Canonical organization of opioid modulation of nociceptive circuits. Focus on "μ opioid receptor activation inhibits GABAergic inputs to basolateral amygdala neurons through Kv1.1/Kv1.2 channels"

Journal of Neurophysiology

Volumn 95, Issue 4, 2006, Pages 2029-2030

  Sah, Pankaj ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; MU OPIATE RECEPTOR; POTASSIUM CHANNEL KV1.1; POTASSIUM CHANNEL KV1.2; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

AMYGDALOID NUCLEUS; ANTINOCICEPTION; CANONICAL ANALYSIS; EDITORIAL; NERVE CELL; NOCICEPTION; PRIORITY JOURNAL;

AMYGDALA; ANIMALS; GAMMA-AMINOBUTYRIC ACID; KV1.1 POTASSIUM CHANNEL; KV1.2 POTASSIUM CHANNEL; LIMBIC SYSTEM; MALE; NEURONS, AFFERENT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID; RECEPTORS, OPIOID, MU;

EID: 33646182414     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.01259.2005     Document Type: Editorial

References (16)

1. Faber ES and Sah P. Opioids inhibit lateral amygdala pyramidal neurons by enhancing a dendritic potassium current. J Neurosci 24: 3031-3039, 2004.
2. Fields H. State-dependent opioid control of pain. Nat Rev Neurosci 5: 565-575, 2004.
3. Finnegan TF, Chen S-R, and Pan H-L. μ opioid receptor activation inhibits GABAergic inputs to basolateral amygdala neurons through Kv1.1/Kv1.2 channels. J Neurophysiol 95: 2032-2041, 2006.
4. Finnegan TF, Chen SR, and Pan HL. Effect of the μ opioid on excitatory and inhibitory synaptic inputs to periaqueductal gray-projecting neurons in the amygdala. J Pharmacol Exp Ther 312: 441-448, 2005.
5. Finnegan TF, Li DP, Chen SR, and Pan HL. Activation of mu-opioid receptors inhibits synaptic inputs to spinally projecting rostral ventromedial medulla neurons. J Pharmacol Exp Ther 309: 476-483, 2004.
6. Harris JA. Descending antinociceptive mechanisms in the brainstem: their role in the animal's defensive system. J Physiol 90: 15-25, 1996.
7. Heinricher MM, Morgan MM, Tortorici V, and Fields HL. Disinhibition of off-cells and antinociception produced by an opioid action within the rostral ventromedial medulla. Neuroscience 63: 279-288, 1994.
8. Hopkins DA and Holstege G. Amygdaloid projections to the mesencephalon pons and medulla oblongata in the cat. Exp Brain Res 32: 529-547, 1978.
9. LeDoux J. The emotional brain, fear, and the amygdala. Cell Mol Neurobiol 23: 727-738, 2003.
10. Millan MJ. Descending control of pain. Prog Neurobiol 66: 355-474, 2002.
11. Price DD. Psychological Mechanisms of Pain and Analgesia. Seattle: ASP Press, 1999.
12. Rizvi TA, Ennis M, Behbehani MM, and Shipley MT. Connections between the central nucleus of the amygdala and the midbrain periaqueductal gray: topography and reciprocity. J Comp Neurol 303: 121-131, 1991.
13. Sah P, Faber ES, Lopez De Armentia M, and Power J. The amygdaloid complex: anatomy and physiology. Physiol Rev 83: 803-834, 2003.
14. Shin MS and Helmstetter FJ. Antinociception following application of DAMGO to the basolateral amygdala results from a direct interaction of DAMGO with Mu opioid receptors in the amygdala. Brain Res, 2005.
15. Vaughan CW, Ingram SL, Connor MA, and Christie MJ. How opioids inhibit GABA-mediated neurotransmission. Nature 390: 611-614, 1997.
16. Williams JT, Christie MJ, and Manzoni O. Cellular and synaptic adaptations mediating opioid dependence. Physiol Rev 81: 299-343, 2001.