-
1
-
-
84958689411
-
The role of depot fat in the hypothalamic control of food intake in the rat
-
Kennedy GC: The role of depot fat in the hypothalamic control of food intake in the rat. Proc Roy Soc B 140: 578-592 (1952).
-
(1952)
Proc Roy Soc B
, vol.140
, pp. 578-592
-
-
Kennedy, G.C.1
-
2
-
-
0014682035
-
Regulation of energy balance
-
Hervey GR: Regulation of energy balance. Nature (Lond) 222: 629-631 (1969).
-
(1969)
Nature (Lond)
, vol.222
, pp. 629-631
-
-
Hervey, G.R.1
-
4
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffel M, Barone M, Leopold L, Friedman JM: Positional cloning of the mouse obese gene and its human homologue. Nature 372: 425-432 (1994).
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffel, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
5
-
-
0029066265
-
Effects of the obese gene product on body weight regulation in ob/ob mice
-
Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T, Collins F: Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269: 540-543 (1995).
-
(1995)
Science
, vol.269
, pp. 540-543
-
-
Pelleymounter, M.A.1
Cullen, M.J.2
Baker, M.B.3
Hecht, R.4
Winters, D.5
Boone, T.6
Collins, F.7
-
6
-
-
0029048408
-
Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
-
Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P: Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks. Science 269: 546-549 (1995).
-
(1995)
Science
, vol.269
, pp. 546-549
-
-
Campfield, L.A.1
Smith, F.J.2
Guisez, Y.3
Devos, R.4
Burn, P.5
-
7
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese gene
-
Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM: Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269: 543-546 (1995).
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.L.1
Gajiwala, K.S.2
Maffei, M.3
Cohen, S.L.4
Chait, B.T.5
Rabinowitz, D.6
Lallone, R.L.7
Burley, S.K.8
Friedman, J.M.9
-
8
-
-
0029939065
-
Decreased food intake does not completely account for adiposity reduction after ob protein infusion
-
Levin N, Nelson C, Gurney A, Vandlen R, de Sauvage F: Decreased food intake does not completely account for adiposity reduction after ob protein infusion. Proc Nat Acad Sci USA 93: 1726-1730 (1996).
-
(1996)
Proc Nat Acad Sci USA
, vol.93
, pp. 1726-1730
-
-
Levin, N.1
Nelson, C.2
Gurney, A.3
Vandlen, R.4
De Sauvage, F.5
-
9
-
-
15844409555
-
Role of leptin in fat regulation
-
Collins S, Kuhn CM, Petro AE, Gwick AG, Chrunyk BA, Surwit RS: Role of leptin in fat regulation. Nature 380: 677 (1996).
-
(1996)
Nature
, vol.380
, pp. 677
-
-
Collins, S.1
Kuhn, C.M.2
Petro, A.E.3
Gwick, A.G.4
Chrunyk, B.A.5
Surwit, R.S.6
-
10
-
-
15844410399
-
Obese gene expression alters the ability of 30A5 preadipocytes to respond to lipogenic hormones
-
Bai Y, Zhang S, Kyung-Sup K, Lee J-K, Kim HK: Obese gene expression alters the ability of 30A5 preadipocytes to respond to lipogenic hormones. J Biol Chem 271: 13939-13942 (1996).
-
(1996)
J Biol Chem
, vol.271
, pp. 13939-13942
-
-
Bai, Y.1
Zhang, S.2
Kyung-Sup, K.3
Lee, J.-K.4
Kim, H.K.5
-
11
-
-
0029118124
-
Increased expression in adipocytes of ob RNA in mice lesions of the hypothalamus and with mutations at the db locus
-
Maffei M, Fei H, Lee G-H, Leroy C, Zhang Y, Proenca R, Negrel R, Ailhaus G, Friedman JM: Increased expression in adipocytes of ob RNA in mice lesions of the hypothalamus and with mutations at the db locus. Proc Natl Acad Sci USA 92: 6957-6960 (1995).
