-
1
-
-
33646245228
-
-
(Sanofi-Aventis). Peptides having a bradykinin-inhibiting activity. AU 8939431, EP 0370453, JP 1990184697
-
Henke, S., Anagnostopulos, H., Breipohl, G., Knolle, J., Stechel, J., Schölkens, B., Fehlhaber, H.-W. (Sanofi-Aventis). Peptides having a bradykinin-inhibiting activity. AU 8939431, EP 0370453, JP 1990184697.
-
-
-
Henke, S.1
Anagnostopulos, H.2
Breipohl, G.3
Knolle, J.4
Stechel, J.5
Schölkens, B.6
Fehlhaber, H.-W.7
-
2
-
-
33646271998
-
-
(Sanofi-Aventis Deutschland GmbH). Peptides having bradykinin antagonist action. DE 3938751, US 5648333
-
Henke, S., Anagnostopulos, H., Breipohl, G., Knolle, J., Steehl, J., Schölkens, B., Fehlhaber, H.-W., Gerhards, H., Hock, F. (Sanofi-Aventis Deutschland GmbH). Peptides having bradykinin antagonist action. DE 3938751, US 5648333.
-
-
-
Henke, S.1
Anagnostopulos, H.2
Breipohl, G.3
Knolle, J.4
Steehl, J.5
Schölkens, B.6
Fehlhaber, H.-W.7
Gerhards, H.8
Hock, F.9
-
4
-
-
0033852880
-
2 receptor as a potential therapeutic target
-
2 receptor as a potential therapeutic target. Drug News Perspect 2000, 13: 213-25.
-
(2000)
Drug News Perspect
, vol.13
, pp. 213-225
-
-
Heitsch, H.1
-
5
-
-
0026556434
-
Bioregulation of kinins: Kallikreins, kininogens, and kininases
-
Bhoola, K.D., Figueroa, C.D., Worthy, K. Bioregulation of kinins: Kallikreins, kininogens, and kininases. Pharmacol Rev 1992,44: 1-80.
-
(1992)
Pharmacol Rev
, vol.44
, pp. 1-80
-
-
Bhoola, K.D.1
Figueroa, C.D.2
Worthy, K.3
-
6
-
-
0018995127
-
Pharmacology of bradykinin and related kinins
-
Regoli, D., Babare, J. Pharmacology of bradykinin and related kinins. Pharmacol Rev 1980, 32: 1-46.
-
(1980)
Pharmacol Rev
, vol.32
, pp. 1-46
-
-
Regoli, D.1
Babare, J.2
-
7
-
-
0025367711
-
Kinin receptor subtypes
-
Regoli, D., Rhaleb, N.E., Drapeau, G., Dion, S. Kinin receptor subtypes. J Cardiovasc Pharmacol 1990, 15(Suppl. 6): S30-8.
-
(1990)
J Cardiovasc Pharmacol
, vol.15
, Issue.SUPPL. 6
-
-
Regoli, D.1
Rhaleb, N.E.2
Drapeau, G.3
Dion, S.4
-
8
-
-
0002930001
-
Regulation of bradykinin action at the receptor level
-
Röscher, A.A., Klier, C., Dengler, D., Faussner, A., Muller-Esterl, W. Regulation of bradykinin action at the receptor level. J Cardiovasc Pharmacol 1990, 15(Suppl. 6): S39-43.
-
(1990)
J Cardiovasc Pharmacol
, vol.15
, Issue.SUPPL. 6
-
-
Röscher, A.A.1
Klier, C.2
Dengler, D.3
Faussner, A.4
Muller-Esterl, W.5
-
9
-
-
0026721649
-
Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor
-
Hess, J.F., Borkowski, J.A., Young, G.S., Strader, D., Ransom, R.W. Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor. Biochem Biophys Res Commun 1992, 184: 260-8.
