Specific role of the SR protein splicing factor B52 in cell cycle control in Drosophila

Molecular and Cellular Biology

Volumn 26, Issue 9, 2006, Pages 3468-3477

  Rasheva, Vanya I ^a   Knight, David ^a   Bozko, Przemyslaw ^a   Marsh, Katherine ^a   Frolov, Maxim V ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DOUBLE STRANDED RNA; GENOMIC DNA; MESSENGER RNA; PROTEIN; SR PROTEIN SPLICING FACTOR B52; TRANSCRIPTION FACTOR E2F; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE; DROSOPHILA; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROCESSING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING;

ANIMALS; CELL CYCLE; DOWN-REGULATION; DROSOPHILA; DROSOPHILA PROTEINS; E2F2 TRANSCRIPTION FACTOR; EYE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MUTATION; NUCLEAR PROTEINS; PHENOTYPE; PHOSPHOPROTEINS; RNA SPLICING; RNA, MESSENGER; S PHASE; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 33646231790     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.26.9.3468-3477.2006     Document Type: Article

References (50)

1. Ajuh, P., B. Kuster, K. Panov, J. C. Zomerdijk, M. Mann, and A. I. Lamond. 2000. Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry. EMBO J. 19:6569-6581.
2. Ben-Yehuda, S., I. Dix, C. S. Russell, M. McGarvey, J. D. Beggs, and M. Kupiec. 2000. Genetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae. Genetics 156:1503-1517.
3. Ben-Yehuda, S., C. S. Russell, I. Dix, J. D. Beggs, and M. Kupiec. 2000. Extensive genetic interactions between PRP8 and PRP17/CDC40, two yeast genes involved in pre-mRNA splicing and cell cycle progression. Genetics 154:61-71.
4. Ben-Yehuda, S., I. Dix, C. S. Russell, S. Levy, J. D. Beggs, and M. Kupiec. 1998. Identification and functional analysis of hPRP17, the human homologue of the PRP17/CDC40 yeast gene involved in splicing and cell cycle control. RNA 4:1304-1312.
5. Blais, A., and B. D. Dynlacht. 2004. Hitting their targets: an emerging picture of E2F and cell cycle control. Curr. Opin. Genet. Dev. 14:527-532.
6. Blanchette, M., R. E. Green, S. E. Brenner, and D. C. Rio. 2005. Global analysis of positive and negative pre-mRNA splicing regulators in Drosophila. Genes Dev. 19:1306-1314.
7. Bosco, G., W. Du, and T. L. Orr-Weaver. 2001. DNA replication control through interaction of E2F-RB and the origin recognition complex. Nat. Cell Biol. 3:289-295.
8. Brook, A., J.-E. Xie, W. Du, and N. Dyson. 1996. Requirements for dE2F function in proliferating cells and in post-mitotic differentiating cells. EMBO J. 15:3676-3683.
9. Burns, C. G., R. Ohi, S. Mehta, E. T. O'Toole, M. Winey, T. A. Clark, C. W. Sugnet, M. Ares, Jr., and K. L. Gould. 2002. Removal of a single α-tubulin gene intron suppresses cell cycle arrest phenotypes of splicing factor mutations in Saccharomyces cerevisiae. Mol. Cell. Biol. 22:801-815.
10. Cam, H., and B. D. Dynlacht. 2003. Emerging roles for E2F: beyond the G1/S transition and DNA replication. Cancer Cell 3:311-316.
11. Cayirlioglu, P., P. C. Bonnette, M. R. Dickson, and R. J. Duronio. 2001. Drosophila E2f2 promotes the conversion from genomic DNA replication to gene amplification in ovarian follicle cells. Development 128:5085-5098.
12. Cayirlioglu, P., and R. J. Duronio. 2001. Cell cycle: flies teach an old dogma new tricks. Curr. Biol. 11:R178-R181.
13. Champlin, D. T., M. Frasch, H. Saumweber, and J. T. Lis. 1991. Characterization of a Drosophila protein associated with boundaries of transcriptionally active chromatin. Genes Dev. 5:1611-1621.
