CCR3 and eotaxin mRNA expression are upregulated in eosinophilic nasal polyps;Erhöhte CCR3- und eotaxin-mRNA-expression in eosinophilen nasenpolypen

Allergologie

Volumn 29, Issue 4, 2006, Pages 125-134

  Olze, H ^a,b   Forster U ^a   Krenn, V ^a   Morawietz, L ^a   Luger, E O ^a,c  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b Mitglied im Global Allergy and Asthma European Network (GA2LEN)   (Germany)

^c DEUTSCHES RHEUMA FORSCHUNGSZENTRUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR3; EOTAXIN; MESSENGER RNA; RANTES;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EOSINOPHIL; HISTOLOGY; HUMAN; HUMAN TISSUE; NOSE MUCOSA; NOSE POLYP; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RANK SUM TEST; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCORING SYSTEM; TURBINATE; UPREGULATION;

EID: 33646241298     PISSN: 03445062     EISSN: None     Source Type: Journal    
DOI: 10.5414/alp29125     Document Type: Article

References (48)

1. Allen J.S., R. Eisma, D. La Freniere: Characterization of the eosinophil chemokine RANTES in nasal polyps. Ann. Otol. Rhinol. Laryngol. 107, 416-420 (1998).
2. Bachert C., U. Hauser, B. Prem, C. Rudack: IL-5 synthesis is upregulated in human nasal polyp tissue. J. Allergy Clin. Immunol. 99, 837-842 (1997).
3. Bachert C., M. Wagenmann, C. Rudack, P. van Cauwenberge: The role of cytokines in infectious sinusitis and nasal polyposis. Allergy 53, 2-13 (1998).
4. Bachert C., P. Gevaert, G. Holtappels, C. Cuvelier, P. van Cauwenberge: Nasal polyposis: from cytokines to growth. Am. J. Rhinol. 14, 279-290 (2000).
5. Baggiolini M.: Chemokines and leukocyte traffic. Nature 392, 565-568 (1998).
6. Bartels J., S. Maune, J.E. Meyer et al.: Increased eotaxin-mRNA expression in non-atopic and atopic nasal polyps: comparison to RANTES and MCP-3 expression. Rhinology 35, 171-174 (1997).
7. Bocchino V., G. Bertorelli, C.P. Bertrand, P.D. Ponath, D. Olivieri: Eotaxin and CCR3 arc up-regulated in exacerbations of chronic bronchitis. Allergy 57, 17-22 (2002).
8. Caversaccio M., A. Hartnell, D. Calnan et al.: The role of chemokines in nasal polyps. Schweiz. Med. Wochenschr. 125 (Suppl.), 92-95 (2000).
9. Caversaccio M., M. Uguccioni, A. Hartnell, D. Conroy: Chronic immunological rhinosinusitis: general aspects, cytokines, chemokines and possibile therapeutic consequences. Otorhinolaryngol. Nova 12, 52-62 (2003).
10. Chomczynski P., N. Sacci: Single-step method of RNA isolation by guanidine thicyanat-phenol-chloroform extraction. Anal. Biochem. 162, 156-159 (1987).
11. Dulkys Y., G. Schramm, D. Kimmig et al.: Detection of mRNA for eotaxin-2 and eotaxin-3 in human dermal fibroblasts and their distinct activation profile on human eosinophils. J. Invest. Dermatol. 116, 498-505 (2001).
12. Ebisawa M., T. Yamada, C. Bickel, D. Klunk, R.P. Schleimer: Eosinophil transendothelial migration induced by cytokines. III. Effect of the chemokine RANTES. J. Immunol. 153, 2153-2160 (1994).
13. Elsner J., A. Kapp: The chemokine network in eosinophil activation. Allergy Asthma Proc. 22, 139-148 (2001).
14. Elsner J., A. Kapp: Aktivierung und Modulation eosinophiler Granulozyten durch Chemokine. Allergologie 24, 368-389 (2001).
