Very low ethanol concentrations affect the viability and growth recovery in post-stationary-phase Staphylococcus aureus populations

Applied and Environmental Microbiology

Volumn 72, Issue 4, 2006, Pages 2627-2636

  Chatterjee, Indranil ^a   Somerville, Greg A ^d   Heilmann, Christine ^b   Sahl, Hans Georg ^c   Maurer, Hans H ^a   Herrmann, Mathias ^a,e  

^a SAARLAND UNIVERSITY   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c UNIVERSITY OF BONN   (Germany)

^d UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^e Building 43 ^*  (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; CELL CULTURE; CONCENTRATION (PROCESS); DRUG PRODUCTS; GROWTH KINETICS; METABOLISM; MICROORGANISMS;

CELL INTEGRITY; CULTURE MEDIA; HUMAN BODY FLUIDS; VLEC CONDITIONS;

ETHANOL;

ACETIC ACID; ALCOHOL; AMINO ACID; ARGININE; GLUTAMIC ACID; ORNITHINE; PROLINE;

BACTERIOLOGY; BACTERIUM; BODY FLUID; CONCENTRATION (COMPOSITION); ETHANOL; POPULATION GROWTH; SCANNING ELECTRON MICROSCOPY;

ACIDITY; AMINO ACID METABOLISM; ARTICLE; BACTERIAL CELL; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIOSTASIS; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CULTURE MEDIUM; NONHUMAN; SCANNING ELECTRON MICROSCOPY; STAPHYLOCOCCUS AUREUS;

AEROBIOSIS; CULTURE MEDIA; DISINFECTANTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; HUMANS; MICROSCOPY, ELECTRON, SCANNING; STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS;

EID: 33646113385     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/AEM.72.4.2627-2636.2006     Document Type: Article

References (42)