14. Dahan, O., and M. Kupiec. 2004. The Saccharomyces cerevisiae gene CDC40/PRP17 controls cell cycle progression through splicing of the ANC1 gene. Nucleic Acids Res. 32:2529-2540.
15. Dimova, D., O. Stevaux, M. V. Frolov, and N. J. Dyson. 2003. Cell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway. Genes Dev. 17:2308-2320.
16. Dimova, D. K., and N. J. Dyson. 2005. The E2F transcriptional network: old acquaintances with new faces. Oncogene 24:2810-2826.
17. Du, W., M. Vidal, J.-E. Xie, and N. Dyson. 1996. RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila. Genes Dev. 10:1206-1218.
18. Du, W., J.-E. Xie, and N. Dyson. 1996. Ectopic expression of dE2F and dDP induces cell proliferation and death in the Drosophila eye. EMBO J. 15:3684-3692.
19. Duronio, R. J., P. H. O'Farrell, J.-E. Xie, A. Brook, and N. Dyson. 1995. The transcription factor E2F is required for S phase during Drosophila embryogenesis. Genes Dev. 9:1445-1455.
20. Dynlacht, B. D., A. Brook, M. S. Dembski, L. Yenush, and N. Dyson. 1994. DNA-binding and trans-activation properties of Drosophila E2F and DP proteins. Proc. Natl. Acad. Sci. USA 91:6359-6363.
21. Dyson, N. 1998. The regulation of E2F by pRB-family proteins. Genes Dev. 12:2245-2262.
22. Frolov, M. V., D. S. Huen, O. Stevaux, D. Dimova, K. Balczarek-Strang, M. Elsdon, and N. J. Dyson. 2001. Functional antagonism between E2F family members. Genes Dev. 15:2146-2160.
23. Frolov, M. V., N. S. Moon, and N. J. Dyson. 2005. dDP is needed for normal cell proliferation. Mol. Cell. Biol. 25:3027-3039.
24. Frolov, M. V., O. Stevaux, N. S. Moon, D. Dimova, E. J. Kwon, E. J. Morris, and N. J. Dyson. 2003. G1 cyclin-dependent kinases are insufficient to reverse dE2F2-mediated repression. Genes Dev. 17:723-728.
25. Graveley, B. R., K. J. Hertel, and T. Maniatis. 1999. SR proteins are 'locators' of the RNA splicing machinery. Curr. Biol. 9:R6-R7.
26. Hertel, K. J., and B. R. Graveley. 2005. RS domains contact the pre-mRNA throughout spliceosome assembly. Trends Biochem. Sci. 30:115-118.
27. Hoffman, B. E., and J. T. Lis. 2000. Pre-mRNA splicing by the essential Drosophila protein B52: tissue and target specificity. Mol. Cell. Biol. 20:181-186.
28. Kim, S., H. Shi, D. K. Lee, and J. T. Lis. 2003. Specific SR protein-dependent splicing substrates identified through genomic SELEX. Nucleic Acids Res. 31:1955-1961.
29. Lemaire, R., J. Prasad, T. Kashima, J. Gustafson, J. L. Manley, and R. Lafyatis. 2002. Stability of a PKCI-1-related mRNA is controlled by the splicing factor ASF/SF2: a novel function for SR proteins. Genes Dev. 16:594-607.
30. Li, X., J. Wang, and J. L. Manley. 2005. Loss of splicing factor ASF/SF2 induces G2 cell cycle arrest and apoptosis, but inhibits internucleosomal DNA fragmentation. Genes Dev. 19:2705-2714.
31. Logan, N., A. Graham, X. Zhao, R. Fisher, B. Maiti, G. Leone, and N. B. La Thangue. 2005. E2F-8: an E2F family member with a similar organization of DNA-binding domains to E2F-7. Oncogene 24:5000-5004.
32. Maiti, B., J. Li, A. de Bruin, F. Gordon, C. Timmers, R. Opavsky, K. Patil, J. Tuttle, W. Cleghorn, and G. Leone. 2005. Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation. J. Biol. Chem. 280:18211-18220.
33. Mayeda, A., A. M. Zahler, A. R. Krainer, and M. B. Roth. 1992. Two members of a conserved family of nuclear phosphoproteins are involved in pre-mRNA splicing. Proc. Natl. Acad. Sci. USA 89:1301-1304.
