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Volumn 168, Issue 5, 2006, Pages 1631-1641

Expression and oncogenic role of Brk (PTK6/Sik) protein tyrosine kinase in lymphocytes

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; PROTEIN TYROSINE KINASE; SMALL INTERFERING RNA;

EID: 33646506878     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2006.050521     Document Type: Article
Times cited : (34)

References (29)
  • 3
    • 0038499519 scopus 로고    scopus 로고
    • Brk, Srm, Frk, and Src42A form a distinct family of intracellular Src-like tyrosine kinases
    • Serfas MS, Tyner AL: Brk, Srm, Frk, and Src42A form a distinct family of intracellular Src-like tyrosine kinases. Oncol Res 2003, 13:409-419
    • (2003) Oncol Res , vol.13 , pp. 409-419
    • Serfas, M.S.1    Tyner, A.L.2
  • 4
    • 0030827253 scopus 로고    scopus 로고
    • BRK tyrosine kinase expression in a high proportion of human breast carcinomas
    • Barker KT, Jackson LE, Crompton MR: BRK tyrosine kinase expression in a high proportion of human breast carcinomas. Oncogene 1997, 15:799-805
    • (1997) Oncogene , vol.15 , pp. 799-805
    • Barker, K.T.1    Jackson, L.E.2    Crompton, M.R.3
  • 5
    • 0038679380 scopus 로고    scopus 로고
    • Elevated expression levels of NCOA3, TOP1, and TFAP2C in breast tumors as predictors of poor prognosis
    • Zhao C, Yasui K, Lee CJ, Kurioka H, Hosokawa Y, Oka T, Inazawa J: Elevated expression levels of NCOA3, TOP1, and TFAP2C in breast tumors as predictors of poor prognosis. Cancer 2003, 98:18-23
    • (2003) Cancer , vol.98 , pp. 18-23
    • Zhao, C.1    Yasui, K.2    Lee, C.J.3    Kurioka, H.4    Hosokawa, Y.5    Oka, T.6    Inazawa, J.7
  • 6
    • 17144412880 scopus 로고    scopus 로고
    • Simultaneous over-expression of the Her2/neu and PTK6 tyrosine kinases in archival invasive ductal breast carcinomas
    • Born M, Quintanilia-Fend L, Braselmann H, Reich U, Richter M, Hutzler P, Aubele M: Simultaneous over-expression of the Her2/neu and PTK6 tyrosine kinases in archival invasive ductal breast carcinomas. J Pathol 2005, 205:592-596
    • (2005) J Pathol , vol.205 , pp. 592-596
    • Born, M.1    Quintanilia-Fend, L.2    Braselmann, H.3    Reich, U.4    Richter, M.5    Hutzler, P.6    Aubele, M.7
  • 7
    • 0030970669 scopus 로고    scopus 로고
    • Loss of expression of receptor tyrosine kinase famiiy genes PTK7 and SEK in metastatic meianoma
    • Easty DJ, Mitchell PJ, Patel K, Florenes VA, Spritz RA, Bennett DC: Loss of expression of receptor tyrosine kinase famiiy genes PTK7 and SEK in metastatic meianoma. Int J Cancer 1997, 71:1061-1065
    • (1997) Int J Cancer , vol.71 , pp. 1061-1065
    • Easty, D.J.1    Mitchell, P.J.2    Patel, K.3    Florenes, V.A.4    Spritz, R.A.5    Bennett, D.C.6
  • 10
    • 7044230899 scopus 로고    scopus 로고
    • Differential expression of the non-receptor tyrosine kinase BRK in oral squamous cell carcinoma and normal oral epithelium
    • Petro BJ, Tan RC, Tyner AL, Lingen MW, Watanabe K: Differential expression of the non-receptor tyrosine kinase BRK in oral squamous cell carcinoma and normal oral epithelium. Oral Oncol 2004, 40:1040-1047
    • (2004) Oral Oncol , vol.40 , pp. 1040-1047
    • Petro, B.J.1    Tan, R.C.2    Tyner, A.L.3    Lingen, M.W.4    Watanabe, K.5
  • 12
    • 0031461714 scopus 로고    scopus 로고
    • A role for the epithelial-cell-specific tyrosine kinase Sik during keratinocyte differentiation