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 6957-6960
-
-
Maffei, M.1
Fei, H.2
Lee, G.-H.3
Leroy, C.4
Zhang, Y.5
Proenca, R.6
Negrel, R.7
Ailhaus, G.8
Friedman, J.M.9
-
12
-
-
0029086176
-
Molecular cloning of rat obese cDNA and augmented gene expression in genetically obese Zucker fatty (fa/fa) rats
-
Ogawa Y, Masuzaki N, Isse N, Okazaki T, Mori K, Shigemoto M, Satoh N, Tamura N, Hosoda K, Yoshimasa Y, Jingami H, Kawada T, Nakao K: Molecular cloning of rat obese cDNA and augmented gene expression in genetically obese Zucker fatty (fa/fa) rats. J Clin Invest 96: 1647-1652 (1995).
-
(1995)
J Clin Invest
, vol.96
, pp. 1647-1652
-
-
Ogawa, Y.1
Masuzaki, N.2
Isse, N.3
Okazaki, T.4
Mori, K.5
Shigemoto, M.6
Satoh, N.7
Tamura, N.8
Hosoda, K.9
Yoshimasa, Y.10
Jingami, H.11
Kawada, T.12
Nakao, K.13
-
13
-
-
17444442925
-
Augmented expression of obese (ob) gene during the process of obesity in genetically obese-hyperglycemic Wistar fatty (fa/fa) rats
-
Masuzaki H, Hosoda K, Ogawa Y, Shigemoto M, Satoh N, Mori K, Tamura N, Nishi S, Yoshimasa Y, Yamori Y, Nakao K: Augmented expression of obese (ob) gene during the process of obesity in genetically obese-hyperglycemic Wistar fatty (fa/fa) rats. FEBS Lett 378: 267-271 (1996).
-
(1996)
FEBS Lett
, vol.378
, pp. 267-271
-
-
Masuzaki, H.1
Hosoda, K.2
Ogawa, Y.3
Shigemoto, M.4
Satoh, N.5
Mori, K.6
Tamura, N.7
Nishi, S.8
Yoshimasa, Y.9
Yamori, Y.10
Nakao, K.11
-
14
-
-
0028841201
-
Augmented expression of the obese gene in the adipose tissue from rats fed high-fat diet
-
Masuzaki H, Ogawa Y, Hosoda K, Kawada T, Fushiki T, Nakao K: Augmented expression of the obese gene in the adipose tissue from rats fed high-fat diet. Biochem Biophys Res Commun 216: 355-358 (1995).
-
(1995)
Biochem Biophys Res Commun
, vol.216
, pp. 355-358
-
-
Masuzaki, H.1
Ogawa, Y.2
Hosoda, K.3
Kawada, T.4
Fushiki, T.5
Nakao, K.6
-
15
-
-
0029021599
-
Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake
-
De Vos P, Saladin R, Auwerx J, Staels BJ: Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake. J Biol Chem 270: 15958-15961 (1995)
-
(1995)
J Biol Chem
, vol.270
, pp. 15958-15961
-
-
De Vos, P.1
Saladin, R.2
Auwerx, J.3
Staels, B.J.4
-
16
-
-
0029157428
-
Transient increase in obese gene expression after food intake or insulin administration
-
Saladin R, De Vos P, Guerre-Millo M, Leturque A, Girard J, Staels B, Auwerx J: Transient increase in obese gene expression after food intake or insulin administration. Nature 377: 527-529 (1995).
-
(1995)
Nature
, vol.377
, pp. 527-529
-
-
Saladin, R.1
De Vos, P.2
Guerre-Millo, M.3
Leturque, A.4
Girard, J.5
Staels, B.6
Auwerx, J.7
-
17
-
-
0029092010
-
Diet- and diabetes-induced changes of ob gene exxpression in rat adipose tissue
-
Becker DJ, Ongemba LN, Brichard V, Henquin JC, Brichard SM: Diet- and diabetes-induced changes of ob gene exxpression in rat adipose tissue. FEBS Lett 371: 324-328 (1995).
-
(1995)
FEBS Lett
, vol.371
, pp. 324-328
-
-
Becker, D.J.1
Ongemba, L.N.2
Brichard, V.3
Henquin, J.C.4
Brichard, S.M.5
-
18
-
-
0028821861
-
The ob gene and insulin
-
Cusin I, Sainsbury A, Doyle P, Rohner-Jeanrenaud F, Jeanrenaud B: The ob gene and insulin. Diabetes 44: 1467-1470 (1995).
