Analgesic and anticonvulsant effects of extracts from the leaves of Kalanchoe crenata (Andrews) Haworth (Crassulaceae)

Journal of Ethnopharmacology

Volumn 106, Issue 1, 2006, Pages 70-75

  Nguelefack, T B ^a   Nana, P ^b   Atsamo, A D ^a   Dimo, T ^b   Watcho, P ^a   Dongmo, A B ^c   Tapondjou, L A ^a   Njamen, D ^b   Wansi, S L ^a   Kamanyi, A ^a  

^a UNIVERSITY OF DSCHANG   (Cameroon)

^b UNIVERSITY OF YAOUNDÉ I   (Cameroon)

^c UNIVERSITY OF DOUALA   (Cameroon)

Author keywords

Analgesia; Anticonvulsant; Kalanchoe crenata; Leaves

Indexed keywords

ACETIC ACID; ACETIC ACID ETHYL ESTER; BUTANOL; CARBAMAZEPINE; COCODAMOL; DICHLOROMETHANE; FORMALDEHYDE; HEXANE; INDOMETACIN; KALANCHOE CRENATA EXTRACT; METHANOL; PENTETRAZOLE; PLANT EXTRACT; STRYCHNINE; STRYCHNINE SULFATE; THIOSEMICARBAZIDE; UNCLASSIFIED DRUG; VALPROIC ACID;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CAUSE OF DEATH; CONTROLLED STUDY; CRASSULACEAE; DISEASE DURATION; DRUG DETERMINATION; DRUG SCREENING; DRUG SYNTHESIS; FEMALE; GRAND MAL SEIZURE; KALANCHOE; LATENT PERIOD; MALE; MOUSE; NOCICEPTION; NONHUMAN; PAIN; PLANT LEAF; PRESSURE; RAT; SEIZURE; TONIC CLONIC SEIZURE;

ANALGESICS; ANIMALS; ANTICONVULSANTS; CONVULSANTS; FEMALE; KALANCHOE; MALE; MICE; PENTYLENETETRAZOLE; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; RATS; RATS, WISTAR; SEIZURES; SEMICARBAZIDES;

ANIMALIA; CRASSULACEAE; KALANCHOE; KALANCHOE INTEGRA CRENATA; STRYCHNOS TOXIFERA;

EID: 33646512822     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2005.12.003     Document Type: Article

References (29)

