The bradykinin B, receptor antagonist Icatibant (HOE 140) corrects avid Na+ retention in rats with CCl4-induced liver cirrhosis: Possible role of enhanced microvascular leakage

European Journal of Pharmacology

Volumn 337, Issue 1, 1997, Pages 45-53

  Wirth, Klaus J ^a   Bickel, Martin ^a   Hropot, Max ^a   Günzler, Volkmar ^a   Heitsch, Holger ^a   Ruppert, Dieter ^a   Schölkens, Bernward A ^a  

^a SANOFI   (France)

Author keywords

Bradykinin B2 receptor antagonist; CCl4 induced liver cirrhosis; Hepatorenal syndrome; HOE 140; Micorvascular leakage; Na+ retention

Indexed keywords

BRADYKININ; BRADYKININ ANTAGONIST; ICATIBANT; BRADYKININ RECEPTOR; CREATININE; DRUG DERIVATIVE; SODIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EXPERIMENTAL LIVER CIRRHOSIS; HEPATORENAL SYNDROME; HYPERACTIVITY; NONHUMAN; PRIORITY JOURNAL; RAT; VASCULAR DISEASE; VASODILATATION; ANIMAL; BLOOD; BLOOD PRESSURE; BODY WEIGHT; CAPILLARY PERMEABILITY; CHEMICALLY INDUCED DISORDER; DIURESIS; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; INTOXICATION; KIDNEY FUNCTION TEST; MALE; METABOLISM; ORGAN SIZE; PATHOLOGY; WISTAR RAT;

ANIMALS; BLOOD PRESSURE; BODY WEIGHT; BRADYKININ; CAPILLARY PERMEABILITY; CARBON TETRACHLORIDE POISONING; CREATININE; DIURESIS; FEMALE; KIDNEY FUNCTION TESTS; LIVER CIRRHOSIS, EXPERIMENTAL; MALE; ORGAN SIZE; RATS; RATS, WISTAR; RECEPTORS, BRADYKININ; SODIUM;

EID: 0030609160     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01281-8     Document Type: Article

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