Virucidal activity of a GT-rich oligonucleotide against herpes simplex virus mediated by glycoprotein B

Journal of Virology

Volumn 80, Issue 10, 2006, Pages 4740-4747

  Shogan, Benjamin ^a,b   Kruse, Lori ^a,c   Mulamba, Gilbert B ^a,d   Hu, André ^a,e   Coen, Donald M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^c CAROLINAS MEDICAL CENTER   (United States)

^d Reconstructive Orthopedics PA ^*  (United States)

^e Reconstructive Orthopedics PA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FOMIVIRSEN; GLYCOPROTEIN B; GT RICH OLIGONUCLEOTIDE; GUANOSINE; ISIS 5652; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; OLIGONUCLEOTIDE; THYMINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG RESISTANCE; GENE MUTATION; HERPES SIMPLEX VIRUS; NONHUMAN; PLAQUE REDUCTION ASSAY; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TEMPERATURE; UL27 GENE; VIRUS ADSORPTION; VIRUS CELL INTERACTION; VIRUS CULTURE; VIRUS ENTRY; VIRUS GENE; VIRUS INFECTIVITY; VIRUS MUTANT;

ANIMALS; ANTIVIRAL AGENTS; CERCOPITHECUS AETHIOPS; DINUCLEOTIDE REPEATS; DRUG RESISTANCE, VIRAL; GUANINE; MUTATION; OLIGONUCLEOTIDES; SIMPLEXVIRUS; THIONUCLEOTIDES; THYMINE; TIME FACTORS; VERO CELLS; VIRAL ENVELOPE PROTEINS;

ANIMALIA; SIMPLEXVIRUS;

EID: 33646443203     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.80.10.4740-4747.2006     Document Type: Article

References (36)

