QSAR studies on benzopyran potassium channel activators

European Journal of Medicinal Chemistry

Volumn 41, Issue 3, 2006, Pages 360-366

  Agrawal, Vijay K ^a   Singh, Jyoti ^a   Gupta, Madhu ^b   Jaliwala, Yusuf Ali ^c   Khadikar, Padmakar V ^d   Supuran, Claudiu T ^e  

^a A P S UNIVERSITY   (India)

^b MMH College   (India)

^c Risiraj College of Pharmacy   (India)

^d Laxmi Pest and Fumigation Pvt Ltd   (India)

^e UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Benzopyrans; Negentropy; Potassium channel activators; QSAR; Topological indices

Indexed keywords

BENZOPYRAN DERIVATIVE; POTASSIUM CHANNEL STIMULATING AGENT; BRONCHODILATING AGENT; POTASSIUM CHANNEL;

ANIMAL TISSUE; ARTICLE; NONHUMAN; PREDICTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT; TRACHEA; VALIDATION PROCESS; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; DRUG EFFECT; METABOLISM; PREDICTION AND FORECASTING;

ANIMALS; BENZOPYRANS; BRONCHODILATOR AGENTS; MODELS, BIOLOGICAL; POTASSIUM CHANNELS; PREDICTIVE VALUE OF TESTS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RATS; TRACHEA;

EID: 33646478469     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2005.11.004     Document Type: Article

References (25)

1. Mannhold R., Cruciani G., Weber H., Lemoine H., Derix A., Weichel C., and Clementi M. J. Med. Chem. 42 (1999) 981-991
2. Agrawal V.K., Singh J., and Khadikar P.V. Bioorg. Med. Chem. 10 (2002) 3981-3996
3. Agrawal V.K., Sharma R., and Khadikar P.V. Bioorg. Med. Chem. 10 (2002) 2993-2999
4. Agrawal V.K., Sohgaura R., and Khadikar P.V. Bioorg. Med. Chem. 9 (2001) 3295-3299
5. Agrawal V.K., Bano S., Supuran C.T., and Khadikar P.V. Eur. J. Med. Chem. 39 (2004) 593-600
6. Agrawal V.K., Shrivastva S., and Khadikar P.V. Moecular Div. 8 (2004) 413-419
7. Agrawal V.K., Karmarkar S., Khadikar P.V., Shrivastva S., and Lukovits I. Ind. J. Chem. 42A (2003) 1426-1435
8. Khadikar P.V., Lukovits I., Agrawal V.K., Shrivastva S., Jaiswal M., Gutman I., Karmarkar S., and Shrivastava A. Ind. J. Chem. 42A (2003) 1436-1442
9. Agrawal V.K., and Khadikar P.V. Bioorg. Med. Chem. 10 (2002) 3517-3522
10. Agrawal V.K., Joseph S., Khadikar P.V., and Karmarkar S. Acta Pharm. 50 (2000) 329-338
11. Agrawal V.K., Mishra K., and Khadikar P.V. Oxidation Commun. 26 (2003) 14-21
12. Chaterjee S., Hadi A.S., and Price B. (2000), Wiley, New York (3rd Ed)
13. Balaban A.T. Chem. Phys. Lett. 89 (1982) 399-404
14. Wiener H. J. Am. Chem. Soc. 69 (1947) 17-20
15. Kier L.B., and Hall L.H. Molecular connectivity in structure-activity relationship, Wiley, New York, 1986. In: Kier L.B., and Hall L.H. (Eds). Molecular structure description (1999), Academic Press, New York
16. Kier L.B. J. Pharm. Sci. 69 (1980) 807-810
17. Randic M. Croat. Chem. Acta 66 (1993) 289-299
18. Khadikar P.V., Sharma S., Sharma V., Joshi S., Lukovits I., and Kaveeshwar M. Bull. Soc.Chem.Belg. 106 (1997) 767-772
19. Khadikar P.V., Deshpandey N.V., Kale P.P., Dubrynin A., Gutman I., and Domotor G.J. Chem. Inf. Comput. Sci. 35 (1995) 547-550
20. R. Todeschini, V. Consonni, Handbook of Molecular Descriptors, Wiley-VCH, Weinheim GER, 2000. M. Karelson, Molecular Descriptors in QSAR/QSPR, J. Wiley & Sons, New York, 2000. M.V. Diudea, Ed. QSPR/QSAR Studies by Molecular Descriptors, Babes-Bolyai University, Cluj. Romania, 2000. N. Trinajstic, Chemical Graph Theory, 2nd revised ed, CRC Press, Boca Raton, Fl, 1992.
21. Pogliani L. Amino Acids J. Phys. Chem. 98 (1994) 1494-1499
22. Pogliani L. Recent trends in graph theoretical descriptors. Chem. Rev. 100 (2000) 3827-3858
23. Devillers J., and Balaban A.T. Topological Indices and Related Descriptors in QSAR and QSPR (2000), Gorden & Breach, Williston, VT
24. Agrawal V.K., Bano S., and Khadikar P.V. Bioorg. Med. Chem. 13 (2003) 4039-4047
25. Khadikar P.V., Srivastava A., Agrawal V.K., and Shrivastava S. Bioorg. Med. Chem. Lett. 13 (2003) 3014-3020