Impact of physical activity during pregnancy and postpartum on chronic disease risk

Medicine and Science in Sports and Exercise

Volumn 38, Issue 5, 2006, Pages 989-1006

  Pivarnik, James M ^a   Chambliss, Heather O ^a   Clapp, James F ^a   Dugan, Sheila A ^a   Hatch, Maureen C ^a   Lovelady, Cheryl A ^a   Mottola, Michelle F ^a   Williams, Michelle A ^a  

^a NONE

Author keywords

Diabetes; Exercise; Hypertension; Obesity; Women

Indexed keywords

BREAST FEEDING; CHILD DEVELOPMENT; CHILD HEALTH; CHRONIC DISEASE; EVIDENCE BASED MEDICINE; HUMAN; MATERNAL HYPERTENSION; MENTAL HEALTH; MUSCULOSKELETAL DISEASE; OBESITY; ORGANIZATION; PHYSICAL ACTIVITY; PRACTICE GUIDELINE; PREECLAMPSIA; PREGNANCY; PREGNANCY DIABETES MELLITUS; PUERPERIUM; REVIEW; RISK REDUCTION; SAFETY; WEIGHT REDUCTION;

ADOLESCENT; ADULT; BREAST FEEDING; CHILD; CHILD WELFARE; CHRONIC DISEASE; CONGRESSES; DIABETES, GESTATIONAL; EVIDENCE-BASED MEDICINE; EXERCISE; FEMALE; HUMANS; HYPERTENSION; MENTAL HEALTH; MICHIGAN; MUSCULOSKELETAL DISEASES; OBESITY; POSTPARTUM PERIOD; PRE-ECLAMPSIA; PREGNANCY; RISK ASSESSMENT; WEIGHT LOSS;

EID: 33646534840     PISSN: 01959131     EISSN: None     Source Type: Journal    
DOI: 10.1249/01.mss.0000218147.51025.8a     Document Type: Review

References (182)

1. ABRAHAM, S., A. TAYLOR, and J. CONTI. Postnatal depression, eating, exercise, and vomiting before and during pregnancy. Int. J. Eat. Disord. 29:482-487, 2001.
2. ALESSIO, H. M., and E. R. BLASI. Physical activity as a natural antioxidant booster and its effects on a healthy life span. Res. Q. Exerc. Sport. 68:292-302, 1997.
3. AMAGADA, J. O., L. JOELS, and S. CATLING. Stress fracture of rib in pregnancy: what analgesic? J. Obstet. Gynaecol. 22:559, 2002.
4. AMERICAN COLLEGE OF OBSTETRICIANS AND GYNECOLOGISTS (ACOG). Technical Bulletin: Exercise During Pregnancy and the Postnatal Period. Washington DC: ACOG; 1985.
5. AMERICAN COLLEGE OF OBSTETRICIANS AND GYNECOLOGISTS Gestational Diabetes. ACOG Practice Bulletin 30:525-538, 2001.
6. AMERICAN COLLEGE OF OBSTETRICIANS AND GYNECOLOGISTS Exercise during pregnancy and the postpartum period. ACOG Committee Opinion 267. Obstet. Gynecol. 99:171-173, 2002.
7. AMERICAN DIABETES ASSOCIATION. 2004 Gestational diabetes mellitus. Diabetes Care 27:888-90, 2004.
8. ARMSTRONG, K., and H. EDWARDS. The effects of exercise and social support on mothers reporting depressive symptoms: a pilot randomized controlled trial. Int. J. Mental Health Nurs. 12:130-138, 2003.
9. ARTAL, R. Exercise: the alternative therapeutic intervention for gestational diabetes. Clin. Obstet. Gynecol. 46:479-487, 2003.
10. AVERY, M. D., A. S. LEON, and R. A. KOPHER. Effects of a partially home-based exercise program for females with gestational diabetes. Obstet. Gynecol. 89:10-15, 1997.
11. AVERY, M. D., and A. J. WALKER. Acute effect of exercise on blood glucose and insulin levels in women with gestational diabetes. J. Maternal-Fetal Med. 10:52-58, 2001.
12. BARKER, D. J. P. Fetal Origins of Cardiovascular and Lung Disease, New York: National Institutes of Health; 2000.
13. BATADA, A., M. F. MOTTOLA, C. BRUN, et al. Effects of a Nutrition, Exercise and Lifestyle Intervention Program (NELIP) women at risk for gestational diabetes (GDM). Can. J. Appl. Physiol. 28(Suppl):S29, 2003.
14. BEN-HAROUSH, A., Y. YOGEV, and M. HOD. Epidemiology of gestational diabetes and its association with Type 2 diabetes. Diabetic Med. 21:103-113, 2003.
15. BERGMANN, A., M. ZYOMUNT, and J. F. CLAPP. Running throughout pregnancy: effect on placental villous vascular volume and cell proliferation. Placenta 25:694-698, 2004.
16. BLECHER, A. M., and J. C. RICHMOND. Transient laxity of an anterior cruciate ligament-reconstructed knee related to pregnancy. Arthroscopy 14:77-79, 1998.
17. BLUMENTHAL, J. A., M. A. BABYAK, K. A. MOORE, et al. Effects of exercise training on older patients with major depression. Arch. Intern. Med. 159:2349-2356, 1999.
