Anatomical mapping of human herpesvirus reservoirs of infection

Modern Pathology

Volumn 19, Issue 5, 2006, Pages 726-737

  Chen, Tiansheng ^a   Hudnall, S David ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Cytomegalovirus; Epstein Barr virus; Herpes simplex virus; Human herpesvirus 6; Human herpesvirus 7; Human herpesvirus 8; Varicella zoster virus

Indexed keywords

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADOLESCENT; ADULT; AGED; ARTICLE; AUTOPSY; CLINICAL ARTICLE; CYTOMEGALOVIRUS; EPSTEIN BARR VIRUS; FEMALE; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HERPES VIRUS INFECTION; HUMAN; HUMAN HERPESVIRUS 6; HUMAN HERPESVIRUS 7; HUMAN HERPESVIRUS 8; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; MALE; NONHUMAN; PATHOLOGICAL ANATOMY; PERSISTENT VIRUS INFECTION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE DISTRIBUTION; VARICELLA ZOSTER VIRUS; VIRUS DETECTION;

ADOLESCENT; ADULT; AGED; ANAL CANAL; AUTOPSY; CYTOMEGALOVIRUS; DNA, VIRAL; FEMALE; HERPESVIRIDAE; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 1, HUMAN; HERPESVIRUS 2, HUMAN; HERPESVIRUS 3, HUMAN; HERPESVIRUS 4, HUMAN; HERPESVIRUS 6, HUMAN; HERPESVIRUS 7, HUMAN; HERPESVIRUS 8, HUMAN; HUMANS; INTESTINES; MALE; MIDDLE AGED; NASAL MUCOSA; NERVOUS SYSTEM; THYROID GLAND;

EID: 33646129235     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.3800584     Document Type: Article

References (57)

