Altered cerebellar function in mice lacking CaV2.3 Ca2+ channel

Biochemical and Biophysical Research Communications

Volumn 344, Issue 3, 2006, Pages 920-925

  Osanai, Makoto ^a   Saegusa, Hironao ^a   Kazuno, An a ^a   Nagayama, Shin ^a   Hu, Qiuping ^a   Zong, Shuqin ^a   Murakoshi, Takayuki ^a   Tanabe, Tsutomu ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

CaV2.3 channel; Discharge property; Knock out mouse; Long term depression; R type Ca2+ channel; Rotarod; Voltage dependent Ca2+ channel

Indexed keywords

VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN FUNCTION; CEREBELLUM CORTEX; CEREBELLUM DISEASE; CONTROLLED STUDY; GENE DISRUPTION; GENE DOSAGE; GENE EXPRESSION; HETEROZYGOSITY; HOMOZYGOSITY; LONG TERM DEPRESSION; MOTOR COORDINATION; MOTOR PERFORMANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; ROTAROD TEST; SPECIES COMPARISON; VOLTAGE CLAMP;

ACTION POTENTIALS; ANIMALS; CALCIUM CHANNELS; CALCIUM CHANNELS, R-TYPE; CATION TRANSPORT PROTEINS; CELLS, CULTURED; CEREBELLUM; ION CHANNEL GATING; LONG-TERM DEPRESSION (PHYSIOLOGY); MICE; MICE, KNOCKOUT; PURKINJE CELLS; ROTAROD PERFORMANCE TEST;

ANIMALIA;

EID: 33646150216     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.03.206     Document Type: Article

References (29)

