Real-time detection of epidermal growth factor receptor expression in fresh oral cavity biopsies using a molecular-specific contrast agent

International Journal of Cancer

Volumn 118, Issue 12, 2006, Pages 3062-3071

  Hsu, Elizabeth R ^a   Gillenwater, Ann M ^b   Hasan, M Qasim ^b   Williams, Michelle D ^b   El Naggar, Adel K ^b   Richards Kortum, Rebecca R ^c  

^a The University of Texas at Austin   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c Rice University   (United States)

Author keywords

Epidermal growth factor receptor; Fluorescent contrast agent; Molecular specific contrast agent

Indexed keywords

CONTRAST MEDIUM; EPIDERMAL GROWTH FACTOR RECEPTOR; FLUORESCENT DYE; MONOCLONAL ANTIBODY; RED FLUORESCENT PROTEIN;

ARTICLE; BIOPSY; CANCER INVASION; CANCER PATIENT; CANCER SURVIVAL; CONFOCAL MICROSCOPY; EARLY DIAGNOSIS; HEAD AND NECK CANCER; HIGH RISK BEHAVIOR; HUMAN; HUMAN TISSUE; MOUTH CAVITY; MOUTH MUCOSA; ORGAN CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; SURVIVAL RATE; TISSUE SPECIFICITY;

BIOPSY; CONTRAST MEDIA; EARLY DIAGNOSIS; FLUORESCENT ANTIBODY TECHNIQUE; FLUORESCENT DYES; HUMANS; MICROSCOPY, FLUORESCENCE; MOUTH MUCOSA; MOUTH NEOPLASMS; PRECANCEROUS CONDITIONS; RECEPTOR, EPIDERMAL GROWTH FACTOR; TEMPERATURE;

EID: 33646417361     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.21720     Document Type: Article

References (51)