1. Hudnall SD, Chen T, Tyring SK. Species identification of all eight human herpesviruses with a single nested PCR assay. J Virol Methods 2004;116:19-26.
2. Ehlers B, Borchers K, Grund C, et al. Detection of new DNA polymerase genes of known and potentially novel herpesviruses by PCR with degenerate and deoxyinosine-substituted primers. Virus Genes 1999;18:211-220.
3. Thompson RL, Sawtell NM. Herpes simplex virus type 1 latency-associated transcript gene promotes neuronal survival. J Virol 2001;75:6660-6675.
4. Bustos DE, Atherton SS. Detection of herpes simplex virus type 1 in human ciliary ganglia. Invest Ophthalmol Vis Sci 2002;43:2244-2249.
5. Thompson RL, Sawtell NM. Replication of herpes simplex virus type 1 within trigeminal ganglia is required for high frequency but not high viral genome copy number latency. J Virol 2000;74:965-974.
6. Lokensgard JR, Bloom DC, Dobson AT, et al. Long-term promoter activity during herpes simplex virus latency. J Virol 1994;68:7148-7158.
7. Daheshia M, Feldman LT, Rouse BT. Herpes simplex virus latency and the immune response. Curr Opin Microbiol 1998;1:430-435.
8. Lehner T, Wilton JM, Shillitoe EJ. Immunological basis for latency, recurrences and putative oncogenicity of herpes simplex virus. Lancet 1975;2:60-62.
9. Theil D, Horn AK, Derfuss T, et al. Prevalence and distribution of HSV-1, VZV, and HHV-6 in human cranial nerve nuclei III, FV, VI, VII, and XII. J Med Virol 2004;74:102-106.
10. Theil D, Paripovic I, Derfuss T, et al. Dually infected (HSV-1/VZV) single neurons in human trigeminal ganglia. Ann Neurol 2003;54:678-682.
11. Mitchell BM, Bloom DC, Cohrs RJ, et al. Herpes simplex virus-1 and varicella-zoster virus latency in ganglia. J Neurovirol 2003;9:194-204.
12. Gordon L, McQuaid S, Cosby SL. Detection of herpes simplex virus (types 1 and 2) and human herpesvirus 6 DNA in human brain tissue by polymerase chain reaction. Clin Diagn Virol 1996;6:33-40.
13. Croen KD, Ostrove JM, Dragovic LJ, et al. Patterns of gene expression and sites of latency in human nerve ganglia are different for varicella-zoster and herpes simplex viruses. Proc Natl Acad Sci USA 1988; 85:9773-9777.
14. Annunziato PW, Lungu O, Panagiotidis C. Varicella zoster virus in human and rat tissue specimens. Arch Virol Suppl 2001;17:135-142.
15. Abendroth A, Arvin A. Varicella-zoster virus immune evasion. Immunol Rev 1999;168:143-156.
16. Lungu O, Annunziato PW, Gershon A, et al. Reactivated and latent varicella-zoster virus in human dorsal root ganglia. Proc Natl Acad Sci USA 1995;92: 10980-10984.
17. Gratama JW, Oosterveer MA, Zwaan FE, et al. Eradication of Epstein-Barr virus by allogeneic bone marrow transplantation: implications for sites of viral latency. Proc Natl Acad Sci USA 1988;85:8693-8696.
18. Schmidt CW, Misko IS. The ecology and pathology of Epstein-Barr virus. Immunol Cell Biol 1995;73:489-504.
19. Jarvis MA, Nelson JA. Mechanisms of human cytomegalovirus persistence and latency. Front Biosci 2002;7:1575-1582.
20. Bolovan-Fritts CA, Mocarski ES, Wiedeman JA. Peripheral blood CD14(+) cells from healthy subjects carry a circular conformation of latent cytomegalovirus genome. Blood 1999;93:394-398.
21. Adam E, Melnick JL, DeBakey ME. Cytomegalovirus infection and atherosclerosis. Cent Eur J Public Health 1997;5:99-106.
22. Guetta E, Guetta V, Shibutani T, et al. Monocytes harboring cytomegalovirus: interactions with endothelial cells, smooth muscle cells, and oxidized low-density lipoprotein. Possible mechanisms for activating virus delivered by monocytes to sites of vascular injury. Circ Res 1997;81:8-16.
23. Kondo K, Mocarski ES. Cytomegalovirus latency and latency specific transcription in hematopoietic progenitors. Scand J Infect Dis Suppl 1995;99:63-67.
24. Kondo K, Kaneshima H, Mocarski ES. Human cytomegalovirus latent infection of granulocyte-macrophage progenitors. Proc Natl Acad Sci USA 1994;91:11879-11883.
25. Kondo K, Xu J, Mocarski ES. Human cytomegalovirus latent gene expression in granulocyte-macrophage progenitors in culture and in seropositive individuals. Proc Natl Acad Sci USA 1996;93:11137-11142.
26. Sindre H, Tjoonnfjord GE, Rollag H, et al. Human cytomegalovirus suppression of and latency in early hematopoietic progenitor cells. Blood 1996;88:4526-4533.
27. Kondo K, Mocarski ES. Cytomegalovirus latency and latency-specific transcription in hematopoietic progenitors. Scand J Infect Dis Suppl 1995;99:63-67.
28. Fajac A, Vidaud M, Lebargy F, et al. Evaluation of human cytomegalovirus latency in alveolar macrophages. Am J Respir Crit Care Med 1994;149:495-499.
29. Taylor-Wiedeman J, Sissons JG, Borysiewicz LK, et al. Monocytes are a major site of persistence of human cytomegalovirus in peripheral blood mononuclear cells. J Gen Virol 1991;72:2059-2064.