18. BOISSONNAULT, J. S., and M. J. BLASCHAK. Incidence of diastasis recti abdominis during the childbearing year. Phys. Ther. 68:1082-1086, 1988.
19. BOPP, M. J., C. A. LOVELADY, C. P. HUNTER, and T. C. KINSELLA. Maternal diet and exercise: effects on long-chain polyunsatu-rated fatty acid concentrations in breast milk. J. Amer. Diet. Assoc. 105:1098-1103, 2005.
20. BRANKSTON, G., B. MITCHELL, E. RYAN, and N. OKUN. Resistance exercise decreases the need for insulin in overweight women with gestational diabetes mellitus. Am J. Obstet. Gynecol. 190:188-193, 2004.
21. BRITES, F. D., P. A. EVELSON, M. G. CHRISTIANSEN, et al. Soccer players under regular training show stress by an improved plasma antioxidant status. Clin. Sci. 96:381-385, 1999.
22. BROOCKS, A., B. BANDELOW, G. PEKRUN, et al. Comparison of aerobic exercise, clomipramine, and placebo in the treatment of panic disorder. Am. J. Psychiatry 155:603-639, 1998.
23. BROWN, J. S., L. M. NYBERG, J. W. KUSEK, et al. National Institute of Diabetes and Digestive Kidney Diseases International Research Working Group on Bladder Dysfunction. Proceedings of the National Institute of Diabetes and Digestive and Kidney Diseases International Symposium on Epidemiologic Issues in Urinary Incontinence in Women. Am. J. Obstet. Gynecol. 188:877-888, 2003.
24. BRYNHILDSEN, J., A. HANSSON, A. PERSSON, and M. HAMMAR. Follow-up of patients with low back pain during pregnancy. Obstet. Gynecol. 91:182-186, 1998.
25. BUNG, P., C. BUNG, R. ARTAL, N. KHODOGIUAN, F. FALLENSTEIN, and L. SPATLING. Therapeutic exercise for insulin-requiring GDM. Results from a randomized prospective longitudinal study. J. Perinat. Med. 21:125-137, 1993.
26. BURGIO, K. L., H. ZYCZYNSKI, J. L. LOCHER, H. E. RICHTER, D. T. REDDEN, and K. C. WRIGHT. Urinary incontinence in the 12-month postpartum period. Obstet. Gynecol. 102:1291-1298, 2003.
27. BUTLER, C. L., M. A. WILLIAMS, T. K. SORENSEN, I. O. FREDERICK, and W. M. LEISENRING. Relationship between maternal recreational physical activity and plasma lipids in early pregnancy. Am. J. Epidemiol. 160:350-359, 2004.
28. CANADIAN DIABETES ASSOCIATION CLINICAL PRACTICE GUIDELINES EXPERT COMMITTEE. Clinical practice guidelines for the prevention and management of diabetes in Canada. Can. J. Diabetes 27 (suppl. 2):S99-S105, 2003.
29. CAPPIELLO, G. A., and B. C. OLIVER. Rupture of the symphysis pubis caused by forceful and excessive abduction of the thighs with labor epidural anesthesia. J. Fla. Med. Assoc. 82:261-263, 1995.
30. CATALANO, P., A. THOMAS, L. HUSTON-PRESLEY, and S. AMINI. Increased fetal adiposity: a very sensitive marker of abnormal in utero development. Am. J. Obstet. Gynecol. 189:1689-1704, 2003.
31. CHROUSOS, G. P., D. J. TORPY, and P. W. GOLD. Interactions between the hypothalamic-pituitary-adrenal axis and the female reproductive system: clinical implications. Ann. Int. Med. 129:229-240, 1998.
32. CLAPP, J. F. III. The course of labor after endurance exercise during pregnancy. Am. J. Obstet. Gynecol. 163:1799-1805, 1990.
33. CLAPP, J. F. A clinical approach to exercise during pregnancy. Clin. Sports Med. 13:443-458, 1994.
34. CLAPP, J. F. Exercise during pregnancy. In: Perspectives in Exercise Science and Sports Medicine: Exercise and the Female-a Life Span Approach, O. Bar-Or, D. Lamb, and P. Clarkson. Carmel, IN: Cooper Publishing Group, 1996, pp. 413-451.
35. CLAPP, J. F. Morphometric and neurodevelopmental outcome at five years of the offspring of women who continued to exercise throughout pregnancy. J. Pediatr. 129:856-863, 1996.
36. CLAPP, J. F. Exercise during pregnancy-a clinical update. Clin. Sportsmed. 19:273-286, 2000.
37. CLAPP, J. F. Exercising Through Your Pregnancy, Omaha, NE: Addicus Books; 2002.
38. CLAPP, J. F. Maternal carbohydrate intake and pregnancy outcome. Proc. Nutr. Soc. 61:45-50, 2002.
39. CLAPP, J. F. The effects of maternal exercise on fetal oxygenation and feto-placental growth. Eur. J. Obstet. Gynecol. Reprod. Biol. 110:S80-S85, 2003.
40. CLAPP, J. F. III, and W. KIESS. Effects of pregnancy and exercise on concentrations of the metabolic markers tumor necrosis factor α and leptin. Am. J. Obstet. Gynecol. 182:300-306, 2000.
