Highly skewed X-chromosome inactivation is associated with idiopathic reccurent spontaneous abortion [3]

American Journal of Human Genetics

Volumn 65, Issue 1, 1999, Pages 252-254

  Lanasa, M C ^a   Hogge, W A ^a   Kubik, C ^a   Blancato, J ^a   Hoffman, E P ^a  

^a CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL ARTICLE; FEMALE; GENETIC HETEROGENEITY; HEREDITY; HETEROZYGOTE; HUMAN; IDIOPATHIC DISEASE; LETTER; PHENOTYPE; PRIORITY JOURNAL; RECURRENT ABORTION; X CHROMOSOME INACTIVATION;

EID: 0033358729     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/302441     Document Type: Letter

References (10)

1. JW Belmont Genetic control of X inactivation and processes leading to X-inactivation skewing Am J Hum Genet 58 1996 1101 1108
2. L Busque R Mio J Mattioli E Brais N Blais Y Lalonde M Maragh Nonrandom X-inactivation patterns in normal females: lyonization ratios vary with age Blood 88 1996 59 65
3. RE Gale AK Fielding CN Harrison DC Linch Acquired skewing of X-chromosome inactivation patterns in myeloid cells of the elderly suggests stochastic clonal loss with age Br J Haematol 98 1997 512 519
4. HH Hatasaka Recurrent miscarriage: epidemiologic factors, definitions, and incidence Clin Obstet Gynecol 37 1994 625 634
5. F Motulsky AG Vogel Human genetics: problems and approaches 1997 Springer-Verlag Berlin
6. AK Naumova RM Plenge LM Bird M Leppert K Morgan HF Willard C Sapienza Heritability of X chromosome-inactivation phenotype in a large family Am J Hum Genet 58 1996 1111 1119
7. E Pegoraro RN Schimke K Arahata Y Hayashi H Stern H Marks MR Glasberg Detection of new paternal dystrophin gene mutations in isolated cases of dystrophinopathy in females Am J Hum Genet 54 1994 989 1003
8. E Pegoraro J Whitaker P Mowery-Rushton U Surti M Lanasa EP Hoffman Familial skewed X inactivation: a molecular trait associated with high spontaneous-abortion rate maps to Xq28 Am J Hum Genet 61 1997 160 170
9. RM Plenge BD Hendrich C Schwartz JF Arena A Naumova C Sapienza RM Winter A promoter mutation in the XIST gene in two unrelated families with skewed X-chromosome inactivation Nat Genet 17 1997 353 356
10. MD Stephenson Frequency of factors associated with habitual abortion in 197 couples Fertil Steril 66 1996 24 29