1. Adinike K., and Eretan O.B. Purification and partial characterization of lectin from the fresh leaves of Kalanchoe crenata (And.) Haw. Journal of Biochemistry and Molecular Biology 37 (2004) 229-233
2. Adjanohoun J.C., Aboubakar N., Dramasse K., Ebot M.E., Ekpere J.A., Enow-Orock E.G., Focho D., Gbile Z.O., Kamanyi A., Kamsu Kom Jr. P., Keeta A., Mbenkum T., Mbi C.M., Mbielle A.L., Mbome I.L., Mubiru N.K., Namey W.L., Nkongmeneck B., Stabie B., Sofowa A., Tanze V., and Wirmum C.K. Traditional Medicine and Pharmacopeia-Contribution to Ethnobotanical and Floristic studies in Cameroon (1996), CNPMS, Porto-novo, Benin p. 505
3. Cechinel Filho V., Santos A.R.S., De Campos R.O.P., Miguel O.G., Yunes R.A., Ferrari F., Messana I., and Calixto J.B. Chemical and pharmacological studies of Phyllanthus carolinienses in mice. Journal of Pharmacy and Pharmacology 48 (1996) 1231-1236
4. Contreras C.M., Chacon L., and Enriquez R.G. Anticonvulsant properties of Ipomoea stans. Phytomedicine 3 (1996) 41-44
5. Corda M.G., Giorgi O., Longoni B., Orlandi M., and Biggio G. Decrease in the function of the g-aminobutyric acid-coupled chloride channel produced by the repeated administration of pentylenetetrazol to rats. Journal of Neurochemistry 55 (1990) 1221-1261
6. De Potter W.P., De Potter R.W., De Smett F.H., and De Schaepdryver A.F. The effects of drugs on the concentration of DbH in the CSF of rabbits. Neuroscience 5 (1980) 1969-1977
7. Gaertner M., Müller L., Roos J.F., Cani G., Santos A.R.S., Niero R., Calixto J.B., Yunes R.A., Delle Manache F., and Cechinel-Filho V. Analgesic triterpenes from Sebastiania Schottiana roots. Phytomedicine 6 (1999) 41-44
8. Garcia M.D., Fernandez M.A., Alvarez A., and Saenz M.T. Antinociceptive and anti-inflammatory effect of the aqueous extract from leaves of Pimenta racemosa var. ozua (Mirtaceae). Journal of Ethnopharmacology 91 (2004) 29-73
9. Letouzey, R., 1982. Manuel de botanique forestière. Afrique tropicale, tome 2A, centre technique forestière tropicale. pp. 45-47.
10. Löscher W., and Schmidt D. Which animal model should be used in the search for new anti-epileptic drugs? A proposal based on experimental and clinical considerations. Epilepsy Research 2 (1988) 145-181
11. McCleane G.J. Lamotrigine in the management of neuropathic pain: a review of the literature. The Clinical Journal of Pain 16 (2000) 321-326
12. McCleane G., Koch B., and Rauschkolb C. Does SPM 927 have an analgesic effect in human neuropathic pain? An open label study. Neuroscience Letters 352 (2003) 117-120
13. McQuay G.J., Carroll D., Jadad A.R., Wiffen P., and Moore A. Anticonvulsant drugs for management of pain: a systematic review. British Medical Journal 311 (1995) 1047-1052
14. Murray C.W., Porreca F., and Cowan A. Methodological refinement in the mouse paw formalin test: an animal model of tonic pain. Journal of Pharmacological Methods 20 (1988) 175-186
15. Nassis C.Z., Haebisch E.M., and Giesbrecht A.M. Antihistamine activity of Bryophyllum calycinum. Brazilian Journal of Medicine and Biological Research 25 (1992) 929-936
16. Ngo Bum E.N., Schmutz M., Meyer C., Rakotonirina A., Rakotonirina S.V., Olpe H.R., and Herrling P. Anticonvulsant properties of the methanolic extract of Cyprus articulatus (Cyperaceae). Journal of Ethnopharmacology 76 (2001) 145-150
17. Nguelefack T.B., Fotio L.A., Watcho P., Wansi S., Dimo T., and Kamanyi A. Analgesic activities of aqueous and ethanolic extracts of the leaves of Kalanchoe crenata (Crassulaceae). Phytotherapy Research 18 (2004) 385-388
18. Nogueira R.M.D., Costa D.C., Patrocínio M.C.A., Camarão G.C., Uchoa D.E.A., Silveira E.R., Scorza F.A., Santos N.F., Cavalheiro E.A., and Carvalho K.M. Status epilepticus induced by marinobufagin, a bufadienolide isolated from Bufo paracnemis lutz (1925) parotid glands secretions. Journal of Venomous Animals and Toxins including Tropical Diseases 9 (2003) 95-96
19. Pal S., Sen T., and Nag Chaudhuri A.K. Neuropsychopharmacological profile of the methanolic fraction of Bryophyllum pinnatum leaf extract. Journal of Pharmacy and Pharmacology 51 (1999) 313-318
20. Rowbotham M., Harden N., Stacey B., Bernstein P., and Magnusmiller L. Gabapentin for the treatment of post-herpetic neuralgia. A randomised controlled trial. The Journal of the American Medical Association 280 (1998) 1837-1842
21. Santos A.R.S., Neiro R., Cechinel Filho V., Yunes R.A., Pizzolatti M.G., Delle Monache F., and Calixto J.B. Antinoceptive properties of steroids isolated from Phyllanthus corcovadensis. Planta Medica 61 (1995) 329-331
22. Schowb M., and Dubost M.C. Entendre la douleur (1984), Pharmapost, RC Montargis, France p. 99
23. Sofowora A. Medicinal Plants and Traditional Medicine in Africa. 2nd ed. (1993), Polygraphie ventures Ltd., Ibadan, Nigeria pp. 207-209
24. Stai H.Y., Chen Y.F., and Wu T.S. Anti-inflammatory and analgesic activities of extract from roots of Angelica pubescens. Planta Medica 61 (1995) 1-8
25. Supratman U., Tomoyuki F., Akiyama K., Hayashi H., Murakami A., Sahai H., Koshimizu K., and Ohigashi H. Anti-tumor promoting activity of bufadienolides from Kalanchoe pinnata and K. daigremontiana × tubiflora. Bioscience Biotechnology Biochemistry 65 (2001) 947-949
26. Taylor L. The Healing Power of Rainforest Herbs (2005), Raintree Nutrition Inc., Carson City, NV 89701
27. Tjosen A., Berge D.G., Hunskaar S., Rosland J.H., and Hole K. The formalin test: an evaluation of the method. Pain 51 (1992) 5-17
28. Wagner H., and Bladt S. Plant Drug Analysis: A Thin Layer Chromatography Atlas. 2nd ed. (1996), Springer, Berlin p. 384
29. Wagner H., Fischer M., and Lotter H. Isolation and structure determination of daigremontianin, a novel bufadienolide from Kalanchoe daigermontiana. Planta Medica (1985) 169-170