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Volumn 29, Issue 3, 2006, Pages 191-194

Acyl-CoA: Cholesterol acyltransferase inhibitors from Ilex macropoda

Author keywords

ACAT inhibitory activity; Betulin; Ilex macropoda; Lupeol

Indexed keywords

BETULIN; CHOLESTEROL ACYLTRANSFERASE; ENZYME INHIBITOR; HYPOCHOLESTEROLEMIC AGENT; LUPEOL; PLANT EXTRACT; STEROL O ACYLTRANSFERASE 1; STEROL O ACYLTRANSFERASE 2; STEROL O-ACYLTRANSFERASE 1; STEROL O-ACYLTRANSFERASE 2; TRITERPENE;

EID: 33646468968     PISSN: 02536269     EISSN: 02536269     Source Type: Journal    
DOI: 10.1007/BF02969391     Document Type: Article
Times cited : (12)

References (16)
  • 2
    • 0032500649 scopus 로고    scopus 로고
    • Identification of a form of acyl-CoA: Cholesterol acyltransferase specific to liver and intestine in nonhuman primates
    • Anderson, R. A., Joyce, C., Davis, M., Reagan, J. W., Clark, M., Shelness, G. S., and Rudel, L. L., Identification of a form of acyl-CoA: cholesterol acyltransferase specific to liver and intestine in nonhuman primates. J. Biol. Chem., 273, 26747-26754 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 26747-26754
    • Anderson, R.A.1    Joyce, C.2    Davis, M.3    Reagan, J.W.4    Clark, M.5    Shelness, G.S.6    Rudel, L.L.7
  • 3
    • 0016691608 scopus 로고
    • Cholesterol ester formation in cultured human fibroblasts
    • Brown, M. S., Dana, S. E., and Goldstein, J. L., Cholesterol ester formation in cultured human fibroblasts. J. Biol. Chem., 250, 4025-4027 (1975).
    • (1975) J. Biol. Chem. , vol.250 , pp. 4025-4027
    • Brown, M.S.1    Dana, S.E.2    Goldstein, J.L.3
  • 5
    • 0001225155 scopus 로고
    • The formation of cholesterol esters with rat liver enzymes
    • Goodman, D. S., Deykin, D., and Shiratori, T., The formation of cholesterol esters with rat liver enzymes. J. Biol. Chem., 239, 1335-1345 (1964).
    • (1964) J. Biol. Chem. , vol.239 , pp. 1335-1345
    • Goodman, D.S.1    Deykin, D.2    Shiratori, T.3
  • 6
    • 0017837059 scopus 로고
    • Studies on the constituents of Marsdenia formosana Masamune. I. Isolation of tirterpenoids and structure of marsformal
    • Ito, K. and Lai, J., Studies on the constituents of Marsdenia formosana Masamune. I. Isolation of tirterpenoids and structure of marsformal. Yakugaku Zasshi, 98, 249-256 (1978).
    • (1978) Yakugaku Zasshi , vol.98 , pp. 249-256
    • Ito, K.1    Lai, J.2
  • 7
    • 3042838346 scopus 로고    scopus 로고
    • Inhibitory effects of multi-substituted benzylidenzethiazolidine-2,4- diones on LDL oxidation
    • Jeong, T. S., Kim, J. R., Kim, K. S., Cho, K. H., Bae, K. H., and Lee, W. S., Inhibitory effects of multi-substituted benzylidenzethiazolidine-2,4-diones on LDL oxidation. Bioorg. Med. Chem., 12, 4017-4023 (2004).
    • (2004) Bioorg. Med. Chem. , vol.12 , pp. 4017-4023
    • Jeong, T.S.1    Kim, J.R.2    Kim, K.S.3    Cho, K.H.4    Bae, K.H.5    Lee, W.S.6
  • 8
    • 0033739779 scopus 로고    scopus 로고
    • ACAT1 and ACAT2 membrane topology segregates a serine residue essential for activity to opposite sides of the endopasmic reticulum membrane
    • Joyce, C. W., Sheiness, G. S., Davis, M. A., Lee, R. G., Skinner, K., Anderson, R. A., and Rudel, L. L., ACAT1 and ACAT2 membrane topology segregates a serine residue essential for activity to opposite sides of the endopasmic reticulum membrane. Mol. Biol. Cell, 11, 3675-3687 (2000).
