Excess methionine suppresses the methylation cycle and inhibits neural tube closure in mouse embryos

FEBS Letters

Volumn 580, Issue 11, 2006, Pages 2803-2807

  Dunlevy, Louisa P E ^a   Burren, Katie A ^a   Chitty, Lyn S ^a   Copp, Andrew J ^a   Greene, Nicholas D E ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Exencephaly; Methionine; Neural tube defect; S Adenosylhomocysteine; S Adenosylmethionine

Indexed keywords

ADENOSYLHOMOCYSTEINASE; DNA; FOLIC ACID; METHIONINE; S ADENOSYLMETHIONINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CELL DENSITY; CELL PROLIFERATION; CONTROLLED STUDY; DNA METHYLATION; EMBRYO; EMBRYO CULTURE; FREQUENCY ANALYSIS; GENE REPRESSION; MESENCHYME; MOUSE; NEURAL TUBE DEFECT; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; AZACITIDINE; EMBRYO; EMBRYO CULTURE TECHNIQUES; FOLIC ACID; METHIONINE; METHYLATION; MICE; NEURAL TUBE DEFECTS; PHENOTYPE;

ANIMALIA;

EID: 33646196192     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.04.020     Document Type: Article

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