Chlamydia pneumoniae infection enhances cellular proliferation and reduces steroid responsiveness of human peripheral blood mononuclear cells via a tumor necrosis factor-α-dependent pathway

Clinical and Experimental Allergy

Volumn 35, Issue 12, 2005, Pages 1625-1631

  Cho, Y S ^a   Kim, T B ^a   Lee, T H ^a   Moon, K A ^a   Lee, J ^a   Kim, Y K ^b   Lee, K Y ^a   Moon, H B ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

Author keywords

Chlamydia pneumoniae; Corticosteroid; Peripheral blood mononuclear cell; TNF

Indexed keywords

CORTICOSTEROID; DEXAMETHASONE; INFLIXIMAB; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

APOPTOSIS; ARTICLE; ASTHMA; ATOPY; CELL PROLIFERATION; CELL SURVIVAL; CHLAMYDIASIS; CHLAMYDOPHILA PNEUMONIAE; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA SYNTHESIS; DRUG SENSITIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; INFLAMMATORY CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; TH2 CELL; BACTERIAL INFECTION; CELL CULTURE; HYPERSENSITIVITY; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MONONUCLEAR CELL; NONPARAMETRIC TEST; PATHOLOGY; SIGNAL TRANSDUCTION;

ADRENAL CORTEX HORMONES; ANTIBODIES, MONOCLONAL; APOPTOSIS; CELL PROLIFERATION; CELLS, CULTURED; CHLAMYDOPHILA INFECTIONS; CHLAMYDOPHILA PNEUMONIAE; DEXAMETHASONE; HUMANS; HYPERSENSITIVITY; LEUKOCYTES, MONONUCLEAR; RECEPTORS, TUMOR NECROSIS FACTOR; SIGNAL TRANSDUCTION; STATISTICS, NONPARAMETRIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33646174359     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2005.02391.x     Document Type: Article

References (22)

1. Grayston JT Campbell LA Kuo CC et al. A new respiratory tract pathogen: Chlamydia pneumoniae strain TWAR. J Infect Dis 1990 161 : 618 25.
2. Von HL Vasankari T Liippo K Wahlstrom E Puolakkainen M. Chlamydia pneumoniae and severity of asthma. Scand J Infect Dis 2002 34 : 22 7.
3. Hahn DL Bukstein D Luskin A Zeitz H. Evidence for Chlamydia pneumoniae infection in steroid-dependent asthma. Ann Allergy Asthma Immunol 1998 80 : 45 9.
4. Black PN Scicchitano R Jenkins CR et al. Serological evidence of infection with Chlamydia pneumoniae is related to the severity of asthma. Eur Respir J 2000 15 : 254 9.
5. ten Brinke A van Dissel JT Sterk PJ Zwinderman AH Rabe KF Bel EH. Persistent airflow limitation in adult-onset nonatopic asthma is associated with serologic evidence of Chlamydia pneumoniae infection. J Allergy Clin Immunol 2001 107 : 449 54.
6. Miyashita N Kubota Y Nakajima M Niki Y Kawane H Matsushima T. Chlamydia pneumoniae and exacerbations of asthma in adults. Ann Allergy Asthma Immunol 1998 80 : 405 9.
7. Hahn DL McDonald R. Can acute Chlamydia pneumoniae respiratory tract infection initiate chronic asthma? Ann Allergy Asthma Immunol 1998 81 : 339 44.
8. Esposito S Blasi F Arosio C et al. Importance of acute Mycoplasma pneumoniae and Chlamydia pneumoniae infections in children with wheezing. Eur Respir J 2000 16 : 1142 6.
9. Kutlin A Roblin PM Hammerschlag MR. Effect of prolonged treatment with azithromycin, clarithromycin, or levofloxacin on Chlamydia pneumoniae in a continuous-infection model. Antimicrob Agents Chemotherapy 2002 46 : 409 12.
10. Rodel J Woytas M Groh A et al. Production of basic fibroblast growth factor and interleukin 6 by human smooth muscle cells following infection with Chlamydia pneumoniae. Infection and Immunity 2000 68 : 3635 41.
11. Kaukoranta-Tolvanen SS Teppo AM Laitinen K Saikku P Linnavuori K Leinonen M. Growth of Chlamydia pneumoniae in cultured human peripheral blood mononuclear cells and induction of a cytokine response. Microb Pathogen 1996 21 : 215 1.
12. Carratelli CR Rizzo A Catania MR et al. Chlamydia pneumoniae infections prevent the programmed cell death on THP-1 cell. FEMS Microbiol Lett 2002 215 : 69 74.
13. Airenne S Surcel HM Tuukkanen J Leinonen M Saikku P. Chlamydia pneumoniae inhibits apoptosis in human epithelial and monocyte cell lines. Scand J Immunol 2002 55 : 390 8.
14. Rajalingam K Al-Younes H Muller A Meyer TF Szczepek AJ Rudel T. Epithelial cells infected with Chlamydophila pneumoniae (Chlamydia pneumoniae) are resistant to apoptosis. Infect Immun 2001 69 : 7880 8.
15. Redecke V Dalhoff K Bohnet S Braun J Maass M. Interaction of Chlamydia pneumoniae and human alveolar macrophages: infection and inflammatory response. Am J Respir Cell Mol Biol 1998 19 : 721 7.
16. Caspar-Bauguil S Puissant B Nazzal D et al. Chlamydia pneumoniae induces interleukin-10 production that down-regulates major histocompatibility complex class I expression. J Infect Dis 2000 182 : 1394 401.
17. Ohta K Yamashita N. Apoptosis of eosinophils and lymphocytes in allergic inflammation. J Allergy Clin Immunol 1999 104 : 14 21.
18. Feldmann M Brennan FM Maini RN. Role of cytokines in rheumatoid arthritis. Ann Rev Immunol 1996 14 : 397 440.
19. von HL. Role of persistent infection in the control and severity of asthma: focus on Chlamydia pneumoniae. Eur Respir J 2002 19 : 546 6.
20. Airenne S Surcel HM Bloigu A Laitinen K Saikku P Laurila A. The resistance of human monocyte-derived macrophages to Chlamydia pneumoniae infection is enhanced by interferon-gamma. APMIS 2000 108 : 139 44.
21. Mitoma H Horiuchi T Hatta N et al. Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-alpha. Gastroenterology 2005 128 : 376 92.
22. van den Branda J Hommes DW Peppelenbosch MP. Infliximab induced T lymphocyte apoptosis in Crohn's disease. J Rheumatol 2005 74 (Suppl.) : 26 30.