메뉴 건너뛰기




Volumn 6, Issue 1-2, 2006, Pages 117-122

Inactivity of recombinant ELA2B provides a new example of evolutionary elastase silencing in humans

Author keywords

Antitrypsin; Gene duplication; Pancreatic elastase; Pseudogene

Indexed keywords

ALPHA 1 ANTITRYPSIN; ANILIDE; BOVINE MILK PROTEIN; CHIMERIC PROTEIN; DODECYL SULFATE SODIUM; DQ ELASTIN; ELASTASE; ELASTASE 2A; ELASTASE 2B; ELASTIN; GLUTAMYLALANYLALANYLPROLYLLEUCYL 4 NITROANILIDE; MILK PROTEIN; PANCREATIC ELASTASE; RECOMBINANT ELASTASE 2A; RECOMBINANT ELASTASE 2B; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

EID: 33646153277     PISSN: 14243903     EISSN: 14243911     Source Type: Journal    
DOI: 10.1159/000090031     Document Type: Article
Times cited : (19)

References (15)
  • 1
    • 0023109108 scopus 로고
    • Characterization of a silent gene for human pancreatic elastase I: Structure of the 5′-flanking region
    • Tokyo
    • Tani T, Kawashima I, Furukawa H, Ohmine T, Takiguchi Y: Characterization of a silent gene for human pancreatic elastase I: structure of the 5′-flanking region. J Biochem (Tokyo) 1987;101:591-599.
    • (1987) J Biochem , vol.101 , pp. 591-599
    • Tani, T.1    Kawashima, I.2    Furukawa, H.3    Ohmine, T.4    Takiguchi, Y.5
  • 3
    • 0030927748 scopus 로고    scopus 로고
    • Evolutionary silencing of the human elastase I gene (ELA1)
    • Rose SD, MacDonald RJ: Evolutionary silencing of the human elastase I gene (ELA1). Hum Mol Genet 1997;6:897-903.
    • (1997) Hum Mol Genet , vol.6 , pp. 897-903
    • Rose, S.D.1    MacDonald, R.J.2
  • 4
    • 0034045031 scopus 로고    scopus 로고
    • Human elastase 1: Evidence for expression in the skin and the identification of a frequent frameshift polymorphism
    • Talas U, Dunlop J, Khalaf S, Leigh IM, Kelsell DP: Human elastase 1: evidence for expression in the skin and the identification of a frequent frameshift polymorphism. J Invest Dermatol 2000;114:165-170.
    • (2000) J Invest Dermatol , vol.114 , pp. 165-170
    • Talas, U.1    Dunlop, J.2    Khalaf, S.3    Leigh, I.M.4    Kelsell, D.P.5
  • 5
    • 0017174488 scopus 로고
    • Purification and characterization of two human pancreatic elastases
    • Largman C, Brodrick JW, Geokas MC: Purification and characterization of two human pancreatic elastases. Biochemistry 1976;15:2491-2500.
    • (1976) Biochemistry , vol.15 , pp. 2491-2500
    • Largman, C.1    Brodrick, J.W.2    Geokas, M.C.3
  • 6
    • 0017115114 scopus 로고
    • Purification and partial characterization of human pancreatic elastase
    • Ohlsson K, Olsson A-S: Purification and partial characterization of human pancreatic elastase. Hoppe Seyler's Z Physiol Chem 1976;357:81153-1161.
    • (1976) Hoppe Seyler's Z Physiol Chem , vol.357 , pp. 81153-81161
    • Ohlsson, K.1    Olsson, A.-S.2
  • 7
    • 0023105553 scopus 로고
    • Characterization of pancreatic elastase II cDNAs: Two elastase II mRNAs are expressed in human pancreas
    • Kawashima I, Tani T, Shimoda K, Takiguchi Y: Characterization of pancreatic elastase II cDNAs: two elastase II mRNAs are expressed in human pancreas. DNA 1987;6:163-172.
    • (1987) DNA , vol.6 , pp. 163-172
    • Kawashima, I.1    Tani, T.2    Shimoda, K.3    Takiguchi, Y.4
  • 9
    • 0023502002 scopus 로고
    • Primary structure of human pancreatic elastase 2 determined by sequence analysis of the cloned mRNA
    • Fletcher TS, Shen WF, Largman C: Primary structure of human pancreatic elastase 2 determined by sequence analysis of the cloned mRNA. Biochemistry 1987;26:7256-7261.
    • (1987) Biochemistry , vol.26 , pp. 7256-7261
    • Fletcher, T.S.1    Shen, W.F.2    Largman, C.3
  • 10
    • 0034725697 scopus 로고    scopus 로고
    • Human cationic trypsinogen: Role of Asn-21 in zymogen activation and implications in hereditary pancreatitis
    • Sahin-Tóth M: Human cationic trypsinogen: role of Asn-21 in zymogen activation and implications in hereditary pancreatitis. J Biol Chem 2000;275:22750-22755.
    • (2000) J Biol Chem , vol.275 , pp. 22750-22755
    • Sahin-Tóth, M.1
  • 11
    • 0034687560 scopus 로고    scopus 로고
    • Gain-of-function mutations associated with hereditary pancreatitis enhance autoactivation of human cationic trypsinogen
    • Sahin-Tóth M, Tóth M: Gain-of-function mutations associated with hereditary pancreatitis enhance autoactivation of human cationic trypsinogen. Biochem Biophys Res Commun 2000;278:286-289.
    • (2000) Biochem Biophys Res Commun , vol.278 , pp. 286-289
    • Sahin-Tóth, M.1    Tóth, M.2
  • 12
    • 0038029879 scopus 로고    scopus 로고
    • Human anionic trypsinogen. Properties of autocatalytic activation and degradation and implications in pancreatic diseases
    • Kukor Z, Tóth M, Sahin-Tóth M: Human anionic trypsinogen. Properties of autocatalytic activation and degradation and implications in pancreatic diseases. Eur J Biochem 2003;270:2047-2058.
    • (2003) Eur J Biochem , vol.270 , pp. 2047-2058
    • Kukor, Z.1    Tóth, M.2    Sahin-Tóth, M.3
  • 14
    • 0029863066 scopus 로고    scopus 로고
    • Hydrophobic interactions control zymogen activation in the trypsin family of serine proteases
    • Hedstrom L, Lin TY, Fast W: Hydrophobic interactions control zymogen activation in the trypsin family of serine proteases. Biochemistry 1996;35:4515-4523.
    • (1996) Biochemistry , vol.35 , pp. 4515-4523
    • Hedstrom, L.1    Lin, T.Y.2    Fast, W.3
  • 15
    • 1342326179 scopus 로고    scopus 로고
    • Two-dimensional protein database of human pancreas
    • Hu L, Evers S, Lu ZH, Shen Y, Chen J: Two-dimensional protein database of human pancreas. Electrophoresis 2004;25:512-518.
    • (2004) Electrophoresis , vol.25 , pp. 512-518
    • Hu, L.1    Evers, S.2    Lu, Z.H.3    Shen, Y.4    Chen, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.