Abnormalities of the hippocampus are similar in deoxycorticosterone acetate-salt hypertensive rats and spontaneously hypertensive rats

Journal of Neuroendocrinology

Volumn 18, Issue 6, 2006, Pages 466-474

  Pietranera, L ^a,b   Saravia, F ^a,b   Gonzalez Deniselle, M C ^a,b   Roig, P ^a   Lima, A ^a   De Nicola, Alejandro F ^a,b,c  

^a INST DE BIOL Y MED EXPERIMENTAL   (Argentina)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^c Argentina   (Argentina)

Author keywords

Astrocytes; Dentate gyrus; DOCA salt hypertension; Hippocampus; Mineralocorticoids; Neurogenesis; SHR

Indexed keywords

APOLIPOPROTEIN E; BIOLOGICAL MARKER; BROXURIDINE; DEOXYCORTICOSTERONE ACETATE; GLIAL FIBRILLARY ACIDIC PROTEIN; MINERALOCORTICOID RECEPTOR; SODIUM CHLORIDE;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN DAMAGE; CELL COUNT; CELL DENSITY; CELL PROLIFERATION; CONTROLLED STUDY; DENTATE GYRUS; GLIOSIS; HIPPOCAMPUS; HORMONE BLOOD LEVEL; HYPERTENSION; HYPOTHALAMUS HYPOPHYSIS SYSTEM; IMMUNOCYTOCHEMISTRY; MALE; MORPHOMETRICS; NERVE CELL; NERVE CELL LESION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; SENSITIVITY ANALYSIS; SPONTANEOUSLY HYPERTENSIVE RAT; STRAIN DIFFERENCE;

ANIMALS; APOLIPOPROTEINS E; ASTROCYTES; CELL DIVISION; DENTATE GYRUS; DESOXYCORTICOSTERONE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOSIS; HYPERTENSION; MALE; NEURONS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RATS, SPRAGUE-DAWLEY; SODIUM CHLORIDE; SPECIES SPECIFICITY;

EID: 33646358943     PISSN: 09538194     EISSN: 13652826     Source Type: Journal    
DOI: 10.1111/j.1365-2826.2006.01436.x     Document Type: Article

References (64)

