Dynamic culture in a rotating-wall vessel bioreactor differentially inhibits murine T-lymphocyte activation by mitogenic stimuli upon return to static conditions in a time-dependent manner

Journal of Applied Physiology

Volumn 100, Issue 4, 2006, Pages 1287-1292

  Simons, D M ^a   Gardner, E M ^a   Lelkes, P I ^a  

^a DREXEL UNIVERSITY   (United States)

Author keywords

Immune response; Microgravity; Spaceflight

Indexed keywords

CONCANAVALIN A; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOREACTOR; CELL CULTURE; CELL DEATH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNE RESPONSE; MICROGRAVITY; MITOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPACE FLIGHT; T LYMPHOCYTE ACTIVATION; UPREGULATION;

ANIMALS; BIOREACTORS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CONCANAVALIN A; INTERLEUKIN-2; KINETICS; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED BALB C; MITOGENS; ROTATION; SPLEEN; T-LYMPHOCYTES; WEIGHTLESSNESS SIMULATION;

EID: 33646346605     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00887.2005     Document Type: Article

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