    • (2000) Mol. Biol. Cell , vol.11 , pp. 3675-3687
    • Joyce, C.W.1    Sheiness, G.S.2    Davis, M.A.3    Lee, R.G.4    Skinner, K.5    Anderson, R.A.6    Rudel, L.L.7
  • 10
    • 0028280316 scopus 로고
    • Pyripyropenes, novel inhibitors of acyl-CoA: Cholesterol acyltransferase produced by Aspergillus fumigatus
    • Kim, Y. K., Tomoda, H., and Nishida, H., Pyripyropenes, novel inhibitors of acyl-CoA: Cholesterol acyltransferase produced by Aspergillus fumigatus. J. Antibiot., 47, 154-162 (1994).
    • (1994) J. Antibiot. , vol.47 , pp. 154-162
    • Kim, Y.K.1    Tomoda, H.2    Nishida, H.3
  • 11
    • 0034813893 scopus 로고    scopus 로고
    • Anti-atherogenic effect of citrus flavonoids, naringin and naringenin, associated with hepatic ACAT and aortic VCAM-1 and MCP-1 in high cholesterol-fed rabbits
    • Lee, C. H., Jeong, T. S., Choi, Y. K., Hyun, B. W., Oh, G. T., Kim, E. H., Kim. J. R., Han, J. I., and Bok, S. H., Anti-atherogenic effect of citrus flavonoids, naringin and naringenin, associated with hepatic ACAT and aortic VCAM-1 and MCP-1 in high cholesterol-fed rabbits. Biochem. Biophys. Res. Commun., 284, 681-688 (2001).
    • (2001) Biochem. Biophys. Res. Commun. , vol.284 , pp. 681-688
    • Lee, C.H.1    Jeong, T.S.2    Choi, Y.K.3    Hyun, B.W.4    Oh, G.T.5    Kim, E.H.6    Kim, J.R.7    Han, J.I.8    Bok, S.H.9
  • 12
    • 25144476179 scopus 로고    scopus 로고
    • Potential role of acylcoenzyme A: Cholesterol transferase (ACAT) inhibitors as hypolipidemic and antiatherosclerosis drugs
    • Leon, C., Hill, J. S., and Wasan, K. M., Potential role of acylcoenzyme A: cholesterol transferase (ACAT) inhibitors as hypolipidemic and antiatherosclerosis drugs. Pharm Res., 10, 1578-1588 (2005).
    • (2005) Pharm Res. , vol.10 , pp. 1578-1588
    • Leon, C.1    Hill, J.S.2    Wasan, K.M.3
  • 14
    • 0026668238 scopus 로고
    • Inhibitors of acyl-CoA:cholesterol acyltransferase. 1. Identification and structureactivity relationships of a novel series of fatty acid anillide hypocholesterolemic agents
    • Roth, B. D., Blankley, J., and Hoefle, M. L., Inhibitors of acyl-CoA:cholesterol acyltransferase. 1. Identification and structureactivity relationships of a novel series of fatty acid anillide hypocholesterolemic agents. J. Med. Chem., 35, 1609-1617 (1992).
    • (1992) J. Med. Chem. , vol.35 , pp. 1609-1617
    • Roth, B.D.1    Blankley, J.2    Hoefle, M.L.3
  • 15
    • 0035081589 scopus 로고    scopus 로고
    • Acyl coenzyme A: Cholesterol acyltransferase types 1 and 2: Structure and function in atherosclerosis
    • Rudel, L. I., Lee, R. G., and Cockman, T. L., Acyl coenzyme A: cholesterol acyltransferase types 1 and 2: structure and function in atherosclerosis. Curr. Opin. Lipidol., 12, 121-127 (2001).
    • (2001) Curr. Opin. Lipidol. , vol.12 , pp. 121-127
    • Rudel, L.I.1    Lee, R.G.2    Cockman, T.L.3
  • 16
    • 33845279415 scopus 로고
    • Oleanderol, a new pentacyclic triterpene from the leaves of Nerium oleander
    • Siddiqui, S., Hafeez, F., Begum, S., and Siddiqui, B. S., Oleanderol, a new pentacyclic triterpene from the leaves of Nerium oleander. J. Nat. Prod., 51, 229-233 (1988).
    • (1988) J. Nat. Prod. , vol.51 , pp. 229-233
    • Siddiqui, S.1    Hafeez, F.2    Begum, S.3    Siddiqui, B.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.