Natural killer cells prime the responsiveness of autologous CD4+ T cells to CTLA4-Ig and interleukin-10 mediated inhibition in an allogeneic dendritic cell-mixed lymphocyte reaction

Immunology

Volumn 118, Issue 2, 2006, Pages 216-223

  Newland, Ashley ^a,b   Russ, Graeme ^a,b   Krishnan, Ravi ^a,b  

^a QUEEN ELIZABETH HOSPITAL   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Costimulation; Cytotoxic T lymphocyte antigen 4; Dendritic cells; Interleukin 10; Mixed lymphocyte reaction; Natural killer cells

Indexed keywords

ABATACEPT; B7 ANTIGEN; CD28 ANTIGEN; CD4 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; CD86 ANTIGEN; INTERLEUKIN 10; MONOCLONAL ANTIBODY CD3; NYLON;

ALLOIMMUNITY; ARTICLE; CD4+ T LYMPHOCYTE; CELL CULTURE; CELL INTERACTION; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CULTURE MEDIUM; CYTOLYSIS; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNOMODULATION; INNATE IMMUNITY; MIXED LYMPHOCYTE REACTION; NATURAL KILLER CELL; NORMAL HUMAN; PRIORITY JOURNAL; UPREGULATION; WOOL;

ANTIGENS, CD80; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL COMMUNICATION; CELL PROLIFERATION; COCULTURE TECHNIQUES; DENDRITIC CELLS; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; HUMANS; IMMUNE TOLERANCE; IMMUNOCONJUGATES; INTERLEUKIN-10; KILLER CELLS, NATURAL; LYMPHOCYTE CULTURE TEST, MIXED; UP-REGULATION;

EID: 33646595995     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2006.02359.x     Document Type: Article

References (32)

