Role of intracellular Ca2+ and pH in positive inotropic response of cardiomyocytes to diacylglycerol

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 275, Issue 4 44-4, 1998, Pages

  Yeqing, P I ^a,b   Walker, Jeffery W ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b Dept of Physiology ^*  (United States)

Author keywords

Excitation contraction coupling; Fluorescent indicators; Sodium hydrogen antiport; Ventricular cells

Indexed keywords

CALCIUM; PROTEIN KINASE C; 1,2-DIOCTANOYLGLYCEROL; 5 (N ETHYL N ISOPROPYL)AMILORIDE; AMILORIDE; ANTIARRHYTHMIC AGENT; DIACYLGLYCEROL; DIOCTANOIN; DRUG DERIVATIVE; FLUORESCENT DYE;

ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; ENZYME ACTIVITY; EXCITATION CONTRACTION COUPLING; HEART CONTRACTION; HEART MUSCLE CELL; INOTROPISM; MALE; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; RAT; SARCOPLASMIC RETICULUM; SIGNAL TRANSDUCTION; ANIMAL; CALIBRATION; CELL CULTURE; CYTOLOGY; DIASTOLE; DRUG EFFECT; ELECTROSTIMULATION; HEART MUSCLE; HEART VENTRICLE; METABOLISM; METHODOLOGY; PH; PHYSIOLOGY; SPECTROFLUOROMETRY; SYSTOLE; TIME;

AMILORIDE; ANIMALS; ANTI-ARRHYTHMIA AGENTS; CALCIUM; CALIBRATION; CELLS, CULTURED; DIASTOLE; DIGLYCERIDES; ELECTRIC STIMULATION; FLUORESCENT DYES; HEART VENTRICLES; HYDROGEN-ION CONCENTRATION; MALE; MYOCARDIAL CONTRACTION; MYOCARDIUM; RATS; SARCOPLASMIC RETICULUM; SPECTROMETRY, FLUORESCENCE; SYSTOLE; TIME FACTORS;

