Enhancement of substrate-gated Cl- currents via rat glutamate transporter EAAT4 by PMA

American Journal of Physiology - Cell Physiology

Volumn 290, Issue 5, 2006, Pages

  Fang, Hongyu ^a   Huang, Yueming ^a   Zuo, Zhiyi ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

Oocytes; Protein kinase C

Indexed keywords

CALPHOSTIN C; CHELERYTHRINE; EXCITATORY AMINO ACID TRANSPORTER; GLUTAMATE TRANSPORTER; STAUROSPORINE;

ARTICLE; CEREBELLUM; CHLORIDE CONDUCTANCE; CHLORIDE CURRENT; EXTRACELLULAR FLUID; MEMBRANE POTENTIAL; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RAT; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; CELLS, CULTURED; CHLORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID TRANSPORTER 4; GLUTAMATE PLASMA MEMBRANE TRANSPORT PROTEINS; ION CHANNEL GATING; MEMBRANE POTENTIALS; OOCYTES; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; TETRADECANOYLPHORBOL ACETATE; XENOPUS LAEVIS;

EID: 33646429234     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00443.2005     Document Type: Article

References (48)

1. Arriza JL, Eliasof S, Kavanaugh MP, and Amara SG. Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance. Proc Natl Acad Sci USA 94: 4155-4160, 1997.
2. Arriza JL, Fairman WA, Wadiche JI, Murdoch GH, Kavanaugh MP, and Amara SG. Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex. J Neurosci 14: 5559-5569, 1994.
3. Barbour B, Keller BU, Llano I, and Marty A. Prolonged presence of glutamate during excitatory synaptic transmission to cerebellar Purkinje cells. Neuron 12: 1331-1343, 1994.
4. Barish ME. A transient calcium-dependent chloride current in the immature Xenopus oocyte. J Physiol 342: 309-325, 1983.
5. Billups B, Rossi D, Oshima T, Warr O, Takahashi M, Sarantis M, Szatkowski M, and Attwell D. Physiological and pathological operation of glutamate transporters. Prog Brain Res 116: 45-57, 1998.
6. Casado M, Bendahan A, Zafra F, Danbolt NC, Aragon C, Gimenez C, and Kanner BI. Phosphorylation and modulation of brain glutamate transporters by protein kinase C. J Biol Chem 268: 27313-27317, 1993.
7. Castagna M, Takai Y, Kaibuchi K, Sano K, Kikkawa U, and Nishizuka Y. Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. J Biol Chem 257: 7847-7851, 1982.
8. Conradt M and Stoffel W. Inhibition of the high-affinity brain glutamate transporter GLAST-1 via direct phosphorylation. J Neurochem 68: 1244-1251, 1997.
9. Costa PF, Emilio MG, Fernandez PL, and Ferreira KG. Determination of ionic permeability coefficients of the plasma membrane of Xenopus laevis oocytes under voltage clamp. J Physiol 483: 199-211, 1989.
10. Danbolt NC. Glutamate uptake. Prog Neurobiol 65: 1-105, 2001.
11. Dascal N. The use of Xenopus oocytes for the study of ion channels. Crit Rev Biochem 22: 317-387, 1987.
12. DeCoursey TE and Cherney VV. Voltage-activated hydrogen ion currents. J Membr Biol 141: 203-223, 1994.
13. Dempsey EC, Newton AC, Mochly-Rosen D, Fields AP, Reyland ME, Insel PA, and Messing RO. Protein kinase C isozymes and the regulation of diverse cell responses. Am J Physiol Lung Cell Mol Physiol 279: L429-L438, 2000.
14. Do SH, Kamatchi GL, Washington JM, and Zuo Z. Effects of volatile anesthetics on glutamate transporter, excitatory amino acid transporter type 3. Anesthesiology 96: 1492-1497, 2002.
15. Durieux ME. An IBM-compatible software system for electrophysiologic receptor studies in Xenopus oocytes. Comput Methods Programs Biomed 41: 101-105, 1993.
16. Fairman WA, Sonders MS, Murdoch GH, and Amara SG. Arachidonic acid elicits a substrate-gated proton current associated with the glutamate transporter EAAT4. Nat Neurosci 1: 105-113, 1998.
17. Fairman WA, Vandenberg RJ, Arriza JL, Kavanaugh MP, and Amara SG. An excitatory amino-acid transporter with properties of a ligand-gated chloride channel. Nature 375: 599-603, 1995.
18. Fang H, Huang Y, and Zuo Z. The different responses of rat glutamate transporter type 2 and its mutant (tyrosine 403 to histidine) activity to volatile anesthetics and activation of protein kinase C. Brain Res 953: 255-264, 2002.
19. Furuta A, Martin LJ, Lin CL, Dykes-Hoberg M, and Rothstein JD. Cellular and synaptic localization of the neuronal glutamate transporters excitatory amino acid transporter 3 and 4. Neuroscience 81: 1031-1042, 1997.
20. Goekjian PG and Jirousek MR. Protein kinase C in the treatment of disease: signal transduction pathways, inhibitors, and agents in development. Curr Med Chem 6: 877-903, 1999.
21. Gonzalez MI, Kazanietz MG, and Robinson MB. Regulation of the neuronal glutamate transporter excitatory amino acid carrier-1 (EAAC1) by different protein kinase C subtypes. Mol Pharmacol 62: 901-910, 2002.
22. Grunewald M and Kanner BI. The accessibility of a novel reentrant loop of the glutamate transporter GLT-1 is restricted by its substrate. J Biol Chem 275: 9684-9689, 2000.