1. American Cancer Society. Cancer Reference Information, 2003.
2. Yeole BB, Ramanakumar AV, Sankaranarayanan R. Survival from Oral Cancer in Mumbai (Bombay), India. Cancer Causes Control 2003; 14:945-52.
3. Mashberg A. Diagnosis of Early Oral and Oralpharyngeal Squamous Carcinoma: Obstacles and Their Amelioration. Oral Oncol 2000;36:253-55.
4. Srinivas PR, Kramer BS, Srivastava S. Trends in Biomarker Research for Cancer Detection. Lancet Oncol 2001;2:698-704.
5. Hsu ER, Anslyn EV, Dharmawardhane S, Alizadeh-Naderi R, Aaron JS, Sokolov KV, El-Naggar AK, Gillenwater AM, Richards-Kortum RR. A far-red fluorescent contrast agent to image epidermal growth factor receptor expression. Photochem Photobiol 2004;79:272-79.
6. Gillenwater A, Jacob R, Ganeshappa R, Kemp B, El-Naggar AK, Palmer JL, Clayman G, Mitchell MF, Richards-Kortum R. Noninvasive diagnosis of oral neoplasia based on fluorescence spectroscopy and native tissue autofluorescence. Arch Otolaryngol Head Neck Surg 1998;124:1251-8.
7. Heintzelman DL, Utzinger U, Fuchs H, Zuluaga A, Gossage K, Gillenwater AM, Jacob R, Kemp B, Richards-Kortum RR. Optimal excitation wavelengths for in vivo detection of oral neoplasia using fluorescence spectroscopy. Photochem Photobiol 2000;72: 103-13.
8. Ramanujam N. Fluorescence spectroscopy of neoplastic and non-neoplastic tissues. Neoplasia 2000;2:89-117.
9. Wagnières GA, Star WM, Wilson BC. In vivo fluorescence spectroscopy and imaging for oncological applications. Photochem Photobiol 1998;68:603-32.
10. Müller MG, Valdez TA, Georgakoudi I, Backman V, Fuentes C, Kabani S, Laver N, Wang Z, Boone CW, Dasari RR, Shapshay SM, Feld MS. Spectroscopic detection and evaluation of morphologic and biochemical changes in early human oral carcinoma. Cancer 2003; 97:1681-92.
11. Schantz SP, Kolli V, Savage HE, Yu G, Shah JP, Harris DE, Katz A, Alfano RR, Huvos AG. In vivo native cellular fluorescence and histological characteristics of head and neck cancers. Clin Cancer Res 1998;4:1177-4.
12. Betz CS, Mehlmann M, Rick K, Stepp H, Grevers G, Baumgartner R, Leunig A. Autofluorescence imaging and spectroscopy of normal and malignant mucosa in patients with head and neck cancer. Lasers Surg Med 1999;25:323-34.
13. Svistun E, Alizadeh-Naderi R, El-Naggar A, Jacob R, Gillenwater A, Richards-Kortum R. Vision enhancement system for detection of oral cavity neoplasia based on autofluorescence. Head Neck 2004;26:205-15.
14. Benavides JM, Chang S, Park SY, Richards-Kortum R, Mackinnon N, MacAulay C, Milbourne A, Malpica A, Follen M. Multispectral digital colposcopy for in vivo detection of cervical cancer. Optics Express 2003;11:1223-36.
15. Ferris DG, Lawhead RA, Dickman ED, Holtzapple N, Miller JA, Grogan S, Bambot S, Agrawal A, Faupel ML. Multimodal hyperspectral imaging for the noninvasive diagnosis of cervical neoplasia. J Low Genit Tract Dis 2001;5:65-72.
16. Park S-Y, Collier T, Aaron J, Markey MK, Richards-Kortum R, Sokolov K, Mackinnon N, MacAulay C, Coghlan L, Milbourne A, Follen M. Multispectral digital microscopy for in vivo monitoring of oral neoplasia in the hamster cheek pouch model of carcinogenesis. Optics Express 2005;13:749-61.
17. Anikijenko P, Vo LT, Murr ER, Carrasco J, McLaren WJ, Chen Q, Thomas SG, Delaney PM, King RG. In vivo detection of small subsurface melanomas in athymic mice using noninvasive fiber optic confocal imaging. J Invest Dermatol 2001;117:1442-4.
18. Clark AL, Gillenwater AM, Collier TG, Alizadeh-Naderi R, El-Naggar AK, Richards-Kortum RR. Confocal microscopy for real-time detection of oral cavity neoplasia. Clin Cancer Res 2003;9:4714-21.
19. Collier T, Lacy A, Richards-Kortum R, Malpica A, Folien M. Near real-time confocal microscopy of amelanotic tissue: detection of dysplasia in ex vivo cervical tissue. Acad Radiol 2002;9:504-12.
20. Gmitro AF, Aziz D. Confocal microscopy through a fiber-optic imaging bundle. Opt Lett 1993;18:565-67.
21. Jüskaitis R, Wilson T. Imaging in reciprocal fibre-optic based confocal scanning microscopes. Optics Communications 1992;92:315-25.
22. Sung KB, Liang C, Descour M, Collier T, Follen M, Malpica A, Richards-Kortum R. Near real time in vivo fibre optic confocal microscopy: sub-cellular structure resolved. J Microsc 2002;207:137-45.
23. Sung KB, Liang C, Descour M, Follen M, Richards-Kortum R. Fiber optic confocal microscope with miniature objective for in-vivo imaging. IEEE Trans Biomed Eng 2002;49:1168-72.
24. White WM, Rajadhyaksha M, Gonzalez S, Fabian RL, Anderson RR. Noninvasive imaging of human oral mucosa in vivo by confocal reflectance microscopy. Laryngoscope 1999;109:1709-17.
25. Swindle LD, Thomas SG, Freeman M, Delaney PM. View of normal human skin in vivo as observed using fluorescent fiber-optic confocal microscopic imaging. J Invest Dermatol 2003;121:706-12.
26. Carpenter G. Receptors for epidermal growth factor and other polypeptide mitogens. Annu Rev Biochem 1987;56:881-914.
27. Shin DM, Ro JY, Hong WK, Hittelman WN. Dysregulation of epidermal growth factor receptor expression in premalignant lesions during head and neck tumorigenesis. Cancer Res 1994;54:3153-9.