41. CLAPP, J. F., H. KIM, B. BURCIU, and B. LOPEZ. Beginning regular exercise in early pregnancy: effect on feto-placental growth. Am. J. Obstet. Gynecol. 183:1484-1488, 2000.
42. CLAPP, J. F., H. KIM, B. BURCIU, S. SCHMIDT, K. PETRY, and B. LOPEZ. Continuing regular exercise during pregnancy: effect of exercise volume on feto-placental growth. Am. J. Obstet. Gynecol. 189:142-147, 2002.
43. CLAPP, J. F. III, and K. D. LITTLE. Effect of recreational exercise on pregnancy weight gain and subcutaneous fat deposition. Med. Sci. Sports Exerc. 27:170-177, 1995.
44. CLAPP, J. F., K. D. LITTLE, S. A. APPLEBY-WINEBERG, and J. A. WIDNESS. The effect of regular exercise in late pregnancy on erythropoietin levels in amniotic fluid and cord blood. Am. J. Obstet. Cynecol. 172:1445-1451, 1995.
45. CLAPP, J. F., B. LOPEZ, and R. HARCAR-SEVCIK. The neonatal behavioral profile of the offspring of women who continued to exercise regularly throughout pregnancy. Am. J. Obstet. Gynecol. 180:91-94, 1999.
46. CLAPP, J. F., S. SIMONEAN, B. LOPEZ, S. APPLEBY-WINEBERG, and R. HARCAR-SECIK. One year morphometric and neurodevelopmental outcome of the offspring of women who continued to exercise regularly throughout pregnancy. Am. J. Obstet. Gynecol. 178:594-599, 1998.
47. CLEMETSON, I. A., A. POPP, K. LIPPUNER, et al. Postpartum osteoporosis associated with proximal tibial stress fracture. Skeletal Radiol. 33:96-98, 2004.
48. CONSIDINE, R. V. Invited editorial on "Acute and chronic effects of exercise on leptin levels in humans". J. Appl. Physiol. 83:3-4, 1997.
49. CURRIE, J. L., and E. DEVELIN. Stroll your way to well-being: a survey of the perceived benefits, barriers, community support, and stigma associated with pram walking groups. Health Care Women Int. 23(8):882-893, 2002.
50. DACOSTA, D., N. RIPPEN, M. DRITSA, and A. RING. Self-reported leisure-time physical activity during pregnancy and relationship to psychological well-being. J. Psychosom. Obstet. Gynaecol. 24:111-119, 2003.
51. DAVENPORT, M. H., H. YAKUBCHUK, R. MCMANUS, and M. F. MOTTOLA. The need for an alternative lifestyle treatment for Gestational Diabetes. Can. J. Appl. Physiol. In Press. (Abstract).
52. DAVIES, G. A., L. A. WOLFE, M. F. MOTTOLA, et al. Joint SOGC/CSEP clinical practice guideline: exercise in pregnancy and the postpartum period. Can. J. Appl. Physiol. 28:330-341, 2003.
53. DEMPSEY, J., C. BUTLER, T. SORENSEN, et al. A case-control study of maternal recreational physical activity and risk of gestational diabetes mellitus. Diabetes Res. Clin. Pract. 66:203-215, 2004.
54. DEMPSEY, J. C., T. K. SORENSEN, M. A. WILLIAMS, et al. Prospective study of gestational diabetes mellitus risk in relation to maternal recreational physical activity before and during pregnancy. Am. J. Epidemiol. 159:663-670, 2004.
55. DEWEY, K. G., C. A. LOVELADY, L. A. NOMMSEN-RIVERS, M. A. MCCRORY, and B. LONNERDAL. A randomized study of the effects of aerobic exercise by lactating women on breast-milk volume and composition. N. Engl. J. Med. 330:449-453, 1994.
56. DISHMAN, R. K. Physical activity and mental health. In: Encyclopedia of Mental Health, Vol. 3, H. S. Friedman. San Diego, CA: Academic Press, 1998, pp. 171-188.
57. DONAHUE, R. P., P. ZIMMET, J. A. BEAN, et al. Cigarette smoking, alcohol use, and physical activity in relation to serum leptin levels in a multiethnic population: the Miami Community Health Study. Ann. Epidemiol. 9:108-113, 1999.
58. DORNHORST, A., and M. ROSSI. Risk and prevention of type 2 diabetes in women with gestational diabetes. Diabetes Care 21:B43-B49, 1998.
59. DUNN, A. L., M. H. TRIVEDI, J. B. KAMPERT, C. G. CLARK, and H. O. CHAMBLISS. Exercise treatment for depression: efficacy and dose response. Am. J. Prev. Med. 28:1-8, 2005.
60. DUNN, A. L., M. TRIVEDI, and H. A. O'NEAL. Physical activity dose-response effects on outcomes of depression and anxiety. Med. Sci. Sports Exerc. 33:S587-S597, 2001.
61. DURSTINE, J. L., P. W. GRANDJEAN, P. G. DAVIS, M. A. FERGUSON, N. L. ALDERSON, and K. D. DUBOSE. Blood lipid and lipoprotein adaptations to exercise: a quantitative analysis. Sports Med. 31:1033-1062, 2001.
62. DYCK, R., H. KLOMP, L. TAN, R. TURNELL, and M. BOCTOR. A comparison of rates, risk factors, and outcomes of gestational diabetes between aboriginal and non-aboriginal women in the Saskatoon health district. Diabetes Care 25:487-493, 2002.
