RECS1 is a negative regulator of matrix metalloproteinase-9 production and aged RECS1 knockout mice are prone to aortic dilation

Circulation Journal

Volumn 70, Issue 5, 2006, Pages 615-624

  Zhao, Hanjun ^a,c   Ito, Akihiko ^b   Sakai, Naohiko ^a   Matsuzawa, Yuji ^d   Yamashita, Shizuya ^a   Nojima, Hiroshi ^c  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d OSAKA UNIVERSITY   (Japan)

Author keywords

Aging; Aneurysm; Cystic medial degeneration; Matrix metalloproteinase 2; Matrix metalloproteinase 9; RECS1

Indexed keywords

GELATINASE A; GELATINASE B;

ANEURYSM; ANIMAL CELL; ANIMAL TISSUE; AORTA; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME DEGRADATION; ENZYME SYNTHESIS; EXTRACELLULAR MATRIX; GENE; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PROTEIN FUNCTION; VASODILATATION; WESTERN BLOTTING; WILD TYPE; ZYMOGRAPHY;

AGING; ANIMALS; AORTA; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASES; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MYOCYTES, SMOOTH MUSCLE; STRESS, MECHANICAL; VASODILATION;

EID: 33646079377     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.70.615     Document Type: Article

References (24)

1. Galis ZS, Khatri JJ. Matrix metalloproteinases in vascular remodeling and atherogenesis: The good, the bad, and the ugly. Circ Res 2002; 90: 251-262.
2. Higo S, Uematsu M, Yamagishi M, Ishibashi-Ueda H, Awata M, Morozumi T, et al. Elevation of plasma matrix metalloproteinase-9 in the culprit coronary artery in patients with acute myocardial infarction: Clinical evidence from distal protection. Circ J 2005; 69: 1180-1185.
3. Noji Y, Shimizu M, Ino H, Higashikata T, Yamaguchi M, Nohara A, et al. Increased circulating matrix metalloproteinase-2 in patients with hypertrophic cardiomyopathy with systolic dysfunction. Circ J 2004; 68: 355-360.
4. Patel MI, Melrose J, Ghosh P, Appleberg M. Increased synthesis of matrix metalloproteinases by aortic smooth muscle cells is implicated in the etiopathogenesis of abdominal aortic aneurysms. J Vasc Surg 1996; 24: 82-92.
5. Bunton TE, Biery NJ, Myers L, Gayraud B, Ramirez F, Dietz HC. Phenotypic alteration of vascular smooth muscle cells precedes elastolysis in a mouse model of Marfan syndrome. Circ Res 2001; 88: 37-43.
6. Chew DK, Conte MS, Khalil RA. Matrix metalloproteinase-specific inhibition of Ca2+ entry mechanisms of vascular contraction. J Vasc Surg 2004; 40: 1001-1110.
7. Erdheim J. Medionecrosis aortae idiopathica. Virchows Arch Pathol Anat 1929; 273: 454-479.
8. Erdheim J. Medionecrosis aortae idiopathica cystica. Virchows Arch Pathol Anat 1930; 276: 187-229.
9. Schlatmann TJ, Becker AE. Histologic changes in the normal aging aorta: Implications for dissecting aortic aneurysm. Am J Cardiol 1977; 39: 13-20.
10. Schlatmann TJ, Becker AE. Pathogenesis of dissecting aneurysm of aorta: Comparative histopathologic study of significance of medial changes. Am J Cardiol 1977; 39: 21-26.
11. Larson EW, Edwards WD. Risk factors for aortic dissection: A necropsy study of 161 cases. Am J Cardiol 1984; 53: 849-855.
12. Hirst AE, Gore I. Editorial: Is cystic medionecrosis the cause of dissecting aortic aneurysm? Circulation 1976; 53: 915-916.
13. Zhao H, Ito A, Kimura HS, Yabuta N, Sakai N, Ikawa M, et al. RECS1 deficiency in mice induces susceptibility to cystic medial degeneration. Genes Genet Syst 2006; 81: 41-50.
14. Segura AM, Luna RE, Horiba K, Stetler-Stevenson WG, McAllister HA Jr, Willerson JT, et al. Immunohistochemistry of matrix metalloproteinases and their inhibitors in thoracic aortic aneurysms and aortic valves of patients with Marfan's syndrome. Circulation 1998; 98(Suppl 19): II-331-II-338.
15. Yoshisue H, Suzuki K, Kawabata A, Ohya T, Zhao H, Sakurada K, et al. Large scale isolation of non-uniform shear stress-responsive genes from cultured human endothelial cells through the preparation of a subtracted cDNA library. Atherosclerosis 2002; 162: 323-334.
16. Lavigne MC, Malech HL, Holland SM, Leto TL. Genetic demonstration of p47phox-dependent superoxide anion production in murine vascular smooth muscle cells. Circulation 2001; 104: 79-84.
17. Brown PD, Levy AT, Margulies IM, Liotta LA, Stetler-Stevenson WG. Independent expression and cellular processing of Mr 72,000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines. Cancer Res 1990; 50: 6184-6191.
18. Ammarguellat FZ, Gannon PO, Amiri F, Schiffrin EL. Fibrosis, matrix metalloproteinases, and inflammation in the heart of DOCA-salt hypertensive rats: Role of ET(A) receptors. Hypertension 2002; 39: 679-684.
19. Baram D, Vaday GG, Salamon P, Drucker I, Hershkoviz R, Mekori YA. Human mast cells release metalloproteinase-9 on contact with activated T cells: Juxtacrine regulation by TNF-alpha. J Immunol 2001; 167: 4008-4016.
20. Longo GM, Xiong W, Greiner TC, Zhao Y, Fiotti N, Baxter BT. Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms. J Clin Invest 2002; 110: 625-632.
21. Juliano RL, Haskill S. Signal transduction from the extracellular matrix. J Cell Biol 1993; 120: 577-585.
22. Moon SK, Cha BY, Lee YC, Nam KS, Runge MS, Patterson C, et al. Age-related changes in matrix metalloproteinase-9 regulation in cultured mouse aortic smooth muscle cells. Exp Gerontol 2004; 39: 123-131.
23. Lindholt JS, Vammen S, Fasting H, Henneberg EW, Heickendorff L. The plasma level of matrix metalloproteinase 9 may predict the natural history of small abdominal aortic aneurysms: A preliminary study. Eur J Vasc Endovasc Surg 2000; 20: 281-285.
24. Eugster T, Huber A, Obeid T, Schwegler I, Gurke L, Stierli P. Aminoterminal propeptide of type III procollagen and matrix metalloproteinases-2 and -9 failed to serve as serum markers for abdominal aortic aneurysm. Eur J Vasc Endovasc Surg 2005; 29: 378-382.