1. Barker, C., and S. F. Park. 2001. Sensitization of Listeria monocytogenes to low pH, organic acids, and osmotic stress by ethanol. Appl. Environ. Microbiol. 67:1594-1600.
2. Basu, T., and R. K. Poddar. 1994. Effect of ethanol on Escherichia coli cells. Enhancement of DNA synthesis due to ethanol treatment. Fol. Microbiol. (Praha) 39:3-6.
3. Beeken, K. E., P. M. Dunman, F. McAleese, D. Macapagal, E. Murphy, S. J. Projan, J. S. Blevins, and M. S. Smeltzer. 2004. Global gene expression in Staphylococcus aureus biofilms. J. Bacteriol. 186:4665-4684.
4. Bewles, L. K., and W. L. Ellefson. 1985. Effects of butanol on Clostridium acetobutylicum. Appl. Environ. Microbiol. 50:1165-1170.
5. B controls the environmental stress response but not starvation survival or pathogenicity in a mouse abscess model. J. Bacteriol. 180:6082-6089.
6. Chatterjee, A., and F. E. Young. 1972. Regulation of the bacterial cell wall: isolation and characterization of peptidoglycan mutants of Staphylococcus aureus. J. Bacteriol. 111:220-230.
7. Chatterjee, I., P. Becker, M. Grundmeier, M. Bischoff, G. A. Somerville, G. Peters, B. Sinha, N. Harraghy, R. A. Proctor, and M. Herrmann. 2005. Staphylococcus aureus ClpC is required for stress resistance, aconitase activity, growth recovery, and death. J. Bacteriol. 187:4488-4496.
8. Chiou, R. Y., R. D. Phillips, P. Zhao, M. P. Doyle, and L. R. Beuchat. 2004. Ethanol-mediated variations in cellular fatty acid composition and protein profiles of two genotypically different strains of Escherichia coli O157:H7. Appl. Environ. Microbiol. 70:2204-2210.
9. Dannenberg, C., U. Bierbach, A. Rothe, J. Beer, and D. Korholz. 2003. Ethanol-lock technique in the treatment of bloodstream infections in pediatric oncology patients with Broviac catheter. J. Pediatr. Hematol. Oncol. 25:616-621.
10. Dombek, K. M., and L. O. Ingram. 1984. Effects of ethanol on the Escherichia coli plasma membrane. J. Bacteriol. 157:233-239.
11. Fass, R. J., J. Carleton, C. Watanakunakorn, A. S. Kleiner, and M. Hamburger. 1970. Scanning-beam electron microscopy of cell wall-defective staphylococci. Infect. Immun. 2:504-515.
12. Fried, V. A., and A. Novick. 1973. Organic solvents as probes for the structure and function of the bacterial membrane: effects of ethanol on the wild type and an ethanol-resistant mutant of Escherichia coli K-12. J. Bacteriol. 114:239-248.
13. Good, C. M., and D. J. Tipper. 1972. Conditional mutants of Staphylococcus aureus defective in cell wall precursor synthesis. J. Bacteriol. 111:231-241.
14. Gottig, N., M. E. Pedrido, M. Mendez, E. Lombardia, A. Rovetto, V. Philippe, L. Orsaria, and R. Grau. 2005. The Bacillus subtilis SinR and RapA developmental regulators are responsible for inhibition of spore development by alcohol. J. Bacteriol. 187:2662-2672.
15. Halegoua, S., and M. Inouye. 1979. Translocation and assembly of outer membrane proteins of Escherichia coli. Selective accumulation of precursors and novel assembly intermediates caused by phenethyl alcohol. J. Mol. Biol. 130:39-61.
16. Herrmann, M., M. Weyand, B. Greshake, C. von Eiff, R. A. Proctor, H. H. Scheid, and G. Peters. 1997. Left ventricular assist device infection is associated with increased mortality but is not a contraindication to transplantation. Circulation 95:814-817.
17. B modulates virulence determinant expression and stress resistance: characterization of a functional rsbU strain derived from Staphylococcus aureus 8325-4. J. Bacteriol. 184:5457-5467.
18. Huang, L., C. W. Forsberg, and L. N. Gibbins. 1986. Influence of external pH and fermentation products on Clostridium acetobutylicum intracellular pH and cellular distribution of fermentation products. Appl. Environ. Microbiol. 51:1230-1234.
19. Ingram, L. O., and T. M. Buttke. 1984. Effects of alcohols on micro-organisms. Adv. Microb. Physiol. 25:253-300.
20. John, J. F., and N. L. Barg. 2004. Staphylococcus aureus, p. 443-470. In G. C. Mayhall (ed.), Hospital epidemiology and infection control. Lippincott Williams and Wilkins, Philadelphia, Pa.
21. Knobloch, J. K., K. Bartscht, A. Sabottke, H. Rohde, H. H. Feucht, and D. Mack. 2001. Biofilm formation by Staphylococcus epidermidis depends on functional RsbU, an activator of the sigB operon: differential activation mechanisms due to ethanol and salt stress. J. Bacteriol. 183:2624-2633.