1. Macleod MR, Johansson I-M, Soderstrom I, Lai M, Gido G, Wieloch T, Seckl JR, Olsson T. Mineralocorticoid receptor expression and increased survival following neuronal injury. Eu J Neurosci 2003; 17: 1549-1555.
2. De Kloet ER, Joels M, Holsboer F. Stress and the brain: From adaptation to disease. Nature Neurosci 2005; 6: 463-475.
3. McEwen BS. Protection and damage from acute and chronic stress: allostasis and allostatic overload and relevance to the pathophysiology of psychiatric disorders. Ann NY Acad Sci 2004; 1032: 1-7.
4. Krugers HS, Maslam S, Korf J, Joels M. The corticosteroid synthesis inhibitor metyrapone prevents hypoxia/ischemia-induced loss of synaptic function in the rat hippocampus. Stroke 2000; 31: 1162 -1172.
5. Gomez Sanchez EP. Central hypertensive effects of aldosterone. Front Neuroendocrinol 1997; 18: 440-463.
6. De Wandener HE. The hypothalamus and hypertension. Physiol Rev 2001; 81: 1599-1658.
7. Pietranera L, Saravia F, McEwen BS, Lucas LL, Johnson AK, De Nicola AF. Changes in Fos expression in various brain regions during deoxycorticosterone acetate treatment: Relation to salt appetite, vasopressin mRNA and the mineralocorticoid receptor. Neuroendocrinology 2001; 74: 396-406.
8. Johnson AK, de Olmos J, Pastuskovas CV, Zardetto-Smith AM, Vivas L. The extended amygdala and salt appetite. Ann New York Acad Sci 1999; 877: 258-280.
9. Brody MJ, Johnson AK. Role of the anteroventral third ventricular region on fluid and electrolyte balance, arterial pressure regulation and hypertension. Front Neuroendocrinol 1980; 6: 249-292.
10. Sakai RR, McEwen BS, Fluharty SJ, Na LY. The amygdala: Site of genomic and nongenomic arousal of aldosterone-induced salt intake. Kidney Int 2000; 57: 1337-1345.
11. McEwen BS, Lambdin LT, Rainbow TC, De Nicola AF. Aldosterone effects on salt appetite in adrenalectomised rats. Neuroendocrinology 1986; 43: 38-43.
12. Grillo C, Saravia F, Ferrini M, Piroli G, Roig P, Garcia S, de Kloet ER, De Nicola AF. Increased expression of magnocellular vasopressin mRNA in rats with DOCA-induced salt appetite. Neuroendocrinology 1998; 68: 105 -115.
13. Saravia F, Grillo C, Ferrini M, Roig P, Lima A, de Kloet ER, De Nicola AF. Changes of hypothalamic and plasma vasopressin in rats with deoxycorticosterone-acetate induced salt appetite. J Steroid Biochem Mol Biol 1999; 70: 47-57.
14. Saavedra JM. Brain angiotensin II: New developments, unanswered questions and therapeutic opportunities. Cell Mol Neurobiol 2005; 25: 485 -512.
15. Lucas LR, Pompei P, McEwen BS. Salt appetite in salt-replete rats: involvement of mesolimbic structures in deoxycorticosterone-induced salt craving behavior. Neuroendocrinology 2000; 71: 386-395.
16. Van den Berg DTWM, de Kloet ER, Van Dijken HH, de Jong W. Differential central effects of mineralocorticoid and glucocorticoid agonists and antagonists on blood pressure. Endocrinology 1988; 126: 118-190.
17. Bealer SL. Hypothalamic knife cuts attenuate maintenance of deoxycorticosteroneacetate salt-induced hipertensión. Brain Res 1984; 309: 192-195.
18. Van den Berg DTWM, de Kloet ER, de Jong W. Central effects of mineralocorticoid antagonist RU-28318 on blood pressure of DOCA-salt hypertensive rats. Am J Physiol (Endocrinol Metab) 1994; 30: E927-E933.
19. Vallee SM, Grillo C, Gonzalez S, Cosen-Binker L, de Kloet ER, McEwen BS, De Nicola AF. Further studies in DOCA-treated rats: Brain content of mineralocorticoid and glucocorticoid receptors and effect of steroid antagonists on salt intake. Neuroendocrinology 1995; 61: 117 -124.
20. McEwen BS, Weiss JM, Schwartz LS. Selective retention of corticosterone by limbic structures in rat brain. Nature 1968; 220: 911-912.
21. Van Eekelen JAM, Juang W, De Kloet ER, Bohn MC. Distribution of the mineralocorticoid and the glucocorticoid receptor mRNAs in the rat hippocampus. J Neurosci Res 1988; 21: 88-94.
