Synthesis and in vitro evaluation of N-substituted aza-trozamicol analogs as vesicular acetylcholine transporter ligands

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 10, 2006, Pages 2654-2657

  Assaad, Thaer ^a,b   Mavel, Sylvie ^a,b   Parsons, Stanley M ^c   Kruse, Shane ^c   Galineau, Laurent ^a,b   Allouchi, Hassan ^a   Kassiou, Michael ^d,e   Chalon, Sylvie ^a,b   Guilloteau, Denis ^a,b   Emond, Patrick ^a,b  

^a UNIVERSITÉ DE TOURS   (France)

^b CHU BRETONNEAU   (France)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^e University of Sydney   (Australia)

Author keywords

VAChT; Vesamicol derivatives; Vesicular acetylcholine transporter

Indexed keywords

ALKYL GROUP; BENZYL DERIVATIVE; IODINE 125; LIGAND; NITROGEN; VESICULAR ACETYLCHOLINE TRANSPORTER; VINYL DERIVATIVE;

ALZHEIMER DISEASE; ARTICLE; BRAIN DYSFUNCTION; DRUG SYNTHESIS; HUMAN; IC 50; IN VITRO STUDY; IN VIVO STUDY; ISOMER; ISOTOPE LABELING; NEUROIMAGING; NEUROTRANSMISSION; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

ACETYLCHOLINE; CARRIER PROTEINS; LIGANDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33646483178     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.02.033     Document Type: Article

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