63. DYE, T. D., K. L. KNOX, R. ARTAL, R. H. AUBRY, and M. A. WOJTOWYCZ. Physical activity, obesity, and diabetes in pregnancy. Am. J. Epidemiol. 146:961-965, 1997.
64. EKMAN-ORDEBERG, G., S. SALGEBACK, and G. ORDEBERG. Carpal tunnel syndrome in pregnancy. A prospective study. Acta Obstet. Gynec. Scand. 66:233-235, 1987.
65. ENQUOBAHRIE, D. A., M. A. WILLIAMS, C. BUTLER, I. O. FREDERICK, R. S. MILLER, and D. A. LUTHY. Maternal plasma lipid concentrations in early pregnancy and risk of preeclampsia. Am. J. Hypertens. 17:574-558, 2004.
66. FAST, A., D. SHAPIRO, E. J. DUCOMMUN, L. W. FRIEDMANN, T. BOUKLAS, and Y. FLOMAN. Low-back pain in pregnancy. Spine 2:368-371, 1987.
67. FLIK, K., D. ANDERSON, W. URNEY, et al. Locked knee during pregnancy. Anhroscopy 20:191-195, 2004.
68. FRANKS, P. W., S. FAROOQI, J. LUAN, et al. Does physical activity energy expenditure explain the between-individual variation in plasma concentrations after adjusting for differences in body composition? J. Clin. Endocrinol. Metab. 88:3258-3263, 2003.
69. cp rat. Horm. Metab. Res. 29:214-219, 1997.
70. GARCIA-PATTERSON, A., E. MARTIN, J. UBEDA, M. MARIA, A. DELEIVA, and R. CORCOY. 2001. Evaluation of light exercise in the treatment of Gestational Diabetes. Diabetes Care 24:2006-2007, 2001.
71. GOLDMAN, M., J. KITXMILLER, B. ABRAMS, R. COWAN, and R. LAROS. Obstetric complications with GDM: effects of maternal weight. Diabetes 40(S2):79-82, 1991.
72. GONIK, B., and C. A. STRINGER. Postpartum osteitis pubis. South Med. J. 78:213-214, 1985.
73. GOODWIN, A., J. ASTBURY, and J. MCMEEKEN. Body image and psychological well-being in pregnancy. A comparison of exercisers and non-exercisers. Aust. N. Z. J. Obstet. Gynaecol. 40:442-447, 2000.
74. GREGORY, R. L., J. P. WALLACE, L. E. GFELL, J. MARKS, and B. A. KING. Effect of exercise on milk immunoglobulin A. Med. Sci. Sports. Exerc. 29:1596-1601, 1997.
75. GUNDERSON, E. P. Intensive nutrition therapy for GDM. Diabetes Care 20:221-226, 1997.
76. GUNDERSON, E. P., B. ABRAMS, and S. SELVIN. The relative importance of gestational gain and maternal characteristics associated with the risk of becoming overweight after pregnancy. Int. J. Obes. 24:1660-1668, 2000.
77. HALL, D. C., and D. A. KAUFMANN. Effects of aerobic and strength conditioning on pregnancy outcomes. Am. J. Obstet. Gynecol. 157:1199-1203, 1987.
78. HARRIS, S. B., L. CAULFIELD, M. SUGAMORI, E. WHELAN, and B. HENNING. The epidemiology of diabetes in pregnant Native Canadians. A risk profile. Diabetes Care 20:1422-1425, 1997.
79. HARVEY, M. A. Pelvic floor exercises during and after pregnancy: a systematic review of their role in preventing pelvic floor dysfunction. J. Obstet Gynaecol. Canada 25:487-498, 2003.
80. HATOUM, N., J. F. CLAPP, M. R. NEUMAN, N. DEJANI, and S. B. AMINI. Effects of maternal exercise on fetal activity late in gestation. J. Matern-Fetal Med. 6:134-139, 1997.
81. HE, J., and L. A. BAZZANO. Effects of lifestyle modification on treatment and prevention of hypertension. Curr. Opinion Nephrol. Hypertens. 9:267-271, 2000.
82. HECKMAN, J. D., and R. SASSARD. Current concepts review. Musculoskeletal considerations in pregnancy. J. Bone Joint Surg. Am. 76-A:1720-1730, 1994.
83. HORNS, P. N., L. P. RATCLIFFE, J. C. LEGGETT, and M. S. SWANSON. Pregnancy outcomes among active and sedentary primiparous women. J. Obstet. Gynecol. Neonatal Nurs. 25:49-54, 1996.
84. JOHNSON, C. A. Occurrence of DeQuervain's disease in post-partum women. J. Fam. Prac. 32:325-327, 1991.
85. JOVANOVIC, L. What is so bad about a big baby? Diabetes Care 24:317-318, 2001.
86. JOVANOVIC-PETERSON, L., E. P. DURAK, and C. M. PETERSON. Randomized trial of diet vs. diet plus cardiovascular conditioning on glucose levels in gestational diabetes. Am. J. Obstet. Gynecol. 161:415-419, 1989.
87. KAAJA, R., M. J. TIKKANEN, L. VINNIKKA, and O. YLIKORKALA. Serum lipoproteins, insulin, and urinary prostanoid metabolites in normal and hypertensive pregnant women. Obstet. Gynecol. 85:353-356, 1995.