1. Banchereau J Steinman RM Dendritic cells and the control of immunity Nature 1998 392 245 52
2. Lu LMD Starzl TE Thomson AW Bone marrow-derived dendritic cell progenitors (NLDC 145+, MHC class II+, B7-1dim, B7-2-) induce alloantigen-specific hyporesponsiveness in murine T lymphocytes Transplantation 1995 60 1539 45
3. Fu F Li Y Qian S Lu L Chambers F Starzl TE Fung JJ Thomson AW Costimulatory molecule-deficient dendritic cell progenitors (MHC class II+, CD80dim, CD86-) prolong cardiac allograft survival in nonimmunosuppressed recipients Transplantation 1996 62 659 65
4. Rastellini CLL Ricordi C Rao AS Thomson AW Granulocyte/macrophage colony-stimulating factor-stimulated hepatic dendritic cell progenitors prolong pancreatic islet allograft survival Transplantation 1995 60 1366 70
5. De Smedt T Van Mechelen M De Becker G Urbain J Leo O Moser M Effect of interleukin-10 on dendritic cell maturation and function Eur J Immunol 1997 27 1229 35
6. Caux C Massacrier C Vanbervliet B Barthelemy C Liu YJ Banchereau J Interleukin 10 inhibits T cell alloreaction induced by human dendritic cells Int Immunol 1994 6 1177 85
7. Shurin MR Yurkovetsky ZR Tourkova IL Balkir L Shurin GV Inhibition of CD40 expression and CD40-mediated dendritic cell function by tumor-derived IL-10 Int J Cancer 2002 101 61 8
8. Buelens C Willems F Delvaux A Pierard G Delville JP Velu T Goldman M Interleukin-10 differentially regulates B7-1 (CD80) and B7-2 (CD86) expression on human peripheral blood dendritic cells Eur J Immunol 1995 25 2668 72
9. Coates PT Krishnan R Kireta S Johnston J Russ GR Human myeloid dendritic cells transduced with an adenoviral interleukin-10 gene construct inhibit human skin graft rejection in humanized NOD-scid chimeric mice Gene Ther 2001 8 1224 33
10. Linsley PS Brady W Urnes M Grosmaire LS Damle NK Ledbetter JA CTLA-4 is a second receptor for the B cell activation antigen B7 J Exp Med 1991 174 561 9
11. van der Merwe PA Bodian DL Daenke S Linsley P Davis SJ CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics J Exp Med 1997 185 393 403
12. Hathcock KS Laszlo G Pucillo C Linsley P Hodes RJ Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function J Exp Med 1994 180 631 40
13. Newland A Kireta S Russ G Krishnan R Ovine dendritic cells transduced with an adenoviral CTLA4eEGFP fusion protein construct induce hyporesponsiveness to allostimulation Immunology 2004 113 310 7
14. Sayegh MH Zheng XG Magee C Hancock WW Turka LA Donor antigen is necessary for the prevention of chronic rejection in CTLA4Ig-treated murine cardiac allograft recipients Transplantation 1997 64 1646 50
15. Lin H Bolling SF Linsley PS Wei RQ Gordon D Thompson CB Turka LA Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion J Exp Med 1993 178 1801 6
16. O'Rourke RW Kang SM Lower JA Feng S Ascher NL Baekkeskov S Stock PG A dendritic cell line genetically modified to express CTLA4-IG as a means to prolong islet allograft survival Transplantation 2000 69 1440 6
17. Kirk AD Harlan DM Armstrong NN et al. CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates Proc Natl Acad Sci USA 1997 94 8789 94
18. Bonham CA Peng L Liang X et al. Marked prolongation of cardiac allograft survival by dendritic cells genetically engineered with NF-kappa B oligodeoxyribonucleotide decoys and adenoviral vectors encoding CTLA4-Ig J Immunol 2002 169 3382 91
19. Takayama T Nishioka Y Lu L Lotze MT Tahara H Thomson AW Retroviral delivery of viral interleukin-10 into myeloid dendritic cells markedly inhibits their allostimulatory activity and promotes the induction of T-cell hyporesponsiveness Transplantation 1998 66 1567 74
20. Akdis CA Joss A Akdis M Faith A Blaser K A molecular basis for T cell suppression by IL-10: CD28-associated IL-10 receptor inhibits CD28 tyrosine phosphorylation and phosphatidylinositol 3-kinase binding FASEB J 2000 14 1666 8
21. Hanna J Fitchett J Rowe T et al. Proteomic analysis of human natural killer cells: insights on new potential NK immune functions Mol Immunol 2005 42 425 31
22. Zingoni A Sornasse T Cocks BG Tanaka Y Santoni A Lanier LL Cross-talk between activated human NK cells and CD4+ T cells via OX40-OX40 ligand interactions J Immunol 2004 173 3716 24
23. Assarsson E Kambayashi T Schatzle JD Cramer SO von Bonin A Jensen PE Ljunggren HG Chambers BJ NK cells stimulate proliferation of T and NK cells through 2B4/CD48 interactions J Immunol 2004 173 174 80
24. Fernandez NC Lozier A Flament C et al. Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo Nat Med 1999 5 405 11
25. Gerosa F Gobbi A Zorzi P Burg S Briere F Carra G Trinchieri G The reciprocal interaction of NK cells with plasmacytoid or myeloid dendritic cells profoundly affects innate resistance functions J Immunol 2005 174 727 34
26. Wilson JL Heffler LC Charo J Scheynius A Bejarano MT Ljunggren HG Targeting of human dendritic cells by autologous NK cells J Immunol 1999 163 6365 70
27. Piccioli D Sbrana S Melandri E Valiante NM Contact-dependent stimulation and inhibition of dendritic cells by natural killer cells J Exp Med 2002 195 335 41
28. Biron C Nguyen KB Pien GC Cousens LP Salazar-Mather T Natural killer cells in antiviral defence: function and regulation by innate cytokines Annu Rev Immunol 1997 17 189 220
29. Robertson MJ Ritz J Biology and clinical relevance of human natural killer cells Blood 1990 76 2421 38
30. Uehara S Chase CM Colvin RB Russell PS Madsen JC Further evidence that NK cells may contribute to the development of cardiac allograft vasculopathy Transplant Proc 2005 37 70 1
31. Maier S Tertilt C Chambron N Gerauer K Huser N Heidecke CD Pfeffer K Inhibition of natural killer cells results in acceptance of cardiac allografts in CD28-/- mice Nat Med 2001 7 557 62
32. Westerhuis G Maas WG Willemze R Toes RE Fibbe WE Long-term mixed chimerism after immunological conditioning and MHC-mismatched stem cell transplantation is dependent on NK cell tolerance Blood 2005 106 2215 20