Experimental therapies for hypoxic pulmonary vasoconstriction

Shock

Volumn 25, Issue 3, 2006, Pages 314-

  Maybauer, Dirk M ^a   Maybauer, Marc O ^a   Traber, Daniel L ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; NITRIC OXIDE; PHOSPHODIESTERASE V INHIBITOR; RHO KINASE INHIBITOR; VASODILATOR AGENT;

ACUTE LUNG INJURY; ADD ON THERAPY; DRUG EFFECT; ENZYME INHIBITION; EXPERIMENTAL THERAPY; HUMAN; HYPERVENTILATION; HYPOXIC LUNG VASOCONSTRICTION; METHEMOGLOBINEMIA; NONHUMAN; NOTE; PULMONARY HYPERTENSION; SHOCK; ANIMAL; ANOXIA; LUNG CIRCULATION; PHYSIOLOGY; VASOCONSTRICTION;

ANIMALS; ANOXIA; HYPERTENSION, PULMONARY; PULMONARY CIRCULATION; VASOCONSTRICTION; VASODILATOR AGENTS;

EID: 33646110758     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.shk.0000208806.65374.75     Document Type: Note

References (7)

1. Morrell ED, Tsai BM, Crisostomo PR, Hammoud ZT, Meldrum DR: Experimental therapies for hypoxia-induced pulmonary hypertension during acute lung injury. Shock 2006. In press.
2. von Euler U, Liljestrand, G: Observations on the pulmonary arterial blood pressure in the cat. Acta Physiol Scand 12:301-320, 1946.
3. Hulme JT, Coppock EA, Felipr A, Martens JR, Tamkun MM: Oxygen sensitivity of cloned voltage-gated K(+) channels expressed in the pulmonary vasculature. Circ Res 85:489-497, 1999.
4. Zharikov SI, Block ER: Association of L-arginine transporters with fodrin: implications for hypoxic inhibition of arginine uptake. Am J Physiol 278:L111-L117, 2000.
5. Szabo C: The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury. Shock 6:79-88, 1996.
6. Yu YM, Ryan CM, Castillo L, Lu XM, Beaumier L, Tompkins RG, Young VR: Arginine and ornithine kinetics in severely burned patients: increased rate of arginine disposal. Am J Physiol Endocrinol Metab 280:E509-E517, 2001.
7. Xia Y, Dawson VL, Dawson TM, Snyder SH, Zweier JL: Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury. Proc Natl Acad Sci U S A 93:6770-6774, 1996.