1. Ito M. Cerebellar long-term depression: characterization, signal transduction, and functional roles. Physiol. Rev. 81 (2001) 1143-1195
2. Konnerth A., Dreessen J., and Augustine G.J. Brief dendritic calcium signals initiate long-lasting synaptic depression in cerebellar Purkinje cells. Proc. Natl. Acad. Sci. USA 89 (1992) 7051-7055
3. Ertel E.A., Campbel K.P., Harpold M.M., Hofmann F., Mori Y., Perez-Reyes E., Schwartz A., Snutch T.P., Tanabe T., Birnbaumer L., Tsien R.W., and Catterall W.A. Nomenclature of voltage-gated calcium channels. Neuron 25 (2000) 533-535
4. Fletcher C.F., Lutz C.M., O'Sullivan T.N., Shaughnessy J.D., Hawkes R., Frankel W.N., Copeland N.G., and Jenkins N.A. Absence epilepsy in tottering mutant mice is associated with calcium channel defects. Cell 87 (1996) 607-617
5. Jun K., Piedras-Renteria E.S., Smith S.M., Wheeler D.B., Lee S.B., Lee T.G., Chin H., Adams M.E., Scheller R.H., Tsien R.W., and Shin H.S. Ablation of P/Q-type Ca(2+) channel currents, altered synaptic transmission, and progressive ataxia in mice lacking the alpha(1A)-subunit. Proc. Natl. Acad. Sci. USA 96 (1999) 15245-15250
6. 2+ channels is associated with the ataxic mouse mutation rolling Nagoya (tg(rol)). J. Neurosci. 20 (2000) 5654-5662
7. Kaneda M., Wakamori M., Ito C., and Akaike N. Low-threshold calcium current in isolated Purkinje cell bodies of rat cerebellum. J. Neurophysiol. 63 (1990) 1046-1051
8. Regan L.J. Voltage-dependent calcium currents in Purkinje cells from rat cerebellar vermis. J. Neurosci. 11 (1991) 2259-2269
9. 2+ currents in dendritic recordings from Purkinje cells in rat cerebellar slice cultures. J. Neurosci. 17 (1997) 160-170
10. Pouille F., Cavelier P., Desplantez T., Beekenkamp H., Craig P.J., Beattie R.E., Volsen S.G., and Bossu J.L. Dendro-somatic distribution of calcium-mediated electrogenesis in purkinje cells from rat cerebellar slice cultures. J. Physiol. 527 (2000) 265-282
11. 2+ spike firing in the dendrites of cerebellar Purkinje neurons: a modeling study. Brain Res. 891 (2001) 106-115
12. Bourinet E., Zamponi G.W., Stea A., Soong T.W., Lewis B.A., Jones L.P., Yue D.T., and Snutch T.P. The alpha 1E calcium channel exhibits permeation properties similar to low-voltage-activated calcium channels. J. Neurosci. 16 (1996) 4983-4993
13. Wilson S.M., Toth P.T., Oh S.B., Gillard S.E., Volsen S., Ren D., Philipson L.H., Lee E.C., Fletcher C.F., Tessarollo L., Copeland N.G., Jenkins N.A., and Miller R.J. The status of voltage-dependent calcium channels in alpha 1E knock-out mice. J. Neurosci. 20 (2000) 8566-8571
14. Lee S.C., Choi S., Lee T., Kim H.L., Chin H., and Shin H.S. Molecular basis of R-type calcium channels in central amygdala neurons of the mouse. Proc. Natl. Acad. Sci. USA 99 (2002) 3276-3281
15. 2+ currents in murine hippocampal and neocortical neurons. J. Physiol. 542 (2002) 699-710
16. 2+ channel. Proc. Natl. Acad. Sci. USA 97 (2000) 6132-6137
17. V2.3 (alphaIE) channel. Biochem. Biophys. Res. Commun. 282 (2001) 242-248
18. 2+ channel in ischemic neuronal injury. Neuroreport 13 (2002) 261-265
19. 2+ channel. Anesth. Analg. 97 (2003) 96-103
20. Minabe-Saegusa C., Saegusa H., Tsukahara M., and Noguchi S. Sequence and expression of a novel mouse gene PRDC (protein related to DAN and cerberus) identified by a gene trap approach. Dev. Growth Differ. 40 (1998) 343-353
21. Pekhletski R., Gerlai R., Overstreet L.S., Huang X.P., Agopyan N., Slater N.T., Abramow-Newerly W., Roder J.C., and Hampson D.R. Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor. J. Neurosci. 16 (1996) 6364-6373
22. Augustin I., Korte S., Rickmann M., Kretzschmar H.A., Sudhof T.C., Herms J.W., and Brose N. The cerebellum-specific Munc13 isoform Munc13-3 regulates cerebellar synaptic transmission and motor learning in mice. J. Neurosci. 21 (2001) 10-17
23. Matsukawa H., Wolf A.M., Matsushita S., Joho R.H., and Knopfel T. Motor dysfunction and altered synaptic transmission at the parallel fiber-Purkinje cell synapse in mice lacking potassium channels Kv3.1 and Kv3.3. J. Neurosci. 23 (2003) 7677-7684
24. Doroshenko P.A., Woppmann A., Miljanich G., and Augustine G.J. Pharmacologically distinct presynaptic calcium channels in cerebellar excitatory and inhibitory synapses. Neuropharmacology 36 (1997) 865-872
25. Stephens G.J., Morris N.P., Fyffe R.E., and Robertson B. The Cav2.1/alpha1A (P/Q-type) voltage-dependent calcium channel mediates inhibitory neurotransmission onto mouse cerebellar Purkinje cells. Eur. J. Neurosci. 13 (2001) 1902-1912
26. Gilbert P.F., and Thach W.T. Purkinje cell activity during motor learning. Brain Res. 128 (1977) 309-328
27. Raymond J.L., and Lisberger S.G. Neural learning rules for the vestibulo-ocular reflex. J. Neurosci. 18 (1998) 9112-9129
28. 2+ channels in the dendrites of rat cerebellar Purkinje neurons. Brain Res. 791 (1998) 43-55
29. Suzuki T., Delgado-Escueta A.V., Aguan K., Alonso M.E., Shi J., Hara Y., Nishida M., Numata T., Medina M.T., Takeuchi T., Morita R., Bai D., Ganesh S., Sugimoto Y., Inazawa J., Bailey J.N., Ochoa A., Jara-Prado A., Rasmussen A., Ramos-Peek J., Cordova S., Rubio-Donnadieu F., Inoue Y., Osawa M., Kaneko S., Oguni H., Mori Y., and Yamakawa K. Mutations in EFHC1 cause juvenile myoclonic epilepsy. Nat. Genet. 36 (2004) 842-849