-
(1992)
Biochem Biophys Res Commun
, vol.184
, pp. 260-268
-
-
Hess, J.F.1
Borkowski, J.A.2
Young, G.S.3
Strader, D.4
Ransom, R.W.5
-
10
-
-
0028065140
-
1 receptor
-
1 receptor. J Biol Chem 1994, 269: 21583-6.
-
(1994)
J Biol Chem
, vol.269
, pp. 21583-21586
-
-
Menke, J.G.1
Borkowski, J.A.2
Bierilo, K.K.3
McNeil, T.4
Derrick, A.W.5
Schneck, K.A.6
Ransom, R.W.7
Strader, C.D.8
Linemeyer, D.L.9
Hess, J.F.10
-
11
-
-
0031013519
-
Bradykinin receptors
-
Hall, JM Bradykinin receptors. Gen Pharmacol 1997, 28: 1-6.
-
(1997)
Gen Pharmacol
, vol.28
, pp. 1-6
-
-
Hall, J.M.1
-
12
-
-
10644286657
-
The pathophysiology of hereditary angioedema
-
Davis, A.E. III. The pathophysiology of hereditary angioedema. Clin Immunol 2005, 114: 3-9.
-
(2005)
Clin Immunol
, vol.114
, pp. 3-9
-
-
Davis III, A.E.1
-
13
-
-
10444243236
-
Current and future therapy for hereditary angioedema
-
Zuraw, B.L. Current and future therapy for hereditary angioedema. Clin Immunol 2005, 114: 10-6.
-
(2005)
Clin Immunol
, vol.114
, pp. 10-16
-
-
Zuraw, B.L.1
-
14
-
-
0028860711
-
Kinin receptor antagonists. Unique probes in basic and clinical research
-
Wirth, K.J., Heitsch, H., Scholkens, B. Kinin receptor antagonists. Unique probes in basic and clinical research. Can J Physiol Pharmacol 1995, 73: 797-804.
-
(1995)
Can J Physiol Pharmacol
, vol.73
, pp. 797-804
-
-
Wirth, K.J.1
Heitsch, H.2
Scholkens, B.3
-
15
-
-
0024152111
-
Kinin formation: Mechanism and role in inflammatory disorders
-
Proud, D., Kaplan, A.P. Kinin formation: Mechanism and role in inflammatory disorders. Annu Rev Immunol 1988, 6: 49-83.
-
(1988)
Annu Rev Immunol
, vol.6
, pp. 49-83
-
-
Proud, D.1
Kaplan, A.P.2
-
16
-
-
0026323110
-
Pain and hyperalgesia after intradermal injection of bradykinin in humans
-
Manning, D.C., Raja, S.N., Meyer, R.A., Campbell, J.N. Pain and hyperalgesia after intradermal injection of bradykinin in humans. Clin Pharmacol Ther 1991, 50: 721-9.
-
(1991)
Clin Pharmacol Ther
, vol.50
, pp. 721-729
-
-
Manning, D.C.1
Raja, S.N.2
Meyer, R.A.3
Campbell, J.N.4
-
17
-
-
0027200783
-
Sensory neuropeptide release by bradykinin: Mechanisms and pathophysiological implications
-
Gepetti, P. Sensory neuropeptide release by bradykinin: Mechanisms and pathophysiological implications. Regul Pept 1993,47: 1-23.
-
(1993)
Regul Pept
, vol.47
, pp. 1-23
-
-
Gepetti, P.1
-
18
-
-
0026667830
-
Effect of the bradykinin antagonist HOE 140 in experimental acute pancreatitis
-
Griesbacher, T., Lembeck, F. Effect of the bradykinin antagonist HOE 140 in experimental acute pancreatitis. Br J Pharmacol 1992, 107: 356-60.
-
(1992)
Br J Pharmacol
, vol.107
, pp. 356-360
-
-
Griesbacher, T.1
Lembeck, F.2
-
19
-
-
0027227387
-
Additive effects of the bradykinin antagonist, NPC 17761, and a leumedin, APC 15669, on survival in animal models of sepsis
-
Otterbein, L., Lowe, V.C., Kyle, D.J., Noronha-Blob, L. Additive effects of the bradykinin antagonist, NPC 17761, and a leumedin, APC 15669, on survival in animal models of sepsis. Agents Actions 1993, 39: C125-7.