23. Hoffman K and Stoffel W. TMbase: a database of membrane spanning protein segments. Biol Chem Hoppe Seyler 374: 166, 1993.
24. Hu WH, Walters WM, Xia XM, Karmally SA, and Bethea JR. Neuronal glutamate transporter EAAT4 is expressed in astrocytes. Glia 44: 13-25, 2003.
25. Huang Y and Zuo Z. Isoflurane induces a protein kinase Cα-dependent increase in cell surface protein level and activity of glutamate transporter type 3. Mol Pharmacol 67: 1522-1533, 2005.
26. Kanai Y, Stelzner M, Nussberger S, Khawaja S, Hebert SC, Smith CP, and Hediger MA. The neuronal and epithelial human high affinity glutamate transporter: insights into structure and mechanism of transport. J Biol Chem 269: 20599-20606, 1994.
27. Klockner U, Storck T, Conradt M, and Stoffel W. Electrogenic L-glutamate uptake in Xenopus laevis oocytes expressing a cloned rat brain L-glutamate/L-aspartate transporter (GLAST-1). J Biol Chem 268: 14594-14596, 1993.
28. Lehre KP, Levy LM, Ottersen OP, Storm-Mathisen J, and Danbolt NC. Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations. J Neurosci 15: 1835-1853, 1995.
29. Lin CLG, Tzingounis AV, Jin L, Furuta A, Kavanaugh MP, and Rothstein JD. Molecular cloning and expression of the rat EAAT4 glutamate transporter subtype. Mol Brain Res 63: 174-179, 1998.
30. Matthews G and Diamond JS. Neuronal glutamate uptake contributes to GABA synthesis and inhibitory synaptic strength. J Neurosci 23: 2040-2048, 2003.
31. Merritt JE, Sullivan JA, Tse J, Wilkinson SE, and Nixon JS. Different sensitivities of neutrophil responses to a selective protein kinase C inhibitor, Ro 31-8425; redundancy in signal transduction. Cell Signal 9: 53-57, 1997.
32. Nagao S, Kwak S, and Kanazawa I. EAAT4, a glutamate transporter with properties of a chloride channel, is predominantly localized in Purkinje cell dendrites, and forms parasagittal compartments in rat cerebellum. Neuroscience 78: 929-933, 1997.
33. Nishizuka Y. Protein kinase C and lipid signaling for sustained cellular responses. FASEB J 9: 484-496, 1995.
34. 2+-ATPase activity in rat liver nuclei. J Cell Biochem 55: 168-172, 1994.
35. Poulsen MV and Vandenberg RJ. Niflumic acid modules uncoupled substrate-gated conductances in the human glutamate transporter EAAT4. J Physiol 534: 159-167, 2001.
36. Rothstein JD, Martin L, Levey AI, Dykes-Hoberg M, Jin L, Wu D, Nash N, and Kuncl RW. Localization of neuronal and glial glutamate transporters. Neuron 13: 713-725, 1994.
37. Seal RP, Leighton BH, and Amara SG. A model for the topology of excitatory amino acid transporters determined by the extracellular accessibility of substituted cysteines. Neuron 25: 695-706, 2000.
38. Sepkuty JP, Cohen AS, Eccles C, Rafiq A, Behar K, Ganel R, Coulter DA, and Rothstein JD. A neuronal glutamate transporter contributes to neurotransmitter GABA synthesis and epilepsy. J Neurosci 22: 6372-6379, 2002.
39. Takahashi M, Kovalchuk Y, and Attwell D. Presynaptic and postsynaptic determinates of EPSC waveform at cerebellular climbing fiber and parallel fiber to Purkinje cell synapses. J Neurosci 15: 5693-5702, 1995.
40. +-dependent glutamate transporter: pharmacological characterization and lack of regulation by protein kinase C. J Pharmacol Exp Ther 289: 1600-1610, 1999.
41. Tzingounis AV, Lin CL, Rothstein JD, and Kavanaugh MP. Arachidonic acid activates a proton current in the rat glutamate transporter EAAT4. J Biol Chem 273: 17315-17317, 1998.
42. Wadiche JI, Amara SG, and Kavanaugh MP. Ion fluxes associated with excitatory amino acid transport. Neuron 15: 721-728, 1995.
43. Ward MM, Jobling AI, Puthussery T, Foster LE, and Fletcher EL. Localization and expression of the glutamate transporter, excitatory amino acid transporter 4, within astrocytes of the rat retina. Cell Tissue Res 315: 305-310, 2004.
44. Way KJ, Chou E, and King GL. Identification of PKC-isoform-specific biological actions using pharmacological approaches. Trends Pharmacol Sci 21: 181-187, 2000.
45. White JR, Huang CK, Hill JM Jr, Naccache PH, Becker EL, and Sha'afi RI. Effect of phorbol 12-myristate 13-acetate and its analogue 4 alpha-phorbol 12,13-didecanoate on protein phosphorylation and lysosomal enzyme release in rabbit neutrophils. J Biol Chem 259: 8605-8611, 1984.
46. Wilkinson SE, Parker PJ, and Nixon JS. Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C. Biochem J 294: 335-337, 1993.
47. Yamada K, Watanabe M, Shibata T, Tanaka K, Wade K, and Inoue Y. EAAT4 is a post-synaptic glutamate transporter at Purkinje cell synapses. Neuroreport 7: 2013-2017, 1996.
48. Zerangue N, Arriza JL, Amara SG, and Kavanaugh MP. Differential modulation of human glutamate transporter subtypes by arachidonic acid. J Biol Chem 270: 6433-6435, 1995.