In vitro effects of nitric oxide synthase inhibitor L-NAME on oral squamous cell carcinoma: a preliminary study

International Journal of Oral and Maxillofacial Surgery

Volumn 35, Issue 6, 2006, Pages 539-543

  Shang, Z J ^a,b   Li, Z B ^b   Li, J R ^b  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b WUHAN UNIVERSITY   (China)

Author keywords

cellular proliferation; DNA RNA synthesis; nitric oxide; nitric oxide synthase; oral squamous cell carcinoma

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ACRIDINE ORANGE; CRYSTAL VIOLET; DNA; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; RNA;

ARTICLE; BIOSYNTHESIS; CANCER CONTROL; CARCINOGENESIS; CARCINOMA CELL; CASE REPORT; CELL ASSAY; CELL GROWTH; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SYNTHESIS; DOWN REGULATION; DRUG EFFECT; DRUG EXPOSURE; DRUG MECHANISM; GENE EXPRESSION; GENE EXPRESSION REGULATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; IN VITRO STUDY; MOUTH CARCINOMA; PROTEIN FUNCTION; RNA SYNTHESIS; SQUAMOUS CELL CARCINOMA; TIME; TONGUE CARCINOMA; TUMOR VASCULARIZATION;

ACRIDINE ORANGE; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; COLORING AGENTS; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; FLUORESCENT DYES; GENTIAN VIOLET; HUMANS; IN SITU HYBRIDIZATION; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; NITROUS OXIDE; RNA; TETRAZOLIUM SALTS; THIAZOLES; TONGUE NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 33646527580     PISSN: 09015027     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijom.2006.01.004     Document Type: Article

References (25)

1. Albina J.E., and Reichmer J.S. Role of nitric oxide in mediation macrophage cytotoxicity and apoptosis. Cancer Metastasis Rev 17 (1998) 39-53
2. Ambs S., Hussain S.P., and Harris C.C. Interactive effects of nitric oxide and the p53 tumor suppressor gene in carcinogenesis and tumor progression. FASEB J 11 (1997) 443-448
3. Arnal J.F., Yamin J., Dockery S., and Harrison D.G. Regulation of endothelial nitric oxide synthase mRNA, protein, and activity during cell growth. Am J Physiol 267 (1994) C1381-C1388
4. Bauer K.S., Cude K.J., Dixon S.C., Kruger E.A., and Figg W.D. Carboxyamido-triazole inhibits angiogenesis by blocking the calcium-mediated nitric-oxide synthase-vascular endothelial growth factor pathway. J Pharmacol Exp Ther 292 (2000) 31-37
5. Bentz B.G., Haines III G.K., Lingen M.W., Pelzer H.J., Hanson D.G., and Radosevich J.A. Nitric oxide synthase type 3 is increased in squamous hyperplasia, dysplasia, and squamous cell carcinoma of the head and neck. Ann Otol Rhinol Laryngol 108 (1999) 781-787
6. Brennan P.A., Downie I.P., Langdon J.D., and Zaki G.A. Emerging role of nitric oxide in cancer. Br J Oral Maxillofac Surg 37 (1999) 370-373
7. Brennan P.A., Palacios-Callender M., Umar T., Hughes D., Spedding A.V., Zaki G.A., and Langdon J.D. Correlation between Type II nitric oxide synthase and p53 expression in oral squamous cell carcinoma. Br J Oral Maxillofac Surg 38 (2000) 627-632
8. Brennan P.A., Palacios-Callender M., Zaki G.A., Spedding A.V., and Langdon J.D. Type II nitric oxide synthase (NOS2) expression correlates with lymph node status in oral squamous cell carcinoma. J Oral Pathol Med 30 (2001) 129-134
9. Brennan P.A., Thomas G.J., and Langdon J.D. The role of nitric oxide in oral diseases. Arch Oral Biol 1274 (2002) 1-8
10. Forstermann U., and Kleinert H. Nitric oxide synthase: expression and expressional control of the three isoforms. Naunyn-Schmiedebergs Arch Pharmacol 352 (1995) 351-364
11. Gallo O., Masini E., Morbidelli L., Franchi A., Fini-Storchi I., Vergari W.A., and Ziche M. Role of nitric oxide in angiogenesis and tumor progression in head and neck cancer. J Natl Cancer Inst 90 (1998) 587-596
12. Hajri A., Metzger E., Vallat F., Coffy S., Flatter E., Evrard S., Marescaux J., and Aprahamian M. Role of nitric oxide in pancreatic tumour growth: in vivo and in vitro studies. Br J Cancer 78 (1998) 841-849
13. Hood J.D., Meininger C.J., Ziche M., and Granger H.J. VEGF upregulates ecNOS message, protein, and NO production in human endothelial cells. Am J Physiol 274 (1998) H1054-H1058
14. Igarashi J., and Michel T. Sphingosine 1-phosphate and isoform-specific activation of phosphoinositide 3-kinase beta. Evidence for divergence and convergence of receptor-regulated endothelial nitric-oxide synthase signaling pathways. J Biol Chem 276 (2001) 36281-36288
15. Klotz T., Bloch W., Volberg C., Engelmann U., and Addicks K. Selective expression of inducible nitric oxide synthase in human prostate carcinoma. Cancer 82 (1998) 1897-1903
16. Kröncke K.D., Fehsel K., and Kolb-Bachofen V. Inducible nitric oxide synthase and its product nitric oxide, a small molecule with complex biological activities. Biol Chem Hoppe Seyler 376 (1995) 327-343
17. Liu R., Oberley T.D., and Oberley L.W. Effects of endothelial nitric oxide synthase gene expression on the tumor biology of human oral carcinoma SCC-25 cells. Cell Growth Differ 9 (1998) 239-246
18. Nathan C., and Xie Q.W. Nitric oxide synthase: roles, tools and controls. Cell 78 (1994) 915-918
19. G-Nitro-l-arginine methyl ester, an inhibitor of nitric oxide synthesis, ameliorates interleukin 2-induced capillary leakage and reduces tumour growth in adenocarcinoma-bearing mice. Br J Cancer 73 (1996) 189-196
20. Rosbe K.W., Prazma J., Petrusz P., Mims W., Ball S.S., and Weissler M.C. Immunohistochemical characterization of nitric oxide synthase activity in squamous cell carcinoma of the head and neck. Otolaryngol Head Neck Surg 113 (1995) 541-549
21. Sagar S.M., Singh G., Hodson I., and Whitton A.C. Nitric oxide and anti-cancer therapy. Cancer Treat Rev 21 (1995) 159-181
22. Shang Z.J., and Li J.R. Expression of endothelial nitric oxide synthase and vascular endothelial growth factor in oral squamous cell carcinoma: its correlation with angiogenesis and disease progression. J Oral Pathol Med 34 (2005) 134-139
23. Shang Z.J., Li J.R., and Li Z.B. Effects of exogenous nitric oxide on oral squamous cell carcinoma: an in vitro study. J Oral Maxillofac Surg 60 (2002) 905-910
24. Vogelstein B. Cancer: a deadly inheritance. Nature 348 (1990) 681-682
25. Wink D.A., Vodovotz Y., Laval D., Laval F., Dewhirst D.W., and Mitchell J.B. The multifaceted roles of nitric oxide in cancer. Carcinogenesis 19 (1998) 711-721