    • Vasioukhin V, Tyner AL: A role for the epithelial-cell-specific tyrosine kinase Sik during keratinocyte differentiation. Proc Natl Acad Sci USA 1997, 94:14477-14482
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 14477-14482
    • Vasioukhin, V.1    Tyner, A.L.2
  • 13
    • 0038713797 scopus 로고    scopus 로고
    • Altered localization and activity of the intracellular tyrosine kinase BRK/Sik in prostate tumor cells
    • Derry JJ, Prins GS, Ray V, Tyner AL: Altered localization and activity of the intracellular tyrosine kinase BRK/Sik in prostate tumor cells. Oncogene 2003, 22:4212-4220
    • (2003) Oncogene , vol.22 , pp. 4212-4220
    • Derry, J.J.1    Prins, G.S.2    Ray, V.3    Tyner, A.L.4
  • 15
    • 23844532254 scopus 로고    scopus 로고
    • An intramolecular interaction between SH2-kinase linker and kinase domain is essential for the catalytic activity of protein-tyrosine kinase-6
    • Kim HI, Lee ST: An intramolecular interaction between SH2-kinase linker and kinase domain is essential for the catalytic activity of protein-tyrosine kinase-6. J Biol Chem 2005, 280:28973-28980
    • (2005) J Biol Chem , vol.280 , pp. 28973-28980
    • Kim, H.I.1    Lee, S.T.2
  • 16
    • 0042786007 scopus 로고    scopus 로고
    • Use of RNA interference to validate Brk as a novel therapeutic target in breast cancer: Brk promotes breast carcinoma cell proliferation
    • Harvey AJ, Crompton MR: Use of RNA interference to validate Brk as a novel therapeutic target in breast cancer: Brk promotes breast carcinoma cell proliferation. Oncogene 2003, 22:5006-5010
    • (2003) Oncogene , vol.22 , pp. 5006-5010
    • Harvey, A.J.1    Crompton, M.R.2
  • 17
    • 33644663231 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression
    • Lukong KE, Larocque D, Tyner AL, Richard S: Tyrosine phosphorylation of sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression. J Biol Chem 2005, 280:38639-38647
    • (2005) J Biol Chem , vol.280 , pp. 38639-38647
    • Lukong, K.E.1    Larocque, D.2    Tyner, A.L.3    Richard, S.4
  • 18
    • 10044284340 scopus 로고    scopus 로고
    • Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin
    • Chen HY, Shen CH, Tsai YT, Lin FC, Huang YP, Chen RH: Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin. Mol Cell Biol 2004, 24:10558-10572
    • (2004) Mol Cell Biol , vol.24 , pp. 10558-10572
    • Chen, H.Y.1    Ch, S.2    Tsai, Y.T.3    Lin, F.C.4    Huang, Y.P.5    Chen, R.H.6
  • 19
    • 25444439889 scopus 로고    scopus 로고
    • The intracellular tyrosine kinase Brk sensitizes non-transformed cells to inducers of apoptosis
    • Haegebarth A, Nunez R, Tyner AL: The intracellular tyrosine kinase Brk sensitizes non-transformed cells to inducers of apoptosis. Cell Cycle 2005, 4:1239-1246
    • (2005) Cell Cycle , vol.4 , pp. 1239-1246
    • Haegebarth, A.1    Nunez, R.2    Tyner, A.L.3
  • 20
    • 0038365301 scopus 로고    scopus 로고
    • Detection of protein tyrosine-kinase (PTK) gene expression pattern in normal and malignant T lymphocytes by combined PTK-specific PCR and parallel denaturing gradient gel electrophoresis (DGGE)
    • Wang ZY, Zhang Q, Wilson J, Ratajczak MZ, Wasik MA: Detection of protein tyrosine-kinase (PTK) gene expression pattern in normal and malignant T lymphocytes by combined PTK-specific PCR and parallel denaturing gradient gel electrophoresis (DGGE). J Mol Diagn 2003, 5:113-120