15. Fokkens W., A. Holm, E. Rijntes, P. Mulder, T. Vroom: Characterization and quantification of cellular infiltrates in nasal mucosa of patients with grass pollen allergy, non-allergic patients with nasal polyps and controls. Int. Arch. Allergy Immunol. 93, 66-72 (1990).
16. Forssmann U., P. Uguccioni, C.A. Loetscher, H. Dahinden, M. Baggiolini: Eotaxin-2, a novel CC chemokine that is selective for the chemokine receptor CCR3, and acts like eotaxin on human eosinophil and basophil leukocytes. J. Exp. Med. 185, 2171-2176 (1997).
17. Gerber B.O., M.P. Zanni, M. Uguccioni, N. Yawalkar, M. Maggiolini, B. Moser: Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils. Curr. Biol. 7, 836-843 (1997).
18. Giampiero P., B. Paolo, N. Eleonora, S. Domenico, T. Giuseppe, F. Guiseppa, P.L. Rita, F. Giovanna: Intranasal treatment with lysine acetylsalicylate in patients with nasal polyposis. Ann. Allergy 67, 588-592 (1991).
19. Hamilos D.L., D.Y. Leung, D.P. Huston et al.: GM-CSF, IL-5 and RANTES immunoreactivity and mRNA expression in chronic hyperplastic sinusitis with nasal polyposis (NP). Clin. Exp. Allergy 28, 1145-1152 (1998).
20. Ishida K., B.L. Zhu, H. Maeda: Novel approach to quantitative reverse transcription PCR assay of mRNA component in autopsy material using the TaqMan fluorogenic detection system: dynamics of pulmonary surfactant apoprotein A. Forensic Sci. Int. 113, 127-131 (2000).
21. Jahnsen F.L., R. Haye, E. Gran, P. Brandtzaeg, F.E. Johansen: Glucocorticosteroids inhibit mRNA expression for eotaxin, eotaxin-2, and monocytechemotactic protein-4 in human airway inflammation with eosinophilia. J. Immunol. 163, 1545-1551 (1999).
22. Jose P.J., D.A. Griffits-Johnson, P.D. Collins et al.: Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation. J. Exp. Med. 179, 881-887 (1993).
23. Kaldenbuch T., D. Schäfer, J. Gosepath, F. Bittinger, L. Klimek, W.J. Mann: Die Bedeutung eosinophiler Granulozyten in Beziehung zu Allergie und Aspirin-Intoleranz bei Patienten mit Sinusitis polyposa. Laryngo-Rhino-Otol. 78, 429-433 (1999).
24. Kapp A., G. Zeck-Kapp, W. Czech, E. Schöpf: The chemokine RANTES is more than a chemoattractant: characterization of its effect on human eosinophil oxidative metabolism and morphology in comparison with IL-5 and GM-CSF. J. Invest. Dermatol. 102, 906-914 (1994).
25. Kitaura M., T. Nakajama, T. Imai et al.: Molecular cloning of human eotaxin, an eosinophil-specific CC chemokine, and identification of a specific receptor. CC chemokine receptor 3. J. Biol. Chem. 271, 7725-7730 (1996).
26. Kitaura M., N. Suzuki, T. Imai et al.: Molecular cloning of a novel human CC chemokine (Eotaxin-3) that is a functional ligand of CC chemokine receptor 3. J. Biol. Chem. 274, 27975-27980 (1999).
27. Lee C.H., C.S. Rhee, Y.G. Min: Cytokine gene expression in nasal polyps. Ann. Otol. Rhinol. Laryngol. 107, 665-670 (1998).
28. Leutenegger C.M., C.N. Mislin, B. Sigrist et al.: Quantitative real-time PCR for the measurement of feline cytokine mRNA. Vet. Immunol. Immunopathol. 71, 291-305 (1999).
29. Lund V.J., I.S. Mackay: Staging in rhinosinusitis. Rhinology 31, 183-184 (1993).
30. Luster A.D.: Chemokines-chemotactic cytokines that mediate inflammation. N. Engl. J. Med. 338, 436-445 (1998).
31. Minshall E.M., L., Cameron, F. Lavigne et al.: Eotaxin mRNA and protein expression in chronic sinusitis and allergen-induced nasal responses in seasonal allergic rhinitis. Am. J. Respir. Cell Mol. Biol. 17, 683-690 (1997).
