Insights into the processes behind the contamination of degraded human teeth and bone samples with exogenous sources of DNA

International Journal of Osteoarchaeology

Volumn 16, Issue 2, 2006, Pages 156-164

  Gilbert, M T P ^a,b   Hansen, A J ^c   Willerslev, E ^a,c   Turner Walker, G ^d,e   Collins, M ^f  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b University of Arizona   (United States)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^e NATIONAL YUNLIN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^f UNIVERSITY OF YORK   (United Kingdom)

Author keywords

Ancient DNA; Bone; Contamination; Human; Tooth

Indexed keywords

EID: 33646167599     PISSN: 1047482X     EISSN: 10991212     Source Type: Journal    
DOI: 10.1002/oa.832     Document Type: Article

References (20)

1. Allen M, Engström A-S, Meyer S, Handt O, Saldeen T, von Haeseler A, Pääbo S, Gyllensten U. 1998. Mitochondrial DNA sequencing of shed hairs and saliva on robbery caps: sensitivity and matching probabilities. Journal of Forensic Science 43: 453-464.
2. Barnes I, Matheus P, Shapiro B, Jensen D, Cooper A. 2002. Dynamics of mammal population extinctions in Eastern Beringia during the last glaciation. Science 295: 2267-2270.
3. Cooper A, Poinar H. 2000. Ancient DNA: do it right or not at all. Science 289: 1139.
4. Currey J. 2002. Bones: Structure and Mechanics. Princeton University Press: Princeton.
5. Drancourt M, Aboudharam G, Signoli M, Dutour O, Raoult D. 1998. Detection of 400-year-old Yersinia pestis DNA in human dental pulp: an approach to the diagnosis of ancient septicemia. Proceedings of the National Academy of Sciences of the USA 95: 12637-12640.
6. Gilbert MTP, Willerslev E, Hansen AJ, Rudbeck L, Barnes I, Lynnerup N, Cooper A. 2003. Distribution patterns of post mortem damage in human mitochondrial DNA. American Journal of Human Genetics 72: 32-47.
7. Gilbert MTP, Rudbeck L, Willerslev E, Hansen AJ, Smith C, Penkman KEH, Prangenberg K, Nielsen-Marsh CM, Jans ME, Arthur P, Lynnerup N, Turner-Walker G, Biddle M, Kjølbye-Biddle B, Collins M. 2005. Biochemical and physical correlates of DNA contamination in archaeological human bones and teeth excavated at Matera, Italy. Journal of Archaeological Science 32: 1053-1060.
8. González-Olivier A, Márquez-Morfin L, Jiminéz JC, Torre-Blanco A. 2001. Founding amerindian mitochondrial DNA lineages in ancient Maya from Xcaret, Quintana Roo. American Journal of Physical Anthropology 116: 230-235.
9. Handt O, Krings M, Ward R, Pääbo S. 1996. The retrieval of ancient human DNA sequences. American Journal of Human Genetics 59: 368-376.
10. Hedges REM. 2002. Bone diagenesis: an overview of processes. Archaeometry 44: 319-328.
11. Hofreiter M, Serre D, Poinar HN, Kuch M, Pääbo S. 2001. Ancient DNA. Nature Reviews Genetics 2: 353-358.
12. Kolman CJ, Tuross N. 2000. Ancient DNA analysis of human populations. American Journal of Physical Anthropology 111: 5-23.
13. Leonard JA, Wayne RK, Cooper A. 2000. Population genetics of Ice Age brown bears. Proceedings of the National Academy of Sciences of the USA 97:1651-1654.
14. Malmström H, Stora J, Dalen L, Holmlund G, Götherström A. 2005. Extensive human DNA contamination in extracts from ancient dog bones and teeth. Molecular Biology and Evolution, in press.
15. Metspalu M, Kivisild T, Metspalu E, Parik J, Hudjashov G, Kaldma K, Serk P, Karmin M, Behar DM, Gilbert MTP, Endicott P, Mastana S, Papiha SS, Skorecki K, Torroni A, Villems R. 2004. Most of the extant mtDNA boundaries in South and Southwest Asia were likely shaped during the initial settlement of Eurasia by anatomically modern humans. BMC Genetics 5: 26.
16. Oota H, Saitou N, Matsushita T, Ueda S. 1995. A genetic study of 2000 year old human remains from Japan using mitochondrial DNA sequences. American Journal of Physical Anthropology 98: 133-145.
17. Richards M, Sykes B, Hedges R. 1995. Authenticating DNA extracted from ancient skeletal remains. Journal of Archaeological Science 22: 291-299.
18. Richards M, Macaulay V, Hickey E, Vega E, Sykes B, Guida V, Rengo C, Sellitto D, Cruciani F, Kivisild T, Villems R, Thomas M, Rychkov S, Rychkov O, Rychkov Y, Gölge M, Dimitrov D, Hill E, Bradley D, Romano V, Calz̀ F, Vona G, Demaine A, Papiha S, Triantaphyllidis C, Stefanescu G, Hatina J, Belledi M, Di Rienzo A, Novelletto A, Oppenheim O, Nørby S, Santachiara - Benerecetti S, Scozzari R, Torroni A, Bandelt H-J. 2000. Tracing European founder lineages in the Near Eastern mtDNA pool. American Journal of Human Genetics 67: 1251-1276.
19. Turner-Walker G, Nielsen-Marsh CM, Syversen U, Kars H, Collins MJ. 2002. Sub-micron spongiform porosity is the major ultra-structural alteration occurring in archaeological bone. International Journal of Osteoarcheology 12: 407-414.
20. Wandeler P, Smith S, Morin PA, Pettifor RA, Funk SM. 2003. Patterns of nuclear DNA degeneration over time - a case study in historic teeth samples. Molecular Ecology 12: 1087-1093.