34. Neufeld, T. P., A. F. A. de la Cruz, L. A. Johnston, and B. A. Edgar. 1998. Coordination of cell growth and division by Drosophila E2F. Cell 93:1183-1193.
35. Newsome, T. P., B. Asling, and B. J. Dickson. 2000. Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics. Development 127:851-860.
36. Nurse, P., P. Thuriaux, and K. Nasmyth. 1976. Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe. Mol. Gen. Genet. 146:167-178.
37. Ohtani, K., and J. R. Nevins. 1994. Functional properties of a Drosophila homolog of the E2F1 gene. Mol. Cell. Biol. 14:1603-1612.
38. Parks, A. L., K. R. Cook, M. Belvin, N. A. Dompe, R. Fawcett, K. Huppert, L. R. Tan, C. G. Winter, K. P. Bogart, J. E. Deal, M. E. Deal-Herr, D. Grant, M. Marcinko, W. Y. Miyazaki, S. Robertson, K. J. Shaw, M. Tabios, V. Vysotskaia, L. Zhao, R. S. Andrade, K. A. Edgar, E. Howie, K. Killpack, B. Milash, A. Norton, D. Thao, K. Whittaker, M. A. Winner, L. Friedman, J. Margolis, M. A. Singer, C. Kopczynski, D. Curtis, T. C. Kaufman, G. D. Plowman, G. Duyk, and H. L. Francis-Lang. 2004. Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome. Nat. Genet. 36:288-292.
39. Ring, H. Z., and J. T. Lis. 1994. The SR protein B52/SRp55 is essential for Drosophila development. Mol. Cell. Biol. 14:7499-7506.
40. Royzman, I., A. J. Whittaker, and T. L. Orr-Weaver. 1997. Mutations in Drosophila DP and E2F distinguish G1-S progression from an associated transcriptional program. Genes Dev. 11:1999-2011.
41. Russell, C. S., S. Ben-Yehuda, I. Dix, M. Kupiec, and J. D. Beggs. 2000. Functional analyses of interacting factors involved in both pre-mRNA splicing and cell cycle progression in Saccharomyces cerevisiae. RNA 6:1565-1572.
42. Sawado, T., M. Yamaguchi, Y. Nishimoto, K. Ohno, K. Sakaguchi, and A. Matsukage. 1998. dE2F2, a novel E2F-family transcription factor in Drosophila melanogaster. Biochem. Biophys. Res. Commun. 251:409-415.
43. Seghezzi, W., K. Chua, F. Shanahan, O. Gozani, R. Reed, and E. Lees. 1998. Cyclin E associates with components of the pre-mRNA splicing machinery in mammalian cells. Mol. Cell. Biol. 18:4526-4536.
44. Stevaux, O., D. Dimova, M. V. Frolov, B. Taylor-Harding, E. Morris, and N. J. Dyson. 2002. Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2. EMBO J. 21:4927-4937.
45. Stevaux, O., D. K. Dimova, J. Y. Ji, N. S. Moon, M. V. Frolov, and N. J. Dyson. 2005. Retinoblastoma family 2 is required in vivo for the tissue-specific repression of dE2F2 target genes. Cell Cycle 4:1272-1280.
46. Tapon, N., K. F. Harvey, D. W. Bell, D. C. Wahrer, T. A. Schiripo, D. A. Haber, and I. K. Hariharan. 2002. Salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell 110:467-478.
47. Taylor-Harding, B., U. K. Binne, M. Korenjak, A. Brehm, and N. J. Dyson. 2004. p55, the Drosophila ortholog of RbAp46/RbAp48, is required for the repression of dE2F2/RBF-regulated genes. Mol. Cell. Biol. 24:9124-9136.
48. Trimarchi, J. M., and J. A. Lees. 2002. Sibling rivalry in the E2F family. Nat. Rev. Mol. Cell. Biol. 3:11-20.
49. Vgayraghavan, U., M. Company, and J. Abelson. 1989. Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae. Genes Dev. 3:1206-1216.
50. Wu, L., C. Timmers, B. Maiti, H. I. Saavedra, L. Sang, G. T. Chong, F. Nuckolls, P. Giangrande, F. A. Wright, S. J. Field, M. E. Greenberg, S. Orkin, J. R. Nevins, M. L. Robinson, and G. Leone. 2001. The E2F1-3 transcription factors are essential for cellular proliferation. Nature 414:457-462.