Protective effect of bombesin receptor subtype-3 on human brochial epithelial cells against injury

Journal of Central South University (Medical Sciences)

Volumn 31, Issue 2, 2006, Pages 178-183

  Liu, Hui Jun ^a   Wang, Yue ^a   Qi, Ming Ming ^a   Qu, Fei ^a   Xiang, Yang ^a   Tan, Yu Rong ^a   Zhang, Chang Qing ^a   Qin, Xiao Qun ^a  

^a Central South University   (China)

Author keywords

Bombesin receptor subtype 3 (BRS 3); Human brachial epithelial cells; p3513

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BETA1 INTEGRIN; BOMBESIN ANTAGONIST; BOMBESIN RECEPTOR; CADHERIN; CALMODULIN INHIBITOR; CATALASE; L 3513; LACTATE DEHYDROGENASE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; OZONE; P 3513; PROTEIN TYROSINE KINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BRONCHUS INJURY; BRONCHUS MUCOSA; CELL PROLIFERATION; CELL PROTECTION; DRUG EFFECT; HUMAN; HUMAN CELL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; STRESS;

ANTIGENS, CD29; BRONCHI; CADHERINS; CATALASE; CELL LINE; CELL PROLIFERATION; EPITHELIAL CELLS; HUMANS; L-LACTATE DEHYDROGENASE; PROTECTIVE AGENTS; REACTIVE OXYGEN SPECIES; RECEPTORS, BOMBESIN;

EID: 33646513960     PISSN: 16727347     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Spindel ER, Giladi E, Segerson TP, et al. Bombesin-like peptides: ligands and receptors [J]. Recent Prog Horm Res, 1993, 48:365-391.
2. Kroog GS, Jensen RT, Battey JF, et al. Mammalian bombesin receptor [J]. Med Res Rev, 1995, 15(5):389-417.
3. Wu ZY, Zhan WH, Li JH, et al. Expression of E-cadherin in gastric carcinoma and its correlation with lymph node micrometastasis [J]. World J Gastroenterol, 2005, 11(20): 3139-3143.
4. White SR, Dorscheid DR, Rabe KF, et al. Role of very late adhesion integrins in mediating repair of human airway epithelial cell monolayers after mechanical injury [J]. Am J Respir Cell Mol Biol, 1999, 20(4):787-796.
5. Ryan RR. Ability of various bombesin receptor agonists and antagonists to alter intracellular signaling of the human orphan receptor BRS-3 [J]. J Biol Chem, 273(22):13613-13624.
6. Comhair SA, Superoxide dismutase inactivation in pathophysiology of asthmatic airway remodeling and reactivity [J]. Am J Pathol, 2005, 166(3):663-674.
7. Lammerich HP, Lammerich HP, Busmann A, et al. Identification and functional characterization of hemorphins VV-H-7 and LVV-H-7 as low-affinity agonists for the orphan bombesin receptor subtype 3 [J]. Br J Pharmacol, 2003, 138(8):1431-1440.
8. Weber HC, Walters J, Leyton J, et al. A bombesin receptor subtype-3 peptide increases nuclear oncogene expression in a MEK-1 dependent manner in human lung cancer cells [J]. Eur J Pharmacol, 2001, 412(1):13-20.