-
(1993)
Agents Actions
, vol.39
-
-
Otterbein, L.1
Lowe, V.C.2
Kyle, D.J.3
Noronha-Blob, L.4
-
20
-
-
0031716315
-
Traumatic brain contusions. A clinical role for the kinin antagonist CP-0127
-
Narotam, P.K., Rodell, T., Nadvi, S.S., Bhoola, K.D., Troha, J.M., Parbhoosingh, R., van Dellen, J.R. Traumatic brain contusions. A clinical role for the kinin antagonist CP-0127. Acta Neurochir 1998, 140: 793-802.
-
(1998)
Acta Neurochir
, vol.140
, pp. 793-802
-
-
Narotam, P.K.1
Rodell, T.2
Nadvi, S.S.3
Bhoola, K.D.4
Troha, J.M.5
Parbhoosingh, R.6
Van Dellen, J.R.7
-
21
-
-
0030609160
-
4-induced liver cirrhosis: Possible role of enhanced microvascular leakage
-
4-induced liver cirrhosis: Possible role of enhanced microvascular leakage. Eur J Pharmacol 1997, 337: 45-53.
-
(1997)
Eur J Pharmacol
, vol.337
, pp. 45-53
-
-
Wirth, K.1
Bickel, M.2
Hropot, M.3
Gunzler, V.4
Heitsch, H.5
Ruppert, D.6
Scholkens, B.A.7
-
22
-
-
0008297261
-
Dimers of bradykinin and substance P antagonists as potential anti-cancer drugs
-
Stewart, J.M., Gera, L., Chan, D.C. Dimers of bradykinin and substance P antagonists as potential anti-cancer drugs. Pept Sci 1999, 1: 731-2.
-
(1999)
Pept Sci
, vol.1
, pp. 731-732
-
-
Stewart, J.M.1
Gera, L.2
Chan, D.C.3
-
23
-
-
33646233479
-
-
(Sanofi-Aventis). Use of bradykinin antagonists for the treatment of viral diseases. CA 2138933, EP 661058, JP 1995206703, US 5789383
-
Lembeck, F., Wirth, K., Winkler, I., Breipohl, G., Henkse, S., Knolle, J. (Sanofi-Aventis). Use of bradykinin antagonists for the treatment of viral diseases. CA 2138933, EP 661058, JP 1995206703, US 5789383.
-
-
-
Lembeck, F.1
Wirth, K.2
Winkler, I.3
Breipohl, G.4
Henkse, S.5
Knolle, J.6
-
24
-
-
33646260499
-
-
(Active Biotech AB.) Use of kinin antagonists for preparing a pharmaceutical composition for treating bacterial infections. US 6221845, WO 1997044353
-
Björck, L., Sjöbring, U., Ben Nasr, A., Olsen, A., Herwald, H., Muller-Esterl, W. (Active Biotech AB.) Use of kinin antagonists for preparing a pharmaceutical composition for treating bacterial infections. US 6221845, WO 1997044353.
-
-
-
Björck, L.1
Sjöbring, U.2
Ben Nasr, A.3
Olsen, A.4
Herwald, H.5
Muller-Esterl, W.6
-
25
-
-
0025969299
-
Hoe 140, a new potent and long acting bradykinin-antagonist: In vitro studies
-
Hock, F.J., Wirth, K., Albus, U. et al. Hoe 140, a new potent and long acting bradykinin-antagonist: In vitro studies. Br J Pharmacol 1991, 102: 769-73.
-
(1991)
Br J Pharmacol
, vol.102
, pp. 769-773
-
-
Hock, F.J.1
Wirth, K.2
Albus, U.3
-
26
-
-
0028234866
-
2 receptor antagonist, Hoe 140, in isolated blood vessels from different species
-
2 receptor antagonist, Hoe 140, in isolated blood vessels from different species. Br J Pharmacol 1994, 112: 683-9.