88. KELLY, C., and G. BOOTH. Diabetes in Canadian Women. BMC Women's Health 4:S16-S24, 2004.
89. KELLY, G. A. Aerobic exercise and resting blood pressure among women: a meta-analysis. Preven. Med. 28:264-275, 1999.
90. KIHLSTRAND, M., B. STENMAN, S. NILSSON, and O. AXELSSON. Water-gymnastics reduced the intensity of back/low back pain in pregnant women. Acta Obstet. Gynecol. Scand. 78:180-185, 1999.
91. KONIAK-GRIFFIN, D. Aerobic exercise, psychological well-being, and physical discomforts during adolescent pregnancy. Res. Nurs. Health 17:253-263, 1994.
92. KOSAKI, A., K. YAMADA, and H. KUZUYA. Reduced expression of the leptin gene (ob) by catecholamine through a G(S) protein pathway in 3T3-L1 adipocytes. Diabetes 45:1744-1749, 1996.
93. KRISTIANSSON, P., K. SVARDSUDD, and B. VON SCHOULTZ. Back pain during pregnancy: a prospective study. Spine 21:702-709, 1996.
94. KUBITZ, R. L., and R. C. GOODLIN. Symptomatic separation of the pubic symphysis. South Med. J. 79:578-580, 1986.
95. KURKI, T., V. HILESMAA, R. RAITASALO, H. MATTILA, and O. YLIKORKALA. Depression and anxiety in early pregnancy and risk of preeclampsia. Obstet. Gynecol. 95:487-490, 2000.
96. LESSER, K. B., P. A. GRUPPUSO, R. B. TERRY, and M. W. CARPENTER. Exercise fails to improve postprandial glycemic excursion in females with Gestational Diabetes. J. Matern. Fetal. Med. 5:211-217, 1996.
97. LINDEBERG, S., O. AXELSSON, U. JORNER, L. MALMBERG, and B. SANSTROM. A prospective controlled five-year follow-up study of primiparas with gestational hypertension. Acta Obstet. Gynecol. Scand. 67:605-609, 1988.
98. LINDGREN, K. Relationships among maternal-fetal attachment, prenatal depression, and health practices in pregnancy. Res. Nurs. Health 24:203-217, 2001.
99. LINNE, Y. Effects of obesity on women's reproduction and complications during pregnancy. Obesity Rev. 5:137-143, 2004.
100. LOVELADY, C. A., K. E. GARNER, K. L. MORENO, and J. P. WILLIAMS. The effect of weight loss in overweight, lactating women on the growth of their infants. N. Engl. J. Med. 342:449-453, 2000.
101. LOVELADY, C. A., C. P. HUNTER, and C. GEIGERMAN. Effect of exercise on immunological factors in breast milk. Pediatrics 111:e148-e152, 2003.
102. LOVELADY, C. A., B. LONNERDAL, and K. G. DEWEY. Lactation performance of exercising women. Am. J. Clin. Nutr. 52:103-109, 1990.
103. LOVELADY, C. A., L. A. NOMMSEN-RIVERS, M. A. MCCRORY, and K. G. DEWEY. Effects of exercise on plasma lipids and metabolism of lactating women. Med. Sci. Sports Exerc. 27:22-28, 1995.
104. LOVELADY, C. A., J. P. WILLIAMS, K. E. GARNER, K. L. MORENO, M. L. TAYLOR, and J. E. LEKLEM. Effect of energy restriction and exercise on vitamin B-6 status of women during lactation. Med. Sci. Sports Exerc. 33:512-518, 2001.
105. MAIESE, D. R. Healthy people 2010-leading health indicators for women. Womens Health Issues 12:155-164, 2002.
106. MARCOUX, S., J. BRISSON, and J. FABIA. The effect of leisure time physical activity on the risk of preeclampsia and gestational hypertension. J. Epidemiol. Community Health 43:147-152, 1989.
107. MARQUEZ-STERLING, S., A. C. PERRY, T. A. KAPLAN, R. A. HALBERSTEIN, and J. F. SIGNORILE. Physical and psychological changes with vigorous exercise in sedentary primigravidae. Med. Sci. Sports Exerc. 32:58-62, 2000.
108. MAYER-DAVIS, E. J., R. D'AGOSTINO Jr., A. J. KARTER, et al. Intensity and amount of physical activity in relation to insulin sensitivity, the Insulin Resistance Atherosclerosis Study. JAMA 279:669-674, 1998.
109. MCCRORY, M. A., L. A. NOMMSEN-RIVERS, P. A. MOLE, B. LONNERDAL, and K.G. DEWEY. A randomized trial of the short-term effects of dieting vs dieting with aerobic exercise on lactation performance. Am. J. Clin. Nutr. 69:959-967, 1999.
110. MCMURRAY, R. G., M. F. MOTTOLA, L. A. WOLFE, R. ARTAL, L. MILLAR, and J. M. PIVARNIK. Recent advances in understanding maternal and fetal responses to exercise. Med. Sci. Sports Exerc. 25:1305-1321, 1993.
111. MILLER, L. J. Postpartum depression. JAMA 287:762-765, 2002.
112. MORKVED, S., K. BO, B. SCHEI, and K. A. SALVESEN. Pelvic floor muscle training during pregnancy to prevent urinary incontinence: a single blind randomized controlled trial. Obstet. Gynecol. 101:313-319, 2003.
