Endogenous TNFα mediates cell survival and chemotherapy resistance by activating the PI3K/Akt pathway in acute lymphoblastic leukemia cells [12]

Leukemia

Volumn 20, Issue 5, 2006, Pages 900-904

  Gu, L ^a   Findley, H W ^a   Zhu, N ^a   Zhou, M ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; DOXORUBICIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; ANTINEOPLASTIC AGENT; CHROMONE DERIVATIVE; MORPHOLINE DERIVATIVE; SMALL INTERFERING RNA;

ACUTE LYMPHOBLASTIC LEUKEMIA; APOPTOSIS; CANCER RESISTANCE; CELL SURVIVAL; CELL TYPE; CLONOGENIC ASSAY; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; DRUG SENSITIVITY; ENZYME ACTIVATION; HUMAN; IMMUNOPHENOTYPING; LETTER; LEUKEMIA CELL LINE; NEUROPROTECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ACUTE LYMPHOCYTIC LEUKEMIA; DRUG ANTAGONISM; DRUG EFFECT; DRUG RESISTANCE; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CELL LINE, TUMOR; CELL SURVIVAL; CHROMONES; DRUG RESISTANCE, NEOPLASM; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE; MORPHOLINES; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33646138499     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2404160     Document Type: Letter

References (8)

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