Tracheal Allograft Transplantation in Rats: The Role of Different Immunosuppressants on Preservation of Respiratory Epithelium

Transplantation Proceedings

Volumn 38, Issue 3, 2006, Pages 741-744

  Schrepfer, S ^a   Deuse, T ^a   Sydow, K ^a   Schafer H ^b   Detter, C ^a   Reichenspurner, H ^a  

^a UNIVERSITY HEART CENTER HAMBURG   (Germany)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2 CYANO 3 HYDROXY N [4 (TRIFLUOROMETHYL)PHENYL] 6 HEPTYNAMIDE; CYTOKINE; IMMUNOSUPPRESSIVE AGENT; RAPAMYCIN; TACROLIMUS;

ALLOTRANSPLANTATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRONCHIOLITIS OBLITERANS; CELL LOSS; CELL PROLIFERATION; CONTROLLED STUDY; DONOR; GRAFT RECIPIENT; GREATER OMENTUM; HETEROTOPIC TRANSPLANTATION; IMMUNOSUPPRESSIVE TREATMENT; ISOGRAFT; MALE; MUCOSA; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATORY EPITHELIUM; TRACHEA; TRACHEA GRAFT; TRACHEA SURGERY;

ANIMALS; IMMUNOSUPPRESSIVE AGENTS; MODELS, ANIMAL; OMENTUM; RATS; RATS, INBRED BN; RATS, INBRED LEW; RESPIRATORY MUCOSA; TRACHEA; TRANSPLANTATION, HOMOLOGOUS; TRANSPLANTATION, ISOGENEIC;

EID: 33646120822     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2006.01.042     Document Type: Article

References (10)

1. Valentine V.G., Robbins R.C., Berry G.J., et al. Actuarial survival of heart-lung and bilateral sequential lung transplant recipients with obliterative bronchiolitis. J Heart Lung Transplant 15 (1996) 371
2. Boehler A., Chamberlain D., Kesten S., et al. Lymphocytic airway infiltration as a precursor to fibrous obliteration in a rat model of bronchiolitis obliterans. Transplantation 64 (1997) 311
3. Paradis I., Yousem S., and Griffith B. Airway obstruction and bronchiolitis obliterans after lung transplantation. Clin Chest Med 14 (1993) 751
4. Dosanjh A., Wan B., Ikonen T., et al. Airway goblet cells and respiratory epithelial injury in an animal model of obliterative airways disease (OAD). Am J Transplant 1 (2001) 321
5. Huang X.H., Reichenspurner H., Shorthouse R., et al. Heterotopic tracheal allograft transplantation. a new model to study the molecular events causing obliterative airway disease (OAD) in rats. J Heart Lung Transplant 14 suppl (1995) 49 [Abstract]
6. Morris R.E., Huang X., Gregory C.R., et al. Studies in experimental models of chronic rejection. use of rapamycin (sirolimus) and isoxazole derivatives (leflunomide and its analogue) for the suppression of graft vascular disease and obliterative bronchiolitis. Transplant Proc 27 (1995) 2068
7. Adams B.F., Berry G.J., Huang X., et al. Immunosuppressive therapies for the prevention and treatment of obliterative airway disease in heterotopic rat trachea allografts. Transplantation 69 (2000) 2260
8. Deuse T., Schrepfer S., and Reichenspurner H. The interaction between FK778 and tacrolimus in the prevention of rat cardiac allograft rejection is dose dependent. Transplantation 77 (2004) 509
9. Fukuda Y., Ferrans V.J., Schoenberger C.I., et al. Patterns of pulmonary structural remodeling after experimental paraquat toxicity. the morphogenesis of intraalveolar fibrosis. Am J Pathol 118 (1984) 452
10. Persson C.G., Erjefalt J.S., Greiff L., et al. Contribution of plasma-derived molecules to mucosal immune defence, disease and repair in the airways. Scand J Immunol 47 (1998) 302