113. MOTTOLA, M. F., J. M. S. HAMMOND, R. MCMANUS, C. LEBRUN, and N. LEWIS. Effects of a controlled nutrition and mild exercise program on glucose metabolism in healthy pregnant women. Can. J. Appl. Physiol. 24:468, 1999.
114. MOTTOLA, M. F., S. LANDER, I. GIROUX, et al. Glucose and insulin responses in women at risk for GDM before and after a Nutrition, Exercise and Lifestyle Intervention Program (NELIP). Med. Sci. Sports Exerc. 37(Suppl):S309-S310, 2005, (abstract).
115. MOTTOLA, M. F., M. M. SOPPER, D. VANDERSPANK, S. CHARLESWORTH, and A. HANLEY. Insulin sensitivity is maintained in late pregnancy among overweight women at risk for gestational diabetes participating in a Nutrition and Exercise Lifestyle Intervention Program (NELIP). Can. Federation Biological Societies Proceedings: 62. 2005
116. MOTTOLA, M. F., C. A. WEIS, I. M. S. HAMMOND, et al. Effects of mild vs moderate exercise training on GLUT4. Can. J. Appl. Physiol. 23:496, 1998.
117. MOTTOLA, M. F., C. WEIS, N. LEWIS, et al. Effects of mild vs. moderate maternal exercise on glucose metabolism. Med. Sci. Sports Exerc. 30(Suppl.):S259, 1998, (abstract).
118. MURRAY, C. J., and A. D. LOPEZ. Regional patterns of disability-free life expectancy and disability-adjusted life expectancy: global burden of disease study. Lancet 349:1347-1352, 1997.
119. NACHUM, Z., I. BEN-SHOLOMOK, E. WEINER, and E. SHALEV. Twice daily versus four times daily insulin dose regimens for diabetes in pregnancy: randomised controlled trial. Brit. Med. J. 319:1223-1227, 1999.
120. NARENDRAN, S., R. NAGARATHNA, V. NARENDRAN, S. GUNASHEELA, and H. R. R. NAGENDRA. Efficacy of yoga on pregnancy outcome. J. Alt. Comp. Med. 11:237-244, 2005.
121. NATIONAL FEDERATION OF STATE HIGH SCHOOL ASSOCIATIONS. Athletics Participation Totals. Available at http://www.nfhs. org/Participation/ SportsPart01.htm, 2001.
122. National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy: Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy. Am. J. Obstet. Gynecol. 183:S1-S22, 2000.
123. NING, Y., M. A. WILLIAMS, I. C. DEMPSEY, T. K. SORENSEN, I. O. FREDERICK, and D. A. LUTHY. Correlates of recreational physical activity in early pregnancy. J. Matern. Fetal Neonatal Med. 13:385-393, 2003.
124. NING, Y., M. A. WILLIAMS, M. MUY-RIVERA, W. M. LEISENRING, and D. A. LUTHY. Relationship of maternal plasma leptin and risk of preeclampsia: a prospective study. J. Matern. Fetal Neonatal Med. 15:186-192, 2004.
125. NISELL, H., H. LINTU, N. O. LUNELL, G. MOLLERSTROM, and E. PETTERSSON. Blood pressure and renal function seven years after pregnancy complicated by hypertension. Br. J. Obstet. Gynaecol. 102:876-881, 1995.
126. NORDHAGEN, I. H., and J. SUNDGOT-BORGEN. Physical activity among pregnant women in relation to pregnancy-related complaints and score of depression (Norwegian). Tidsskr. Nor Laegeforen 122:470-474, 2002.
127. NOREN, L., S. OSTGAARD, G. JOHANSSON, and H. C. OSTGAARD. Lumbar back and posterior pelvic pain during pregnancy: a 3-year follow-up. Eur. Spine J. 11:267-271, 2002.
128. OSTGAARD, H. C., and G. B. ANDERSSON. Previous back pain and risk of developing back pain in a future pregnancy. Spine 16:432-436, 1991.
129. OSTGAARD, H. C., G. B. ANDERSSON, and K. KARLSSON. Prevalence of back pain in pregnancy. Spine 16:549-552, 1991.
130. OSTGAARD, H. C., G. ZETHERSTROM, and E. ROOS-HANSSON. Back pain in relation to pregnancy: a 6-year follow-up. Spine 22:2945-2950, 1997.
131. OWENS, K., A. PEARSON, and G. MASON. Symphysis pubis dysfunction-a cause of significant obstetric morbidity. Eur. J. Obstet. Gynecol. Reprod. Biol. 105:143-146, 2002.
132. POTTER, J. M., and P. J. NESTEL. The hyperlipidemia of pregnancy in normal and complicated pregnancies. Am. J. Obstet. Gynecol. 133:165-171, 1979.
133. POUDEVIGNE, M. S., and P. J. O'CONNOR. Physical activity and mood during pregnancy. Med. Sci. Sports Exerc. 37:1374-1380, 2005.
134. QIU, C., D. A. LUTHY, C. ZHANG, S. W. WALSH, W. M. LEISENRING, and M. A. WILLIAMS. A prospective study of maternal serum C-reactive protein concentrations and risk of preeclampsia. Am. J. Hypertens. 17:154-160, 2004.
