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Volumn 71, Issue 5, 2006, Pages 364-370

Use of isotope ratio mass spectrometry to detect doping with oral testosterone undecanoate: Inter-individual variability of 13C/12C ratio

Author keywords

Doping control; Isotope ratio mass spectrometry (IRMS); Multiple administrations; Testosterone undecanoate (TU)

Indexed keywords

ANDROSTANE DERIVATIVE; ANDROSTERONE; CARBON; CARBON 13; DRUG METABOLITE; ETIOCHOLANOLONE; ISOTOPE; TESTOSTERONE UNDECANOATE;

EID: 33646468993     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2005.11.004     Document Type: Article
Times cited : (33)

References (22)
  • 1
    • 0030903971 scopus 로고    scopus 로고
    • Detection of anabolic steroid administration: ratio of urinary testosterone to epitestosterone vs the ratio of urinary testosterone to luteinizing hormone
    • Perry P.J., MacIndoe J.H., Yates W.R., Scott S.D., and Holman T.L. Detection of anabolic steroid administration: ratio of urinary testosterone to epitestosterone vs the ratio of urinary testosterone to luteinizing hormone. Clin Chem 43 (1997) 731-735
    • (1997) Clin Chem , vol.43 , pp. 731-735
    • Perry, P.J.1    MacIndoe, J.H.2    Yates, W.R.3    Scott, S.D.4    Holman, T.L.5
  • 2
    • 0026744043 scopus 로고
    • Detection of testosterone administration by increased ratio between serum concentrations of testosterone and 17α-hydroxyprogesterone
    • Carlström K., Palonek E., Garle M., Oftebro H., Stanghelle J., and Björkhem I. Detection of testosterone administration by increased ratio between serum concentrations of testosterone and 17α-hydroxyprogesterone. Clin Chem 38 (1992) 1779-1784
    • (1992) Clin Chem , vol.38 , pp. 1779-1784
    • Carlström, K.1    Palonek, E.2    Garle, M.3    Oftebro, H.4    Stanghelle, J.5    Björkhem, I.6
  • 3
    • 33646483713 scopus 로고    scopus 로고
    • WADA technical document: reporting and evaluation guidance for testosterone, epitestosterone, T/E ratio and other endogenous steroids; 2004. http://www.wada-ama.org.
  • 4
    • 0023251458 scopus 로고
    • Increasing circulating androgens with oral testosterone undecanoate in eugonadal men
    • Davidson D.W., O'Carroll R., and Bancroft J. Increasing circulating androgens with oral testosterone undecanoate in eugonadal men. J Steroids Biochem Mol Biol 26 (1987) 713-715
    • (1987) J Steroids Biochem Mol Biol , vol.26 , pp. 713-715
    • Davidson, D.W.1    O'Carroll, R.2    Bancroft, J.3
  • 5
    • 0027457943 scopus 로고
    • Comparison of plasma androgen glucuronide levels after percutaneous or peroral androgen treatment in men: evidence for important splanchnic contribution to plasma 17β-hydroxyandrogen glucuronides
    • Giagulli V.A., Verdonck L., Deslypere J.P., Giorgino R., and Vermeulen A. Comparison of plasma androgen glucuronide levels after percutaneous or peroral androgen treatment in men: evidence for important splanchnic contribution to plasma 17β-hydroxyandrogen glucuronides. J Clin Endocrinol Metab 76 (1993) 429-431
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 429-431
    • Giagulli, V.A.1    Verdonck, L.2    Deslypere, J.P.3    Giorgino, R.4    Vermeulen, A.5
  • 6
    • 0016742354 scopus 로고
    • Plasma androgen levels in men after oral administration of testosterone or testosterone undecaonate
    • Nieschlag E., Mauss J., Coert A., and Kićovic P. Plasma androgen levels in men after oral administration of testosterone or testosterone undecaonate. Acta Endocrinol 79 (1975) 366-374
    • (1975) Acta Endocrinol , vol.79 , pp. 366-374
    • Nieschlag, E.1    Mauss, J.2    Coert, A.3    Kićovic, P.4
  • 7
    • 0016749625 scopus 로고
    • The pharmacology and metabolism of testosterone undecanoate (TU), a new orally active androgen
    • Coert A., Geelen J., de Visser J., and van der Vies J. The pharmacology and metabolism of testosterone undecanoate (TU), a new orally active androgen. Acta Endocrinol 79 (1975) 789-800
    • (1975) Acta Endocrinol , vol.79 , pp. 789-800
    • Coert, A.1    Geelen, J.2    de Visser, J.3    van der Vies, J.4
  • 8
    • 0002517279 scopus 로고
    • Long term study of steroid and peptidic hormones in the plasma of healthy young men under controlled testosterone undecanoate therapy
    • Hemmersbach P., and Birkeland K.I. (Eds), Oslo, Pensumtjeneste
    • Wright F., Lafarge J.P., Antréassian J., Lagoguey M., and Pérès G. Long term study of steroid and peptidic hormones in the plasma of healthy young men under controlled testosterone undecanoate therapy. In: Hemmersbach P., and Birkeland K.I. (Eds). Blood samples for doping control (1994), Oslo, Pensumtjeneste 65-74
    • (1994) Blood samples for doping control , pp. 65-74
    • Wright, F.1    Lafarge, J.P.2    Antréassian, J.3    Lagoguey, M.4    Pérès, G.5
  • 9
    • 4344718394 scopus 로고    scopus 로고
    • Urinary analysis of four testosterone metabolites and pregnanediol by gas chromatography/combustion/isotope ratio mass spectrometry after oral administrations of testosterone