1. Aguilar, J. S., M. Rice, and E. K. Wagner. 1999. The polysulfonated compound suramin blocks adsorption and lateral diffusion of herpes simplex virus type-1 in Vero cells. Virology 258:141-151.
2. Anderson, K. P., M. C. Fox, V. Brown-Driver, M. J. Martin, and R. F. Azad. 1996. Inhibition of human cytomegalovirus immediate-early gene expression by an antisense oligonucleotide complementary to immediate-early RNA. Antimicrob. Agents Chemother. 40:2004-2011.
3. Azad, R. F., V. B. Driver, K. Tanaka, R. M. Crooke, and K. P. Anderson. 1993. Antiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early region. Antimicrob. Agents Chemother. 37:1945-1954.
4. Biron, K. K., J. A. Fyfe, S. C. Stanat, L. K. Leslie, J. B. Sorrell, C. U. Lambe, and D. M. Coen. 1986. A human cytomegalovirus mutant resistant to the nucleoside analog, 9-[(2-hydroxy-1-(hydroxymethyl)ethoxy)methyl]guanine (BW B759U) induces reduced levels of BW B759U triphosphate. Proc. Natl. Acad. Sci. USA 83:8769-8773.
5. Bzik, D. J., B. A. Fox, N. A. DeLuca, and S. Person. 1984. Nucleotide sequence of a region of the herpes simplex virus type 1 gB glycoprotein gene: mutations affecting rate of virus entry and cell fusion. Virology 137:185-190.
6. Cai, W., S. Person, C. DebRoy, and B. Gu. 1988. Functional regions and structural features of the gB glycoprotein of herpes simplex virus type 1: an analysis of linker insertion mutants. J. Mol. Biol. 201:575-588.
7. Celum, C., R. Levine, M. Weaver, and A. Wald. 2004. Genital herpes and human immunodeficiency virus: double trouble. Bull. WHO 82:447-453.
8. Coen, D. M. 1991. The implications of resistance to antiviral agents for herpesvirus drug targets and drug therapy. Antivir. Res. 15:287-300.
9. Coen, D. M., H. E. Fleming, Jr., L. K. Leslie, and M. J. Retondo. 1985. Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locus. J. Virol. 53:477-488.
10. Cunningham, C., and A. J. Davison. 1993. A cosmid-based system for constructing mutants of herpes simplex virus type 1. Virology 197:116-124.
11. Desai, P., F. L. Homa, S. Person, and J. C. Glorioso. 1994. A genetic selection method for the transfer of HSV-1 glycoprotein mutations from plasmid to the viral genome: preliminary characterization of transdominance and entry kinetics of mutant viruses. Virology 204:312-322.
12. Esté, J. A., C. Cabrera, D. Schols, P. Cherepanov, A. Gutierrez, M. Witvrouw, C. Pannecouque, Z. Debyser, R. F. Rando, B. Clotet, J. Desmyter, and E. De Clercq. 1998. Human immunodeficiency virus glycoprotein gp120 as the primary target for the antiviral activity of AR177 (Zintevir). Mol. Pharmacol. 53:340-345.
13. Fennewald, S. M., S. Mustain, J. Ojwang, and R. F. Rando. 1995. Inhibition of herpes simplex virus in culture by oligonuclcotides composed entirely of deoxyguanosine and thymidine. Antivir. Res. 26:37-54.
14. Harrison, S. C. 2001. Principles of virus structure, p. 53-85. In D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, M. A. Martin, B. Roizman, and S. E. Straus (ed.), Fields virology, 4th ed. Lippincott Williams & Wilkins, Philadelphia, Pa.
15. Highlander, S. L., D. J. Dorney, P. J. Gage, T. C. Holland, W. Cai, S. Person, M. Levine, and J. C. Glorioso. 1989. Identification of mar mutations in herpes simplex virus type I glycoprotein B which alter antigenic structure and function in virus penetration. J. Virol. 63:730-738.
16. Highlander, S. L., W. F. Coins, S. Person, T. C. Holland, M. Levine, and J. C. Glorioso. 1991. Oligomer formation of the gB glycoprotein of herpes simplex virus type 1. J. Virol. 65:4275-4283.
17. Laquerre, S., R. Argnani, D. B. Anderson, S. Zucchini, R. Manservigi, and J. C. Glorioso. 1998. Heparan sulfate protcoglycan binding by herpes simplex virus type 1 glycoproteins B and C, which differ in their contributions to virus attachment, penetration, and cell-to-cell spread. J. Virol. 72:6119-6130.
18. MacLean, A. R. 1998. Preparation of HSV-DNA and production of infectious virus, p. 19-25. In S. M. Brown and A. R. MacLean (ed.), Herpes simplex virus protocols. Humana Press, Totowa, N.J.
19. MacLean, C. A. 1998. HSV entry and spread, p. 9-18. In S. M. Brown and A. R. MacLean (ed.), Herpes simplex virus protocols. Humana Press, Totowa, N.J.
20. McGeoch, D. J., M. A. Dalrymple, A. J. Davison, A. Dolan, M. C. Frame, D. McNab, L. J. Perry, J. E. Scott, and P. Taylor. 1988. The complete DNA sequence of the long unique region in the genome of herpes simplex virus type I. J. Gen. Virol. 69:1531-1574.
21. Mulamba, G. B., A. Hu, R. F. Azad, K. P. Anderson, and D. M. Coen. 1998. Human cytomegalovirus mutant with sequence-dependent resistance to the phosphorothioate oligonuclcotide fomiversen (ISlS 2922). Antimicrob. Agents Chemother. 42:971-973.
22. Nahmias, A. J., and S. Kihrick. 1964. Inhibitory effect of heparin on herpes simplex virus. J. Bacteriol. 87:1060-1066.
23. Ojwang, J. O., R. W. Buckheit, Y. Pommier, A. Mazumder, K. De Vreese, J. A. Esté, D. Reymen, L. A. Pallansch, C. Lackman-Smith, T. L. Wallace, E. De Clercq, M. S. McGrath, and R. F. Rando. 1995. T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1. Antimicrob. Agents Chemother. 39:2426-2435.
24. Parris, D. S., R. A. F. Dixon, and P. A. Schaffer. 1980. Physical mapping of herpes simplex virus type 1 ts mutants by marker rescue: correlation of the physical and genetic maps. Virology 100:275-287.
25. Roizman, B., and D. M. Knipe. 2001. Herpes simplex viruses and their replication, p. 2399-2459. In D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, M. A. Martin, B. Roizman, and S. E. Straus (ed.), Fields virology, 4th ed. Lippincott Williams & Wilkins, Philadelphia, Pa.
26. Shafer, R. H., and I. Smirnov. 2001. Biological aspects of DNA/RNA qua-druplexes. Biopolymers 56:209-227.
27. Shukla, D., and P. G. Spear. 2001. Herpesviruses and hcparan sulfate: an intimate relationship in aid of viral entry. J. Clin. Investig. 108:503-510.
28. Spear, P. G. 1993. Entry of alphaherpesviruscs into cells. Semin. Virol. 4:167-180.
29. Spear, P. G., and R. Longnecker. 2003. Herpesvirus entry: an update. J. Virol. 77:10179-10185.
30. Sullivan, V., and D. M. Coen. 1991. Isolation of foscarnet-resistant human cytomegalovirus: patterns of resistance and sensitivity to other antiviral drugs. J. Infect. Dis. 164:781-784.
31. Tondelli, L., F. P. Colonna, A. Garbesi, S. Zanella, M. E. Marongiu, S. Corrias, A. G. Loi, and P. La Colla. 1996. Native oligodeoxynucleotidcs specifically active against human immunodeficiency virus type 1 in vitro: a G-quartet-driven effect? Antimicrob. Agents Chemother. 40:2034-2038.
32. Whitley, R. J. 2001. Herpes simplex viruses, p. 2461-2509. In D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, M. A. Martin, B. Roizman, and S. E. Straus (ed.), Fields virology, 4th ed. Lippincott Williams & Wilkins, Philadelphia, Pa.
33. Williamson, J. R. 1994. G-quartet structures in tclomeric DNA. Annu. Rev. Biophys. Biomol. Struct. 23:703-730.
34. WuDunn, D., and P. G. Spear. 1989. Initial interaction of herpes simplex virus with cells is binding to heparan sulfate. J. Virol. 63:52-58.
35. Wyatt, J. R., T. A. Vickers, J. L. Roberson, R. W. J. Buckheit, T. Klimkait, E. DeBaets, P. W. Davis, B. Rayner, J. L. Imbach, and D. J. Ecker. 1994. Combinatorially selected guanosine-quartet structure is a potent inhibitor of human immunodeficiency virus envelope-mediated cell fusion. Proc. Natl. Acad. Sci. USA 91:1356-1360.
36. Young, J. A. T. 2001. Virus entry and uncoating, p. 87-103. In D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, M. A. Martin, B. Roizman, and S. E. Straus (ed.), Fields virology, 4th ed. Lippincott Williams & Wilkins, Philadelphia, Pa.