Altered synemin could affect the organization of intermediate filament in human hepatocellular carcinoma

Journal of Medicine

Volumn 35, Issue 1-6, 2004, Pages 171-180

  Ho, Chin Chin ^a   Ho, Heng Chien ^a   Liu, Yi Hsiang ^a,b   Pei, Ren Jeng ^a,b   Cheng, Chiung Chi ^a   Lee, Karen Ying ^a,b   Yeh, Kun Tu ^a,c   Lai, Yih Shyong ^a,d  

^a CHUNGTAI INST HLTH SCI TECHNOL   (Taiwan)

^b JEN AI HOSPITAL   (Taiwan)

^c CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^d CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Altered synemin; Carcinoma; Filament bundles; Filaments; Hepatocellular carcinoma; Liver cells; Tumorigenesis

Indexed keywords

INTERMEDIATE FILAMENT PROTEIN; SYNEMIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CARCINOGENESIS; CELL SHAPE; CELL STRUCTURE; CONTROLLED STUDY; CYTOARCHITECTURE; CYTOSKELETON; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTERMEDIATE FILAMENT; LIVER CELL CARCINOMA; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION;

CARCINOMA, HEPATOCELLULAR; CYTOSKELETON; HEPATOCYTES; HUMANS; INTERMEDIATE FILAMENT PROTEINS; INTERMEDIATE FILAMENTS; KERATIN-18; LIVER NEOPLASMS;