-
(1994)
Br J Pharmacol
, vol.112
, pp. 683-689
-
-
Félétou, M.1
Germain, M.2
Thurieau, C.3
Fauchère, J.-L.4
Canet, E.5
-
27
-
-
0028899603
-
In vitro effects of HOE 140 in human bronchial, and vascular tissue
-
Félétou, M., Martin, C.A.E., Molimard, M., Naline, E. Germain, M., Thurieau, C., Fauchère J.-L. Canet, E., Advenier, C. In vitro effects of HOE 140 in human bronchial, and vascular tissue. Eur J Pharmacol 1995, 274: 57-64
-
(1995)
Eur J Pharmacol
, vol.274
, pp. 57-64
-
-
Félétou, M.1
Martin, C.A.E.2
Molimard, M.3
Naline, E.4
Germain, M.5
Thurieau, C.6
Fauchère, J.-L.7
Canet, E.8
Advenier, C.9
-
29
-
-
0037615223
-
Implication of the bradykinin receptors in antigen-induced pulmonary inflammation in mice
-
Eric, J., Gabra, B.H., Sirois, P. Implication of the bradykinin receptors in antigen-induced pulmonary inflammation in mice. Br J Pharmacol 2003, 138: 1589-97.
-
(2003)
Br J Pharmacol
, vol.138
, pp. 1589-1597
-
-
Eric, J.1
Gabra, B.H.2
Sirois, P.3
-
30
-
-
0026534406
-
Effects of Hoe 140, a new bradykinin receptor antagonist on bradykinin- and platelet-activating factor-induced bronchoconstriction and airway microvascular leakage in guinea pig
-
Sakamoto, T., Elwood, W., Barnes, P.J., Chung, K.F. Effects of Hoe 140, a new bradykinin receptor antagonist on bradykinin- and platelet-activating factor-induced bronchoconstriction and airway microvascular leakage in guinea pig. Eur J Pharmacol 1992, 213: 367-73.
-
(1992)
Eur J Pharmacol
, vol.213
, pp. 367-373
-
-
Sakamoto, T.1
Elwood, W.2
Barnes, P.J.3
Chung, K.F.4
-
31
-
-
0032586030
-
2 antagonist HOE 140 inhibits late allergic microvascular leakage in guinea pig airways
-
2 antagonist HOE 140 inhibits late allergic microvascular leakage in guinea pig airways. Immunopharmacology 1999, 43: 249-53.
-
(1999)
Immunopharmacology
, vol.43
, pp. 249-253
-
-
Mashito, Y.1
Ichinose, M.2
Shirato, K.3
-
32
-
-
20244363204
-
Hoe 740, a new potent and long-acting bradykinin-antagonist: In vivo studies
-
Wirth, K., Hock, F.J., Albus, U. et al. Hoe 740, a new potent and long-acting bradykinin-antagonist: In vivo studies. Br J Pharmacol 1991, 102: 774-7.
-
(1991)
Br J Pharmacol
, vol.102
, pp. 774-777
-
-
Wirth, K.1
Hock, F.J.2
Albus, U.3
-
33
-
-
0029980742
-
Inhibition of rats adjuvant arthritis by a bradykinin antagonist Hoe 140 and its influence on kallikreins
-
Sharma, J.N., Wirth, K.J. Inhibition of rats adjuvant arthritis by a bradykinin antagonist Hoe 140 and its influence on kallikreins. Gen Pharmacol 1996, 27: 133-6.
-
(1996)
Gen Pharmacol
, vol.27
, pp. 133-136
-
-
Sharma, J.N.1
Wirth, K.J.2
-
34
-
-
0027318063
-
Inhibitory effects of Hoe 140 on vasodilator responses to bradykinin in the mesenteric vascular bed of the cat
-
Santiago, J.A., Osei, S.Y., Kadowitz, P.J. Inhibitory effects of Hoe 140 on vasodilator responses to bradykinin in the mesenteric vascular bed of the cat. Eur J Pharmacol 1993, 236: 315-8.