    • (2003) J Mol Diagn , vol.5 , pp. 113-120
    • Wang, Z.Y.1    Zhang, Q.2    Wilson, J.3    Ratajczak, M.Z.4    Wasik, M.A.5
  • 22
    • 24744435392 scopus 로고    scopus 로고
    • Activation of mTOR in transformed B lymphocytes is nutrient-dependent but independent of Akt MEK, IGF-I, and serum
    • Wlodarski P, Kasprzycka M, Liu X, Marzec M, Slupianek A, Wasik MA: Activation of mTOR in transformed B lymphocytes is nutrient-dependent but independent of Akt MEK, IGF-I, and serum. Cancer Res 2005, 65:7800-7808
    • (2005) Cancer Res , vol.65 , pp. 7800-7808
    • Wlodarski, P.1    Kasprzycka, M.2    Liu, X.3    Marzec, M.4    Slupianek, A.5    Wasik, M.A.6
  • 23
    • 9144223047 scopus 로고    scopus 로고
    • Short interfering RNA (SiRNA) targeting the Lyn kinase induces apoptosis in primary, and drug-resistant, BCR- ABL1(+) leukemia cells
    • Ptasznik A, Nakata Y, Kalota A, Emerson SG, Gewirtz AM: Short interfering RNA (SiRNA) targeting the Lyn kinase induces apoptosis in primary, and drug-resistant, BCR- ABL1(+) leukemia cells. Nat Med 2004, 10:1187-1189
    • (2004) Nat Med , vol.10 , pp. 1187-1189
    • Ptasznik, A.1    Nakata, Y.2    Kalota, A.3    Emerson, S.G.4    Gewirtz, A.M.5
  • 24
    • 0037072828 scopus 로고    scopus 로고
    • Regulation of the nonreceptortyrosine kinase Brk by autophosphorylation and by autoinhibition
    • Qiu H, Miller WT: Regulation of the nonreceptortyrosine kinase Brk by autophosphorylation and by autoinhibition. J Biol Chem 2002, 277:34634-34641
    • (2002) J Biol Chem , vol.277 , pp. 34634-34641
    • Qiu, H.1    Miller, W.T.2
  • 25
    • 0034636055 scopus 로고    scopus 로고
    • The immunosuppressive macrolide RAD inhibits growth of human Epstein-Barr virus-transformed B lymphocytes in vitro and in vivo: A potential approach to prevention and treatment of posttransplant lymphoproliferative disorders
    • Majewski M, Korecka M, Kossev P, Li S, Goldman J, Moore J, Silberstein L, Nowell PC, Schuler W, Shaw LM, Wasik MA: The immunosuppressive macrolide RAD inhibits growth of human Epstein-Barr virus-transformed B lymphocytes in vitro and in vivo: a potential approach to prevention and treatment of posttransplant lymphoproliferative disorders. Proc Natl Acad Sci USA 2000, 97:4285-4290
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 4285-4290
    • Majewski, M.1    Korecka, M.2    Kossev, P.3    Li, S.4    Goldman, J.5    Moore, J.6    Silberstein, L.7    Nowell, P.C.8    Schuler, W.9    Shaw, L.M.10    Wasik, M.A.11
  • 27
    • 0034676337 scopus 로고    scopus 로고
    • Expression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to Pl 3-kinase and Akt, via erbB3 phosphorylation
    • Kamalati T, Jolin HE, Fry MJ, Crompton MR: Expression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to Pl 3-kinase and Akt, via erbB3 phosphorylation. Oncogene 2000, 19:5471-5476
    • (2000) Oncogene , vol.19 , pp. 5471-5476
    • Kamalati, T.1    Jolin, H.E.2    Fry, M.J.3    Crompton, M.R.4
  • 29
    • 11144245896 scopus 로고    scopus 로고
    • The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2
    • Haegebarth A, Heap D, Bie W, Derry JJ, Richard S, Tyner AL: The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2. J Biol Chem 2004, 279:54398-54404
    • (2004) J Biol Chem , vol.279 , pp. 54398-54404
    • Haegebarth, A.1    Heap, D.2    Bie, W.3    Derry, J.J.4    Richard, S.5    Tyner, A.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.