-
(1995)
Diabetes
, vol.44
, pp. 1467-1470
-
-
Cusin, I.1
Sainsbury, A.2
Doyle, P.3
Rohner-Jeanrenaud, F.4
Jeanrenaud, B.5
-
19
-
-
0029665017
-
Acute and chronic effect of insulin on leptin production in humans: Studies in vivo and in vitro
-
Kolaczynski JW, Nyce MR, Considine RV, Boden G, Nolan JJ, Henry R, Mudaliar SR, Olefsky J, Caro JF: Acute and chronic effect of insulin on leptin production in humans: studies in vivo and in vitro. Diabetes 45: 699-701 (1996).
-
(1996)
Diabetes
, vol.45
, pp. 699-701
-
-
Kolaczynski, J.W.1
Nyce, M.R.2
Considine, R.V.3
Boden, G.4
Nolan, J.J.5
Henry, R.6
Mudaliar, S.R.7
Olefsky, J.8
Caro, J.F.9
-
20
-
-
0028826355
-
Acute cold-induced suppression of ob (obese) gene expression in white adipose tissue of mice: Mediation by the sympathetic system
-
Trayhurn P, Duncan S, Rayner DV: Acute cold-induced suppression of ob (obese) gene expression in white adipose tissue of mice: mediation by the sympathetic system. Biochem J 311: 729-733 (1995).
-
(1995)
Biochem J
, vol.311
, pp. 729-733
-
-
Trayhurn, P.1
Duncan, S.2
Rayner, D.V.3
-
21
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng X, Ellis SJ, Lakey ND, Culpepper J, Moore KJ, Breitbrt RE, Duyk GM, Tepper RI, Morgenstern JP: Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice. Cell 84: 491-495 (1996).
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
Ellis, S.J.6
Lakey, N.D.7
Culpepper, J.8
Moore, K.J.9
Breitbrt, R.E.10
Duyk, G.M.11
Tepper, R.I.12
Morgenstern, J.P.13
-
22
-
-
0030028959
-
Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (Leptin) receptor
-
Chua SC, Chung WK, Wu-Peng SX, Zhang Y, Liu SM, Tartaglia L, Leibel RL: Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (Leptin) receptor. Science 271: 994-996 (1996).
-
(1996)
Science
, vol.271
, pp. 994-996
-
-
Chua, S.C.1
Chung, W.K.2
Wu-Peng, S.X.3
Zhang, Y.4
Liu, S.M.5
Tartaglia, L.6
Leibel, R.L.7
-
23
-
-
0023184946
-
Adipocyte insulin resistance: Effects of aging, obesity, exercise, and food restriction
-
Craig BW, Garthwaite SM, Holloszy JO: Adipocyte insulin resistance: effects of aging, obesity, exercise, and food restriction. J Appl Physiol 62: 95-100 (1987).
-
(1987)
J Appl Physiol
, vol.62
, pp. 95-100
-
-
Craig, B.W.1
Garthwaite, S.M.2
Holloszy, J.O.3
-
24
-
-
0025804528
-
Interaction between exercise and food restriction: Effects on longevity of male rats
-
Holloszy JO, Schechtman KB: Interaction between exercise and food restriction: effects on longevity of male rats. J Appl Physiol 70: 1529-1535 (1991).
-
(1991)
J Appl Physiol
, vol.70
, pp. 1529-1535
-
-
Holloszy, J.O.1
Schechtman, K.B.2
-
25
-
-
0001717747
-
Model of obesity, non-insulin dependent diabetes, and congestive heart failure
-
McCune SA, Baker PB, Stills HF: Model of obesity, non-insulin dependent diabetes, and congestive heart failure. Laboratory Animal Research News 32: 23-27 (1990).
-
(1990)
Laboratory Animal Research News
, vol.32
, pp. 23-27
-
-
McCune, S.A.1
Baker, P.B.2
Stills, H.F.3
-
26
-
-
0002682415
-
-
E. Shafrir, Ed. Smith-Gordenn, London
-
McCune SA, Radin MJ, Jenkins JE, Chu YY, Park S, Peterson RG: In: Lessons from animal diabetes-V (E. Shafrir, Ed.) Smith-Gordenn, London (1995), 255-270.