22. Knobloch, J. K., M. A. Horstkotte, H. Rohde, P. M. Kaulfers, and D. Mack. 2002. Alcoholic ingredients in skin disinfectants increase biofilm expression of Staphylococcus epidermidis. J. Antimicrob. Chemother. 49:683-687.
23. B by repression of the negative regulator gene icaR. Infect. Immun. 72:3838-3848.
24. Kohler, C., C. von Eiff, G. Peters, R. A. Proctor, M. Hecker, and S. Engelmann. 2003. Physiological characterization of a heme-deficient mutant of Staphylococcus aureus by a proteomic approach. J. Bacteriol. 185:6928-6937.]
25. Lacy, R. W. 1968. Antibacterial action of human skin. In vivo effect of acetone, alcohol and soap on behaviour of Staphylococcus aureus. Br. J. Exp. Pathol. 49:209-215.
26. Lew, D., J. Schrenzel, P. Francois, and P. Vaudaux. 2001. Pathogenesis, prevention, and therapy of staphylococcal prosthetic infections. Curr. Clin. Top. Infect. Dis. 21:252-270.
27. Lowy, F. D. 1998. Staphylococcus aureus infections. N. Engl. J. Med. 339:520-532.
28. Lugtenberg, E. J. J., H. J. W. Wijsman, and D. V. Zaane. 1973. Properties of a D-glutamic acid-requiring mutant of Escherichia coli. J. Bacteriol. 114:499-506.
29. Maurer, H. H., T. Kraemer, C. Kratzsch, L. D. Paul, F. T. Peters, D. Springer, R. F. Staack, and A. A. Weber. 2002. What is the appropriate analytical strategy for effective management of intoxicated patients?, p. 61-75. In M. Balikova and E. Navakova (ed.), Proceedings of the 39th International TIAFT Meeting in Prague 2001. Charles University, Prague, Czech Republic.
30. NCCLS. 2002. Performance standards for antimicrobial susceptibility testing; twelfth informational supplement. NCCLS document M100-S12. NCCLS, Wayne, Pa.
31. Pag, U., M. Oedenkoven, N. Papo, Z. Oren, Y. Shai, and H.-G. Sahl. 2004. In vitro activity and mode of action of diastereomeric antimicrobial peptides against bacterial clinical isolates. J. Antimicrob. Chemother. 53:230-239.
32. Resch, A., R. Rosenstein, C. Nerz, and F. Götz. 2005. Differential gene expression profiling of Staphylococcus aureus cultivated under biofilm and planktonic conditions. Appl. Environ. Microbiol. 71:2663-2676. 0
33. Schleifer, K. H., and O. Kandier. 1972. Peptidoglycan types of bacterial cell walls and their taxonomic implications. Bacteriol. Rev. 36:407-477.
34. Seifert, H. 2005. Central venous catheters, p. 293-326. In H. Seifert, B. Jansen, and B. M. Farr (ed.), Catheter-related infections, 2nd ed., Marcel Dekker, New York, N.Y.
35. Seiler, D. A. L., and N. J. Russell. 1991. Ethanol as a food preservative, p. 153-171. In N. J. Russell and G. W. Gould (ed.), Food preservatives. Blackie, London, England.
36. Silveira, M. G., M. Baumgartner, F. M. Rombouts, and T. Abee. 2004. Effect of adaptation to ethanol on cytoplasmic and membrane protein profiles of Oenococcus oeni. Appl. Environ. Microbiol. 70:2748-2755.
37. Silvestri, L. G., and L. R. Hill. 1965. Agreement between deoxyribonucleic acid base composition and taxometric classification of gram-positive cocci. J. Bacteriol. 90:136-140.
38. Somerville, G. A., M. S. Chaussee, C. I. Morgan, J. R. Fitzgerald, D. W. Dorward, L. J. Reitzer, and J. M. Musser. 2002. Staphylococcus aureus aconitase inactivation unexpectedly inhibits post-exponential-phase growth and enhances stationary-phase survival. Infect. Immun. 70:6373-6382.
39. Somerville, G. A., B. Saïd-Salim, J. M. Wickman, S. J. Raffel, B. N. Kreiswirth, and J. M. Musser. 2003. Correlation of acetate catabolism and growth yield in Staphylococcus aureus: implications for host-pathogen interactions. Infect. Immun. 71:4724-4732.
40. Terracciano, J. S., and E. R. Kashket. 1986. Intracellular conditions required for the initiation of solvent production by Clostridium acetobutylicum. Appl. Environ. Microbiol. 52:86-91.
41. Wolz, C., C. Goerke, R. Landmann, W. Zimmerli, and U. Fluckiger. 2002. Transcription of clumping factor A in attached and unattached Staphylococcus aureus in vitro and during device-related infection. Infect. Immun. 70:2758-2762.
42. Yao, Y., D. E. Sturdevant, and M. Otto. 2005. Genome-wide analysis of gene expression in Staphylococcus epidermidis biofilms: insights into the patho-physiology of S. epidermidis biofilms and the role of phenol-soluble modulins in formation of biofilms. J. Infect. Dis. 191:289-298.