EID: 33646455695     PISSN: 00257850     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Anne, L., Sophie, D., Andree, G., Jennifer, P., Marcia, W-H., Helene, B. and Normand, M. (1997) Simple epithelium keratins are required for maintenance of hepatocyte integrity. Am. J. Pathol., 151:1673-1683.
2. Asch, H.L., Head, K., Dong, Y., Natoli, F., Winston, J.S., Connolly, J.L. and Asch, B.B. (1996) Widespread loss of gelsolin in breast cancers of humans, mice and rats. Cancer Res., 56:4841-4845.
3. Bellin, R.M., Sernett, S.W., Becker, B., Ip, W., Huiatt, T.W. and Robson, R.M. (1999) Molecular characteristics and interactions of the intermediate filament protein synemin. J. Biol. Chem., 274:29493-29499.
4. Bilak, S.R., Sernett, S.W., Bilak, M.M., Bellin, R.M., Stromer, M.H., Huiatt, T.W. and Robson, R.M. (1998) Properties of the novel intermediate filament protein synemin and its identification in mammalian muscle. Arch. Biochem. Biophys., 355(1):63-76.
5. Bonne, G., Di Barletta, M.R., Varnous, S., Becane, H.M., Hammouda, E.H., Merlini, L., Muntoni, F., Greeberg, C.R., Gary, F., Urtizberea, J.A., Duboc, D., Fardeau, M., Toniolo, D. and Schwartz, K. (1999) Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreyfuss muscular dystrophy. Nat. Genet., 21:285-288.
6. Chakraborty, J. and von Stein, G.A. (1986) Pleomorphism of human prostates cancer cells (DU145) in culture - The role of cytoskeleton. Exp. Mol. Pathol., 44:235-245.
7. Crowe, D.L., Milo, G.E. and Shuler, C.F. (1999) Keratin 19 down regulation by oral squamous cell carcinoma lines increases invasive potential. J. Dent. Res., 78:1256-1263.
8. Feldmann, G. (1989) The cytoskeleton of the hepatocytes. Structure and functions. J. Hepatol., 8:380-386.
9. Fuchs, E. and Clevel, D.W. (1998) A structural scaffolding of intermediate filament in health and disease. Science, 279:514-519.
10. Granger, B.L. and Lazarides, E. (1982) Structural associations of synemin and vimentin filaments in avian erythrocytes revealed by immunoelectron microscopy. Cell, 30(1):263-275.Granger,
11. B.L. and Lazarides, E. (1980) Synemin a new high molecular weight protein associated with desmin and vimentin filaments in muscle. Cell, 22:727-738.
12. Hsu, S.M., Raine, L. and Fanger, H. (1981) Use of avidin-biotin- peroxidase complex (ABC) in immunoperoxidase techniques. J. Histochem. Cytochem., 29:577-580.
13. Katsuma, Y., Marceau, N., Ohta, M. and French, S.W. (1988) Cytokeratin intermediate filaments of rat hepatocytes: Different cytoskeletal domains and their 3-dimensional structure. Hepatol., 8:559-568.
14. Lazarides, E. (1980) Intermediate filaments as mechanical integrators of cellular space. Nature, 283:249.
15. Liu, Y.H., Su, B.S., Pei, R.J., Yeh, C.C., Yeh, K.T., Lee, K.Y., Hsu, Y.H., Ho, C.C. and Lai Y.H. (2001) Stability of cytokeratin18 in human liver cells during colchicines induced microtubule disruption. Food Chemical Toxicol., 39:85-89.
16. Moll, R., Franke, W.W. and Schiller, D.A. (1982) The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells. Cell, 31:11.
17. Montse, O., Lev, G., Ayush, D., Nyamkhishig, S., Denise, P., Zhenlin, L., Bertrand, G., Patrick, V. and Isidro, F. (2003) Expression of the intermediate filament protein synemin in myofibrillar myopathies and other muscle diseases. Acta Neuropatho., 106:1-7.
18. Muchir, A., Bonne, G., van der Kooi, A.J., Meegen, M., van Baas, F., Bolhuis, P.A.,Visser, M., and de Schwartz, K.(2000) Identification of mutations in the gene encoding lamins A/C in autosomal dominant limb girdle muscular dystrophy with atrioventricular conduction disturbances (LGMD 1B). Hum. Mol. Genet., 9:1453-1459.
19. Munoz-Marmol, A.M., Stasser, G., Isamat, M., Coulombre, P.A.,Yang, Y., Roca, X., Vela, E., Mate, J.L., Coll, J., Fernanddez-Figueras, M.T., Navas-Palacaios, J.J., Ariza, A. and Fuchs, E. (1998) A dysfunctional desmin mutation in a patient with severe generalized myopathy. Proc. Natl. Acad. Sci. U.S.A., 95:11312-11317.
20. Olive, M., Goldfarb, L., Dagvadorj, A., Sambuuhin, N., Paulin, D., Li, Z., Goudeau, B., Vicart, P. and Ferrer, I. (2003) Expression of the intermediate filament protein synemin in myofibrillar myopathies and other muscle diseases. Acta. Neuropatho., 106:1-7.
21. Omary, M.B. and Ku, N.O. (1997) Intermediate filament proteins of the liver: emerging disease association and function. Hepatol., 25:1043-1048.
22. Price, M.G. and Lazarides, E. (1983) Expression of intermediate filament-associated proteins paranemin and synemin in chicken development. J. Cell. Biol., 97:1860-1874.
23. Robson, R.M. (1989) Intermediate filaments. Curr. Opin. Cell. Biol., 1(1):36-43.
24. Smith, F.J.D., Eady, R.A.J., Leigh, I.M., McMillan, J.R., Rugg, E.L., Kelsell, D.P., Bryant, S.P., Spurr, N.K., Geddes, J.F., Kirtschig, G., Milana, G., de Bono, A.G., Owaribe, K., Wiche, G., Pulkkinen, L., Uitto, J., McLean, W.H.I. and Lane, E.B. (1996) Plectin deficiency results in muscular dystrophy with epidermolysis bullosa. Nat. Genet., 13(4):450-457.
25. Sultana, S., Sernette, S.W., Bellin, R.M., Robson, R.M. and Skalli, O. (2000) Intermediate filament protein synemin is transiently expressed in a subset of astrocytes during development. Glia, 30:143-153.
26. Svitkina, T.M., Verkhovsky, A.B. and Borisy, G.G. (1996) Plectin side arms mediate interaction of intermediate filaments with microtubules and other components of cytoskeleton. J. Cell Biol., 135:991-1007.
27. Van Eyken, P. and Desmet, V.J. (1993) Cytokeratins and the liver. Liver, 13:113-122.