-
(1995)
Lessons from Animal Diabetes-V
, pp. 255-270
-
-
McCune, S.A.1
Radin, M.J.2
Jenkins, J.E.3
Chu, Y.Y.4
Park, S.5
Peterson, R.G.6
-
27
-
-
0000426949
-
cp rats with antihypertensive drugs, nifedipine and enalapril: Effects on body weight, fat distribution, insulin resistance and systolic pressure
-
cp rats with antihypertensive drugs, nifedipine and enalapril: Effects on body weight, fat distribution, insulin resistance and systolic pressure. Obesity Research 1: 433-442 (1993).
-
(1993)
Obesity Research
, vol.1
, pp. 433-442
-
-
Radin, M.J.1
Chu, Y.Y.2
Hoepf, T.M.3
McCune, S.F.4
-
28
-
-
0029887358
-
Involvement of transcription factor C/EBP-β in stimulation of PEPCK gene expression during exercise
-
Nizielski SE, Arizmendi C, Shteyngarts AR, Farrell CJ, Friedman JE: Involvement of transcription factor C/EBP-β in stimulation of PEPCK gene expression during exercise. Am J Physiol 39: R1005-R1012 (1996).
-
(1996)
Am J Physiol
, vol.39
-
-
Nizielski, S.E.1
Arizmendi, C.2
Shteyngarts, A.R.3
Farrell, C.J.4
Friedman, J.E.5
-
29
-
-
0028784214
-
Over-expression of the obese gene in the genetically obese JCR: LA-corpulent rat
-
Vydelingum S, Shillabeer G, Hatch G, Russell JC, Lau DCW: Over-expression of the obese gene in the genetically obese JCR: LA-corpulent rat. Biochem Biophys Res Comm 216: 148-153 (1996).
-
(1996)
Biochem Biophys Res Comm
, vol.216
, pp. 148-153
-
-
Vydelingum, S.1
Shillabeer, G.2
Hatch, G.3
Russell, J.C.4
Lau, D.C.W.5
-
30
-
-
0017371691
-
Genetics of obesity of Zucker rat and Koletsky rats
-
Yen T, Shaw WN, Yu P: Genetics of obesity of Zucker rat and Koletsky rats. Heredity 38: 373-377 (1977).
-
(1977)
Heredity
, vol.38
, pp. 373-377
-
-
Yen, T.1
Shaw, W.N.2
Yu, P.3
-
31
-
-
0030267744
-
Nonsense mutation of leptin receptor in the obese spontaneously hypertensive Koletsky rat
-
Takaya K, Ogawa Y, Hiaoka J, Hosoda K, Yamori Y, Nakao K, Koletsky RJ: Nonsense mutation of leptin receptor in the obese spontaneously hypertensive Koletsky rat. Nature Genetics 14: 203-205 (1996).
-
(1996)
Nature Genetics
, vol.14
, pp. 203-205
-
-
Takaya, K.1
Ogawa, Y.2
Hiaoka, J.3
Hosoda, K.4
Yamori, Y.5
Nakao, K.6
Koletsky, R.J.7
-
32
-
-
0029763177
-
The weight reducing effect of an intracerebroventricular bolus injection of leptin in genetically obese fa/fa rats
-
Cusin I, Rohner-Jeanrenaud R, Stricker-Krongrad A, Jeanrenaud B: The weight reducing effect of an intracerebroventricular bolus injection of leptin in genetically obese fa/fa rats. Diabetes 45: 1446-1450 (1996).
-
(1996)
Diabetes
, vol.45
, pp. 1446-1450
-
-
Cusin, I.1
Rohner-Jeanrenaud, R.2
Stricker-Krongrad, A.3
Jeanrenaud, B.4
-
33
-
-
0028793697
-
Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action
-
Frederich A, Hamann S, Anderson B, Lollmann B, Lowell BB, Flier JS: Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nature Med 1: 1311-1314 (1995).
-
(1995)
Nature Med
, vol.1
, pp. 1311-1314
-
-
Frederich, A.1
Hamann, S.2
Anderson, B.3
Lollmann, B.4
Lowell, B.B.5
Flier, J.S.6
|