2004) 28-29
27. Hwang H.-M., Wade T.L., and Sericano J.L. Relationship between lysosomal membrane destabilization and chemical body burden in eastern oysters (Crassostre virginica) from Galveston Bay, Texas, USA. Environmental Toxicology and Chemistry 21 (2002) 1268-1271
28. Kalpaxis D.L., Theos C., Xaplanteri M.A., Dinos G.P., Catsiki A.V., and Leotsinidis M. Biomonitoring of Gulf of Patras, N. Peloponnesus, Greece. Application of a biomarker suite including evaluation of translation efficiency in Mytilus galloprovincialis cells. Environmental Research 94 (2004) 211-220
29. Kirchin M.A., Moore M.N., Dean R.T., and Winston G.W. The role of oxyradicals in intracellular proteolysis and toxicity in mussels. Marine Environmental Research 34 (1992) 315-320
30. Klionsky D.J., and Emr S.D. Autophagy as a regulated pathway of cellular degradation. Science 290 (2000) 1717-1721
31. Köhler A., Deisemann H., and Lauritzen B. Ultrastructural and cytochemical indices of toxic injury in dab liver. Marine Ecology-Progress Series 91 (1992) 141-153
32. Köhler A., Wahl E., and Söffker K. Functional and morphological changes of lysosomes as prognostic biomarkers of toxic liver injury in a marine flatfish (Platichthys flesus (L)). Environmental Toxicology and Chemistry 21 (2002) 2434-2444
33. Krishnakumar P.K., Casillas E., and Varanasi U. Effect of environmental contaminants on the health of Mytilus edulis from Puget Sound, Washington, USA.I. Cytochemical measures of lysosomal responses in the digestive cells using automatic image analysis. Marine Ecology-Progress Series 106 (1994) 249-261
34. Lekube X., Cajaraville M.P., and Marigomez I. Use of polyclonal antibodies for the detection of changes induced by cadmium in lysosomes of aquatic organisms. Science of the Total Environment 247 (2000) 201-212
35. Livingstone D.R. Contaminant-stimulated reactive oxygen species production and oxidative damage in aquatic organisms. Marine Pollution Bulletin 42 (2001) 656-666
36. Livingstone D.R., Chipman J.K., Lowe D.M., Minier C., Mitchelmore C.L., Moore M.N., et al. Development of biomarkers to detect the effects of organic pollution on aquatic invertebrates: recent molecular, genotoxic, cellular and immunological studies on the common mussel (Mytilus edulis L.) and other mytilids. International Journal of Environmental Pollution 13 1-6 (2000) 56-91
37. Livingstone D.R., Kirchin M.A., and Wiseman A. Cytochrome P-450 and oxidative metabolism in molluscs. Xenobiotica 19 (1989) 1041-1062
38. Livingstone D.R., Moore M.N., Lowe D.M., Nasci C., and Farrar S.V. Responses of the cytochrome P-450 monooxygenase system to diesel oil in the common mussel, Mytilus edulis L. and the periwinkle Littorina littorea L. Aquatic Toxicology 7 (1985) 79-91
39. Livingstone D.R., Nasci C., Solé M., Da Ros L., O'Hara S.C.M., Peters L.D., et al. Apparent induction of a cytochrome P450 with immunochemical similarities to CYP1A in digestive gland of the common mussel (Mytilus galloprovincialis L.) with exposure to 2,2′,3,4,4′,5′-hexachlorobiphenyl and Arochlor 1254. Aquatic Toxicology 38 (1997) 205-224
40. Lowe D.M. Alterations in cellular structure of Mytilus edulis resulting from exposure to environmental contaminants under field and experimental conditions. Marine Ecology-Progress Series 46 (1988) 91-100
41. Lowe D.M., and Moore M.N. The cytochemical distributions of zinc (ZnII) and iron (FeIII) in the common mussel, Mytilus edulis, and their relationship with lysosomes. Journal of the Marine Biological Association of the United Kingdom 59 (1979) 851-858
42. Lowe D.M., and Pipe R.K. Contaminant induced lysosomal membrane damage in marine mussel digestive cells: an in vitro study. Aquatic Toxicology 30 (1994) 357-365
43. Lowe D.M., Fossato V.U., and Depledge M.H. Contaminant induced lysosomal membrane damage in blood cells of mussels M. galloprovincialis from the Venice Lagoon: an in vitro study. Marine Ecology-Progress Series 129 (1995) 189-196
44. Lowe D.M., Moore M.N., and Clarke K.R. Effects of oil on digestive cells in mussels: quantitative alterations in cellular and lysosomal structure. Aquatic Toxicology 1 (1981) 213-226
45. Lowe D.M., Moore M.N., and Evans B.M. Contaminant impact on interactions of molecular probes with lysosomes in living hepatocytes from dab Limanda limanda. Marine Ecology-Progress Series 91 (1992) 135-140