30. Toorkey CB, Carrigan DR. Immunohistochemical detection of an immediate early antigen of human cytomegalovirus in normal tissues. J Infect Dis 1989;160:741-751.
31. Jordan MC. Latent infection and the elusive cytomegalovirus. Rev Infect Dis 1983;5:205-215.
32. Sissons JG, Bain M, Wills MR. Latency and reactivation of human cytomegalovirus. J Infect 2002;44:73-77.
33. Dworniczak S, Ziora D, Kaminski J, et al. Bronchoalveolar lavage cells are the most significant reservoir of human cytomegalovirus genome. Pneumonol Alergol Pol 2003;71:512-520.
34. Khaiboullina SF, Maciejewski JP, Crapnell K, et al. Human cytomegalovirus persists in myeloid progenitors and is passed to the myeloid progeny in a latent form. Br J Haematol 2004;126:410-417.
35. Kraat YJ, Hendrix MG, Wijnen RM, et al. Detection of latent human cytomegalovirus in organ tissue and the correlation with serological status. Transpl Int 1992; 5(Suppl 1):S613-S616.
36. Hendrix MG, Dormans PH, Kitslaar P, et al. The presence of cytomegalovirus nucleic acids in arterial walls of atherosclerotic and nonatherosclerotic patients. Am J Pathol 1989;134:1151-1157.
37. Hendrix RM, Wagenaar M, Slobbe RL, et al. Widespread presence of cytomegalovirus DNA in tissues of healthy trauma victims. J Clin Pathol 1997;50:59-63.
38. Kondo K, Shimada K, Sashihara J, et al. Identification of human herpesvirus 6 latency-associated transcripts. J Virol 2002;76:4145-4151.
39. Kondo K, Kondo T, Okuno T, et al. Latent human herpesvirus 6 infection of human monocytes/macrophages. J Gen Virol 1991;72:1401-1408.
40. Cuomo L, Angeloni A, Zompetta C, et al. Human herpesvirus 6 variant A, but not variant B, infects EBV-positive B lymphoid cells, activating the latent EBV genome through a BZLF-1-dependent mechanism. AIDS Res Hum Retroviruses 1995;11:1241-1245.
41. Maric I, Bryant R, Abu-Asab M, et al. HHV-6 associated acute lymphadenitis in immunocompetent adults. Mod Pathol 2004;17:1427-1433.
42. Luppi M, Barozzi P, Garber R, et al. Expression of human herpesvirus-6 antigens in benign and malignant lymphoproliferative diseases. Am J Pathol 1998;153:815-823.
43. Goodman AD, Mock DJ, Powers JM, et al. Human herpesvirus 6 genome and antigen in acute multiple sclerosis lesions. J Infect Dis 2003;187:1365-1376.
44. Collot S, Petit B, Bordessoule D, et al. Real-time PCR for quantification of human herpesvirus 6 DNA from lymph nodes and saliva. J Clin Microbiol 2002;40:2445-2451.
45. Di Luca D, Mirandola P, Ravaioli T, et al. Human herpesviruses 6 and 7 in salivary glands and shedding in saliva of healthy and human immunodeficiency virus positive individuals. J Med Virol 1995;45:462-468.
46. Sumiyoshi Y, Kikuchi M, Ohshima K, et al. A case of human herpesvirus-6 lymphadenitis with infectious mononucleosis-like syndrome. Pathol Int 1995;45:947-951.
47. Randhawa PS, Jenkins FJ, Nalesnik MA, et al. Herpesvirus 6 variant A infection after heart transplantation with giant cell transformation in bile ductular and gastroduodenal epithelium. Am J Surg Pathol 1997;21:847-853.
48. Knox KK, Carrigan DR. Active HHV-6 infection in the lymph nodes of HIV-infected patients: in vitro evidence that HHV-6 can break HIV latency. J Acquir Immune Defic Syndr Hum Retrovirol 1996;11:370-378.
49. Kempf W, Adams V, Wey N, et al. CD68+ cells of monocyte/macrophage lineage in the environment of AIDS-associated and classic sporadic Kaposi sarcoma are singly or doubly infected with human herpesviruses 7 and 6B. Proc Natl Acad Sci USA 1997;94:7600-7605.
50. Kempf W, Muller B, Maurer R, et al. Increased expression of human herpesvirus 7 in lymphoid organs of AIDS patients. J Clin Virol 2000;16:193-201.
51. Yadav M, Nambiar S, Khoo SP, et al. Detection of human herpesvirus 7 in salivary glands. Arch Oral Biol 1997;42:559-567.
52. Kempf W, Adams V, Mirandola P, et al. Persistence of human herpesvirus 7 in normal tissues detected by expression of a structural antigen. J Infect Dis 1998;178:841-845.
53. Chen RL, Lin JC, Wang PJ, et al. Human herpesvirus 8-related childhood mononucleosis: a series of three cases. Pediatr Infect Dis J 2004;23:671-674.
54. Diamond C, Brodie SJ, Krieger JN, et al. Human herpesvirus 8 in the prostate glands of men with Kaposi's sarcoma. J Virol 1998;72:6223-6227.
55. Blasig C, Zietz C, Haar B, et al. Monocytes in Kaposi's sarcoma lesions are productively infected by human herpesvirus 8. J Virol 1997;71:7963-7968.
56. Decker LL, Shankar P, Khan G, et al. The Kaposi sarcoma-associated herpesvirus (KSHV) is present as an intact latent genome in KS tissue but replicates in the peripheral blood mononuclear cells of KS patients. J Exp Med 1996;184:283-288.
57. Corbellino M, Poirel L, Bestetti G, et al. Restricted tissue distribution of extralesional Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS patients with Kaposi's sarcoma. AIDS Res Hum Retroviruses 1996;12:651-657.