22. Ahima R, Krozowski Z, Harlan R. Type I corticosteroid receptor-like immunoreactivity in the rat CNS: Distribution and regulation by corticosteroids. J Comp Neurol 1991; 313: 522-538.
23. Grillo CA, Vallee S, McEwen BS, De Nicola AF. Properties and distribution of binding sites for the mineralocorticoid receptor antagonist (3 H)-ZK 91587 in brain. J Steroid Biochem Mol Biol 1990; 35: 11-15.
24. Seckl JR. 11beta-Hydroxysteroid dehydrogenase in the brain: A novel regulator of glucocorticoid action? Front Neuroendocrinol 1997; 18: 49-99.
25. Sabbatini M, Strocchi P, Vitaioli L, Amenta P. The hippocampus in spontaneously hypertensive rats: A quantitative microanatomical study. Neuroscience 2000; 100: 251-258.
26. Sabbatini M, Catalani A, Consoli C, Marletta N, Tomassoni D, Avola R. The hippocampus in spontaneously hypertensive rats: An animal model of dementia. Mech Ageng Dev 2002; 123: 547-559.
27. Tomassoni D, Avola R, Di Tullio A, Sabbatini M, Vitaioli L, Amenta F. Increased expression of glial fibrillary acidic protein in the brain of spontaneously hypertensive rats. Clin Exp Hyp 2004; 26: 335-350.
28. Ueno M, Sakamoto H, Tomimoto H, Akiguchi I, Onodera M, Huang C-L, Kamenishi K. Blood-brain barrier is impaired in the hippocampus of young adult spontaneously hypertensive rats. Acta Neuropathol 2002; 107: 532-538
29. Perfilieva E, Risedal A, Nyberg A, Johansson BB, Wriksson PS. Gender and strain influence on neurogenesis in dentate gyrus of young rats. J Cer Blood Flow Metab 2001; 21: 211-217.
30. Hashimoto K, Makino S, Hirasawa R, Takao T, Sugawara M, Murakami K, Ono K, Ota Z. Abnormalities in the hypothalamic-pituitary-adrenal axis in spontaneously hypertensive rats during development of hypertension. Endocrinology 1989; 125: 1161-1167.
31. Gomez F, Lahmame A, De Kloet ER, Armario A. Hypothalamic-pituitary-adrenal response to chronic stress in five inbred rat strains: Differential responses are mainly located at the adrenocortical level. Neuroendocrinology 1986; 63: 327-337.
32. Rahmouni K, Barthelmebs M, Grima M, Imbs JL, De Jong W. Involvement of brain mineralocorticoid receptor in salt-enhanced hypertension in spontaneously hypertensive rats. Hypertension 2001; 38: 902-906.
33. Kenyon CJ, De Conti GA, Cupolo NA, Morris DJ. The role of aldosterone in the development of hypertension in spontaneously hypertensive rats. Endocrinology 1981; 109: 1841-1845
34. Mirshahi M, Nicolas C, Agarwal MK. Enhanced activation of the mineralocorticoid receptor in genetically hypertensive rats. Biochem Biophys Res Commun 1998; 244: 120-125.
35. Sutanto W, Oitzl MS, Rots NY, Schobitz B, Van den Berg DT, Van Dijken HH, Mos J, Cools AR, Tilders FJ, Koolhaas JM. Corticosteroid receptor plasticity in the central nervous system of various rat models. Endocr Regul 1992; 26: 111-118.
36. Konishi A, Tazawa C, Miki Y, Darnel AD, Suzuki T, Ohta Y, Suzuki T, Tabayashi K, Sasano H. The possible roles of mineralocorticoid receptor and 11 β-hydroxysteroid dehydrogenase type 2 in cardiac fibrosis in the spontaneously hypertensive rat. J Steroid Biochem Mol Biol 2003; 85: 439-442.
37. Pietranera L, Saravia F, Roig P, Lima A, De Nicola AF. Mineralocorticoid treatment upregulates the hypothalamic vasopressinergic system of spontaneously hypertensive rats. Neuroendocrinology 2004; 80: 100-110.
38. McMahon SS, McDermott KW. Proliferation and migration of glial precursor cells in the developing rat spinal cord. J Neurocytol 2001; 30: 821-828.
39. Saravia F, Revsin Y, Lux-Lantos V, Beauquis J, Homo-Delarche F, De Nicola AF. Oestradiol restores cell proliferation in dentate gryus and subventricular zone of streptozotocin-diabetic rats. J Neuroendocrinol 2004; 16: 704-710.
40. Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates. Sydney: Academic Press, 1982.