    • Maître A., Saudan C., Mangin P., and Saugy M. Urinary analysis of four testosterone metabolites and pregnanediol by gas chromatography/combustion/isotope ratio mass spectrometry after oral administrations of testosterone. J Anal Toxicol 28 (2004) 426-431
    • (2004) J Anal Toxicol , vol.28 , pp. 426-431
    • Maître, A.1    Saudan, C.2    Mangin, P.3    Saugy, M.4
  • 10
  • 12
    • 0027401767 scopus 로고
    • Long-term administration of testosterone enanthate to normal men: alterations of the urinary profile of androgen metabolites potentially useful for detection of testosterone misuse in sport
    • Dehennin L., and Matsumoto A.M. Long-term administration of testosterone enanthate to normal men: alterations of the urinary profile of androgen metabolites potentially useful for detection of testosterone misuse in sport. J Steroids Biochem Mol Biol 44 (1993) 179-189
    • (1993) J Steroids Biochem Mol Biol , vol.44 , pp. 179-189
    • Dehennin, L.1    Matsumoto, A.M.2
  • 13
    • 4444384256 scopus 로고    scopus 로고
    • Urinary analysis of 16(5α)-androsten-3α-ol by gas chromatography/combustion/isotope ratio mass spectrometry: implications in anti-doping analysis
    • Saudan C., Baume N., Mangin P., and Saugy M. Urinary analysis of 16(5α)-androsten-3α-ol by gas chromatography/combustion/isotope ratio mass spectrometry: implications in anti-doping analysis. J Chromatogr B 810 (2004) 157-164
    • (2004) J Chromatogr B , vol.810 , pp. 157-164
    • Saudan, C.1    Baume, N.2    Mangin, P.3    Saugy, M.4
  • 14
    • 0029784817 scopus 로고    scopus 로고
    • Plasma and urinary markers of oral testosterone misuse by healthy men in presence of masking epitestosterone administration
    • Dehennin L., and Peres G. Plasma and urinary markers of oral testosterone misuse by healthy men in presence of masking epitestosterone administration. Int J Sports Med 17 (1996) 315-319
    • (1996) Int J Sports Med , vol.17 , pp. 315-319
    • Dehennin, L.1    Peres, G.2
  • 15
    • 0031894377 scopus 로고    scopus 로고
    • The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268)
    • Coffman B.L., King C.D., Rios G.R., and Tephly T.R. The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268). Drug Metab Disp 26 (1998) 73-77
    • (1998) Drug Metab Disp , vol.26 , pp. 73-77
    • Coffman, B.L.1    King, C.D.2    Rios, G.R.3    Tephly, T.R.4
  • 17
    • 0030934910 scopus 로고    scopus 로고
    • Confirming testosterone administration by isotope ratio mass spectrometric analysis of urinary androstanediols
    • Shackleton CHL, Phillips A., Chang T., and Li Y. Confirming testosterone administration by isotope ratio mass spectrometric analysis of urinary androstanediols. Steroids 62 (1997) 379-387
    • (1997) Steroids , vol.62 , pp. 379-387
    • Shackleton CHL1    Phillips, A.2    Chang, T.3    Li, Y.4
  • 18
    • 14944343744 scopus 로고    scopus 로고
    • 12C isotope ratio of the hormones in bovine urine using gas chromatography/combustion/isotope ratio mass spectrometry
    • 12C isotope ratio of the hormones in bovine urine using gas chromatography/combustion/isotope ratio mass spectrometry. J Chromatogr A 1067 (2005) 323-330
    • (2005) J Chromatogr A , vol.1067 , pp. 323-330
    • Balizs, G.1    Jainz, A.2    Horvatovich, P.3
  • 19
    • 0035136380 scopus 로고    scopus 로고
    • Performance characteristics of a carbon isotope ratio method for detecting doping with testosterone based on urine diols: controls and athletes with elevated testosterone/epitestosterone ratios
    • Aguilera R., Chapman T.E., Starcevic B., Hatton C.K., and Catlin D.H. Performance characteristics of a carbon isotope ratio method for detecting doping with testosterone based on urine diols: controls and athletes with elevated testosterone/epitestosterone ratios. Clin Chem 47 (2001) 292-300
    • (2001) Clin Chem , vol.47 , pp. 292-300
    • Aguilera, R.1    Chapman, T.E.2    Starcevic, B.3    Hatton, C.K.4    Catlin, D.H.5
  • 21
    • 0034894699 scopus 로고    scopus 로고
    • Natural intramolecular isotope measurements in physiology: elements of the case for an effort toward high-precision position-specific isotope analysis
    • Brenna J.T. Natural intramolecular isotope measurements in physiology: elements of the case for an effort toward high-precision position-specific isotope analysis. Rapid Commun Spectrom 15 (2001) 1252-1262
    • (2001) Rapid Commun Spectrom , vol.15 , pp. 1252-1262
    • Brenna, J.T.1
  • 22
    • 0030746504 scopus 로고    scopus 로고
    • Electrospray mass spectrometry of testosterone esters: potential for use in doping control
    • Shackleton CHL, Chuang H., Kim J., de la Torre X., and Segura J. Electrospray mass spectrometry of testosterone esters: potential for use in doping control. Steroids 62 (1997) 523-529
    • (1997) Steroids , vol.62 , pp. 523-529
    • Shackleton CHL1    Chuang, H.2    Kim, J.3    de la Torre, X.4    Segura, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.