135. RACETTE, S. B., S. W. COPPACK, M. LANDT, and S. KLEIN. Leptin production during moderate-intensity aerobic exercise. J. Clin. Endocrinol. Metab. 82:2275-2277, 1997.
136. RITCHIE, J. R. Orthopedic considerations during pregnancy. Clin. Obstet. Gynecol. 46:456-466, 2003.
137. ROBERTSON, W. B., T. Y. KHONG, I. BROSENS, F. D. WOLF, B. L. SHEPPARD, and J. BONNER. The placental bed biopsy: review from three European centers. Am. J. Obstet. Gynecol. 155:401-412, 1986.
138. RODRIGUES, S., E. ROBINSON, and K. GRAY-DONALD. Prevalence of gestational diabetes mellitus among James Bay Cree women in northern Quebec. Can. Med. Assoc. J. 160:1293-1297, 1999.
139. RODNEY, B. L., and C. W. SCHAUBERGER. Excess pregnancy weight gain and long-term obesity: one decade later. Obstet. Gynecol. 100:245-252, 2002.
140. RUIGE, J. B., J. M. DEKKER, W. F. BLUM, et al. Leptin and variables of body adiposity, energy balance, and insulin resistance in a population-based study. The Hoorn Study. Diabetes Care 22:1097-1104, 1999.
141. SACHECK, J. M., E. A. DECKER, and P. M. CLARKSON. The effect of diet on vitamin E intake and oxidative stress in response to acute exercise in female athletes. Eur. J. Appl. Physiol. 83:40-46, 2000.
142. SANDERSON, P. L., and R. D. FRASER. The influence of pregnancy on the development of degenerative spondylolisthesis. J. Bone Joint Surg. (Br) 78:951-954, 1996.
143. SAFTLAS, A. E, N. LOGSDEN-SACKETT, W. WANG, R. WOOLSON, and M. B. BELACKEN. Work, leisure-time physical activity, and risk of preeclampsia and gestational hypertension. Am. J. Epidemiol. 160:758-765, 2004.
144. SARIKAYA, S., S. OZDOLAP, G. ACIKGOZ, et al. Pregnancy-associated osteoporosis with vertebral fractures and scoliosis. Joint, Bone, Spine: Revue du Rhumatisme 71:84-85, 2004.
145. SCHMID, L., C. PFIRRMANN, T. HESS, et al. Bilateral fracture of the sacrum associated with pregnancy: a case report. Osteoporos. Int. 10:91-93, 1999.
146. SCHNED, E. S. DeQuervain's tenosynovitis in pregnant and postpartum women. Obstet. Gynecol. 68:411-414, 1986.
147. SCHOBEL, H. P., T. FISCHER, K. HEUSZER, H. GEIGER, and R. E. SCHMIEDER. Preeclampsia-a state of sympathetic overactivity. N. Engl. J. Med. 335:1480-1485, 1996.
148. 2- adrenergic receptors. Eur. J. Endocrinol. 143:439-445, 2000.
149. SHUMACHER, H. R. Jr., B. B. DORWART, and O. M. KORZENIOWSKI. Occurrence of DeQuervain's tendonitis during pregnancy. Arch. Intern. Med. 145:2083-2084, 1985.
150. SIBAI, B. M., A. EL-NAZER, and A. GONZALEZ-RUE. Severe preeclampsia-eclampsia in young primigravid women: subsequent pregnancy outcome and remote prognosis. Am. J. Obstet. Gynecol. 155:1011-1016, 1986.
151. SOLOMON, C. G., W. C. WILLETT, V. J. CAREY, et al. A prospective study of pregravid determinants of gestational diabetes mellitus. JAMA 278:1078-1083, 1997.
152. SOPPER, M. M, J. HAMMOND, I. GIROUX, R. MCMANUS, and M. F. MOTTOLA. Genesis of NELIP: A Nutrition, Exercise and Lifestyle Intervention Program to help prevent excess weight gain and GDM in high-risk women. Can. J. Diabetes 28:296, 2004.
153. SORENSEN, T. K., M. R. MALINOW, M. A. WILLIAMS, I. B. KING, and D. A. LUTHY. Elevated second trimester serum homocyst(e)ine levels and subsequent risk of preeclampsia. Gynecol. Obstet. Invest. 48:98-103, 1999.
154. SORENSEN, T. K., M. A. WILLIAMS, I.-M. LEE, E. E. DASHOW, M. L. THOMPSON, and D. A. LUTHY. Recreational physical activity during pregnancy and risk of preeclampsia. Hypertension 41:1273-1280, 2003.
155. STAPLETON, D. B., A. H. MACLENNAN, and P. KRISTIANSSON. The prevalence of recalled low back pain during and after pregnancy: a South Australian population survey. Aust. N. Z. J. Obstet. Gynaecol. 42:482-485, 2002.
156. STOLP-SMITH, K. A., M. K. PASCOE, and P. L. OGBURN. Carpal tunnel syndrome in pregnancy: frequency, severity and prognosis. Arch. Phys. Med. Rehabil. 79:1285-1287, 1998.
157. STUGE, B., E. LAERUM, G. KIRKESOLA, and N. VOLLESTAD. The efficacy of a treatment program focusing on specific stabilizing exercises for pelvic girdle pain after pregnancy. A randomized controlled trial. Spine 29:351-359, 2004.