46. Lowe D.M., Soverchia C., and Moore M.N. Lysosomal membrane responses in mussels to experimental contaminant exposure. Aquatic Toxicology 33 (1995) 105-112
47. Moore M.N., Allen J.I., and McVeigh. Environmental prognostics: An integrated model supporting lysosomal stress responses as predictive biomarkers of animal health status. Marine Environmental Research 61 (2006) 278-304
48. Marigomez I., and Baybay-Villacorta L. Pollutant-specific and general lysosomal responses in digestive cells of mussels exposed to model organic chemicals. Aquatic Toxicology 64 (2003) 235-257
49. Moore M.N. Cytochemical demonstration of latency of lysosomal hydrolases in digestive cells of the common mussel, Mytilus edulis and changes induced by thermal stress. Cell Tissue Research 175 (1976) 279-287
50. Moore M.N. Cytochemical responses of the lysosomal system and NADPH-ferrihemoprotein reductase in molluscs to environmental and experimental exposure to xenobiotics. Marine Ecology-Progress Series 46 (1988) 81-89
51. Moore M.N. Cellular responses to pollutants. Marine Pollution Bulletin 16 (1985) 134-139
52. Moore M.N. Lysosomal cytochemistry in marine environmental monitoring. Histochemical Journal 22 (1990) 187-191
53. Moore M.N. Molecular cell pathology of pollutant induced liver injury in flatfish: use of fluorescent probes. Marine Ecology-Progress Series 91 (1992) 127-133
54. Moore M.N. Biocomplexity: the post-genome challenge in ecotoxicology. Aquatic Toxicology 59 (2002) 1-15
55. Moore M.N., and Halton D.W. Cytochemical localization of lysosomal hydrolases in the digestive cells of littorinids and changes induced by larval trematode infection. Zeitschrift fur Parasitenkunde 53 (1977) 115-122
56. Moore M.N., Bubel A., and Lowe D.M. Cytology and cytochemistry of the pericardial gland cells of Mytilus edulis and their lysosomal responses to injected horseradish peroxidase and anthracene. Journal of the Marine Biological Association of the United Kingdom 60 (1980) 135-149
57. Moore M.N., Depledge M.H., Readman J.W., and Leonard D.R.P. An integrated biomarker-based strategy for ecotoxicological evaluation of risk in environmental management. Mutation Research 552 (2004) 247-268
58. Moore M.N., Köhler A., Lowe D.M., and Simpson M.G. An integrated approach to cellular biomarkers in fish. In: Fossi M.C., and Leonzio C. (Eds). Non-destructive biomarkers in vertebrates (1994), Lewis/CRC, Boca Raton 171-197
59. Moore M.N., Lowe D.M., Soverchia C., Haigh S.D., and Hales S.G. Uptake of a non-calorific, edible sucrose polyester oil and olive oil by marine mussels and their influence on uptake and effects of anthracene. Aquatic Toxicology 39 (1997) 307-320
60. Moore M.N., Mayernick J.A., and Giam C.S. Lysosomal responses to a polynuclear aromatic hydrocarbon in a marine snail: effects of exposure to phenanthrene and recovery. Marine Environmental Research 17 (1985) 230-233
61. Moore M.N., Pipe R.K., and Farrar S.V. Lysosomal and microsomal responses to environmental factors in Littorina littorea from Sullom Voe. Marine Pollution Bulletin 13 (1982) 340-345
62. Moore M.N., Pipe R.K., Farrar S.V., Thomson S., and Donkin P. Lysosomal and microsomal responses to oil-derived hydrocarbons in Littorina littorea. In: Capuzzo J.M., and Kester D.R. (Eds). Oceanic processes in marine pollution - biological processes and waste in the ocean Vol. 1 (1986), Krieger Publishing, Melbourne (Florida) 89-96
63. Moore M.N., Soverchia C., and Thomas M. Enhanced lysosomal autophagy of intracellular proteins by xenobiotics in living molluscan blood cells. Acta Histochemica et Cytochemica 29 Supplement (1996) 947-948
64. Nott J.A., and Moore M.N. Effects of polycyclic aromatic hydrocarbons on molluscan lysosomes and endoplasmic reticulum. Histochemical Journal 19 (1987) 357-368
65. Owen G. The fine structure of the digestive tubules of the marine bivalve Cardium edule. Philosophical Transactions of the Royal Society of London 258B (1970) 245-260
66. Panyam J., and Labhasetwar V. Biodegradable nanoparticles for drug and gene delivery to cells and tissues. Advanced Drug Delivery Review 55 (2003) 329-347
67. Peek K., and Gabbot P.A. Adipogranular cells from the mantle tissue of Mytilus edulis L. 1. Isolation, purification and biochemical characteristics of dispersed cells. Journal of Experimental Marine Ecology 126 (1989) 203-216