41. Coggeshall R, Lekan H. Methods for determining numbers of cells and synapses: A case for more uniform standards of review. J Comp Neurol 1996; 364: 6-15.
42. West M. Regionally specific loss of neurons in the aging human hippocampus. Neurobiol Aging 1993; 14: 287-293.
43. Revsin Y, Saravia F, Roig P, Lima A, de Kloet ER, Homo-Delarche F, De Nicola AF. Neuronal and astroglial alterations in the hippocampus of a mouse model for type 1 diabetes. Brain Res 2005; 1038: 22-31.
44. Howart C, Reed M. Unbiased Stereology. Three-Dimensional Measurement in Microscopy. Oxford: Bios Scientific Publishers Ltd, 1998: 45.
45. Sapolsky R, Krey L, McEwen BS. The neuroendocrinology of stress and aging: The glucocorticoid cascade hypothesis. Endocr Rev 1986; 7: 284-301.
46. Landfield PW, Waymire JC, Lynch G. Hippocampal aging and adrenocorticoids: Quantitative correlations. Science 1978; 202: 1098-1102.
47. Magariños AM, McEwen BS. Experimental diabetes in rats causes hippocampal dendritic and synaptic reorganization and increased glucocorticoid reactivity to stress. Proc Natl Acad Sci USA 2000; 97: 11056-11061.
48. Delano FA, Schmid-Schonbein GW. Enhancement of glucocorticoid and mineralocorticoid receptor density in the microcirculation of the spontaneously hypertensive rat. Mirocirculation 2004; 11: 69-78.
49. Dempsey RJ, Sailor KA, Bowen KK, Tureyen K, Vermuganti R. Stroke-induced cell proliferation in adult hypertrensive rat brain: Effect of exogenous IGF-1 and GDNF. J Neurochem 2003; 87: 586-597.
50. Komanicky P, Reiss DL, Dale SL, Melby JC. Role of adrenal steroidogenesis in etiology of hypertension in the spontaneously hypertensive rat. Endocrinology 1982; 111: 219-224
51. Wong EYH, Herbert J. Roles of mineralocorticoid and glucocorticoid receptors in the regulation of progenitor proliferation in the adult hippocampus. Eur J Neurosci 2005; 22: 785-792.
52. Rocha R, Chander PN, Khanna K, Zuckerman A, Stier CT. Mineralocorticoid blockade reduces vascular injury in stroke-prone hypertensive rats. Hypertension 1998; 31: 451-458.
53. Lambert KG, Gerecke KM, Quadros PS, Doudera E, Jasnow AJ, Kinsley CH. Activity-stress increases density of GFAP-immunoreactive astrocytes in the rat hippocampus. Stress 2000; 4: 275-284.
54. Boschert U, Merlo-Pich E, Higgins G, Roses AD, Catsicas S. Apolipoprotein E expression by neurons surviving excitotoxic stress. Neurobiol Dis 1999; 6: 508 -514.
55. Weeber EJ, Beffert U, Jones C, Christian JM, Forster E, Sweat JD, Herz J. Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning. J Biol Chem 2002; 277: 39944-39952.
56. Muller HW, Matthiese HP, Schmalenbach C, Schroeder WO. Glial support of CNS neuronal survival, neurite growth and regeneration. Rest Neurol Neurosci 1991; 2: 229-232.
57. Norenberg MD. Astrocyte responses to CNS injury. J Neuropathol Exp Neurol 1994; 53: 213-220.
58. Hastings NB, Gould E. Rapid extension of axons into the CA3 region of adult-generated granule cells. J Comp Neurol 1999; 413: 146-154.
59. Seaberg RM, van der Kooy D. Stem and progenitor cells: The premature desertion of rigorous definitions. TINS 2003; 26: 125-131
60. Cameron HA, Gould E. Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus. Neurosci 1994; 61: 203-209.
61. Garcia A, Steiner B, Kronenberg G, Bick-Sander A, Kempermann G. Age dependent expression of glucocorticoid-and mineralocorticoid receptors on neural precursor cell populations in the adult murine hippocampus. Aging Cell 2004; 3: 363-371.
62. Mody I, Otis TS, Bragin A, Hsu M, Bizsaki G. GABAergic inhibition of granule cells and hilar al synchrony following ischemia-induced hilar neuronal loss. Neuroscience 1995; 69: 139-150.
63. Azcoitia I, Sierra A, Garcia-Segura LM. Estradiol prevents kainic acid-induced neuronal loss in the rat dentate gyrus. Neuroreport 1998; 9: 3075-3079.
64. Behl C. Sex hormones, neuroprotection and cognition. Prog Brain Res 2002; 138: 135-142.