EID: 33646293466     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. + currents in rat ventricular myocytes. Proc, Natl. Acad. Sci. USA 85: 8756-8760, 1988.
2. Bassani, J. W. M., W. Yuan, and D. M. Bers. Fractional SR Ca release is regulated by trigger Ca and SR Ca content in cardiac myocytes. Am. J. Physiol. 268 (Cell Physiol. 37): C1313-C1329, 1995.
3. Borzak, S., R.A. Kelly, B. K. Krämer, Y. Matoba, J. D. Marsh, and M. Reers. In situ calibration of fura-2 and BCECF fluorescence in adult rat ventricular myocytes. Am. J. Physiol: 259 (Heart Circ. Physiol. 28): H973-H981, 1990.
4. Boyer, M. J., and D. W. Hedley. Measurement of cellular pH. Methods Cell Biol. 41: 135-148, 1994.
5. 2+ in adult rat cardiac myocytes. Circ. Res. 66: 1143-1155, 1990.
6. Clement, O., M. Puceat, M. P. Walsh, and G. Vassort. Protein kinase C enhances myosin light chain kinase effects on force development and ATPase activity in rat single skinned cardiac cells. Biochem. J. 285: 311-317, 1992.
7. Conforti, L., K. Sumi, and N. Sperelakis. Dioctanoyl-glycerol inhibits L-type calcium current in embryonic chick cardiomyocytes independent of protein kinase C activation. J. Mol. Cell. Cardiol. 27: 1219-1224, 1995.
8. Dosemeci, A., R. S. Dhallan, N. M. Cohen, W. J. Lederer, and T. B. Rogers. Phorbol ester increases calcium current and simulates the effects of angiotensin II on cultured neonatal rat heart myocytes. Circ. Res. 62: 347-352, 1988.
9. 2+ mediated through alpha- and beta-adrenoceptors. Circ. Res. 62: 247-265, 1988.
10. Frace, A. M., P. F. Mery, R. Fischmeister, and H. C. Hartzell. Rate-limiting steps in the beta-adrenergic stimulation of cardiac calcium current. J. Gen. Physiol. 101: 337-353, 1993.
11. 2+ in cardiac myocytes. Circ. Res. 71: 870-882, 1992.
12. Gwathmey, J. K., and R. J. Hajjar. Effect of protein kinase C activation on sarcoplasmic reticulum function and apparent myofibrillar Ca sensitivity in intact and skinned muscles from normal and diseased human myocardium. Circ. Res. 67: 744-752, 1990.
13. Hartzell, H. C., P. F. Mery, R. Fischmeister, and G. Szabo. Sympathetic regulation of cardiac calcium current is due exclusively to cAMP-dependent phosphorylation. Nature 351: 573-576, 1991.
14. Huang, X. P., R. Sreekumar, J. R. Patel, and J. W. Walker. Response of cardiac myocytes to a ramp increase of diacylglycerol generated by photolysis of a novel caged diacylglycerol. Biophys. J. 70: 2448-2457, 1996.
15. Karmazyn, M., J. E. Watson, and M. P. Moffat. Mechanisms for cardiac depression induced by phorbol myristate acetate in working rat hearts. Br. J. Pharmacol. 100: 826-830, 1990.
16. i, and contraction in ventricular myocytes. Am. J. Physiol. 265.(Heart Circ. Physiol. 34): H793-H800, 1993.
17. Koss, K. L., and E. G. Kranias. Phospholamban: a prominent regulator of myocardial contractility. Circ. Res. 79: 1059-1063, 1996.
18. Kramer, B. K., T. W. Smith, and R. A. Kelly. Endothelin and increased contractility in adult rat ventricular myocytes. Role of intracellular alkalosis induced by activation of the PKCdependent Na/H exchanger. Circ. Acs. 68: 269-279, 1991.
19. Kranias, E. G., and R. J. Solaro. Phosphorylation of troponin I and phospholamban during catecholamine stimulation of rabbit heart. Nature 298: 182-184, 1982.
20. 2+ channels. Nature 335: 249-251, 1988.
21. Lasley, R. D., M. A. Noble, K. L. Paulsen, and R. M. Mentzer, Jr. Adenosine attenuates phorbol ester-induced negative inotropic and vasoconstrictive effects in rat hearts. Am. J. Physiol. 266 (Heart Circ. Physiol. 35): H2159-H2166, 1994.
22. Lester, J. W., K. F. Gannaway, R. A. Reardon, L. D. Koon, and P. A. Hofmann. Effects of adenosine and protein kinase C Stimulation on mechanical properties of rat cardiac myocytes. Am. J. Physiol. 271 (Heart Circ. Physiol. 40): H1778-H1785, 1996.
23. Lokuta, A. J., T. B. Rogers, W. J. Lederer, and H. H. Valdivia. Modulation of cardiac ryanodine receptors of swine and rabbit by a phosphorylation-dephosphorylation mechanism. J. Physiol. (Lond.) 487: 609-622, 1995.
24. 2+ in isolated mammalian ventricular myocytes. J. Physiol. (Lond.) 444: 481-498, 1991.
25. + channel by protein kinase C. Czrc. Res. 75: 999-1005, 1994.
26. Pi, Y.-Q., R. Sreekumar, X. P. Huang, and J. W. Walker. Positive inotropy mediated by diacylglycerol in rat cardiac myocytes. Circ. Res. 81: 92-100, 1997.
27. Pi, Y.-Q., R. Sreekumar, X. P. Huang, and J. W. Walker. Diacylglycerol enhances excitation-contraction coupling in cardiac myocytes (Abstract). Biophys. J. 74: A352, 1998.
28. Puceat, M., and J. H. Brown. Protein kinase C in the heart. In: Protein Kinase C, edited by J. F. Kuo. New York: Oxford University Press, 1994, p. 249-268.
29. 1-Adrenoceptor and purinoceptor agonists modulate Na-H antiport in single cardiac cells. Am. J. Physiol. 264 (Heart Circ. Physiol. 33): H310-H319, 1993.
30. Puri, T. S., B. L. Gerhardstein, X.-L. Zhao, M. B. Ladner, and M. M. Hosey. Differential effects of subunit interactions on protein kinase A- and C-mediated phosphorylation of L-type calcium channels. Biochemistry 36: 9605-9615, 1997.
31. 2+ accumulation in cardiac sarcoplasmic reticulum. J. Biol. Chem. 265: 4302-4308, 1990.
32. Sardet, C., L. Counillon, A. Frachi, and J. Pouyssegur. Growth factors induce phosphorylation of the Na/H antiporter, a glycoprotein of 110 kD. Science 289: 637-726, 1990.
33. 2+ current: independent of protein kinase C activation. Am. J. Physlol. 270 (Cell Physiol. 39): C655-C662, 1996.
34. Spurgeon, H. A., W. H. DuBell, M. D. Stern, S. J. Sollot, D. Ziman, H. S. Silver-man, M. C. Capogrossi, A. Talo, and E. G. Lakatta. Cytosolic calcium and myofilaments in single rat cardiac myocytes achieve a dynamic equilibrium during twitch relaxation. J. Physlol. (Lond.) 447: 83-102, 1992.
35. Sugden, P. H., and M. A. Bogoyevitch. Intracellular signalling through protein kinases in the heart. Cardiovasc. Res. 30: 478-492, 1995.
36. Terzic, A., M. Puceat, O. Clement, F. Scamps, and G. Vassort. α-Adrenergic effects on intracellular pH and calcium and on myofilaments in single rat cardiac cells. J. Physiol. (Lond.) 447: 275-292, 1992.
37. Venema, R., and J. Kuo. Protein kinase C mediated phosphorylation of TnI and C-protein is associated with inhibition of actomyosin MgATPase. J. Biol. Chem. 268: 2705-2711, 1993.
38. i. J. Mol. Cell. Cardiol. 24: 937-948, 1992.
39. Watson, J. E., and M. Karmazyn. Concentration-dependent effects of protein kinase C-activating and non-activating phorbol esters on myocardial contractility, coronary resistance, energy metabolism, prostacyclin synthesis and ultrastructure in isolated rat hearts. Circ. Res. 69: 1114-1131, 1991.
40. Wegner, A., H. K. B. Simmcrman, J. P. Lindeman, and L. R. Jones. Phospholamban phosphorylation. Phosphorylation of serine 16 and threonine 17 in response to β-adrenergic stimulation. J. Biol. Chem. 264: 11468-11474, 1989.
41. Wier, W. G., and D. T. Yue. Intracellular calcium transients underlying the short-term force-interval relationship in ferret ventricular myocardium. J. Physiol. (Lond.) 376: 507-530, 1986.
42. Yuan, S., F. A. Sunahara, and A. K. Sen. Tumor-promoting phorbol esters inhibit cardiac functions and induce redistribution of protein kinase C in perfused beating rat heart. Circ. Res. 61: 372-378, 1987.