Confirming testosterone administration by isotope ratio mass spectrometric analysis of urinary androstanediols

Steroids

Volumn 62, Issue 4, 1997, Pages 379-387

  Shackleton, Cedric H L ^a   Phillips, Andy ^b   Chang, Tony ^a   Li, Ye ^c  

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^b MICROMASS UK LTD   (United Kingdom)

^c NATIONAL RESEARCH INSTITUTE FOR FAMILY PLANNING   (China)

Author keywords

doping control; isotope ratio mass spectrometry (IRMS); testosterone

Indexed keywords

ANDROSTANEDIOL; PREGNANEDIOL; TESTOSTERONE ENANTATE;

ADULT; ARTICLE; CHROMATOGRAPHY; DOPING; GAS CHROMATOGRAPHY; HORMONE DETERMINATION; HUMAN; HUMAN EXPERIMENT; ISOTOPE TRACING; MALE; MASS SPECTROMETRY; STEROID URINE LEVEL;

ADULT; ANDROSTANE-3,17-DIOL; ASIAN CONTINENTAL ANCESTRY GROUP; CHROMATOGRAPHY, GAS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CONTRACEPTIVE AGENTS, MALE; DIET; EPITESTOSTERONE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; ISOTOPES; MALE; PREGNANEDIOL; REPRODUCIBILITY OF RESULTS; TESTOSTERONE;

EID: 0030934910     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-128X(96)00253-X     Document Type: Article

References (12)

1. Catlin DH, Cowan DA, De la Torre R, Donike M, Fraisse D, Oftegro H, Hatton CK, Starcevic B, Becchi M, de la Torre X, Norli H, Geyer H, Walker CJ (1996). Urinary testosterone (T) to epitestosterone (E) ratios by GC/MS. I. Initial comparison of uncorrected T/E in six international laboratories. J Mass Spectrom 31:397-402.
2. Southan G, Mallet A, Jumeau J, Craig S, Poojara N, Mitchell D, Wheeler M, Brooks RV (1990). Programme and Abstracts of The 2nd International Symposium on Applied Mass Spectrometry in the Health Sciences, Barcelona, Spain, p. 306.
3. 12C ratios for higher plants. Plant Physiol 47:380-384.
4. Becchi M, Aguilera R, Farizon Y, Flament IM-M, Casabianca H, James P (1994). Gas chromatography/combustion/isotope-ratio mass spectrometry analysis of urinary steroids to detect misuse of testosterone in sport. Rapid Commun Mass Spectrom 8:301-308.
5. Aguilera R, Becchi M, Casabianca H, Hatton CK, Catlin DH, Starcevic B, Pope JHG (1996). Improved method of detection of testosterone abuse by gas chromatography/combustion/isotope ratio mass spectrometry analysis of urinary steroids, J. Mass Spectrom 31:169-176.
6. Donike M, Bärwald KR, Klosterman K, Schänzer W, Zimmerman J (1983). Sport. Leistung und Gesundheit, Cologne, Germany, p. 293.
7. Shackleton CHL, Whitney JO (1980). Use of Sep-pak® cartridges for urinary steroids extraction: Evaluation of the method for use prior to gas chromatographic analysis. Clin Chim Acta 107:231-243.
8. Girard A, Sandulesco G (1936). Sur une nouvelle série de réactif du groupe carbonyle, leur utilisation à l'extraction des substances cétoniques et à la characterisation microchinique des aldéhydes et cétones. Helv Chim Acta 19:1095-1107.
9. Bush IE (1961). The Chromatography of Steroids. Pergamon Press Ltd., Oxford, UK, pp. 358-371.
10. Setchell KDR, Shackleton CHL (1973). The group separation of plasma and urinary steroids by column chromatography on Sephadex LH-20. Clin Chim Acta 47:381-388.
11. de la Torre X, Segura J, Farré M, Yang Z, Li Y, Wu M (1995). Steroid profile in different ethnic groups after testosterone ethanate administration. In: Donike M, Geyer H, Gotzmann A, Mareck-Engelke U (eds), Recent Advances in Doping Analysis. Sport und Buch Strauß, Köln, Germany, pp. 59-80.
12. Shackleton CHL, Honour JW (1976). Simultaneous estimation of urinary steroids by semiautomated gas chromatography. Investigation of neonatal infants and children with abnormal steroid synthesis. Clin Chim Acta 69:267-283.