28. Ishitoya J, Toriyama M, Oguchi N, Kitamura K, Ohshima M, Asano K, Yamamoto T. Gene amplification and overexpression of egf receptor in squamous cell carcinomas of the head and neck. Br J Cancer 1989;59:559-62.
29. Scambia G, Panici PB, Battaglia F, Ferrandina G, Almadori G, Paludetti G, Maurizi M, Mancuso S. Receptors for epidermal growth factor and steroid hormones in primary laryngeal tumors. Cancer 1991; 67:1347-51.
30. Kawamoto T, Takahashi K, Nishi M, Kimura T, Matsumura T, Taniguchi S. Quantitative assay of epidermal growth factor receptor in human squamous cell carinomas of the oral region by an avidin-biotin method. Jpn J Cancer Res 1991;82:403-10.
31. Santini J, Formento J-L, Francoual M, Milano G, Schneider M, Dassonville O, Demard F. Characterization, quantification, and potential clinical value of the epidermal growth factor receptor in head and neck squamous cell carcinomas. Head Neck 1991;13:132-9.
32. Christensen ME, Engbaek F, Therkildsen MH, Bretlau P, Nexø E. A sensitive enzyme-linked immunosorbent assay used for quantitation of epidermal growth factor receptor protein in head and neck carcinomas: evaluation, interpretations and limitations. BrJ Cancer 1995;72: 1487-93.
33. Ang KK, Berkey BA, Tu X, Zhang H-Z, Katz R, Hammond EH, Fu KK, Milas L. Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced heand and neck carcinoma. Cancer Res 2002;62:7350-6.
34. Soukos NS, Hamblin MR, Keel S, Fabian RL, Deutsch TF, Hasan T. Epidermal growth factor receptor-targeted immunophotodiagnosis and photoimmunotherapy of oral precancer in vivo. Cancer Res 2001; 61:4490-6.
35. Ke S, Wen X, Gurfinkel M, Charnsangavej C, Wallace S, Sevick-Muraca EM, Li C. Near-infrared optical imaging of epidermal growth factor receptor in breat cancer xenografts. Cancer Res 2003;63:7870-5.
36. Winning TA. Townsend GC. Oral mucosal embryology and histology. Clin Dermatol 2000;18:499-511.
37. Bergler W, Bier H, Ganzer U. The expression of epidermal growth factor receptors in the oral mucosa of patients with oral cancer. Arch Otorhinolaryngol 1989;246:121-5.
38. Boiko IV, Mitchell MF, Hu W, Pandey DK, Mathevet P, Malpica A, Hittelman WN. Epidermal growth factor receptor expression in cervical intraepithelial neoplasia and its modulation during an α-difluoromethylornithine chemoprevention trial. Clin Cancer Res 1998;4: 1383-91.
39. Christensen ME, Therkildsen MH, Hansen BL, Hansen GN, Bretlau P. Immunohistochemcial detection of epidermal growth factor receptor in laryngeal squamous cell carcinomas. Acta Oto-Laryngologica (Stockholm). 1992;112:734-38.
40. Putti TC, To KF, Hsu HC, Chan ATC, Lai GM, Tse G, Lee YS, Whang-Peng J, Millward M, Lin L, Lin X, Lee CS. Expression of epidermal growth factor receptor in head and neck cancers correlates with clinical progression: a multicentre immunohistochemical study in the asia-pacific region. Histopathology 2002;41:144-51.
41. Shirasuna K, Hayashido Y, Sugiyama M, Yoshioka H, Matsuya T. Immunohistochemical localization of epidermal growth factor (EGF) and EGF receptor in human oral mucosa and its malignancy. Virchows Archiv A Pathol. Anat Histopathol 1991;418:349-53.
42. Whitcomb SS, Eversole LR, Lindemann RA. Immunohistochemical mapping of epidermal growth-factor receptors in normal human oral soft tissue. Arch Oral Biol 1993;38:823-6.
43. Prime SS, Game SM, Mathhews IB, Stone A, Donnelly MI, Yeudall WA, Patel V, Sposto R, Silverthorne A, Scully C. Epidermal growth factor and transforming growth factor α characteristics of human oral carcinoma cell lines. Br J Cancer 1994;69:8-15.
44. Nieman L, Myakov A, Aaron J, Sokolov K. Optical sectioning using a fiber probe with an angled illumination-collection geometry: evaluation in engineering tissue phantoms. Applied Optics 2004;43:1308-19.
45. Skala MC, Palmer GM, Zhu C, Liu Q, Vrostsos KM, Marsek-Stone CL, Gendron-Fitzpatrick A, Ramanujam N. Investigation of fiber-optics probe designs for optical spectroscopic diagnosis of epithelial pre-cancers. Lasers Surg Med 2004;34:25-38.
46. Boerman Oc, Schaijk FGv, Oyen WJG, Corstens FHM. Pretargeted radioimmunotherapy of cancer: progress step by step. J Nucl Med 2003;44:400-11.
47. Moro M, Pelagi M, Fulci G, Paganelli G, Dellabona P, Casorati G, Siccardi AG, Corti A. Tumor cell targeting wth antibody-avidin complexes and biotinylated tumor necrosis Factor a. Cancer Res 1997; 57:1922-8.
48. Reali E, Greiner JW, Corti A, Gould HJ, Bottazzoli F, Paganelli G, Schlom J, Siccardi AG. IgEs targeted on tumor cells: therapeutic activity and potential in the design of tumor vaccines. Cancer Res 2001;61:5517-22.
49. Yu Z-W, Quinn PJ. The modulation of membrane structure and stability by dimethyl sulphoxide. Mol Membr Biol 1998;15:59-68.
50. Schechter B, Arnon R, Wilchek M, Schlessinger J, Hurwitz E, Aboud-Pirak E, SeIa M. Indirect immunotargeting of cis-pt to human epidermoid carcinoma KB using the Avidin-Biotin system. Int J Cancer 1991;48:167-72.
51. Guttinger M, Guidi F, Chinol M, Reali E, Veglia F, Viale G, Paganelli G, Corti A, Siccardi AG. Adoptive immunotherapy by Avidin-driven Cytotoxic T Lymphocyte Tumor Bridging. Cancer Res 2000;60: 4211-15.