32. Maune S., J.E. Meyer: The role of CC chemokines in chronic sinusitis. Otorhinolaryngol. Nova 12, 63-70 (2003).
33. Moneret-Vautrin D.A., V. Hsieh, W. Wayoff, J.L. Guyot, C. Mouton, Y. Maria: Nonallergic rhinitis with eosinophilia syndrome a precursor of the triad: nasal polyposis, intrinsic asthma, and intolerance to aspirin. Ann. Allergy 64, 513-518 (1990).
34. Naclerio R. M.: Pathophysiology of perennial allergic rhinitis. Allergy 52 (Suppl. 36), 7-13 (1997).
35. Nonaka M., R. Pawankar, F. Saji, T. Yagi: Eotaxin synthesis by nasal polyp fibroblasts. Acta Otolaryngol. 119, 816-820 (1999).
36. Pods R., D. Ross, S. van Hulst et al.: RANTES, eotaxin and eotaxin-2 expression and production in patients with aspirin triad. Allergy 58, 1165-1170 (2003).
37. Ponath P.D., S. Qin, D.J. Ringler et al.: Cloning of the human eosinophil chemoattractant eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils. J. Clin. Invest. 97, 604-612 (1996).
38. Rudack C., C. Bachert: Zytokine und Chemokine bei Nasennebenhö hlenerkrankungen. Laryngo-Rhino-Otol. 78, 481-490 (1999).
39. Schleimer R.P., S.A. Sterbinsky, J. Kaiser, C.A. Bickel, D.A. Klunk, K. Tomioka, W. Newman, F.W. Luscinskas, M.J. Gimbrone, B.W. McIntyre: IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium. Association with expression of VCAM-1. J. Immunol. 148, 1086-1092 (1992).
40. Sehmi R., O. Cromwell, J. Wardlaw, R. Moqbel, B. Kay: Interleukin-8 is a chemoattractant for eosinophils purified from subjects with a blood eosinophilia but not from healthy subjects. Clin. Exp. Allergy 23, 1027-1031 (1994).
41. Shin S.H., Y.J. Park, C.H. Jeon et al.: Quantitative analysis of eotaxin and RANTES messenger RNA in nasal polyps: association of tissue and nasal eosinophils. Laryngoscope 110, 1353-1357 (2000).
42. Shinkai A., H. Yoshisue, M. Koike, E. Shoji, S. Nakagawa, T. Nishi: A novel human CC-chemokine, eotaxin-3, which is expressed in IL-4-stimulated vascular endothelial cells, exhibits potent activity toward eosinophils. J. Immunol. 163, 1602-1610 (1999).
43. Sladek K., R. Dworski, G.A. Fitzgerald, K.L. Buitkus, F.J. Block, S.R. Marney Jr., R. Sheller: Allergen-stimulated release of thromboxane A2 and leukotriene E4 in humans. Effect of indomethacin. Am. Rev. Respir. Dis. 141, 1441-1445 (1990).
44. Terada N., K. Maesako, N. Hamano et al.: Eosinophil adhesion regulates RANTES production in nasal epithelial cells. J. Immunol. 158, 5464-5470 (1997).
45. Terada N., N. Hamano, W.J. Kim: The kinetics of allergen-induced eotaxin level in nasal lavage fluid: its key role in eosinophil recruitment in nasal mucosa. Am. J. Respir. Crit. Care Med. 164, 575-579 (2001).
46. Till S., L. Jopling, P. Wachholz, S. Durham, I. Sabroe: T cell phenotypes of the normal nasal mucosa: induction of Th2 cytokines and CCR3 expression by IL-4. J. Immunol. 166, 2303-2310 (2001).
47. Yawalkar N., M. Uguccioni, J. Scharer, M. Baggioline: Enhanced expression of eotaxin and CCR3 in atopic dermatitis. J. Invest. Dermatol. 113, 43-48 (1999).
48. Ying S., Q. Meng, K. Zeibecoglou et al.: Eosinophil chemotactic chemokines (eotaxin, eotaxin-2, RANTES, monocyte chemoattractant protein-3 (MCP-3) and MCP-4), and C-C chemokine receptor 3 expression in bronchial biopsies from atopic and nonatopic (intrinsic) asthmatics. J. Immunol. 163, 6321-6329 (1999).