Intravenous cidofovir treatment for recalcitrant warts in the setting of a patient with myelodysplastic syndrome

Journal of the European Academy of Dermatology and Venereology

Volumn 20, Issue 2, 2006, Pages 202-205

  Grone D ^a   Treudler, R ^a   de Villiers, E M ^b   Husak, R ^a   Orfanos, C E ^a   Zouboulis, Ch C ^a,c  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c DESSAU MEDICAL CENTER   (Germany)

Author keywords

Antiviral; Cidofovir; Human papilloma virus; Myelodysplastic syndrome; Warts

Indexed keywords

AZACITIDINE; CARBON DIOXIDE; CIDOFOVIR; CYCLOSPORIN A; FLUOROURACIL; GRANULOCYTE COLONY STIMULATING FACTOR; IMIQUIMOD; LIQUID NITROGEN; PREDNISOLONE; PROBENECID; ANTIVIRUS AGENT; CYTOSINE; DRUG DERIVATIVE; PHOSPHONIC ACID DERIVATIVE;

ACANTHOSIS; ADULT; ARTICLE; CARBON DIOXIDE LASER; CASE REPORT; CAUCASIAN; CRYOTHERAPY; CYTOPATHOLOGY; DERMATOLOGY; FEMALE; FOLLOW UP; HEALING; HEMATOLOGIC DISEASE; HUMAN; HYPERKERATOSIS; KIDNEY DYSFUNCTION; MINIMAL RESIDUAL DISEASE; MYELODYSPLASTIC SYNDROME; NEUTROPENIA; PAPILLOMATOSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REFRACTORY ANEMIA; SKIN BIOPSY; THROMBOCYTE COUNT; VERRUCA VULGARIS; VIRUS IDENTIFICATION; WART VIRUS; DIFFERENTIAL DIAGNOSIS; HAND; INTRAVENOUS DRUG ADMINISTRATION; PATHOLOGY; SKIN DISEASE;

ADULT; ANTIVIRAL AGENTS; CYTOSINE; DIAGNOSIS, DIFFERENTIAL; FEMALE; HAND; HUMANS; INFUSIONS, INTRAVENOUS; MYELODYSPLASTIC SYNDROMES; PHOSPHONIC ACIDS; SKIN DISEASES; WARTS;

EID: 33646255453     PISSN: 09269959     EISSN: 14683083     Source Type: Journal    
DOI: 10.1111/j.1468-3083.2006.01380.x     Document Type: Article

References (18)

1. Ficarra G, Miliani A, Adler-Storthz K et al. Recurrent oral condylomata acuminata and hairy leukoplakia: An early sign of myelodysplastic syndrome in an HIV-seronegative patient. J Oral Pathol Med 1991; 20: 398-402.
2. Salamanchuk Z, Jakobczyk MG, Nowak WA, Skotnicki AB. Complex cytogenetics in a case of probably work-related MDS/AML. Leuk Res 2004; 28: 1357-1361.
3. Occhipinti E, Correa H, Yu L, Craver R. Comparison of two new classifications for pediatric myelodysplastic and myeloproliferative disorders. Pediatr Blood Cancer 2005; 44: 240-244.
4. Nebesio CL, Mirowski GW, Chuang TY. Human papillomavirus: Clinical significance and malignant potential. Int J Dermatol 2001; 40: 373-379.
5. Johnson JA, Gangemi JD. Selective inhibition of human papillomavirus-induced cell proliferation by (s)-1-[3-hydroxy-2(phosphonylmethoxy) propyl]cytosine. Antimicrob Agents Chemother 1999; 43: 1198-1205.
6. Zabawski EJ Jr, Cockerell CJ. Topical and intralesional cidofovir: A review of pharmacology and therapeutic effects. J Am Acad Dermatol 1998; 39: 741 -745.
7. Calista D. Topical cidofovir for severe cutaneous human papillomavirus and molluscum contagiosum infections in patients with HIV/AIDS. A pilot study. J Eur Acad Dermatol Venereol 2000; 14: 484-488.
8. Andrei G, Snoeck R, Schols D, De Clercq E. Induction of apoptosis by cidofovir in human papillomavirus (HPV)- positive cells. Oncol Res 2001; 12: 397-408.
9. Calista D. Resolution of recalcitrant human papillomavirus gingival infection with topical cidovovir. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000; 90: 713-715.
10. Snoeck R, Andrei G, De Clercq E. Cidofovir in the treatment of HPV-associated lesions. Verh K Acad Geneesk Belg 2001; 63: 93-120.
11. Snoeck R, Boosens M, Parent D et al. Phase II double-blind, placebo-controlled study of the safety and efficacy of cidofovir topical gel for the treatment of patients with human papillomavirus infection. Clin Infect Dis 2001; 33: 597-602.
12. Davis MD, Gostout BS, McGovern RM et al. Large plantar wart caused by human papillomavirus-66 and resolution by topical cidofovir therapy. J Am Acad Dermatol 2000; 43: 340-343.
13. Wilson WR, Hashemiyoon R, Hawrych A. Intralesional cidofovir for recurrent laryngeal papillomas: Preliminary report. Ear Nose Throat J 2000; 79: 236 -238.
14. Orlando G, Fasolo MM, Berett R et al. Intralesional or topical cidofovir for the treatment of recurrent genital warts in HIV-1-infected patients. AIDS 1999; 13: 1978-1980.
15. Husak R, Zouboulis CC, Sander-Bähr C, Hummel M, Orfanos CE. Refractory oral HPV papillomas treated topically with 1 to 3% cidofovir solutions in HIV-1-infected patients. Br J Dermatol 2005; 152: 590-591.
16. Hivnor C, Shepard JW, Shapiro MS, Vittorio CC. Intravenous cidofovir for recalcitrant verruca vulgaris in the setting of HIV. Arch Dermatol 2004; 140: 13-14.
17. Armbruster C, Kreuzer A, Vorbach H, Huber M, Armbruster C. Successful treatment of severe respiratory papillomatosis with intravenous cidofovir and interferon alpha-2b. Eur Respir J 2001; 17: 830-831.
18. Preiser W, Kapur N, Snoeck R, Groves RW, Brink NS. No apparent effect of cidofovir in epidermodysplasia verruciformis. J Clin Virol 2000; 16: 55-57.