Improvement of contractility accompanies angiogenesis rather than arteriogenesis in chronic myocardial ischemia

Vascular Pharmacology

Volumn 44, Issue 5, 2006, Pages 326-332

  Heilmann, Claudia ^a   Kostic, Caterina ^a   Giannone, Bodo ^a   Grawitz, Andrea Busse ^a   Armbruster, Werner ^a   Lutter, Georg ^a   Beyersdorf, Friedhelm ^a   Göbel, Heike ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Gene therapy; Growth factors; Indirect revascularisation; Myocardial contractility; Myocardial ischemia

Indexed keywords

BIOLOGICAL MARKER; DNA; FIBROBLAST GROWTH FACTOR 2; GROWTH FACTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; PLASMID DNA;

ANGIOCARDIOGRAPHY; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY; CONTROLLED STUDY; CORONARY ARTERY OBSTRUCTION; CORRELATION ANALYSIS; DISEASE SEVERITY; DRUG POTENTIATION; ECHOCARDIOGRAPHY; GENE THERAPY; HEART EJECTION FRACTION; HEART MUSCLE CONTRACTILITY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REVASCULARIZATION; NONHUMAN; PRIORITY JOURNAL; SWINE;

ANIMALS; CAPILLARIES; CHEMOKINE CCL2; CHRONIC DISEASE; CORONARY STENOSIS; CORONARY VESSELS; DISEASE MODELS, ANIMAL; FIBROBLAST GROWTH FACTOR 2; GENE THERAPY; GENETIC VECTORS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MYOCARDIAL CONTRACTION; MYOCARDIAL ISCHEMIA; MYOCARDIUM; NEOVASCULARIZATION, PHYSIOLOGIC; SWINE;

EID: 33646144661     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vph.2006.01.002     Document Type: Article

References (28)

1. Buschmann I.R., et al. GM-CSF: a strong arteriogenic factor acting by amplification of monocyte function. Atherosclerosis 159 2 (2001) 343-356
2. Carmeliet P. Angiogenesis in health and disease. Nat. Med. 9 6 (2003) 653-660
3. Cason B.A., et al. Effects of high arterial oxygen tension on function, blood flow distribution, and metabolism in ischemic myocardium. Circulation 85 2 (1992) 828-838
4. Frangogiannis N.G., Smith C.W., and Entman M.L. The inflammatory response in myocardial infarction. Cardiovasc. Res. 53 1 (2002) 31-47
5. Gyongyosi M., et al. NOGA-guided analysis of regional myocardial perfusion abnormalities treated with intramyocardial injections of plasmid encoding vascular endothelial growth factor A-165 in patients with chronic myocardial ischemia: subanalysis of the EUROINJECT-ONE multicenter double-blind randomized study. Circulation 112 9 Suppl (2005) I157-I165
6. Hampton T.G., et al. Basic FGF reduces stunning via a NOS2-dependent pathway in coronary-perfused mouse hearts. Am. J. Physiol, Heart Circ. Physiol. 279 1 (2000) H260-H268
7. Heilmann C., et al. Comparison of protein with DNA therapy for chronic myocardial ischemia using fibroblast growth factor-2. Eur. J. Cardio-thorac. Surg. 22 6 (2002) 957-964
8. Heilmann C.A., et al. Gene therapy in cardiac surgery: intramyocardial injection of naked plasmid DNA for chronic myocardial ischemia. Eur. J. Cardio-thorac. Surg. 24 5 (2003) 785-793
9. Hoefer I.E., van Royen N., Buschmann I.R., Piek J.J., and Schaper W. Time course of arteriogenesis following femoral artery occlusion in the rabbit. Cardiovasc. Res. 49 3 (2001) 609-617
10. Ito W.D., et al. Monocyte chemotactic protein-1 increases collateral and peripheral conductance after femoral artery occlusion. Circ. Res. 80 6 (1997) 829-837
11. Khurana R., and Simons M. Insights from angiogenesis trials using fibroblast growth factor for advanced arteriosclerotic disease. Trends Cardiovasc. Med. 13 3 (2003) 116-122
12. Lee P.C., et al. Impaired wound healing and angiogenesis in eNOS-deficient mice. Am. J. Physiol. 277 4 Pt 2 (1999) H1600-H1608
13. Liu L., et al. Adult cardiomyocytes express functional high-affinity receptors for basic fibroblast growth factor. Am. J. Physiol. 268 5 Pt 2 (1995) H1927-H1938
14. Marczin N., et al. Monocyte-induced downregulation of nitric oxide synthase in cultured aortic endothelial cells. Arterioscler. Thromb. Vasc. Biol. 16 9 (1996) 1095-1103
15. Matsunaga T., et al. Ischemia-induced coronary collateral growth is dependent on vascular endothelial growth factor and nitric oxide. Circulation 102 25 (2000) 3098-3103
16. Murohara T., et al. Nitric oxide synthase modulates angiogenesis in response to tissue ischemia. J. Clin. Invest. 101 11 (1998) 2567-2578
17. Nikolaidis L.A., et al. Mechanisms whereby rapid RV pacing causes LV dysfunction: perfusion-contraction matching and NO. Am. J. Physiol, Heart Circ. Physiol. 281 6 (2001) H2270-H2281
18. Padua R.R., Sethi R., Dhalla N.S., and Kardami E. Basic fibroblast growth factor is cardioprotective in ischemia-reperfusion injury. Mol. Cell. Biochem. 143 2 (1995) 129-135
19. Ren J.F., et al. Multiplane transesophageal and intracardiac echocardiography in large swine: imaging technique, normal values, and research applications. Echocardiography 14 2 (1997) 135-148
20. Sarkar N., et al. Nonsurgical direct delivery of plasmid DNA into rat heart: time course, dose response, and the influence of different promoters on gene expression. J. Cardiovasc. Pharmacol. 39 2 (2002) 215-224
21. Schaper W. Coronary collateral development: concepts and hypotheses. In: Schaper W., and Schaper J. (Eds). Collateral Circulation (1993), Kluwer Academic Publishers, Dordrecht 41-64
22. Schulz R., Kelm M., and Heusch G. Nitric oxide in myocardial ischemia/reperfusion injury. Cardiovasc. Res. 61 3 (2004) 402-413
23. Sellke F.W., and Ruel M. Vascular growth factors and angiogenesis in cardiac surgery. Ann. Thorac. Surg. 75 2 (2003) S685-S690
24. Stowe D.F., et al. Segment stroke work and metabolism depend on coronary blood flow in the pig. Am. J. Physiol. 234 5 (1978) H597-H607
25. Tio R.A., et al. Intramyocardial gene therapy with naked DNA encoding vascular endothelial growth factor improves collateral flow to ischemic myocardium. Hum. Gene Ther. 10 18 (1999) 2953-2960
26. Voskuil M., et al. Modulation of collateral artery growth in a porcine hindlimb ligation model using MCP-1. Am. J. Physiol, Heart Circ. Physiol. 284 4 (2003) H1422-H1428
27. Zach O., et al. Expression of a chemotactic cytokine (MCP-1) in cerebral capillary endothelial cells in vitro. Endothelium 5 3 (1997) 143-153
28. Zhang H., and Issekutz A.C. Down-modulation of monocyte transendothelial migration and endothelial adhesion molecule expression by fibroblast growth factor: reversal by the anti-angiogenic agent SU6668. Am. J. Pathol. 160 6 (2002) 2219-2230