158. SYMONS-DOWNS, D., and H. A. HAUSENBLAS. Women's exercise beliefs and behaviors during their pregnancy and postpartum. J. Midwifery Womens Health 49:138-144, 2004.
159. THIENPONT, E., J. P. SIMON, and G. FABRY. Sacral stress fracture during pregnancy-a case report. Acta Orthop. Scand. 70:525-526, 1999.
160. To, W. W., and M. W. WONG. Factors associated with back pain symptoms in pregnancy and the persistence of pain 2 years after pregnancy. Acta Obstet. Gynecol. Scand. 82:1086-1091, 2003.
161. TRAYHURN, P., J. S. DUNCAN, N. HOGGARD, and D. V. RAYNER. Regulation of leptin production: a dominant role for the sympathetic nervous system? Proc. Nutr. Soc. 57:413-419, 1998.
162. TURGUT, F., M. TURGUT, and M. CETINSAHIN. A prospective study of persistent back pain after pregnancy. Eur. J. Obstet. Gynecol. Reprod. Biol. 80:45-18, 1998.
163. VOITK, A. J., J. C. MUELLER, D. E. FARLINGER, et al. Carpal tunnel syndrome in pregnancy. Canadian Med. Assn. J. 128:277-281, 1983.
164. VULLO, V. J., J. K. RICHARDSON, and E. A. HURVITZ. Hip, knee and foot pain during pregnancy and the postpartum period. J. Fam. Pract. 43:63-68, 1996.
165. WALKER, J. J. Preeclampsia. Lancet 356:1260-1265, 2000.
166. WALLACE, A. M., D. B. BOYER, A. DAN, and K. HOLM. Aerobic exercise, maternal self-esteem, and physical discomforts during pregnancy. J. Nurse Midwifery 31:255-262, 1986.
167. WALSH, S. W. Lipid peroxidation in pregnancy. Hypertens in Pregnancy 13:32-41, 199.
168. WALSH, S. W., J. B. MICHAEL, and N. H. ALLEN. Placental prostacyclin production in normal and toxemic pregnancies. Am. J. Obstet. Gynecol. 151:110-115, 1985.
169. WAND, J. S. Carpal tunnel syndrome in pregnancy and lactation. J. Hand Surg. Br. 15:93-95, 1990.
170. WILLIAMS, M. A., A. FARRAND, R. MITTENDORF, et al. Maternal second-trimester serum tumor necrosis factor-α soluble receptor p55 (sTNFp55) and subsequent risk of preeclampsia. Am. J. Epidemiol. 149:323-329, 1999.
171. WILLIAMS, M. A., P. J. HAVEL, M. W. SCHWARTZ, et al. Preeclampsia disrupts the normal relationship between serum leptin concentrations and adiposity in pregnant women. Paediatr. and Perinatal Epidemiol. 13:190-204, 1999.
172. WILLIAMS, M. A., and R. MITTENDORF. Maternal morbidity. In: Women and Health, M. B. Goldman and M. Hatch. Academic Press Inc, 2000, pp. 172-181.
173. WILLIAMSON, D. F., J. MADANS, E. PAMUK, K. M. FLEGAL, J. S. KENDRICK, and M. K. SERDULA. A prospective study of childbearing and 10-year weight gain in US white women 25 to 45 years of age. Int. J. Obes. Relat. Metab. Disord. 18:561-569, 1994.
174. WISNER, K. L., B. L. PARRY, and C. M. PIONTEK. Postpartum depression. N. Engl. J. Med. 347:194-199, 2002.
175. WOLFE, L. A., and M. F. MOTTOLA. PARmed-X for pregnancy, Ottawa, Ont. Canada: Canadian Society for Exercise Physiology, 2002, pp. 1-4.
176. WOLFE, L. A., P. J. OHTAKE, M. F. MOTTOLA, and M. J. MCGRATH. Physiological interactions between pregnancy and aerobic exercise. Exerc. Sport Sci. Rev. 17:295-351, 1989.
177. WOLFE, W. S., J. SOBAL, C. M. OLSON, E. A. FRONGILLO, and D. F. WILLIAMSON. Parity-associated weight gain and its modification by sociodemographic and behavioral factors: a prospective analysis in US women. Int. J. Obes. 21:802-810, 1997.
178. WONG, C. A., B. M. SCAVONE, S. DUGAN, et al. Incidence of postpartum lumbosacral spine and lower extremity nerve injuries. Obstet. Gynecol. 101:279-288, 2003.
179. WRIGHT, K. S., T. J. QUINN, and G. B. CAREY. Infant acceptance of breast milk after maternal exercise. Pediatrics 109:585-589, 2002.
180. YEO, S., N. M. STEELE, M. C. CHANG, S. M. LECLAIRE, D. L. RONIS, and R. HAYASHI. Effect of exercise on blood pressure in pregnant women with a high risk of gestational hypertensive disorders. J. Reprod. Med. 45:293-298, 2000.
181. YOGEV, Y., E. XENAKIS, and O. LANGER. The association between preeclampsia and the severity of gestational diabetes: the impact of glycemic control. Amer. J. Obstet. Gynecol. 191:1655-1660, 2004.
182. ZHANG, C., M. A. WILLIAMS, I. B. KING, et al. Dietary intake and plasma vitamin C status in relation to preeclampsia risk. Epidemiology 13:409-416, 2002.