Generalist genes: implications for the cognitive sciences

Trends in Cognitive Sciences

Volumn 10, Issue 5, 2006, Pages 198-203

  Kovas, Yulia ^a   Plomin, Robert ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; GENES; MATHEMATICAL TECHNIQUES; NEUROLOGY;

COGNITIVE SCIENCES; GENERALIST GENES; GENETIC RESEARCH; NEUROSCIENCE; PLEIOTROPY; POLYGENICITY;

COGNITIVE SYSTEMS;

BRAIN DERIVED NEUROTROPHIC FACTOR; CATECHOL METHYLTRANSFERASE; DNA; MESSENGER RNA; RNA; TRANSCRIPTOME;

ANTEROGRADE AMNESIA; ARTICLE; BRAIN; BRAIN REGION; COGNITION; DNA MICROARRAY; FRONTAL LOBE; GENE EXPRESSION; GENE FUNCTION; GENE LOCATION; GENE MAPPING; GENE STRUCTURE; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GENETICS; GENOME; HUMAN; MOUSE STRAIN; NEUROIMAGING; NEUROLOGIC DISEASE; NEUROSCIENCE; NONHUMAN; PARIETAL LOBE; PLEIOTROPY; QUANTITATIVE TRAIT LOCUS; TEMPORAL LOBE;

ANIMALS; BRAIN; CATECHOL O-METHYLTRANSFERASE; COGNITION; COGNITIVE SCIENCE; DNA; GENE EXPRESSION; GENETICS; RNA;

EID: 33646352936     PISSN: 13646613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tics.2006.03.001     Document Type: Article

References (29)

1. Plomin R., and Kovas Y. Generalist genes and learning disabilities. Psychol. Bull. 131 (2005) 592-617
2. Petrill S.A. The case for general intelligence: a behavioral genetic perspective. In: Sternberg R.J., and Grigorenko E.L. (Eds). The General Factor of Intelligence: How General Is It? (2002), Erlbaum 281-298
3. Plomin R., and Spinath F.M. Genetics and general cognitive ability (g). Trends Cogn. Sci. 6 (2002) 169-176
4. Deary I.J. Human intelligence differences: towards a combined experimental-differential approach. Trends Cogn. Sci. 5 (2001) 164-170
5. Dudley, A.M. et al. (2005) A global view of pleiotropy and phenotypically derived gene function in yeast. Mol. Syst. Biol. doi: 10.1038/msb4100004
6. Grant S.G.N., et al. Synapse proteomics of nultiprotein complexes: an route from genes to nervous sytem diseases. Hum. Mol. Genet. 14 (2005) R225-R234
7. Greenberg S.A. DNA microarray gene expression analysis technology and its application to neurological disorders. Neurology 57 (2001) 755-761
8. Mattick J.S. The functional genomics of noncoding RNA. Science 309 (2005) 1527-1528
9. Plomin, R. et al. The quest for quantitative trait loci associated with intelligence. Intelligence (in press)
10. Su A.I., et al. A gene atlas of the mouse and human protein-encoding transcriptomes. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 6062-6067
11. Yamasaki C., et al. Investigation of protein functions through data-mining on integrated human transcriptome database, H-Invitational database (H-InvDB). Gene 364 (2005) 99-107
12. Grant S.G.N. An integrative neuroscience program linking genes to cognition and disease. In: Plomin R., et al. (Ed). Behavioral Genetics in the Postgenomic Era (2003), American Psychological Association 123-138
13. Garlick D. Understanding the nature of the general factor of intelligence: the role of individual differences in neural plasticity as an explanatory mechanism. Psychol. Rev. 109 (2002) 116-136
14. Deary I. Looking Down on Human Intelligence: From Psychometrics to the Brain (2000), Oxford University Press
15. Pocklington, A.J. et al. (2006) The proteomes of neurotransmitter receptor complexes form modular networks with distributed functionality underlying plasticity and behaviour. Mol. Syst. Biol. doi:10.1038/msb4100041
16. Dehaene S., et al. Three parietal circuits for number processing. Cogn. Neuropsychol. 20 (2003) 487-506
17. Stanesku-Cosson, et al. Understanding dissociations in dyscalculia. A brain imaging study of the impact of number size on the cerebral networks for exact and approximate calculation. Brain 123 (2000) 2240-2255
18. Eger E., et al. A supramodal number representation in human intraparietal cortex. Neuron 37 (2003) 719-725
19. Dehaene S., et al. Arithmetic and the brain. Curr. Opin. Neurobiol. 14 (2004) 218-224
20. Pinel P., et al. Distributed and overlapping cerebral representations of number, size, and luminance during comparative judgments. Neuron 41 (2004) 983-993
21. Shuman M., and Kanwisher N. Numerical magnitude in the human parietal lobe: tests of representational generality and domain specificity. Neuron 44 (2004) 557-569
22. Molko N., et al. Functional and structural alterations of the intraparietal sulcus in a developmental dyscalculia of genetic origin. Neuron 40 (2003) 847-858
23. Göbel S.M., et al. Response-selection-related parietal activation during number comparison. J. Cogn. Neurosci. 16 (2004) 1536-1551
24. Dehaene S., et al. Sources of mathematical thinking: behavioral and brain-imaging evidence. Science 284 (1999) 970-974
25. Thiebaut de Schotten M., et al. Direct evidence of a parietal-frontal pathway subserving spatial awareness in humans. Science 309 (2005) 2226-2228
26. Gaffan D. Widespread cortical networks underlie memory and attention. Science 309 (2005) 2172-2173
27. David S.P., et al. Ventral striatum/nucleus accumbens activation to smoking-related pictorial cues in smokers and nonsmokers: a functional magnetic resonance imaging study. Biol. Psychiatry 58 (2005) 488-494
28. Butcher, L.M. et al. Generalist genes and cognitive neuroscience. Curr. Opin. Neurobiol. (in press)
29. Plomin R., et al. The genetic basis of complex human behaviors. Science 264 (1994) 1733-1739