68. Pipe R.K., and Moore M.N. Arylsulphatase activity associated with phenanthrene induced digestive cell deletion in the marine mussel Mytilus edulis. Histochemical Journal 18 (1986) 557-564
69. Pipe R.K., and Moore M.N. An ultrastructural study on the effects of phenanthrene on lysosomal membranes and distribution of the lysosomal membranes and distribution of the lysosomal enzyme b-glucuronidase in digestive cells of the periwinkle Littorina littorea. Aquatic Toxicology 8 (1986) 65-76
70. Rashid F., Horobin R.W., and Williams M.A. Predicting the behaviour and selectivity of fluorescent probes for lysosomes and related structures by means of structure-activity models. Histochemial Journal 23 (1991) 450-459
71. Readman J.W., Mantoura R.F.C., Rhead M.M., and Brown L. Aquatic distribution and microbial heterotrophic degradation of polycyclic aromatic hydrocarbons (PAH) in the Tamar Estuary. Estuarine and Coastal Shelf Science 14 (1982) 369-389
72. Regoli F. Total oxyradical scavenging capacity (TOSC) in polluted and translocated mussels: a predictive biomarker of oxidative stress. Aquatic Toxicology 50 (2000) 351-361
73. Ringwood A.H., Hoguet J., Keppler C., and Gielazyn M. Linkages between cellular biomarker responses and reproductive success in oysters, Crassostrea virginica. Mar Environmental Research 58 (2004) 151-155
74. Shaw J.P., Large A.T., Donkin P., Evans S.V., Staff F.J., Livingstone D.R., et al. Seasonal variation in cytochrome P450 immunopositive protein levels, lipid peroxidation and genetic toxicity in digestive gland of the mussel Mytilus edulis. Aquatic Toxicology 67 (2004) 325-336
75. Shaw J.P., Peters L.D., and Chipman J.K. CYP1A- and CYP3A-immunopositive protein levels in digestive gland of the mussel Mytilus galloprovincialis from the Mediterranean Sea. Marine Environmental Research 58 (2004) 649-653
76. Sole' S., and Livingstone D.R. Components of the cytochrome P450-dependent monooxygenase system and 'NADPH-independent benzo[a]pyrene hydroxylase' activity in a wide range of marine invertebrate species. Comparative Biochemistry and Physiology C141 (2005) 20-31
77. Svendsen C., and Weeks J.M. The use of a lysosome assay for the rapid assessment of cellular stress from copper to the freshwater snail Viviparus contectus (Millet). Marine Pollution Bulletin 31 (1995) 139-142
78. Viarengo A., Moore M.N., Pertica M., Mancinelli G., and Accomando R. A simple procedure for evaluating the protein degradation rate in mussel (Mytilus galloprovincialis Lam.) tissues and its application in a study of phenanthrene effects on protein catabolism. Comparative Biochemistry and Physiology 103B (1992) 27-32
79. Wedderburn J., Cheung V., Bamber S., Bloxham M., and Depledge M.H. Biomarkers of histochemical and cellular stress in Carcinus maenas: an in situ field study. Marine Environmental Research 46 (1998) 321-324
80. White I.N.H. A continuous fluorimetric assay for cytochrome P450 - dependant mixed function oxidase activity using 3-cyano-7-ethoxycoumarin. Analytical Biochemistry 172 (1988) 304-310
81. Widdows J., Bakke T., Bayne B.L., Donkin P., Livingstone D.R., Lowe D.M., et al. Responses of Mytilus edulis L. on exposure to the water accommodated fraction of North Sea oil. Marine Biology 67 (1982) 15-31
82. Winston G.W., Adams S.M., Benson W.H., Gray L.E., Matthews H.S., Moore M.N., et al. Biological bases of similarities and differences. In: Di Giulio R.T., and Benson W.B. (Eds). Interconnections between human health and ecological integrity (2002), Society of Environmental Toxicology and Chemistry (SETAC), Pensacola, Florida 43-65
83. Winston G.W., Moore M.N., Kirchin M.A., and Soverchia C. Production of reactive oxygen species (ROS) by hemocytes from the marine mussel, Mytilus edulis. Comparative Biochemistry and Physiology 113C (1996) 221-229
84. Winston G.W., Moore M.N., Straatsburg I., and Kirchin M. Lysosomal stability in Mytilus edulis L.: potential as a biomarker of oxidative stress related to environmental contamination. Archives of Environmental Contamination and Toxicology 21 (1991) 401-408
85. Yawetz A., Mandelis R., and Fishelson L. The effect of arochlor 1254 and petrochemical pollutants on cytochrome P-450 from the digestive gland microsomes of four species of Mediterranean molluscs. Comparative Biochemistry and Physiology C103 (1992) 607-614