-
(1993)
Eur J Pharmacol
, vol.236
, pp. 315-318
-
-
Santiago, J.A.1
Osei, S.Y.2
Kadowitz, P.J.3
-
35
-
-
3242886755
-
Subcutaneous icatibant produces positive results in bioavailability study
-
April 16
-
Subcutaneous icatibant produces positive results in bioavailability study. DailyDrugNews.com (Daily Essentials) April 16, 2004.
-
(2004)
DailyDrugNews.com (Daily Essentials)
-
-
-
36
-
-
33646245022
-
Icatibant has no impact on renal function in healthy subjects
-
Abst P11-19
-
Rousso, P., Nguyen, M., Perrin, Y. et al. Icatibant has no impact on renal function in healthy subjects. Clin Pharmacol Ther 2004, 75(2): Abst P11-19.
-
(2004)
Clin Pharmacol Ther
, vol.75
, Issue.2
-
-
Rousso, P.1
Nguyen, M.2
Perrin, Y.3
-
37
-
-
3242880092
-
Pharmacokinetic and pharmacodynamic profile of icatibant
-
Abst P11-16
-
Perrin, Y., Nguyen, M. T., Rousso, P. et al. Pharmacokinetic and pharmacodynamic profile of icatibant. Clin Pharmacol Ther 2004, 75(2): Abst P11-16.
-
(2004)
Clin Pharmacol Ther
, vol.75
, Issue.2
-
-
Perrin, Y.1
Nguyen, M.T.2
Rousso, P.3
-
38
-
-
33645195433
-
2 receptor antagonist, improves natriuresis and diuresis after sodium challenge in patients with liver cirrhosis
-
Abst 1092
-
2 receptor antagonist, improves natriuresis and diuresis after sodium challenge in patients with liver cirrhosis. Hepatology 2004, 40(4. Suppl. 1): Abst 1092.
-
(2004)
Hepatology
, vol.40
, Issue.4 SUPPL. 1
-
-
Russmann, S.1
Buclin, T.2
Decosterd, L.3
Baumann, S.4
Brunner-Ferber, F.5
Rosenkranz, B.6
Knolle, J.7
Biollaz, J.8
Reichen, J.9
-
39
-
-
33645180349
-
Bradykinin-receptor-inhibition - A therapeutic option in osteoarthritis?
-
Abst P332
-
Flechtenmacher, J., Talke, M., Veith, D., Heil, K., Gebauer, A., Schoenharting, M. Bradykinin-receptor-inhibition - A therapeutic option in osteoarthritis? Osteoarthritis Cartilage 2004, 12(Suppl. B): Abst P332.
-
(2004)
Osteoarthritis Cartilage
, vol.12
, Issue.SUPPL. B
-
-
Flechtenmacher, J.1
Talke, M.2
Veith, D.3
Heil, K.4
Gebauer, A.5
Schoenharting, M.6
-
40
-
-
0030175506
-
Efficacy and tolerability of icatibant (Hoe 140) in patients with moderately severe chronic bronchial asthma
-
Akbary, A.M., Wirth, K.J., Schölkens, B.A. Efficacy and tolerability of icatibant (Hoe 140) in patients with moderately severe chronic bronchial asthma. Immunopharmacology 1996, 238: 238-42.
-
(1996)
Immunopharmacology
, vol.238
, pp. 238-242
-
-
Akbary, A.M.1
Wirth, K.J.2
Schölkens, B.A.3
-
43
-
-
33646250230
-
Kos and Jerini sign agreement for icatibant in U.S. and Canada
-
November 9
-
Kos and Jerini sign agreement for icatibant in U.S. and Canada. DailyDrugNews.com (Daily Essentials) November 9. 2005.
-
(2005)
DailyDrugNews.com (Daily Essentials)
-
-
|